Cervical VertebraeNCT07653542
Correlation Study Between Cervical Vertebrae Volume and Skeletal Maturational Stage in Egyptian Females
An observational study of Cervical Vertebrae, run by Cairo University at 1 site in Egypt.
Trial summary
Correlation between cervical vertebrae volume with maturational stage through CBCT Read more about this study
- Who is it for?
- Ages 10 to 25 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Cervical Vertebrae
- What is being tested?
- CBCT
- Type of treatment
- Surgery or procedure
- How many people
- 131 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jul 2024to 1 Jan 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 25 years
- Women only
- Healthy volunteers accepted
- Child, Adult
Study population: CBCT Radiographs of Egyptian Female patients
Who may be able to join
- CBCT Radiographs should have the following criteria :
- Female patients, age range from 10-25 years .
- Patients free of any serious illness.
- Patients with no cleft lip or palate.
- Patients with no previous trauma or injury in the head and neck region.
Who cannot join
- Patients suffering from congenital or acquired malformations affecting cervical vertebrae.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Correlation Between Cervical Vertebrae Volume Parameters and the Skeletal Maturational Stages in a Sample of Egyptian Female Patients: Cross-sectional Study
Correlation between cervical vertebrae volume with maturational stage through CBCT
- Conditions
- Cervical Vertebrae
- Being tested
- CBCT
- Keywords
- cervical vertebrae, skeletal maturation, vertebral volume, CBCT segmentation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
CBCTRadiation
CBCT Radiographs of Egyptian Female patients will be selected from the patients' database at the Faculty of Dentistry, Cairo University.
The CBCT Radiographs data will be reconstructed using 3D imaging software (3D Slicer ).
The body of the 2nd, 3rd, and 4th vertebra will be cropped and other structures will be deleted.
Each vertebra will be isolated using split mask tool, then 3D format of each vertebra will be obtained, and its 3D volume in mm³ will be recorded using 3D object properties.
then evaluate the association between cervical vertebrae volume and maturation stages assessed using the CVM I
| Study group | Role | What they receive |
|---|---|---|
| CBCT radiograph for Female Egyptian | Not described Receives: Radiation: CBCT |
What is being measured
The primary outcome is the main question the study is designed to answer.
clinical correlation between cervical vertebrae volume and patient's maturational stage
the data (volume of cervical vertebrae C2, C3 and C4) is collected from the CBCT of the patient on the day of arrival of the radiograph
Measured: Data is collected on Day 1 No follow up is needed because it is an observational
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2026
- Study start1 Jul 2024
- Primary completion1 Oct 2025
- Study completion1 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (6)Papers the sponsor has linked to this study.
- Other trials for Cervical VertebraeStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 131 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Rony Abdelbaest, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07653542
- Sponsor's protocol ID
- 8888
- Status last verified
- Jun 2026
- First submitted
- 14 May 2026
- Last updated
- 17 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Gabriel DB, Southard KA, Qian F, Marshall SD, Franciscus RG, Southard TE. Cervical vertebrae maturation method: poor reproducibility. Am J Orthod Dentofacial Orthop. 2009 Oct;136(4):478.e1-7; discussion 478-80. doi: 10.1016/j.ajodo.2007.08.028.
PubMed 19815136Baccetti T, Franchi L, McNamara JA Jr. An improved version of the cervical vertebral maturation (CVM) method for the assessment of mandibular growth. Angle Orthod. 2002 Aug;72(4):316-23. doi: 10.1043/0003-3219(2002)0722.0.CO;2.
PubMed 12169031Franchi L, Baccetti T, McNamara JA Jr. Mandibular growth as related to cervical vertebral maturation and body height. Am J Orthod Dentofacial Orthop. 2000 Sep;118(3):335-40. doi: 10.1067/mod.2000.107009.
PubMed 10982936San Roman P, Palma JC, Oteo MD, Nevado E. Skeletal maturation determined by cervical vertebrae development. Eur J Orthod. 2002 Jun;24(3):303-11. doi: 10.1093/ejo/24.3.303.
PubMed 12143094Hunter CJ. The correlation of facial growth with body height and skeletal maturation at adolescence. Angle Orthod. 1966 Jan;36(1):44-54. doi: 10.1043/0003-3219(1966)0362.0.CO;2. No abstract available.
