Grade-II Cervical SpondylosisNCT07679373
Effects of Clinical Based Versus Synchronized Telerehabilitation on Pain, Exercise Adherence, and Functional Disability Among Patients With Grade-II Cervical Spondylosis.
A study testing Group A: Clinical Based Rehabilitation and Group B: Synchronized Telerehabilitation in people with Grade-II Cervical Spondylosis, run by Lahore University of Biological and Applied Sciences at 1 site in Pakistan.
Trial summary
This randomized controlled trial aims to compare the effects of clinical-based rehabilitation and synchronized telerehabilitation on pain, exercise adherence, and functional disability in patients with Grade-II cervical spondylosis. A total of 52 participants will be randomly allocated into two parallel groups. Read more about this study
- Who is it for?
- Ages 45 to 64 years
- Conditions the study is for
- Grade-II Cervical Spondylosis
- What is being tested?
- Group A: Clinical Based Rehabilitation and Group B: Synchronized Telerehabilitation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Jul 2026to 30 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 64 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Middle age adults (45-64) years
- Both gender ( male and female )
- Clinical daignosis of cervical spondylosis grade 2
- Mild to moderate pain on NPRS
- Sub acute stage ( 2-6 weeks) of grade 2 cervical spondylosis
- Able to follow instructions and give informed consent (cognitively able) Neurologically stable
Who cannot join
- Prior cervical spine surgery within the last 1 months or cervical instability.
- Inflammtory or systemic rheumatologic disease affecting the cervical spine (e.g., active rheumatoid arthritis ) or infection, tumor, fracture.
- Severe cardiopulmonary or other medical comorbidity that contraindicates exercise (unstable angina, uncontriolled hypertension, recent MI)
- Severe hearing or visual impairment
- No smoking and daibetic history
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site
University of Biological and Applied Sciences
Lahore, Punjab Province, 54000
About this study
This randomized controlled trial aims to compare the effects of clinical-based rehabilitation and synchronized telerehabilitation on pain, exercise adherence, and functional disability in patients with Grade-II cervical spondylosis. A total of 52 participants will be randomly allocated into two parallel groups. Both groups will receive a standardized 6-week rehabilitation program, including cervical mobility exercises, strengthening, isometric exercises, stretching, and Mulligan self-mobilization techniques. The clinical group will receive in-person physiotherapy, while the telerehabilitation group will undergo real-time supervised sessions via video conferencing. Outcome measures will include pain (Numeric Pain Rating Scale), functional disability (Neck Disability Index), and exercise adherence (Exercise Adherence Rating Scale), assessed at baseline and post-intervention. The study aims to determine whether synchronized telerehabilitation is as effective as clinical-based rehabilitation and may provide a more accessible alternative for delivering physiotherapy care.
Read the detailed description
Cervical spondylosis is a common degenerative condition of the cervical spine characterized by disc degeneration, osteophyte formation, and reduced cervical mobility, leading to neck pain and functional limitations. Grade-II cervical spondylosis represents a stage where patients are symptomatic but remain suitable for conservative management. Physiotherapy, particularly exercise-based rehabilitation, is widely used to improve pain, mobility, and functional capacity through strengthening, stretching, and neuromuscular re-education.
Clinical-based rehabilitation provides in-person physiotherapy with direct supervision, manual guidance, and real-time correction of exercises. However, access to such care is often limited due to barriers such as travel distance, cost, and time constraints. Synchronized telerehabilitation, delivered through real-time video conferencing, offers a potential alternative by enabling remote supervision, feedback, and patient engagement while maintaining continuity of care.
This randomized controlled trial aims to compare the effectiveness of clinical-based rehabilitation and synchronized telerehabilitation in patients with Grade-II cervical spondylosis. A total of 52 participants will be randomly assigned to two parallel groups. Both groups will receive a standardized 6-week rehabilitation program consisting of cervical range-of-motion exercises, deep cervical muscle strengthening, isometric exercises, stretching of the upper trapezius and levator scapulae, and Mulligan self-mobilization techniques (SNAGs). The clinical group will attend in-person sessions, while the telerehabilitation group will receive real-time supervised sessions via video conferencing.
