Safe Intravenous Therapy Practices in Nursing StudentsIV:IntravenousNCT07669311
Puzzle-Assisted Learning IV: Information Retention and Motivation
An observational study of Safe Intravenous Therapy Practices in Nursing Students, run by Aydin Adnan Menderes University at 1 site in Turkey (Türkiye).
Trial summary
This study aims to evaluate the effect of puzzle-based education on nursing students' knowledge level, knowledge retention, and learning motivation regarding safe intravenous therapy practices. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Safe Intravenous Therapy Practices in Nursing Students
- What is being tested?
- Puzzle-based intravenous therapy education
- Type of treatment
- Injection or infusion, Lifestyle or therapy programme
- How many people
- 81 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 19 Nov 2025to 8 Jan 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The target population of the study consists of third-year students enrolled in the Department of Nursing, Faculty of Nursing, Aydın Adnan Menderes University (N = 290). The study sample is planned to include third-year nursing students registered in the Safe Medication Practices course during the Fall semester of the 2025-2026 academic year at Aydın Adnan Menderes University, Faculty of Nursing.
Who may be able to join
- Be a 3rd-year undergraduate nursing student
- Fully participate in the Safe Intravenous Therapy Practices training
- Be willing to participate in the study
Who cannot join
- Being unable to regularly attend the training sessions due to academic leave, health problems, or personal reasons
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Aydın Adnan Menderes University, Faculty of Nursing
Aydin, Efeler, 09020
About this study
Official title: The Effect of Puzzle-Based Safe Intravenous Therapy Applications on Students' Knowledge Level, Knowledge Retention, and Learning Motivation: A Randomized Controlled Study
This study aims to evaluate the effect of puzzle-based education on nursing students' knowledge level, knowledge retention, and learning motivation regarding safe intravenous therapy practices. Intravenous therapy is a common but complex clinical procedure that requires accurate knowledge and skills to ensure patient safety. Traditional teaching methods may not always be sufficient to support long-term learning and student motivation. Therefore, this study uses an interactive, game-based learning approach by integrating puzzles into the education process. Nursing students are randomly assigned to either a puzzle-based learning group or a traditional education group. The study seeks to determine whether game-based learning improves learning outcomes compared to conventional teaching methods.
- Being tested
- Puzzle-based intravenous therapy education
- Keywords
- Nursing education Intravenous therapy, Game-based learning, Patient safety
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Puzzle-based intravenous therapy educationBehavioural
This intervention uses puzzle-based learning activities to teach safe intravenous therapy practices to nursing students. The puzzles are designed to reinforce knowledge, improve retention, and increase motivation compared to traditional teaching methods.
| Study group | Role | What they receive |
|---|---|---|
| Traditional education group | Not described | |
| Puzzle-based education group | Not described Receives: Behavioral: Puzzle-based intravenous therapy education |
What is being measured
The primary outcome is the main question the study is designed to answer.
Intravenous Therapy Knowledge Score
Knowledge regarding safe intravenous therapy practices assessed using a researcher-developed multiple-choice questionnaire. Higher scores indicate better knowledge.
Measured: Baseline, 1 week after completion of the intervention, and 4 weeks after completion of the intervention
Learning Motivation Score
Learning motivation assessed using the Instructional Materials Motivation Survey (IMMS) and the Instructional Materials Motivation Scale (IMMS-SU). Higher scores indicate greater learning motivation.
Measured: 1 week after completion of the intervention
Secondary outcomes (1)
Knowledge Retention Score
Retention of knowledge regarding safe intravenous therapy practices assessed using the researcher-developed questionnaire. Higher scores indicate better knowledge retention.
Measured: 4 weeks after completion of the intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Jun 2026
- Study start19 Nov 2025
- Primary completion8 Jan 2026
- Study completion8 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Safe Intravenous Therapy Practices in Nursing StudentsStudies of the same condition, open and under way.
