Cognition ImpairmentNCT07678476
Brisk Walking and Baduanjin Improve Inhibitory Function in Older Adults With Cognitive Impairment
A study testing exercise intervention in people with Cognition Impairment, run by Shanghai University of Sport at 1 site in China.
Trial summary
This study aims to investigate the acute effects of single-session different forms of aerobic exercise (brisk walking and Baduanjin) on inhibitory function and resting-state EEG power in older adults with cognitive impairment, providing scientific evidence for developing exercise intervention programs for this… Read more about this study
- Who is it for?
- Ages 60 years and older
- Conditions the study is for
- Cognition Impairment
- What is being tested?
- exercise intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteChina
- Study dates
- 1 Aug 2025to 10 Apr 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age ≥ 60 years, regardless of gender;
- Right-handed;
- Montreal Cognitive Assessment (MoCA) score ≤ 25;
- Normal or corrected-to-normal vision;
- Normal hearing;
- Signed informed consent.
Who cannot join
- Presence of severe cognitive impairment or other neurodegenerative diseases;
- Presence of psychiatric disorders, or current or long-term use of psychotropic medications;
- Presence of severe cardiovascular diseases (e.g., heart failure, atherosclerosis, myocardial infarction, etc.);
- Presence of severe muscle diseases, or a history of lower limb injury within the past six months that would preclude the ability to stand for extended periods.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Single-Session Brisk Walking and Baduanjin Exercise on Inhibitory Function in Older Adults With Cognitive Impairment: An Exploration of Resting-State EEG Mechanisms
This study aims to investigate the acute effects of single-session different forms of aerobic exercise (brisk walking and Baduanjin) on inhibitory function and resting-state EEG power in older adults with cognitive impairment, providing scientific evidence for developing exercise intervention programs for this population.
Specifically, this study seeks to answer the following core questions:
Read more
- Can a single session of brisk walking and a single session of Baduanjin exercise improve reaction time and accuracy on the Stroop color-word task in older adults with cognitive impairment?
- Are there differential effects on inhibitory function between the two exercise modalities?
- Does a single exercise session induce immediate changes in resting-state EEG power spectrum across multiple frequency bands (δ, θ, α, β)?
- Are changes in resting-state EEG power associated with improvements in inhibitory function?
Forty-five older adults with cognitive impairment will be randomly assigned to three groups (n=15 each): brisk walking group, Baduanjin group, and control group (quiet seated rest). Participants in the brisk walking and Baduanjin groups will each perform a single 30-minute moderate-intensity exercise session. All participants will complete the Stroop color-word task (assessing reaction time and accuracy under both congruent and incongruent conditions) and undergo a 5-minute eyes-closed resting-state EEG recording before and immediately after the intervention.
- Conditions
- Cognition Impairment
- Being tested
- exercise intervention
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
exercise interventionBehavioural
The brisk walking protocol was designed in accordance with the standards promulgated by the General Administration of Sport of China in 2017. The Baduanjin exercise was based on the "Health Qigong · Baduanjin" protocol promulgated by the General Administration of Sport of China in 2003.
| Study group | Role | What they receive |
|---|---|---|
| brisk walking group | Experimental | Single exercise session, duration 30 minutes Receives: Behavioral: exercise intervention |
| Baduanjin group | Experimental | Single exercise session, duration 30 minutes Receives: Behavioral: exercise intervention |
| control group | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Inhibitory Function Assessed by the Stroop Color-Word Test
Inhibitory function will be assessed using the Stroop color-word test. Participants are required to name the color of the ink while inhibiting the automatic tendency to read the word. The outcome measure is the change from baseline in accuracy rate (%) under both congruent and incongruent conditions immediately post-intervention.
Measured: Baseline and immediately post-intervention (approximately 30 minutes after the exercise session)
Change in Inhibitory Function Assessed by the Stroop Color-Word Test
Inhibitory function will be assessed using the Stroop color-word test. Participants are required to name the color of the ink while inhibiting the automatic tendency to read the word. The outcome measure is the change from baseline in reaction time (milliseconds) under both congruent and incongruent conditions immediately post-intervention.
Measured: Baseline and immediately post-intervention (approximately 30 minutes after the exercise session
Secondary outcomes (1)
Change in Resting-State EEG Power Spectrum
Resting-state electroencephalography (EEG) will be recorded for 5 minutes with eyes closed. The outcome measure is the change from baseline in absolute power across multiple frequency bands: delta (1-4 Hz), theta (4-8 Hz), alpha (8-12 Hz), and beta (12-30 Hz). EEG power will be calculated for five brain regions (frontal, central, temporal, parietal, and occipital).