Outcome measures include pain intensity assessed by the Numeric Pain Rating Scale (NPRS), functional disability measured by the Neck Disability Index (NDI), and exercise adherence evaluated using the Exercise Adherence Rating Scale (EARS), assessed at baseline and post-intervention.This study aims to determine whether synchronized telerehabilitation is comparable to clinical-based rehabilitation and may provide an accessible, cost-effective alternative for delivering physiotherapy care
- Conditions
- Grade-II Cervical Spondylosis
- Being tested
- Group A: Clinical Based Rehabilitation, Group B: Synchronized Telerehabilitation
- Keywords
- Telerehabilitation, Pain, Excercise Adherence, Functional Disability, Cervical Spondylosis
- Medical subject headings
- Pain, Spondylosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Group A: Clinical Based RehabilitationOther
The first intervention is clinical-based rehabilitation, delivered through in-person physiotherapy sessions in an outpatient clinical setting. Participants will receive supervised treatment three times per week for 6 weeks, with each session lasting approximately 30-40 minutes. All sessions will be conducted by a qualified physiotherapist who will provide direct monitoring, guidance, and correction to ensure proper execution of therapy. This conventional rehabilitation approach emphasizes face-to-face interaction, allowing individualized attention and real-time clinical decision-making. Participants will also be advised to continue prescribed home-based activities on non-session days to maintain consistency and support recovery outcomes.
Group B: Synchronized TelerehabilitationOther
The second intervention is synchronized telerehabilitation, delivered through real-time video conferencing sessions. Participants will receive supervised physiotherapy remotely three times per week for 6 weeks, with each session lasting approximately 30-40 minutes. A qualified physiotherapist will provide live instruction, monitoring, and feedback to ensure correct performance and safety during exercises. This approach replicates the structure of clinical-based rehabilitation while eliminating the need for in-person visits. Participants will also be given standardized home-based activity instructions for non-session days to maintain continuity of care. The intervention aims to evaluate the effectiveness of remote, technology-based rehabilitation in improving clinical outcomes in patients with Grade-II cervical spondylosis.
| Study group | Role | What they receive |
|---|---|---|
| Group A: Clinical Based Rehabilitation | Experimental | Participants in Group A will receive clinical-based rehabilitation through in-person physiotherapy sessions in an outpatient setting. Treatment will be delivered three times per week for 6 weeks, with each session lasting approximately 30-40 minutes. All interventions will be provided under the direct supervision of a qualified physiotherapist, ensuring proper monitoring, guidance, and correction of patient performance during therapy sessions. Participants will also receive standardized instructions for home-based continuation of care on non-supervised days to support consistency of rehabilitation. The focus of this arm is to evaluate the effectiveness of traditional face-to-face physiotherapy care in improving pain, functional disability, and exercise-related outcomes in patients with Grade-II cervical spondylosis. Receives: Other: Group A: Clinical Based Rehabilitation |
| Group B: Synchronized Telerehabilitation | Active comparator | Participants in Group B will receive synchronized telerehabilitation delivered through real-time video conferencing. Sessions will be conducted three times per week for 6 weeks, with each session lasting approximately 30-40 minutes. Rehabilitation will be supervised live by a qualified physiotherapist who will provide instruction, monitoring, and feedback during each session to ensure correct performance and safety. This remote delivery model will replicate the structure of clinical-based rehabilitation while eliminating the need for in-person visits. Participants will also be given standardized guidance for continuing home-based activities on non-session days. This arm aims to evaluate the effectiveness of synchronized telehealth-based physiotherapy in improving pain, functional disability, and exercise adherence in patients with Grade-II cervical spondylosis. Receives: Other: Group B: Synchronized Telerehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Intensity
Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain). Participants will rate their average neck pain over the past 24 hours. The NPRS is a valid and reliable tool widely used in musculoskeletal conditions, including cervical spondylosis, to measure changes in pain severity.
Measured: Measured at baseline (pre-intervention) and after 6 weeks (post-intervention completion).
Functional Disability
Functional disability will be assessed using the Neck Disability Index (NDI), a validated questionnaire designed to measure the impact of neck pain on daily activities. It includes domains such as pain intensity, personal care, lifting, reading, work, concentration, sleep, and recreation. Each item is scored, with higher total scores indicating greater disability. The NDI is widely used in cervical spine disorders due to its strong reliability, validity, and sensitivity to clinical change.
Measured: Measured at baseline (pre-intervention) and at 6 weeks post-intervention completion.
Exercise Adherence
Exercise adherence will be assessed using the Exercise Adherence Rating Scale (EARS), a validated self-reported questionnaire designed to measure the extent to which patients comply with prescribed home exercise programs. It evaluates behaviors such as frequency of exercise performance, consistency in following instructions, and patient commitment to rehabilitation. The scale provides insight into adherence patterns that directly influence treatment effectiveness in musculoskeletal conditions. Higher scores indicate better adherence to the prescribed exercise regimen. The EARS is widely used in rehabilitation research due to its good reliability and internal consistency.
Measured: Measured at baseline and at 6 weeks post-intervention completion.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jul 2026
- Study start1 Jul 2026 (estimated)
- Primary completionOct 2026 (estimated)
- Study completion30 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Grade-II Cervical SpondylosisStudies of the same condition, open and under way.