- More trials run by Aydin Adnan Menderes UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 81 participants (actual)
Sponsor and investigators
- Lead sponsor
- Aydin Adnan Menderes University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yıldız DENAT, Aydin Adnan Menderes University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07669311
- Sponsor's protocol ID
- ADU-SBE-GK-01
- Acronym
- IV:Intravenous
- Status last verified
- May 2026
- First submitted
- 16 Jun 2026
- Last updated
- 25 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Kalkan, N., Güler, S., Bulut, H., & Ay, A. (2022). Views of students on the use of crossword and word search puzzle as a teaching technique in nursing education: A mixed-method study. Nurse Education Today, 113, 105542. https://doi.org/10.1016/j.nedt.2022.105542 Shawahna, R., & Jaber, M. (2020). Crossword puzzles improve learning of Palestinian nursing students about pharmacology of epilepsy: Results of a randomized controlled study. Nurse Education Today, 108, 107024. https://doi.org/10.1016/j.yebeh.2020.107024 Alexandrou, E., et al. (2018). Use of short peripheral intravenous catheters: Characteristics, management, and outcomes worldwide. Journal of Hospital Medicine, 22(30), 1-7. https://doi.org/10.12788/jhm.3039 Ergin Doğan, S., & Aslan, H. (2024). Hemşirelik eğitiminde kullanılan güncel öğretim yöntem ve teknikleri. Bingöl Üniversitesi Sağlık Dergisi, 5(1), 224-235. https://doi.org/10.58605/bingolsaglik.1448021 Tosun, Ö., İ. K., & Doğan, S. D. (2023). The effect of crossword puzzles on nursing students' learning of concepts related to pain management course: A randomized controlled trial. Nurse Education in Practice, 69, 103740. https://doi.org/10.1016/j.nepr.2023.103740
Study at a glance
From the registry record, last updated by the sponsor on 25 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Puzzle-Based Safe Intravenous Therapy Applications on Students' Knowledge Level, Knowledge Retention, and Learning Motivation: A Randomized Controlled Study
- ClinicalTrials.gov ID
- NCT07669311
- Acronym / sponsor ID
- IV:Intravenous / ADU-SBE-GK-01
- Keywords
- Nursing education Intravenous therapy, Game-based learning, Patient safety
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 81 participants (actual)
- Lead sponsor
- Aydin Adnan Menderes UniversityUniversity, hospital or other
- Study start
- 19 Nov 2025 (actual)
- Primary completion
- 8 Jan 2026 (actual)
- Study completion
- 8 Jan 2026 (actual)
- First posted
- 25 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the effect of puzzle-based education on nursing students' knowledge level, knowledge retention, and learning motivation regarding safe intravenous therapy practices. Intravenous therapy is a common but complex clinical procedure that requires accurate knowledge and skills to ensure patient safety. Traditional teaching methods may not always be sufficient to support long-term learning and student motivation. Therefore, this study uses an interactive, game-based learning approach by integrating puzzles into the education process. Nursing students are randomly assigned to either a puzzle-based learning group or a traditional education group. The study seeks to determine whether game-based learning improves learning outcomes compared to conventional teaching methods.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Traditional education group | – | – |
| Puzzle-based education group | – | Behavioral: Puzzle-based intravenous therapy education |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The target population of the study consists of third-year students enrolled in the Department of Nursing, Faculty of Nursing, Aydın Adnan Menderes University (N = 290). The study sample is planned to include third-year nursing students registered in the Safe Medication Practices course during the Fall semester of the 2025-2026 academic year at Aydın Adnan Menderes University, Faculty of Nursing.
Key inclusion criteria (3 listed)
- Be a 3rd-year undergraduate nursing student
Key exclusion criteria (1 listed)
- Being unable to regularly attend the training sessions due to academic leave, health problems, or personal reasons
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Puzzle-based intravenous therapy educationThis intervention uses puzzle-based learning activities to teach safe intravenous therapy practices to nursing students. The puzzles are designed to reinforce knowledge, improve retention, and increase motivation compared to traditional teaching methods. | Behavioural | Puzzle-based education group |
Primary outcome
Intravenous Therapy Knowledge Score
Time frame: Baseline, 1 week after completion of the intervention, and 4 weeks after completion of the intervention
Knowledge regarding safe intravenous therapy practices assessed using a researcher-developed multiple-choice questionnaire. Higher scores indicate better knowledge.
Learning Motivation Score
Time frame: 1 week after completion of the intervention
Learning motivation assessed using the Instructional Materials Motivation Survey (IMMS) and the Instructional Materials Motivation Scale (IMMS-SU). Higher scores indicate greater learning motivation.
1 secondary outcome
Knowledge Retention Score
Time frame: 4 weeks after completion of the intervention
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jun 2026.
- BackgroundKalkan, N., Güler, S., Bulut, H., & Ay, A. (2022). Views of students on the use of crossword and word search puzzle as a teaching technique in nursing education: A mixed-method study. Nurse Education Today, 113, 105542. https://doi.org/10.1016/j.nedt.2022.105542 Shawahna, R., & Jaber, M. (2020). Crossword puzzles improve learning of Palestinian nursing students about pharmacology of epilepsy: Results of a randomized controlled study. Nurse Education Today, 108, 107024. https://doi.org/10.1016/j.yebeh.2020.107024 Alexandrou, E., et al. (2018). Use of short peripheral intravenous catheters: Characteristics, management, and outcomes worldwide. Journal of Hospital Medicine, 22(30), 1-7. https://doi.org/10.12788/jhm.3039 Ergin Doğan, S., & Aslan, H. (2024). Hemşirelik eğitiminde kullanılan güncel öğretim yöntem ve teknikleri. Bingöl Üniversitesi Sağlık Dergisi, 5(1), 224-235. https://doi.org/10.58605/bingolsaglik.1448021 Tosun, Ö., İ. K., & Doğan, S. D. (2023). The effect of crossword puzzles on nursing students' learning of concepts related to pain management course: A randomized controlled trial. Nurse Education in Practice, 69, 103740. https://doi.org/10.1016/j.nepr.2023.103740
- Official clinical trials registry providing information on study protocols.Link provided by the sponsor.
- Aydın Adnan Menderes University official website.Link provided by the sponsor.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Safe Intravenous Therapy Practices in Nursing Students, run by Aydin Adnan Menderes University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Intravenous Therapy Knowledge Score (time frame: Baseline, 1 week after completion of the intervention, and 4 weeks after completion of the intervention). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07669311, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jun 2026.