Measured: Baseline and immediately post-intervention (approximately 30 minutes after the exercise session)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jul 2026
- Study start1 Aug 2025
- Primary completion30 Dec 2025
- Study completion10 Apr 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cognition ImpairmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 45 participants (actual)
Sponsor and investigators
- Lead sponsor
- Shanghai University of Sport
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ding Feng, Shanghai University of Sport
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07678476
- Sponsor's protocol ID
- 2026A122
- Status last verified
- Jul 2026
- First submitted
- 25 Jun 2026
- Last updated
- 11 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: De-identified data supporting the findings of this study are available from the corresponding author upon reasonable request for legitimate academic purposes, subject to approval by the research team and, where necessary, the relevant ethics committee, and under an appropriate data-use agreement.
Study at a glance
From the registry record, last updated by the sponsor on 11 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Single-Session Brisk Walking and Baduanjin Exercise on Inhibitory Function in Older Adults With Cognitive Impairment: An Exploration of Resting-State EEG Mechanisms
- ClinicalTrials.gov ID
- NCT07678476
- Acronym / sponsor ID
- 2026A122
- Conditions
- Cognition Impairment
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 45 participants (actual)
- Lead sponsor
- Shanghai University of SportUniversity, hospital or other
- Study start
- 1 Aug 2025 (actual)
- Primary completion
- 30 Dec 2025 (actual)
- Study completion
- 10 Apr 2026 (actual)
- First posted
- 1 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to investigate the acute effects of single-session different forms of aerobic exercise (brisk walking and Baduanjin) on inhibitory function and resting-state EEG power in older adults with cognitive impairment, providing scientific evidence for developing exercise intervention programs for this population.
Specifically, this study seeks to answer the following core questions:
- Can a single session of brisk walking and a single session of Baduanjin exercise improve reaction time and accuracy on the Stroop color-word task in older adults with cognitive impairment?
- Are there differential effects on inhibitory function between the two exercise modalities?
- Does a single exercise session induce immediate changes in resting-state EEG power spectrum across multiple frequency bands (δ, θ, α, β)?
- Are changes in resting-state EEG power associated with improvements in inhibitory function?
Forty-five older adults with cognitive impairment will be randomly assigned to three groups (n=15 each): brisk walking group, Baduanjin group, and control group (quiet seated rest). Participants in the brisk walking and Baduanjin groups will each perform a single 30-minute moderate-intensity exercise session. All participants will complete the Stroop color-word task (assessing reaction time and accuracy under both congruent and incongruent conditions) and undergo a 5-minute eyes-closed resting-state EEG recording before and immediately after the intervention.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| brisk walking group | Experimental | Behavioral: exercise interventionSingle exercise session, duration 30 minutes |
| Baduanjin group | Experimental | Behavioral: exercise interventionSingle exercise session, duration 30 minutes |
| control group | No intervention | – |
Who may qualify
- Ages
- 60 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Age ≥ 60 years, regardless of gender;
- Right-handed;
- Montreal Cognitive Assessment (MoCA) score ≤ 25;
- Normal or corrected-to-normal vision;
- Normal hearing;
Key exclusion criteria (4 listed)
- Presence of severe cognitive impairment or other neurodegenerative diseases;
- Presence of psychiatric disorders, or current or long-term use of psychotropic medications;
- Presence of severe cardiovascular diseases (e.g., heart failure, atherosclerosis, myocardial infarction, etc.);
- Presence of severe muscle diseases, or a history of lower limb injury within the past six months that would preclude the ability to stand for extended periods.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| exercise interventionThe brisk walking protocol was designed in accordance with the standards promulgated by the General Administration of Sport of China in 2017. The Baduanjin exercise was based on the "Health Qigong · Baduanjin" protocol promulgated by the General Administration of Sport of China in 2003. | Behavioural | Baduanjin group, brisk walking group |
Primary outcome
Change in Inhibitory Function Assessed by the Stroop Color-Word Test
Time frame: Baseline and immediately post-intervention (approximately 30 minutes after the exercise session)
Inhibitory function will be assessed using the Stroop color-word test. Participants are required to name the color of the ink while inhibiting the automatic tendency to read the word. The outcome measure is the change from baseline in accuracy rate (%) under both congruent and incongruent conditions immediately post-intervention.
Change in Inhibitory Function Assessed by the Stroop Color-Word Test
Time frame: Baseline and immediately post-intervention (approximately 30 minutes after the exercise session
Inhibitory function will be assessed using the Stroop color-word test. Participants are required to name the color of the ink while inhibiting the automatic tendency to read the word. The outcome measure is the change from baseline in reaction time (milliseconds) under both congruent and incongruent conditions immediately post-intervention.
1 secondary outcome
Change in Resting-State EEG Power Spectrum
Time frame: Baseline and immediately post-intervention (approximately 30 minutes after the exercise session)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Aug 2026.
- Individual participant dataSharing planned: No. De-identified data supporting the findings of this study are available from the corresponding author upon reasonable request for legitimate academic purposes, subject to approval by the research team and, where necessary, the relevant ethics committee, and under an appropriate data-use agreement.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing exercise intervention in people with Cognition Impairment, run by Shanghai University of Sport at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Inhibitory Function Assessed by the Stroop Color-Word Test (time frame: Baseline and immediately post-intervention (approximately 30 minutes after the exercise session)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Aug 2026.