Cervical DiseaseNCT07656285
Comparison of Immediate Changes in Cervical Range of Motion Following Cervical Extension and Downslip Mobilizations.
A study testing Cervical Downslip Mobilization and Seated Cervical Extension Glide in people with Cervical Disease, run by Missouri State University at 1 site in United States.
Trial summary
The purpose of this study is to compare the efficacy seated cervical extension glides vs supine downslip glides, on both cervical rotation range of motion and patient comfort. Information gathered from this study may be used to help clinicians determine the most beneficial methods of cervical mobilizations as a… Read more about this study
- Who is it for?
- Ages 18 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Cervical Disease
- What is being tested?
- Cervical Downslip Mobilization and Seated Cervical Extension Glide
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 128 participants
- Where
- 1 siteUnited States
- Study dates
- 12 Jun 2026to 28 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- healthy individuals
- 18-45 years of age.
Who cannot join
- current or previous history of neck pain;
- cervical spine instability;
- history of cervical spine surgery;
- neurological issues;
- contraindications to mobilization including fractures, coagulation issues, and osteoporosis
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Missouri State University - Physical Therapy Clinic
Springfield, Missouri, 65810
Kim Ennis, 5176143690, kwspartan10@gmail.com
About this study
Official title: Cervical Rotation Range of Motion Improvements Following Cervical Extension vs Downslip Mobilizations
The purpose of this study is to compare the efficacy seated cervical extension glides vs supine downslip glides, on both cervical rotation range of motion and patient comfort. Information gathered from this study may be used to help clinicians determine the most beneficial methods of cervical mobilizations as a rehabilitation tool.
Read the detailed description
Subjects were randomized to either the Downslips group or the Seated AP Extension Glide. Prior to and immediately after mobilization, bilateral cervical rotation range of motion measurements were taken in seated using the Cervical Range of Motion device (CROM) which has been shown to have good validity and reliability. The starting sides of both cervical spine mobilizations were chosen at the start of data collection. After that, both therapists alternated the side to begin the mobilization with each new subject. Each mobilization was performed 5x40" with a twenty second rest between. All five mobilizations are performed first on one side, then the contralateral side in the same manner, prior to the subject returning to the seated position for retesting of their cervical rotation range of motion with the CROM. The same researcher performed the CROM measurement pre- and post-mobilization rotational testing to reduce interrater error. Following the final CROM measurement, the subject was then asked to rate their perceived comfort with the technique using a modified Visual Analogue Scale, with 0 being no pain and 10 being the most uncomfortable.
The downslip mobilization is completed in supine, with the practitioner positioned at the patient's head. The practitioner places their second metacarpophalangeal joint of the mobilization hand on the articular pillar of C2 while the stabilizing hand is on the occiput allowing for motion to occur.
Mobilization will be in an direction that is caudal and dorsal towards the subject's contralateral hip for 5x40" with a 20" rest in between. The supine downslip mobilization will be performed by the same therapist bilaterally for all subjects; this therapist has more than thirteen years of clinical experience with advanced manual therapy training. The Seated AP Extension mobilization is completed with the subject(s) seated in the Frankfort neutral position. The therapist starts by palpating the articular pillar. The stabilizing hand is placed on C3's lamina, applying a force perpendicular to a line through the oribita to block the caudal segment. The therapist's mobilizing hand will be supinated so that their lateral 5th metacarpal is on the lamina of C2. The subject is then brought into extension and rotation to the C2-3 segment and a caudal-dorsal mobilization is applied respecting the cervical spines facet joint orientation of 45 degrees for 5x40" with a 20" rest in between. The Supine AP Extension mobilization will be performed by the same therapist bilaterally for all subjects; this therapist has more than thirteen years of clinical experience with advanced manual therapy training.
- Conditions
- Cervical Disease
- Being tested
- Cervical Downslip Mobilization, Seated Cervical Extension Glide
- Medical subject headings
- Uterine Cervical Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cervical Downslip MobilizationOther
Mobilization in supine on the C2-3 articular pillar in a direction that is caudal-medial-ventral.
Seated Cervical Extension GlideOther
Mobilization of C2 on C3 in a direction that is dorsal, lateral, and caudal.
| Study group | Role | What they receive |
|---|---|---|
| Cervical Downslips | Experimental | Not described Receives: Other: Cervical Downslip Mobilization |
| Cervical Extension Glides | Experimental | Not described Receives: Other: Seated Cervical Extension Glide |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cervical Range of Motion
Measured: Immediately following mobilization
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Jun 2026
- Study start12 Jun 2026
- Primary completion28 Sep 2026 (estimated)
- Study completion28 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cervical DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 128 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Missouri State University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Kim Ennis, Missouri State University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07656285
- Sponsor's protocol ID
- IRB-FY2026-122
- Status last verified
- Jun 2026
- First submitted
- 11 Jun 2026
- Last updated
- 18 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: We will de-identify the individual participant data to share our primary outcome measurement of pre- and post-mobilization cervical range of motion.