PubMed 5218761Hagg U, Taranger J. Maturation indicators and the pubertal growth spurt. Am J Orthod. 1982 Oct;82(4):299-309. doi: 10.1016/0002-9416(82)90464-x.
PubMed 6961802
Study at a glance
From the registry record, last updated by the sponsor on 17 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Correlation Between Cervical Vertebrae Volume Parameters and the Skeletal Maturational Stages in a Sample of Egyptian Female Patients: Cross-sectional Study
- ClinicalTrials.gov ID
- NCT07653542
- Acronym / sponsor ID
- 8888
- Conditions
- Cervical Vertebrae
- Keywords
- cervical vertebrae, skeletal maturation, vertebral volume, CBCT segmentation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 131 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jul 2024 (actual)
- Primary completion
- 1 Oct 2025 (actual)
- Study completion
- 1 Jan 2026 (actual)
- First posted
- 17 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Correlation between cervical vertebrae volume with maturational stage through CBCT
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| CBCT radiograph for Female Egyptian | – | Radiation: CBCT |
Who may qualify
- Ages
- 10 to 25 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
- Study population
- CBCT Radiographs of Egyptian Female patients
Key inclusion criteria (5 listed)
- Female patients, age range from 10-25 years .
- Patients free of any serious illness.
- Patients with no cleft lip or palate.
- Patients with no previous trauma or injury in the head and neck region.
Key exclusion criteria (1 listed)
- Patients suffering from congenital or acquired malformations affecting cervical vertebrae.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| CBCTCBCT Radiographs of Egyptian Female patients will be selected from the patients' database at the Faculty of Dentistry, Cairo University. The CBCT Radiographs data will be reconstructed using 3D imaging software (3D Slicer ). The body of the 2nd, 3rd, and 4th vertebra will be cropped and other structures will be deleted. Each vertebra will be isolated using split mask tool, then 3D format of each vertebra will be obtained, and its 3D volume in mm³ will be recorded using 3D object properties. then evaluate the association between cervical vertebrae volume and maturation stages assessed using the CVM I | Radiation | CBCT radiograph for Female Egyptian |
Primary outcome
clinical correlation between cervical vertebrae volume and patient's maturational stage
Time frame: Data is collected on Day 1 No follow up is needed because it is an observational
the data (volume of cervical vertebrae C2, C3 and C4) is collected from the CBCT of the patient on the day of arrival of the radiograph
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Jun 2026.
- Results publication: PubMed 19815136Gabriel DB, Southard KA, Qian F, Marshall SD, Franciscus RG, Southard TE. Cervical vertebrae maturation method: poor reproducibility. Am J Orthod Dentofacial Orthop. 2009 Oct;136(4):478.e1-7; discussion 478-80. doi: 10.1016/j.ajodo.2007.08.028.
- Results publication: PubMed 12169031Baccetti T, Franchi L, McNamara JA Jr. An improved version of the cervical vertebral maturation (CVM) method for the assessment of mandibular growth. Angle Orthod. 2002 Aug;72(4):316-23. doi: 10.1043/0003-3219(2002)0722.0.CO;2.
- Results publication: PubMed 10982936Franchi L, Baccetti T, McNamara JA Jr. Mandibular growth as related to cervical vertebral maturation and body height. Am J Orthod Dentofacial Orthop. 2000 Sep;118(3):335-40. doi: 10.1067/mod.2000.107009.
- Results publication: PubMed 12143094San Roman P, Palma JC, Oteo MD, Nevado E. Skeletal maturation determined by cervical vertebrae development. Eur J Orthod. 2002 Jun;24(3):303-11. doi: 10.1093/ejo/24.3.303.
- Results publication: PubMed 5218761Hunter CJ. The correlation of facial growth with body height and skeletal maturation at adolescence. Angle Orthod. 1966 Jan;36(1):44-54. doi: 10.1043/0003-3219(1966)0362.0.CO;2. No abstract available.
- Results publication: PubMed 6961802Hagg U, Taranger J. Maturation indicators and the pubertal growth spurt. Am J Orthod. 1982 Oct;82(4):299-309. doi: 10.1016/0002-9416(82)90464-x.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cervical Vertebrae, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
clinical correlation between cervical vertebrae volume and patient's maturational stage (time frame: Data is collected on Day 1 No follow up is needed because it is an observational). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07653542, which also lists 6 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Jun 2026.