Breast CancerNCT07662629
Addtional Effect of Hyperbaric Oxygen to Programmed Physical Activity on Musckoloskeletal Pain in Breast Cancer Elderly
A study testing hyperbaric therapy and exercise and exercise in people with Breast Cancer, run by Cairo University at 1 site in Egypt.
Trial summary
patienst who survived from breast cancer are prescribed long administraion of aromatase inhbitors.. these inhibitors usually induce musckloskeletal pains. Programmed phsyical activity are reommended to improve these pains but effects of HYperbaric oxygen on these pain was not investigated Read more about this study
- Who is it for?
- Ages 65 to 75 years, women only
- Conditions the study is for
- Breast Cancer
- What is being tested?
- hyperbaric therapy and exercise and exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 7 May 2026to 1 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 75 years
- Women only
- No healthy volunteers
- Older adult
Who may be able to join
- braest cancer survivors
- patients receiving aramatase inhibitor drugs
- patients with musckolskeletal pains
Who cannot join
- cardiac patients
- respiratory patients
- renal patients
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Cairo University
Dokki, Giza Governorate, 11432
ali AM Ismail, lecturer, +201005154209, ali.mohamed@pt.cu.edu.eg
About this study
Official title: Addtion of Hyperbaric Oxygen to Programmed Physical Activity in Aromatse Inhibtors-linked Musckoloskeletal Pain in Breast Cancer Patients
patienst who survived from breast cancer are prescribed long administraion of aromatase inhbitors.. these inhibitors usually induce musckloskeletal pains. Programmed phsyical activity are reommended to improve these pains but effects of HYperbaric oxygen on these pain was not investigated
Read the detailed description
forty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake were assigned to two groups, group I and group II. the groups received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) but group II additinally received one-hour hyperbaric therapy session , five times weekly for 2 month.
- Conditions
- Breast Cancer
- Being tested
- hyperbaric therapy and exercise, exercise
- Medical subject headings
- Breast Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
hyperbaric therapy and exerciseOther
Twenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) and additinally received one-hour hyperbaric therapy session , five times weekly for 2 month.
exerciseOther
Twenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly for 2 month).
| Study group | Role | What they receive |
|---|---|---|
| group number 1 | Experimental | Twenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) and additinally received one-hour hyperbaric therapy session , five times weekly for 2 month. Receives: Other: hyperbaric therapy and exercise |
| group number 2 | Active comparator | Twenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) Receives: Other: exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
visual analogue scale
it self asessmant of pain level
Measured: it will be measured after 2 months
Secondary outcomes (10)
worst pain
it is a subscore of brief pain inventory
Measured: it will be measured after 2 months
pain severity
it is a subscore of brief pain inventory
Measured: it will be measured after 2 months
pain related interference
it is a subscore of brief pain inventory
Measured: it will be measured after 2 months
pain score
it is a sub score of Western Ontario and McMaster Universities Osteoarthritis
Measured: it will be measured after 2 months
stifness score
it is a sub score of Western Ontario and McMaster Universities Osteoarthritis
Measured: it will be measured after 2 months
fucntion score
it is a sub score of Western Ontario and McMaster Universities Osteoarthritis
Measured: it will be measured after 2 months
total score of Western Ontario and McMaster Universities Osteoarthritis
it is usualy used in patients with arthritic pains
Measured: it will be measured after 2 months
Disabilities of the Arm, Shoulder and Hand questionnaire
the short form of it used in patients with arthritic pains
Measured: it will be measured after 2 months
fatigue severity scale
it is used to assess fatigue
Measured: it will be measured after 2 months
Short Physical Performance Battery
total score used to assess physical performance
Measured: it will be measured after 2 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jun 2026
- Study start7 May 2026
- Primary completion1 Sep 2026 (estimated)
- Study completion1 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Breast CancerStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ali Mohamed Ali ismail, Cairo University
- Investigators
- Ali MA Ismail, lecturer, Principal investigator, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07662629
- Sponsor's protocol ID
- IRB000-14233-82
- Status last verified
- Jun 2026
- First submitted
- 17 Jun 2026
- Last updated
- 23 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Addtion of Hyperbaric Oxygen to Programmed Physical Activity in Aromatse Inhibtors-linked Musckoloskeletal Pain in Breast Cancer Patients
- ClinicalTrials.gov ID
- NCT07662629
- Acronym / sponsor ID
- IRB000-14233-82
- Conditions
- Breast Cancer
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 7 May 2026 (actual)
- Primary completion
- 1 Sep 2026 (estimated)
- Study completion
- 1 Sep 2026 (estimated)
- First posted
- 23 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
patienst who survived from breast cancer are prescribed long administraion of aromatase inhbitors.. these inhibitors usually induce musckloskeletal pains. Programmed phsyical activity are reommended to improve these pains but effects of HYperbaric oxygen on these pain was not investigated
Detailed description
forty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake were assigned to two groups, group I and group II. the groups received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) but group II additinally received one-hour hyperbaric therapy session , five times weekly for 2 month.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| group number 1 | Experimental | Other: hyperbaric therapy and exerciseTwenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) and additinally received one-hour hyperbaric therapy session , five times weekly for 2 month. |
| group number 2 | Active comparator | Other: exerciseTwenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) |
Who may qualify
- Ages
- 65 to 75 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
Key inclusion criteria (3 listed)
- braest cancer survivors
- patients receiving aramatase inhibitor drugs
- patients with musckolskeletal pains
Key exclusion criteria (3 listed)
- cardiac patients
- respiratory patients
- renal patients
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| hyperbaric therapy and exerciseTwenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) and additinally received one-hour hyperbaric therapy session , five times weekly for 2 month. | Other | group number 1 |
| exerciseTwenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly for 2 month). | Other | group number 2 |
Primary outcome
visual analogue scale
Time frame: it will be measured after 2 months
it self asessmant of pain level
10 secondary outcomes
worst pain
Time frame: it will be measured after 2 months
pain severity
Time frame: it will be measured after 2 months
pain related interference
Time frame: it will be measured after 2 months
pain score
Time frame: it will be measured after 2 months
stifness score
Time frame: it will be measured after 2 months
fucntion score
Time frame: it will be measured after 2 months
total score of Western Ontario and McMaster Universities Osteoarthritis
Time frame: it will be measured after 2 months
Disabilities of the Arm, Shoulder and Hand questionnaire
Time frame: it will be measured after 2 months
fatigue severity scale
Time frame: it will be measured after 2 months
Short Physical Performance Battery
Time frame: it will be measured after 2 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Ali MA Ismail, lecturer principal investigator
Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing hyperbaric therapy and exercise and exercise in people with Breast Cancer, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 23 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ali MA Ismail, lecturer (01005154209, ali.mohamed@pt.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
visual analogue scale (time frame: it will be measured after 2 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jun 2026.