Study at a glance
From the registry record, last updated by the sponsor on 18 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Cervical Rotation Range of Motion Improvements Following Cervical Extension vs Downslip Mobilizations
- ClinicalTrials.gov ID
- NCT07656285
- Acronym / sponsor ID
- IRB-FY2026-122
- Conditions
- Cervical Disease
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 128 participants (estimated)
- Lead sponsor
- Missouri State UniversityUniversity, hospital or other
- Study start
- 12 Jun 2026 (actual)
- Primary completion
- 28 Sep 2026 (estimated)
- Study completion
- 28 Sep 2026 (estimated)
- First posted
- 18 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to compare the efficacy seated cervical extension glides vs supine downslip glides, on both cervical rotation range of motion and patient comfort. Information gathered from this study may be used to help clinicians determine the most beneficial methods of cervical mobilizations as a rehabilitation tool.
Detailed description
Subjects were randomized to either the Downslips group or the Seated AP Extension Glide. Prior to and immediately after mobilization, bilateral cervical rotation range of motion measurements were taken in seated using the Cervical Range of Motion device (CROM) which has been shown to have good validity and reliability. The starting sides of both cervical spine mobilizations were chosen at the start of data collection. After that, both therapists alternated the side to begin the mobilization with each new subject. Each mobilization was performed 5x40" with a twenty second rest between. All five mobilizations are performed first on one side, then the contralateral side in the same manner, prior to the subject returning to the seated position for retesting of their cervical rotation range of motion with the CROM. The same researcher performed the CROM measurement pre- and post-mobilization rotational testing to reduce interrater error. Following the final CROM measurement, the subject was then asked to rate their perceived comfort with the technique using a modified Visual Analogue Scale, with 0 being no pain and 10 being the most uncomfortable.
The downslip mobilization is completed in supine, with the practitioner positioned at the patient's head. The practitioner places their second metacarpophalangeal joint of the mobilization hand on the articular pillar of C2 while the stabilizing hand is on the occiput allowing for motion to occur.
Mobilization will be in an direction that is caudal and dorsal towards the subject's contralateral hip for 5x40" with a 20" rest in between. The supine downslip mobilization will be performed by the same therapist bilaterally for all subjects; this therapist has more than thirteen years of clinical experience with advanced manual therapy training. The Seated AP Extension mobilization is completed with the subject(s) seated in the Frankfort neutral position. The therapist starts by palpating the articular pillar. The stabilizing hand is placed on C3's lamina, applying a force perpendicular to a line through the oribita to block the caudal segment. The therapist's mobilizing hand will be supinated so that their lateral 5th metacarpal is on the lamina of C2. The subject is then brought into extension and rotation to the C2-3 segment and a caudal-dorsal mobilization is applied respecting the cervical spines facet joint orientation of 45 degrees for 5x40" with a 20" rest in between. The Supine AP Extension mobilization will be performed by the same therapist bilaterally for all subjects; this therapist has more than thirteen years of clinical experience with advanced manual therapy training.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Cervical Downslips | Experimental | Other: Cervical Downslip Mobilization |
| Cervical Extension Glides | Experimental | Other: Seated Cervical Extension Glide |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- healthy individuals
- 18-45 years of age.
Key exclusion criteria (5 listed)
- current or previous history of neck pain;
- cervical spine instability;
- history of cervical spine surgery;
- neurological issues;
- contraindications to mobilization including fractures, coagulation issues, and osteoporosis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cervical Downslip MobilizationMobilization in supine on the C2-3 articular pillar in a direction that is caudal-medial-ventral. | Other | Cervical Downslips |
| Seated Cervical Extension GlideMobilization of C2 on C3 in a direction that is dorsal, lateral, and caudal. | Other | Cervical Extension Glides |
Primary outcome
Cervical Range of Motion
Time frame: Immediately following mobilization
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Jun 2026.
- Individual participant dataSharing planned: Yes. We will de-identify the individual participant data to share our primary outcome measurement of pre- and post-mobilization cervical range of motion.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cervical Downslip Mobilization and Seated Cervical Extension Glide in people with Cervical Disease, run by Missouri State University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 18 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Kim Ennis, PT, ScD, OCS, FAAOMPT (15176143690, kwspartan10@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cervical Range of Motion (time frame: Immediately following mobilization). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jun 2026.