- More trials run by Lahore University of Biological and Applied SciencesThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 52 participants (estimated)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dr. Khizra Hamid, Lahore University of Biological and Applied Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07679373
- Sponsor's protocol ID
- UBAS/ERB/26/04/034
- Status last verified
- May 2026
- First submitted
- 25 Jun 2026
- Last updated
- 1 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: baseline participants
Study at a glance
From the registry record, last updated by the sponsor on 1 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Clinical Based Versus Synchronized Telerehabilitation on Pain, Exercise Adherence, and Functional Disability Among Patients With Grade-II Cervical Spondylosis.
- ClinicalTrials.gov ID
- NCT07679373
- Acronym / sponsor ID
- UBAS/ERB/26/04/034
- Conditions
- Grade-II Cervical Spondylosis
- Keywords
- Telerehabilitation, Pain, Excercise Adherence, Functional Disability, Cervical Spondylosis
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 52 participants (estimated)
- Lead sponsor
- Lahore University of Biological and Applied SciencesUniversity, hospital or other
- Study start
- 1 Jul 2026 (estimated)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- 30 Nov 2026 (estimated)
- First posted
- 1 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial aims to compare the effects of clinical-based rehabilitation and synchronized telerehabilitation on pain, exercise adherence, and functional disability in patients with Grade-II cervical spondylosis. A total of 52 participants will be randomly allocated into two parallel groups. Both groups will receive a standardized 6-week rehabilitation program, including cervical mobility exercises, strengthening, isometric exercises, stretching, and Mulligan self-mobilization techniques. The clinical group will receive in-person physiotherapy, while the telerehabilitation group will undergo real-time supervised sessions via video conferencing. Outcome measures will include pain (Numeric Pain Rating Scale), functional disability (Neck Disability Index), and exercise adherence (Exercise Adherence Rating Scale), assessed at baseline and post-intervention. The study aims to determine whether synchronized telerehabilitation is as effective as clinical-based rehabilitation and may provide a more accessible alternative for delivering physiotherapy care.
Detailed description
Cervical spondylosis is a common degenerative condition of the cervical spine characterized by disc degeneration, osteophyte formation, and reduced cervical mobility, leading to neck pain and functional limitations. Grade-II cervical spondylosis represents a stage where patients are symptomatic but remain suitable for conservative management. Physiotherapy, particularly exercise-based rehabilitation, is widely used to improve pain, mobility, and functional capacity through strengthening, stretching, and neuromuscular re-education.
Clinical-based rehabilitation provides in-person physiotherapy with direct supervision, manual guidance, and real-time correction of exercises. However, access to such care is often limited due to barriers such as travel distance, cost, and time constraints. Synchronized telerehabilitation, delivered through real-time video conferencing, offers a potential alternative by enabling remote supervision, feedback, and patient engagement while maintaining continuity of care.
This randomized controlled trial aims to compare the effectiveness of clinical-based rehabilitation and synchronized telerehabilitation in patients with Grade-II cervical spondylosis. A total of 52 participants will be randomly assigned to two parallel groups. Both groups will receive a standardized 6-week rehabilitation program consisting of cervical range-of-motion exercises, deep cervical muscle strengthening, isometric exercises, stretching of the upper trapezius and levator scapulae, and Mulligan self-mobilization techniques (SNAGs). The clinical group will attend in-person sessions, while the telerehabilitation group will receive real-time supervised sessions via video conferencing.
Outcome measures include pain intensity assessed by the Numeric Pain Rating Scale (NPRS), functional disability measured by the Neck Disability Index (NDI), and exercise adherence evaluated using the Exercise Adherence Rating Scale (EARS), assessed at baseline and post-intervention.This study aims to determine whether synchronized telerehabilitation is comparable to clinical-based rehabilitation and may provide an accessible, cost-effective alternative for delivering physiotherapy care
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A: Clinical Based Rehabilitation | Experimental | Other: Group A: Clinical Based RehabilitationParticipants in Group A will receive clinical-based rehabilitation through in-person physiotherapy sessions in an outpatient setting. Treatment will be delivered three times per week for 6 weeks, with each session lasting approximately 30-40 minutes. All interventions will be provided under the direct supervision of a qualified physiotherapist, ensuring proper monitoring, guidance, and correction of patient performance during therapy sessions. Participants will also receive standardized instructions for home-based continuation of care on non-supervised days to support consistency of rehabilitation. The focus of this arm is to evaluate the effectiveness of traditional face-to-face physiotherapy care in improving pain, functional disability, and exercise-related outcomes in patients with Grade-II cervical spondylosis. |
| Group B: Synchronized Telerehabilitation | Active comparator | Other: Group B: Synchronized TelerehabilitationParticipants in Group B will receive synchronized telerehabilitation delivered through real-time video conferencing. Sessions will be conducted three times per week for 6 weeks, with each session lasting approximately 30-40 minutes. Rehabilitation will be supervised live by a qualified physiotherapist who will provide instruction, monitoring, and feedback during each session to ensure correct performance and safety. This remote delivery model will replicate the structure of clinical-based rehabilitation while eliminating the need for in-person visits. Participants will also be given standardized guidance for continuing home-based activities on non-session days. This arm aims to evaluate the effectiveness of synchronized telehealth-based physiotherapy in improving pain, functional disability, and exercise adherence in patients with Grade-II cervical spondylosis. |
Who may qualify
- Ages
- 45 to 64 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Middle age adults (45-64) years
- Both gender ( male and female )
- Clinical daignosis of cervical spondylosis grade 2
- Mild to moderate pain on NPRS
- Sub acute stage ( 2-6 weeks) of grade 2 cervical spondylosis
Key exclusion criteria (5 listed)
- Prior cervical spine surgery within the last 1 months or cervical instability.
