Nasal PackingNCT07663929
Nasal Packing After Turbinoplasty
A study testing Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplasty, A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplasty and Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplasty in people with Nasal Packing, run by Kafrelsheikh University at 1 site in Egypt.
Trial summary
This study aims to to compare postoperative pain, patient comfort, and hemostatic safety among four non-absorbable nasal packing techniques following microdebrider-assisted inferior turbinoplasty (MAIT) and to identify the most effective low-cost packing option. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Nasal Packing
- What is being tested?
- Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplasty, A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplasty and Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplasty
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 135 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2026to 3 Jun 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults aged 18-65 years.
- Chronic bilateral nasal obstruction secondary to inferior turbinate hypertrophy.
- Failure of conservative medical management for at least 3 months, including intranasal corticosteroids and oral antihistamines.
- Positive decongestion test showing ≥30% improvement in anterior nasal cavity volume (V2-5 cm) on acoustic rhinometry after topical xylometazoline 0.5%, confirming predominantly mucosal rather than bony hypertrophy.
- Inferior turbinate hypertrophy grade 3 or 4 according to the Camacho classification system.
Who cannot join
- Significant nasal septal deviation affecting the nasal valve region.
- Internal or external nasal valve collapse or stenosis.
- Chronic rhinosinusitis with or without nasal polyposis.
- Previous nasal or paranasal sinus surgery.
- Coagulopathy or current anticoagulant therapy.
- Uncontrolled systemic disease.
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- Pregnancy.
- Active smoking.
- Known allergic sensitization to any component of the nasal packing materials.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Nasal Packing After Turbinoplasty, Is it Worthwhile? A Prospective Study ?
This study aims to to compare postoperative pain, patient comfort, and hemostatic safety among four non-absorbable nasal packing techniques following microdebrider-assisted inferior turbinoplasty (MAIT) and to identify the most effective low-cost packing option.
- Conditions
- Nasal Packing
- Being tested
- Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplasty, A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplasty, Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplasty, terile ribbon gauze impregnated with white petroleum jelly (paraffin) after microdebrider-assisted inferior turbinoplasty
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplastyProcedure or surgery
Standard bilateral Merocel® nasal tampons (Medtronic, USA) were inserted in their dry compressed form. Prior to insertion, each tampon was trimmed according to the dimensions of the patient's nasal cavity. Following contact with nasal secretions, the Merocel expanded to provide gentle and uniform pressure over the operative site.
A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplastyProcedure or surgery
A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove. The glove finger was then partially stripped to expose portions of the Merocel surface while retaining a thin latex interface, thereby preventing the glove from acting as a complete barrier and allowing contact between the Merocel and surrounding nasal secretions. This modification preserved the expansion and absorptive properties of the Merocel while creating a smoother, less adherent outer surface.
Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplastyProcedure or surgery
Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment, such as fusidic acid 2% plus corticosteroids, prior to bilateral insertion. This modification was intended to provide localized antimicrobial coverage while preserving the hemostatic effect of the packing material.
terile ribbon gauze impregnated with white petroleum jelly (paraffin) after microdebrider-assisted inferior turbinoplastyProcedure or surgery
Sterile ribbon gauze impregnated with white petroleum jelly (paraffin) was loosely packed into each nasal cavity in a layered accordion-like fashion, beginning at the nasal floor and progressing posteriorly. Packing density was standardized to achieve adequate hemostasis while avoiding excessive pressure on the nasal mucosa.
| Study group | Role | What they receive |
|---|---|---|
| Standard bilateral Merocel® nasal tampons | Active comparator | Not described Receives: Procedure: Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplasty |
| A Merocel® tampon enclosed within the finger portion of a sterile powder-free latex surgical glove | Active comparator | Not described Receives: Procedure: A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplasty |
| Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment | Active comparator | Not described Receives: Procedure: Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplasty |
| sterile ribbon gauze impregnated with white petroleum jelly (paraffin) | Active comparator | Not described Receives: Procedure: terile ribbon gauze impregnated with white petroleum jelly (paraffin) after microdebrider-assisted inferior turbinoplasty |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain intensity
1.Pain intensity Assessed using the Visual Analogue Scale (VAS) (0 = no pain, 10 = worst imaginable pain)
Measured: We assesed pain during first 48 hours postoperative.
Bleeding after packing removal Assessed using a 4-point grading scale
Grade 0 = no bleeding Grade 1 = oozing Grade 2 = continuous bleeding Grade 3 = bleeding requiring intervention or control in the operating room
Measured: We assesed bleeding immediately after nasal packing removal
Secondary outcomes (1)
Nasal fullness/pressure sensation
Nasal fullness/pressure sensation Assessed using the Visual Analogue Scale (VAS; 0-10)
Measured: We assesed it during first 48 hours postoperative.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jun 2026
- Study start1 Jan 2026
- Primary completion6 May 2026
- Study completion3 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Nasal PackingStudies of the same condition, open and under way.
