Non Sarcopenic SubjectsOSSFNCT07658625
Association Between Oral Hypofunction, Sarcopenia and Social Frailty in Community-dwelling Older Adults
An observational study of Non Sarcopenic Subjects and Possible Sarcopenia, run by Chang Gung University of Science and Technology at 1 site in Taiwan.
Trial summary
Previous studies have provided a preliminary understanding of the likelihood of sarcopenia and the prevalence of sarcopenia in the elderly in the community. due to the interaction between physiological and social factors, this study aims to conduct a correlation study on muscle mass, oral function and social frailty… Read more about this study
- Who is it for?
- Ages 65 years and olderHealthy volunteers can take part
- Conditions the study is for
- Non Sarcopenic Subjects, Possible Sarcopenia, Sarcopenia(With Low ASM by BIM)
- What is being tested?
- Non interventional study
- How many people
- 200 participants
- Where
- 1 siteTaiwan
- Study dates
- 14 Nov 2025to 4 Jun 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- Healthy volunteers accepted
- Older adult
Study population: Care centers in Taoyuan City and various districts of New Taipei City
Group A-Inclusion Criteria:
- 65 years old or above
- general public or institutionalized for 3 months or more
- those who accept the experimental design and are willing to sign the consent form
- dietary sources are oral intake
- those who are diagnosed as having possible sarcopenia by researchers
Group B-Inclusion Criteria:
- 65 years old or above
- general public or institutionalized for 3 months or more
- those who accept the experimental design and are willing to sign the consent form
- dietary sources are oral intake
- those who were determined by researchers to be non-probable sarcopenia
Group A、B-Exclusion Criteria:
- comorbidities, critical illness, pre- and post-major surgery, cancer, renal failure, liver failure, kidney disease, liver disease, malignant tumors within the past five years, inflammatory conditions (c-reactive protein >10mg/dL)
- severely malnourished people
- long-term force-feeding
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Association Between Oral Hypofunction, Sarcopenia, and Social Frailty in Community-Dwelling Older Adults
Previous studies have provided a preliminary understanding of the likelihood of sarcopenia and the prevalence of sarcopenia in the elderly in the community. due to the interaction between physiological and social factors, this study aims to conduct a correlation study on muscle mass, oral function and social frailty in the elderly living in the community.
This study，the Makizako social frailty screening index questionnaire and the Tilburg Frailty Indicator will be used to assess the social frailty status of the study participants. Correlation analysis with sarcopenia and oral dysfunction was also conducted to better understand the interaction between nutrition, physiology, and social connection in the elderly, which will be helpful for formulating relevant policies and promoting healthy aging in the future in extremely elderly countries.
- Being tested
- Non interventional study
- Keywords
- Sarcopenia, Poor oral function, Social weakness, chew, Nutrition
- Medical subject headings
- Sarcopenia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Non interventional studyOther
NON
| Study group | Role | What they receive |
|---|---|---|
| Group A | Possible sarcopenia Receives: Other: Non interventional study | |
| Group B | Non-possible sarcopenia Receives: Other: Non interventional study |
What is being measured
The primary outcome is the main question the study is designed to answer.
Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.
- The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women
- 6-meter walking speed less than 1.0 second/meter
- 5-time chair stand test greater than or equal to 12 seconds
- Short physical performance battery, SPPB greater than or equal to 9 points The above will be combined to determine whether sarcopenia is possible.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jun 2026
- Study start14 Nov 2025
- Primary completion4 Jun 2026
- Study completion4 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Non Sarcopenic SubjectsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 200 participants (actual)
Sponsor and investigators
- Lead sponsor
- Chang Gung University of Science and Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07658625
- Sponsor's protocol ID
- 202500861A3
- Other IDs
- ZRRPF3Q0061
- Acronym
- OSSF
- Status last verified
- Jun 2026
- First submitted
- 10 Jun 2026
- Last updated
- 22 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Association Between Oral Hypofunction, Sarcopenia, and Social Frailty in Community-Dwelling Older Adults
- ClinicalTrials.gov ID
- NCT07658625
- Acronym / sponsor ID
- OSSF / 202500861A3
- Keywords
- Sarcopenia, Poor oral function, Social weakness, chew, Nutrition
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 200 participants (actual)
- Lead sponsor
- Chang Gung University of Science and TechnologyUniversity, hospital or other
- Study start
- 14 Nov 2025 (actual)
- Primary completion
- 4 Jun 2026 (actual)
- Study completion
- 4 Jun 2026 (actual)
- First posted
- 22 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Previous studies have provided a preliminary understanding of the likelihood of sarcopenia and the prevalence of sarcopenia in the elderly in the community. due to the interaction between physiological and social factors, this study aims to conduct a correlation study on muscle mass, oral function and social frailty in the elderly living in the community.
This study，the Makizako social frailty screening index questionnaire and the Tilburg Frailty Indicator will be used to assess the social frailty status of the study participants. Correlation analysis with sarcopenia and oral dysfunction was also conducted to better understand the interaction between nutrition, physiology, and social connection in the elderly, which will be helpful for formulating relevant policies and promoting healthy aging in the future in extremely elderly countries.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A | – | Other: Non interventional studyPossible sarcopenia |
| Group B | – | Other: Non interventional studyNon-possible sarcopenia |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
- Study population
- Care centers in Taoyuan City and various districts of New Taipei City
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Non interventional studyNON | Other | Group A, Group B |
Primary outcome
Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.
Time frame: Baseline
* The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women * 6-meter walking speed less than 1.0 second/meter * 5-time chair stand test greater than or equal to 12 seconds * Short physical performance battery, SPPB greater than or equal to 9 points The above will be combined to determine whether sarcopenia is possible.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jun 2026.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Non Sarcopenic Subjects and Possible Sarcopenia, run by Chang Gung University of Science and Technology at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established. (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jun 2026.