Advanced CancerNCT07654933
Physiotherapy Effects on Function, Ambulation, and Independence in Palliative Cancer Care
A study testing Experimental: Physiotherapy Intervention Group in people with Advanced Cancer and Palliative, run by University of Jazan at 1 site in Saudi Arabia.
Trial summary
This study examines the short-term effects of physiotherapy on functional status, ambulation, and independence among patients admitted to the palliative care unit at Jazan Specialist Hospital. Read more about this study
- Who is it for?
- Ages 18 to 85 years
- Conditions the study is for
- Advanced Cancer, Palliative
- What is being tested?
- Experimental: Physiotherapy Intervention Group
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 siteSaudi Arabia
- Study dates
- 1 Aug 2025to 13 Jun 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adult patients aged 18 years or older admitted to the palliative care unit with a confirmed diagnosis of advanced cancer.
- Palliative Performance Scale (PPS) score of 40 or above.
- Clinically stable and conscious at the time of recruitment.
- Capable of providing informed consent, either personally or through a legal guardian.
Who cannot join
- 1. Pre-terminal or unstable clinical condition that precluded safe physiotherapy participation. 2. PPS score below 40 indicating severely reduced functional status.
- 3. Unconsciousness or inability to engage meaningfully in physiotherapy sessions.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Short-Term Effects of Physiotherapy on Functional Status, Ambulation, and Independence in Palliative Care Cancer Patients at Jazan Specialist Hospital: A Prospective Quasi Experimental Study
This study examines the short-term effects of physiotherapy on functional status, ambulation, and independence among patients admitted to the palliative care unit at Jazan Specialist Hospital. The study hypothesizes that a short-term individualized physiotherapy program will lead to measurable improvements in functional outcomes as assessed by the Barthel Index (BI), Functional Ambulation Category (FAC), and Palliative Performance Scale (PPS).
Read the detailed description
A prospective single-group pre-post quasi-experimental study was conducted in the Palliative Care Unit at Jazan Specialist Hospital, Jazan, Saudi Arabia, between August 2025 and April 2026. Sixty patients were managed during the study period; of these, 32 patients with complete paired pre- and post-intervention assessments were included in the final statistical analysis. Patients received an individualized physiotherapy program once daily for one week (7 sessions), with each session lasting approximately 45-60 minutes. The intervention included range-of-motion exercises, manual therapy, strengthening exercises, stretching, mobility training, transfer training, ambulation exercises, positioning, and chest physiotherapy. Outcome measures included the Barthel Index (BI), Functional Ambulation Category (FAC), and Palliative Performance Scale (PPS). Pre- and post-intervention data were analyzed using the Wilcoxon signed-rank test.
- Conditions
- Advanced Cancer, Palliative
- Being tested
- Experimental: Physiotherapy Intervention Group
- Keywords
- Palliative care, Physiotherapy, Rehabilitation, Barthel Index, Functional Ambulation Category, Palliative Performance Scale, Saudi Arabia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Experimental: Physiotherapy Intervention GroupOther
Individualized Physiotherapy Program Participants received an individualized physiotherapy program delivered once daily for one week (7 sessions), each lasting approximately 45-60 minutes. The program included: range-of-motion exercises, manual therapy, strengthening exercises, stretching, mobility training, transfer training, ambulation exercises, positioning, and chest physiotherapy, as clinically appropriate. The program was tailored to each patient's functional status, clinical condition, and tolerance, with modifications made according to daily clinical assessment. Outcome measures: Barthel Index (BI), Functional Ambulation Category (FAC), and Palliative Performance Scale (PPS) assessed at baseline (within 24-48 hours of recruitment) and after completion of the one-week intervention (day 7).
| Study group | Role | What they receive |
|---|---|---|
| Experimental: Physiotherapy Intervention Group | Other | Individualized Physiotherapy Program Participants received an individualized physiotherapy program delivered once daily for one week (7 sessions), each lasting approximately 45-60 minutes. The program included: range-of-motion exercises, manual therapy, strengthening exercises, stretching, mobility training, transfer training, ambulation exercises, positioning, and chest physiotherapy, as clinically appropriate. The program was tailored to each patient's functional status, clinical condition, and tolerance, with modifications made according to daily clinical assessment. Outcome measures: Barthel Index (BI), Functional Ambulation Category (FAC), and Palliative Performance Scale (PPS) assessed at baseline (within 24-48 hours of recruitment) and after completion of the one-week intervention (day 7). Receives: Other: Experimental: Physiotherapy Intervention Group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Improvement in Barthel Index (BI)
The BI assesses independence in activities of daily living, with higher scores indicating greater independence. Scores range from 0 to 100.
Measured: [Time Frame: Timepoint 1 = Baseline (within 24-48 hours of recruitment). Timepoint 2 = Post-intervention (day 7 or at discharge).]
Improvement in Functional Ambulation Category (FAC)
The FAC assesses walking ability and level of assistance required for ambulation. Scores range from 0 (non-ambulatory) to 5 (independent ambulation on all surfaces).
Measured: [Time Frame: Timepoint 1 = Baseline. Timepoint 2 = Post-intervention (day 7 or at discharge).]
Improvement in Palliative Performance Scale (PPS)
The PPS assesses overall functional status in palliative care, with higher scores indicating better functional performance. Scores range from 0 to 100 in increments of 10.
Measured: [Time Frame: Timepoint 1 = Baseline. Timepoint 2 = Post-intervention (day 7 or at discharge).]