- More trials run by Kafrelsheikh UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 135 participants (actual)
Sponsor and investigators
- Lead sponsor
- Kafrelsheikh University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Magdi Noaman Othman Orabi, Kafrelsheikh University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07663929
- Sponsor's protocol ID
- KFSIRB200-1082
- Status last verified
- Jan 2026
- First submitted
- 14 Jun 2026
- Last updated
- 23 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 23 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Nasal Packing After Turbinoplasty, Is it Worthwhile? A Prospective Study ?
- ClinicalTrials.gov ID
- NCT07663929
- Acronym / sponsor ID
- KFSIRB200-1082
- Conditions
- Nasal Packing
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 135 participants (actual)
- Lead sponsor
- Kafrelsheikh UniversityUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 6 May 2026 (actual)
- Study completion
- 3 Jun 2026 (actual)
- First posted
- 23 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to to compare postoperative pain, patient comfort, and hemostatic safety among four non-absorbable nasal packing techniques following microdebrider-assisted inferior turbinoplasty (MAIT) and to identify the most effective low-cost packing option.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Standard bilateral Merocel® nasal tampons | Active comparator | Procedure: Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplasty |
| A Merocel® tampon enclosed within the finger portion of a sterile powder-free latex surgical glove | Active comparator | Procedure: A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplasty |
| Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment | Active comparator | Procedure: Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplasty |
| sterile ribbon gauze impregnated with white petroleum jelly (paraffin) | Active comparator | Procedure: terile ribbon gauze impregnated with white petroleum jelly (paraffin) after microdebrider-assisted inferior turbinoplasty |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Adults aged 18-65 years.
- Chronic bilateral nasal obstruction secondary to inferior turbinate hypertrophy.
- Failure of conservative medical management for at least 3 months, including intranasal corticosteroids and oral antihistamines.
- Positive decongestion test showing ≥30% improvement in anterior nasal cavity volume (V2-5 cm) on acoustic rhinometry after topical xylometazoline 0.5%, confirming predominantly mucosal rather than bony hypertrophy.
- Inferior turbinate hypertrophy grade 3 or 4 according to the Camacho classification system.
Key exclusion criteria (9 listed)
- Significant nasal septal deviation affecting the nasal valve region.
- Internal or external nasal valve collapse or stenosis.
- Chronic rhinosinusitis with or without nasal polyposis.
- Previous nasal or paranasal sinus surgery.
- Coagulopathy or current anticoagulant therapy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplastyStandard bilateral Merocel® nasal tampons (Medtronic, USA) were inserted in their dry compressed form. Prior to insertion, each tampon was trimmed according to the dimensions of the patient's nasal cavity. Following contact with nasal secretions, the Merocel expanded to provide gentle and uniform pressure over the operative site. | Procedure or surgery | Standard bilateral Merocel® nasal tampons |
| A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplastyA Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove. The glove finger was then partially stripped to expose portions of the Merocel surface while retaining a thin latex interface, thereby preventing the glove from acting as a complete barrier and allowing contact between the Merocel and surrounding nasal secretions. This modification preserved the expansion and absorptive properties of the Merocel while creating a smoother, less adherent outer surface. | Procedure or surgery | A Merocel® tampon enclosed within the finger portion of a sterile powder-free latex surgical glove |
| Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplastyMerocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment, such as fusidic acid 2% plus corticosteroids, prior to bilateral insertion. This modification was intended to provide localized antimicrobial coverage while preserving the hemostatic effect of the packing material. | Procedure or surgery | Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment |
| terile ribbon gauze impregnated with white petroleum jelly (paraffin) after microdebrider-assisted inferior turbinoplastySterile ribbon gauze impregnated with white petroleum jelly (paraffin) was loosely packed into each nasal cavity in a layered accordion-like fashion, beginning at the nasal floor and progressing posteriorly. Packing density was standardized to achieve adequate hemostasis while avoiding excessive pressure on the nasal mucosa. | Procedure or surgery | sterile ribbon gauze impregnated with white petroleum jelly (paraffin) |
Primary outcome
Pain intensity
Time frame: We assesed pain during first 48 hours postoperative.
1.Pain intensity Assessed using the Visual Analogue Scale (VAS) (0 = no pain, 10 = worst imaginable pain)
Bleeding after packing removal Assessed using a 4-point grading scale
Time frame: We assesed bleeding immediately after nasal packing removal
Grade 0 = no bleeding Grade 1 = oozing Grade 2 = continuous bleeding Grade 3 = bleeding requiring intervention or control in the operating room
1 secondary outcome
Nasal fullness/pressure sensation
Time frame: We assesed it during first 48 hours postoperative.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jun 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplasty, A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplasty and Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplasty in people with Nasal Packing, run by Kafrelsheikh University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain intensity (time frame: We assesed pain during first 48 hours postoperative.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jun 2026; AzTrials last refreshed its copy on 2 Nov 2026.