Myocardial IschemiaNCT07657546
MCG for Non-Obstructive Myocardial Ischemia
An observational study of Myocardial Ischemia, run by Qilu Hospital of Shandong University at 1 site in China.
Trial summary
The aim of this prospective study is to identify Non-Obstructive Myocardial Ischemia of patients who have acute chest pain using Magnetocardiography. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Myocardial Ischemia
- What is being tested?
- Magnetocardiography
- Type of treatment
- Medical device
- How many people
- 3,786 participants
- Where
- 1 siteChina
- Study dates
- 15 Apr 2025to 30 Aug 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: patient who suffers from cardiogenic chest pain suspected with Non-Obstructive Myocardial Ischemia
Who may be able to join
- Age 18 years or older;
- Patients with symptoms of myocardial ischemia such as angina pectoris, who have CAG showing <70% stenosis at the most severe site or CTA showing non-severe stenosis
- Signed informed consent.
Who cannot join
- Patients with absolute or relative contraindications to CFR-loaded myocardial perfusion, including acute myocardial infarction within 48 hours, significant left main coronary artery stenosis, bronchial asthma, and adenosine injection allergy;
- Patients with Non-ischemic dilated cardiomyopathy, or hypertrophic cardiomyopathy, or moderate or severe valvular disease;
- Patients with Hemodynamic instability (systolic blood pressure<90 mmHg, or who requires vasoactive drugs), or patients with tachyarrhythmia,
- #degree atrioventricular block and above that have not returned to normal;
- Patients who have severe renal abnormality with eGFR <30 ml/min, or patients who are on dialysis;
- Patients with malignant tumors with predicted survival of less than 1 year;
- Pregnant or breastfeeding women;
- Patients who are unable to enter the MCG device, who are unable to perform MCG examination due to interference from metal implants or other reasons, or who are deemed by the investigators to be unsuitable for enrollment.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
Qliu Hospital of Shandong University
Jinan, Shandong, 250012
Jiaojiao Pang, Doctor, 0086-0531-82165398, jiaojiaopang@126.com
Chen
About this study
Official title: Magnetocardiography in the Identification of Non-Obstructive Myocardial Ischemia of Patients With Acute Chest Pain
The aim of this prospective study is to identify Non-Obstructive Myocardial Ischemia of patients who have acute chest pain using Magnetocardiography.
- Conditions
- Myocardial Ischemia
- Being tested
- Magnetocardiography
- Keywords
- Ischemia with No Obstructive Coronary Arteries
- Medical subject headings
- Myocardial Ischemia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
MagnetocardiographyDevice
Assessing the performance of magnetocardiography device for detecting non-obstructive myocardial ischemia using ultrasound coronary flow reserve (CFR) as the reference standard.
What is being measured
The primary outcome is the main question the study is designed to answer.
Efficacy of MCG for the detection of Non-Obstructive Myocardial Ischemia
Establishing an algorithm model of MCG in identifying Non-Obstructive Myocardial Ischemia, the efficacy of the model was assessed by sensitivity, specificity
Measured: from the date of enrollment until the date of discharge, up to 30 days]
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Jun 2026
- Study start15 Apr 2025
- Primary completion30 Jun 2026 (estimated)
- Study completion30 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Myocardial IschemiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 3,786 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Qilu Hospital of Shandong University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Yuguo Chen, Professor, Principal investigator, Qliu Hospital of Shandong University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07657546
- Sponsor's protocol ID
- MCG-CFR
- Status last verified
- Jun 2026
- First submitted
- 14 Jun 2026
- Last updated
- 24 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Magnetocardiography in the Identification of Non-Obstructive Myocardial Ischemia of Patients With Acute Chest Pain
- ClinicalTrials.gov ID
- NCT07657546
- Acronym / sponsor ID
- MCG-CFR
- Conditions
- Myocardial Ischemia
- Keywords
- Ischemia with No Obstructive Coronary Arteries
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 3,786 participants (estimated)
- Lead sponsor
- Qilu Hospital of Shandong UniversityUniversity, hospital or other
- Study start
- 15 Apr 2025 (actual)
- Primary completion
- 30 Jun 2026 (estimated)
- Study completion
- 30 Aug 2026 (estimated)
- First posted
- 18 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this prospective study is to identify Non-Obstructive Myocardial Ischemia of patients who have acute chest pain using Magnetocardiography.
Study design
- Observational model
- Other
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- patient who suffers from cardiogenic chest pain suspected with Non-Obstructive Myocardial Ischemia
Key inclusion criteria (3 listed)
- Age 18 years or older;
- Patients with symptoms of myocardial ischemia such as angina pectoris, who have CAG showing <70% stenosis at the most severe site or CTA showing non-severe stenosis
- Signed informed consent.
Key exclusion criteria (8 listed)
- Patients with absolute or relative contraindications to CFR-loaded myocardial perfusion, including acute myocardial infarction within 48 hours, significant left main coronary artery stenosis, bronchial asthma, and adenosine injection allergy;
- Patients with Non-ischemic dilated cardiomyopathy, or hypertrophic cardiomyopathy, or moderate or severe valvular disease;
- Patients with Hemodynamic instability (systolic blood pressure<90 mmHg, or who requires vasoactive drugs), or patients with tachyarrhythmia,
- #degree atrioventricular block and above that have not returned to normal;
- Patients who have severe renal abnormality with eGFR <30 ml/min, or patients who are on dialysis;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| MagnetocardiographyAssessing the performance of magnetocardiography device for detecting non-obstructive myocardial ischemia using ultrasound coronary flow reserve (CFR) as the reference standard. | Device | – |
Primary outcome
Efficacy of MCG for the detection of Non-Obstructive Myocardial Ischemia
Time frame: from the date of enrollment until the date of discharge, up to 30 days]
Establishing an algorithm model of MCG in identifying Non-Obstructive Myocardial Ischemia, the efficacy of the model was assessed by sensitivity, specificity
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Yuguo Chen, Professor principal investigator
Qliu Hospital of Shandong University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Myocardial Ischemia, run by Qilu Hospital of Shandong University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 24 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Jiaojiao Pang, Doctor (0086-0531-82165398, jiaojiaopang@126.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Efficacy of MCG for the detection of Non-Obstructive Myocardial Ischemia (time frame: from the date of enrollment until the date of discharge, up to 30 days]). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jun 2026.