VeneerNCT07691658
Clinical Evaluation of Prefabricated Versus 3D-Printed Composite Resin Veneers: in Vivo Study
A study testing Prefabricated Composite Resin Veneers and 3D-Printed Composite Resin Veneers in people with Veneer and Composite Restorations, run by Tanta University at 1 site in Egypt.
Trial summary
The purpose of this study is to clinically evaluate prefabricated versus 3D-printed composite resin veneers Read more about this study
- Who is it for?
- Ages 20 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Veneer, Composite Restorations, Teeth Color
- What is being tested?
- Prefabricated Composite Resin Veneers and 3D-Printed Composite Resin Veneers
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 25 Apr 2025to 29 Apr 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Good oral hygiene and satisfactory periodontal health
- Patients requiring esthetic rehabilitation of anterior teeth
- Presence of enough enamel for bonding
Who cannot join
- Non-vital teeth or teeth requiring endodontic treatment
- Severe malocclusion or parafunctional habits (e.g., bruxism or clenching)
- Patients with severe intrinsic discoloration requiring alternative treatment
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Restorative Department, Faculty of Dentistry, Tanta University
Tanta, Tanta, 31527
About this study
The purpose of this study is to clinically evaluate prefabricated versus 3D-printed composite resin veneers
Read the detailed description
Dental veneers are now a commonly used conservative treatment to improve the appearance and functionality of anterior teeth that have enamel flaws, diastemas, small abnormalities, and discoloration. Compared to ceramic veneers, composite resin veneers have a number of benefits, such as requiring less tooth preparation, being less expensive, being easier to repair, and requiring less chairside time. Recent developments in composite resin technology and adhesive dentistry have further enhanced their mechanical qualities, wear resistance, and aesthetic results, making them a desirable treatment option for patients and professionals alike. There is little clinical data that directly compares the long-term performance of prefabricated and 3D-printed composite veneers, despite their growing use. The majority of research that is currently available has either examined each technique separately or has concentrated on laboratory assessments of mechanical properties. As a result, there is still not enough data to compare their clinical behavior in intraoral settings.
- Conditions
- Veneer, Composite Restorations, Teeth Color, Teeth Staining
- Being tested
- Prefabricated Composite Resin Veneers, 3D-Printed Composite Resin Veneers
- Keywords
- Prefabricated Composite Veneers, 3D-Printed Composite Veneers, Clinical, FDI criteria
- Medical subject headings
- Tooth Discoloration
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Prefabricated Composite Resin VeneersOther
Prefabricated composite resin veneer restorations used for esthetic rehabilitation of anterior teeth. Restorations will be bonded following the manufacturer's recommended adhesive protocol.
3D-Printed Composite Resin VeneersOther
Customized 3D-printed composite resin veneer restorations fabricated using digital design and additive manufacturing technology and bonded according to the manufacturer's recommended adhesive protocol
| Study group | Role | What they receive |
|---|---|---|
| Prefabricated Composite Resin Veneers | Experimental | Participants received prefabricated composite resin veneer restorations for the treatment of anterior teeth requiring esthetic rehabilitation. Veneers were placed according to the manufacturer's instructions using a standardized adhesive protocol. Receives: Other: Prefabricated Composite Resin Veneers |
| 3D-Printed Composite Resin Veneers | Experimental | Participants received customized 3D-printed composite resin veneer restorations for the treatment of anterior teeth requiring esthetic rehabilitation. Veneers were fabricated using a digital workflow and cemented according to the manufacturer's instructions using a standardized adhesive protocol Receives: Other: 3D-Printed Composite Resin Veneers |
What is being measured
The primary outcome is the main question the study is designed to answer.
Color match and stability
Clinical evaluation of color match and color stability will be performed according to the World Dental Federation (FDI) evaluation criteria by two calibrated evaluators at baseline and at 6, 9, 12, and 24 months. Veneer restorations will be assigned FDI scores ranging from 1 (clinically excellent) to 5 (clinically poor). Clinical success will be considered as scores of 1-3 and failure as scores of 4-5. Assessment will be carried out under standardized lighting conditions using visual examination and magnification. Statistical analysis will be performed to compare changes over time and between the two study groups.
Measured: 24 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jul 2026
- Study start25 Apr 2025
- Primary completion26 Apr 2027 (estimated)
- Study completion29 Apr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for VeneerStudies of the same condition, open and under way.
- More trials run by Tanta UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Tanta University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohammed Abd El Ghany Mohammed, Tanta University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07691658
- Sponsor's protocol ID
- Composite Resin Veneers
- Status last verified
- Jul 2026
- First submitted
- 2 Jul 2026
- Last updated
- 9 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Mandurino M, Cortili S, Coccoluto L, Greco K, Cantatore G, Gherlone EF, Vichi A, Paolone G. Mechanical Properties of 3D Printed vs. Subtractively Manufactured Composite Resins for Permanent Restorations: A Systematic Review. Materials (Basel). 2025 Feb 24;18(5):985. doi: 10.3390/ma18050985.
PubMed 40077210Veerapeindee P, Rungsiyakull P, Jia-Mahasap W. Wear resistance of 3D printed, milled, and prefabricated methacrylate-based resin materials: An in vitro study. J Prosthet Dent. 2025 Mar;133(3):904.e1-904.e8. doi: 10.1016/j.prosdent.2024.12.006. Epub 2024 Dec 20.
