CTSNCT07653789
Comparative Efficacy of Neuromobilization, Tendon Gliding Exercises, and Combined Techniques in Mild to Moderate Carpal Tunnel Syndrome
A study testing Combined Intervention Group, Neuromobilization Group and Tendon Gliding Exercise Group in people with CTS and Carpal Tunnel Syndrome (CTS), run by Ibadat International University, Islamabad at 1 site in Pakistan.
Trial summary
focuses on the comparative efficacy of Neuromobilization techniques, tendon gliding exercises, and their combined application in the management of mild to moderate Carpal Tunnel Syndrome through a randomized controlled trial (RCT) Read more about this study
- Who is it for?
- Ages 18 to 45 years
- Conditions the study is for
- CTS, Carpal Tunnel Syndrome (CTS)
- What is being tested?
- Combined Intervention Group, Neuromobilization Group and Tendon Gliding Exercise Group
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 sitePakistan
- Study dates
- 3 Jun 2026to 10 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- • Symptoms of CTS (pain, paresthesia in the area of hand innervated by the median nerve)
- First and Second Trimester Pregnant women.
- Mild to Moderate CTS patients.
- Individuals experiencing wrist pain for a duration of at least 6-8 weeks without a history of trauma or specific diagnosis (e.g., fracture, arthritis).
- Pain rated between 3 and 5 on (NPRS).
- Present neurological disorders (e.g., carpal tunnel syndrome, cervical radiculopathy).
- No prior physical therapy treatment for wrist pain in the last 3-6 months
Who cannot join
- • History of traumatic injury, fracture, or surgery to the wrist or hand.
- Diagnosis of systemic diseases affecting the wrist (e.g., rheumatoid arthritis, gout, or diabetes-related neuropathy).
- Any skin condition or infection around the wrist that would contraindicate physical therapy.
- Third Trimester Pregnant women
- Individuals with serious cardiovascular or metabolic disorders.
- patients currently undergoing other treatments specifically targeting CTS (e.g., steroid injections)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Dr. Akbar Niazi teaching Hospital
Islamabad, ICT
Gul Afsheen, DPT, MSPT MSK, +923435776966, gulafsheen123@gmail.com
About this study
Official title: Comparative Efficacy of Neuromobilization Techniques, Tendon Gliding Exercises, and Combined Techniques in the Management of Mild to Moderate Carpal Tunnel Syndrome: A Randomized Controlled Trial
focuses on the comparative efficacy of Neuromobilization techniques, tendon gliding exercises, and their combined application in the management of mild to moderate Carpal Tunnel Syndrome through a randomized controlled trial (RCT)
Read the detailed description
Aims to provide valuable evidence regarding the comparative and combined effects of Neuromobilization and tendon gliding exercises in managing mild to moderate Carpal Tunnel Syndrome. The findings may help physiotherapists develop optimized treatment strategies for improving pain, hand function, and quality of life among CTS patients.
- Conditions
- CTS, Carpal Tunnel Syndrome (CTS)
- Being tested
- Combined Intervention Group, Neuromobilization Group, Tendon Gliding Exercise Group
- Medical subject headings
- Carpal Tunnel Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Combined Intervention GroupOther
will receive a combination of Neuromobilization techniques and tendon gliding exercises
Neuromobilization GroupOther
will receive Neuromobilization techniques targeting the median nerve.
Tendon Gliding Exercise GroupOther
will receive tendon Gliding exercises targeting the median nerve
| Study group | Role | What they receive |
|---|---|---|
| Combined Intervention Group | Experimental | Participants in this group will receive a combination of Neuromobilization techniques and tendon gliding exercises Receives: Other: Combined Intervention Group |
| Neuromobilization Group | Active comparator | Participants in these groups will receive Neuromobilization techniques targeting the median nerve. Receives: Other: Neuromobilization Group |
| Tendon Gliding Exercise Group | Active comparator | will receive tendon Gliding exercises targeting the median nerve Receives: Other: Tendon Gliding Exercise Group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Intensity
Measured using the Numeric Pain Rating Scale
Measured: baseline, 3rd week, and 8th week.
Functional Status and Symptom Severity
Measured using the Boston Carpal Tunnel Questionnaire
Measured: baseline, 3rd week, and 8th week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2026
- Study start3 Jun 2026 (estimated)
- Primary completion3 Sep 2026 (estimated)
- Study completion10 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CTSStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 52 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ibadat International University, Islamabad
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07653789
- Sponsor's protocol ID
- IIUI/RERC/ADT/2026/01/221
- Status last verified
- Jun 2026
- First submitted
- 2 Jun 2026
- Last updated
- 17 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Efficacy of Neuromobilization Techniques, Tendon Gliding Exercises, and Combined Techniques in the Management of Mild to Moderate Carpal Tunnel Syndrome: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07653789
- Acronym / sponsor ID
- IIUI/RERC/ADT/2026/01/221
- Conditions
- CTS, Carpal Tunnel Syndrome (CTS)
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 52 participants (estimated)
- Lead sponsor
- Ibadat International University, IslamabadUniversity, hospital or other
- Study start
- 3 Jun 2026 (estimated)
- Primary completion
- 3 Sep 2026 (estimated)
- Study completion
- 10 Sep 2026 (estimated)
- First posted
- 17 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
focuses on the comparative efficacy of Neuromobilization techniques, tendon gliding exercises, and their combined application in the management of mild to moderate Carpal Tunnel Syndrome through a randomized controlled trial (RCT)
Detailed description
Aims to provide valuable evidence regarding the comparative and combined effects of Neuromobilization and tendon gliding exercises in managing mild to moderate Carpal Tunnel Syndrome. The findings may help physiotherapists develop optimized treatment strategies for improving pain, hand function, and quality of life among CTS patients.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Combined Intervention Group | Experimental | Other: Combined Intervention GroupParticipants in this group will receive a combination of Neuromobilization techniques and tendon gliding exercises |
| Neuromobilization Group | Active comparator | Other: Neuromobilization GroupParticipants in these groups will receive Neuromobilization techniques targeting the median nerve. |
| Tendon Gliding Exercise Group | Active comparator | Other: Tendon Gliding Exercise Groupwill receive tendon Gliding exercises targeting the median nerve |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- • Symptoms of CTS (pain, paresthesia in the area of hand innervated by the median nerve)
Key exclusion criteria (6 listed)
- • History of traumatic injury, fracture, or surgery to the wrist or hand.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Combined Intervention Groupwill receive a combination of Neuromobilization techniques and tendon gliding exercises | Other | Combined Intervention Group |
| Neuromobilization Groupwill receive Neuromobilization techniques targeting the median nerve. | Other | Neuromobilization Group |
| Tendon Gliding Exercise Groupwill receive tendon Gliding exercises targeting the median nerve | Other | Tendon Gliding Exercise Group |
Primary outcome
Pain Intensity
Time frame: baseline, 3rd week, and 8th week.
Measured using the Numeric Pain Rating Scale
Functional Status and Symptom Severity
Time frame: baseline, 3rd week, and 8th week
Measured using the Boston Carpal Tunnel Questionnaire
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Combined Intervention Group, Neuromobilization Group and Tendon Gliding Exercise Group in people with CTS and Carpal Tunnel Syndrome (CTS), run by Ibadat International University, Islamabad at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Gul Asheen, DPT, MSPT MSK (+923435776966, gulafsheen123@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Intensity (time frame: baseline, 3rd week, and 8th week.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Jun 2026; AzTrials last refreshed its copy on 6 Nov 2026.