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2026
- Study start1 Aug 2025
- Primary completion30 Apr 2026
- Study completion13 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Advanced CancerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 32 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Jazan
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Nujud Halawi, University of Jazan
- Investigators
- Nujud Halawi, Principal investigator, University of Jazan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07654933
- Sponsor's protocol ID
- UJazan_NHalawi
- Status last verified
- Jun 2026
- First submitted
- 12 Jun 2026
- Last updated
- 17 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Short-Term Effects of Physiotherapy on Functional Status, Ambulation, and Independence in Palliative Care Cancer Patients at Jazan Specialist Hospital: A Prospective Quasi Experimental Study
- ClinicalTrials.gov ID
- NCT07654933
- Acronym / sponsor ID
- UJazan_NHalawi
- Conditions
- Advanced Cancer, Palliative
- Keywords
- Palliative care, Physiotherapy, Rehabilitation, Barthel Index, Functional Ambulation Category, Palliative Performance Scale, Saudi Arabia
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 32 participants (actual)
- Lead sponsor
- University of JazanOther government
- Study start
- 1 Aug 2025 (actual)
- Primary completion
- 30 Apr 2026 (actual)
- Study completion
- 13 Jun 2026 (actual)
- First posted
- 17 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study examines the short-term effects of physiotherapy on functional status, ambulation, and independence among patients admitted to the palliative care unit at Jazan Specialist Hospital. The study hypothesizes that a short-term individualized physiotherapy program will lead to measurable improvements in functional outcomes as assessed by the Barthel Index (BI), Functional Ambulation Category (FAC), and Palliative Performance Scale (PPS).
Detailed description
A prospective single-group pre-post quasi-experimental study was conducted in the Palliative Care Unit at Jazan Specialist Hospital, Jazan, Saudi Arabia, between August 2025 and April 2026. Sixty patients were managed during the study period; of these, 32 patients with complete paired pre- and post-intervention assessments were included in the final statistical analysis. Patients received an individualized physiotherapy program once daily for one week (7 sessions), with each session lasting approximately 45-60 minutes. The intervention included range-of-motion exercises, manual therapy, strengthening exercises, stretching, mobility training, transfer training, ambulation exercises, positioning, and chest physiotherapy. Outcome measures included the Barthel Index (BI), Functional Ambulation Category (FAC), and Palliative Performance Scale (PPS). Pre- and post-intervention data were analyzed using the Wilcoxon signed-rank test.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Experimental: Physiotherapy Intervention Group | Other | Other: Experimental: Physiotherapy Intervention GroupIndividualized Physiotherapy Program Participants received an individualized physiotherapy program delivered once daily for one week (7 sessions), each lasting approximately 45-60 minutes. The program included: range-of-motion exercises, manual therapy, strengthening exercises, stretching, mobility training, transfer training, ambulation exercises, positioning, and chest physiotherapy, as clinically appropriate. The program was tailored to each patient's functional status, clinical condition, and tolerance, with modifications made according to daily clinical assessment. Outcome measures: Barthel Index (BI), Functional Ambulation Category (FAC), and Palliative Performance Scale (PPS) assessed at baseline (within 24-48 hours of recruitment) and after completion of the one-week intervention (day 7). |
Who may qualify
- Ages
- 18 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adult patients aged 18 years or older admitted to the palliative care unit with a confirmed diagnosis of advanced cancer.
- Palliative Performance Scale (PPS) score of 40 or above.
- Clinically stable and conscious at the time of recruitment.
- Capable of providing informed consent, either personally or through a legal guardian.
Key exclusion criteria (2 listed)
- 1. Pre-terminal or unstable clinical condition that precluded safe physiotherapy participation. 2. PPS score below 40 indicating severely reduced functional status.
- 3. Unconsciousness or inability to engage meaningfully in physiotherapy sessions.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Experimental: Physiotherapy Intervention GroupIndividualized Physiotherapy Program Participants received an individualized physiotherapy program delivered once daily for one week (7 sessions), each lasting approximately 45-60 minutes. The program included: range-of-motion exercises, manual therapy, strengthening exercises, stretching, mobility training, transfer training, ambulation exercises, positioning, and chest physiotherapy, as clinically appropriate. The program was tailored to each patient's functional status, clinical condition, and tolerance, with modifications made according to daily clinical assessment. Outcome measures: Barthel Index (BI), Functional Ambulation Category (FAC), and Palliative Performance Scale (PPS) assessed at baseline (within 24-48 hours of recruitment) and after completion of the one-week intervention (day 7). | Other | Experimental: Physiotherapy Intervention Group |
Primary outcome
Improvement in Barthel Index (BI)
Time frame: [Time Frame: Timepoint 1 = Baseline (within 24-48 hours of recruitment). Timepoint 2 = Post-intervention (day 7 or at discharge).]
The BI assesses independence in activities of daily living, with higher scores indicating greater independence. Scores range from 0 to 100.
Improvement in Functional Ambulation Category (FAC)
Time frame: [Time Frame: Timepoint 1 = Baseline. Timepoint 2 = Post-intervention (day 7 or at discharge).]
The FAC assesses walking ability and level of assistance required for ambulation. Scores range from 0 (non-ambulatory) to 5 (independent ambulation on all surfaces).
Improvement in Palliative Performance Scale (PPS)
Time frame: [Time Frame: Timepoint 1 = Baseline. Timepoint 2 = Post-intervention (day 7 or at discharge).]
The PPS assesses overall functional status in palliative care, with higher scores indicating better functional performance. Scores range from 0 to 100 in increments of 10.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Nujud Halawi principal investigator
University of Jazan
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Experimental: Physiotherapy Intervention Group in people with Advanced Cancer and Palliative, run by University of Jazan at 1 site in Saudi Arabia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Saudi Arabia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Improvement in Barthel Index (BI) (time frame: [Time Frame: Timepoint 1 = Baseline (within 24-48 hours of recruitment). Timepoint 2 = Post-intervention (day 7 or at discharge).]). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Jun 2026.