- Inflammtory or systemic rheumatologic disease affecting the cervical spine (e.g., active rheumatoid arthritis ) or infection, tumor, fracture.
- Severe cardiopulmonary or other medical comorbidity that contraindicates exercise (unstable angina, uncontriolled hypertension, recent MI)
- Severe hearing or visual impairment
- No smoking and daibetic history
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Group A: Clinical Based RehabilitationThe first intervention is clinical-based rehabilitation, delivered through in-person physiotherapy sessions in an outpatient clinical setting. Participants will receive supervised treatment three times per week for 6 weeks, with each session lasting approximately 30-40 minutes. All sessions will be conducted by a qualified physiotherapist who will provide direct monitoring, guidance, and correction to ensure proper execution of therapy. This conventional rehabilitation approach emphasizes face-to-face interaction, allowing individualized attention and real-time clinical decision-making. Participants will also be advised to continue prescribed home-based activities on non-session days to maintain consistency and support recovery outcomes. | Other | Group A: Clinical Based Rehabilitation |
| Group B: Synchronized TelerehabilitationThe second intervention is synchronized telerehabilitation, delivered through real-time video conferencing sessions. Participants will receive supervised physiotherapy remotely three times per week for 6 weeks, with each session lasting approximately 30-40 minutes. A qualified physiotherapist will provide live instruction, monitoring, and feedback to ensure correct performance and safety during exercises. This approach replicates the structure of clinical-based rehabilitation while eliminating the need for in-person visits. Participants will also be given standardized home-based activity instructions for non-session days to maintain continuity of care. The intervention aims to evaluate the effectiveness of remote, technology-based rehabilitation in improving clinical outcomes in patients with Grade-II cervical spondylosis. | Other | Group B: Synchronized Telerehabilitation |
Primary outcome
Pain Intensity
Time frame: Measured at baseline (pre-intervention) and after 6 weeks (post-intervention completion).
Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain). Participants will rate their average neck pain over the past 24 hours. The NPRS is a valid and reliable tool widely used in musculoskeletal conditions, including cervical spondylosis, to measure changes in pain severity.
Functional Disability
Time frame: Measured at baseline (pre-intervention) and at 6 weeks post-intervention completion.
Functional disability will be assessed using the Neck Disability Index (NDI), a validated questionnaire designed to measure the impact of neck pain on daily activities. It includes domains such as pain intensity, personal care, lifting, reading, work, concentration, sleep, and recreation. Each item is scored, with higher total scores indicating greater disability. The NDI is widely used in cervical spine disorders due to its strong reliability, validity, and sensitivity to clinical change.
Exercise Adherence
Time frame: Measured at baseline and at 6 weeks post-intervention completion.
Exercise adherence will be assessed using the Exercise Adherence Rating Scale (EARS), a validated self-reported questionnaire designed to measure the extent to which patients comply with prescribed home exercise programs. It evaluates behaviors such as frequency of exercise performance, consistency in following instructions, and patient commitment to rehabilitation. The scale provides insight into adherence patterns that directly influence treatment effectiveness in musculoskeletal conditions. Higher scores indicate better adherence to the prescribed exercise regimen. The EARS is widely used in rehabilitation research due to its good reliability and internal consistency.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Jul 2026.
- Individual participant dataSharing planned: Yes. baseline participants
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Group A: Clinical Based Rehabilitation and Group B: Synchronized Telerehabilitation in people with Grade-II Cervical Spondylosis, run by Lahore University of Biological and Applied Sciences at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 1 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Shoaib Waqas (+923024552109, shoaibwaqas@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Intensity (time frame: Measured at baseline (pre-intervention) and after 6 weeks (post-intervention completion).). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Jul 2026.