PubMed 39709262Balestra D, Lowther M, Goracci C, Mandurino M, Cortili S, Paolone G, Louca C, Vichi A. 3D Printed Materials for Permanent Restorations in Indirect Restorative and Prosthetic Dentistry: A Critical Review of the Literature. Materials (Basel). 2024 Mar 18;17(6):1380. doi: 10.3390/ma17061380.
PubMed 38541534Alghauli MA, Alqutaibi AY. 3D-printed intracoronal restorations, occlusal and laminate veneers: Clinical relevance, properties, and behavior compared to milled restorations; a systematic review and meta-analysis. J Esthet Restor Dent. 2024 Aug;36(8):1153-1170. doi: 10.1111/jerd.13228. Epub 2024 Mar 29.
PubMed 38551205Daghrery A. Color Stability, Gloss Retention, and Surface Roughness of 3D-Printed versus Indirect Prefabricated Veneers. J Funct Biomater. 2023 Sep 28;14(10):492. doi: 10.3390/jfb14100492.
PubMed 37888157
Study at a glance
From the registry record, last updated by the sponsor on 9 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Evaluation of Prefabricated Versus 3D-Printed Composite Resin Veneers: in Vivo Study
- ClinicalTrials.gov ID
- NCT07691658
- Acronym / sponsor ID
- Composite Resin Veneers
- Conditions
- Veneer, Composite Restorations, Teeth Color, Teeth Staining
- Keywords
- Prefabricated Composite Veneers, 3D-Printed Composite Veneers, Clinical, FDI criteria
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Tanta UniversityUniversity, hospital or other
- Study start
- 25 Apr 2025 (actual)
- Primary completion
- 26 Apr 2027 (estimated)
- Study completion
- 29 Apr 2027 (estimated)
- First posted
- 9 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to clinically evaluate prefabricated versus 3D-printed composite resin veneers
Detailed description
Dental veneers are now a commonly used conservative treatment to improve the appearance and functionality of anterior teeth that have enamel flaws, diastemas, small abnormalities, and discoloration. Compared to ceramic veneers, composite resin veneers have a number of benefits, such as requiring less tooth preparation, being less expensive, being easier to repair, and requiring less chairside time. Recent developments in composite resin technology and adhesive dentistry have further enhanced their mechanical qualities, wear resistance, and aesthetic results, making them a desirable treatment option for patients and professionals alike. There is little clinical data that directly compares the long-term performance of prefabricated and 3D-printed composite veneers, despite their growing use. The majority of research that is currently available has either examined each technique separately or has concentrated on laboratory assessments of mechanical properties. As a result, there is still not enough data to compare their clinical behavior in intraoral settings.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Prefabricated Composite Resin Veneers | Experimental | Other: Prefabricated Composite Resin VeneersParticipants received prefabricated composite resin veneer restorations for the treatment of anterior teeth requiring esthetic rehabilitation. Veneers were placed according to the manufacturer's instructions using a standardized adhesive protocol. |
| 3D-Printed Composite Resin Veneers | Experimental | Other: 3D-Printed Composite Resin VeneersParticipants received customized 3D-printed composite resin veneer restorations for the treatment of anterior teeth requiring esthetic rehabilitation. Veneers were fabricated using a digital workflow and cemented according to the manufacturer's instructions using a standardized adhesive protocol |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Good oral hygiene and satisfactory periodontal health
- Patients requiring esthetic rehabilitation of anterior teeth
- Presence of enough enamel for bonding
Key exclusion criteria (3 listed)
- Non-vital teeth or teeth requiring endodontic treatment
- Severe malocclusion or parafunctional habits (e.g., bruxism or clenching)
- Patients with severe intrinsic discoloration requiring alternative treatment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Prefabricated Composite Resin VeneersPrefabricated composite resin veneer restorations used for esthetic rehabilitation of anterior teeth. Restorations will be bonded following the manufacturer's recommended adhesive protocol. | Other | Prefabricated Composite Resin Veneers |
| 3D-Printed Composite Resin VeneersCustomized 3D-printed composite resin veneer restorations fabricated using digital design and additive manufacturing technology and bonded according to the manufacturer's recommended adhesive protocol | Other | 3D-Printed Composite Resin Veneers |
Primary outcome
Color match and stability
Time frame: 24 months
Clinical evaluation of color match and color stability will be performed according to the World Dental Federation (FDI) evaluation criteria by two calibrated evaluators at baseline and at 6, 9, 12, and 24 months. Veneer restorations will be assigned FDI scores ranging from 1 (clinically excellent) to 5 (clinically poor). Clinical success will be considered as scores of 1-3 and failure as scores of 4-5. Assessment will be carried out under standardized lighting conditions using visual examination and magnification. Statistical analysis will be performed to compare changes over time and between the two study groups.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Jul 2026.
- Background: PubMed 40077210Mandurino M, Cortili S, Coccoluto L, Greco K, Cantatore G, Gherlone EF, Vichi A, Paolone G. Mechanical Properties of 3D Printed vs. Subtractively Manufactured Composite Resins for Permanent Restorations: A Systematic Review. Materials (Basel). 2025 Feb 24;18(5):985. doi: 10.3390/ma18050985.
- Results publication: PubMed 39709262Veerapeindee P, Rungsiyakull P, Jia-Mahasap W. Wear resistance of 3D printed, milled, and prefabricated methacrylate-based resin materials: An in vitro study. J Prosthet Dent. 2025 Mar;133(3):904.e1-904.e8. doi: 10.1016/j.prosdent.2024.12.006. Epub 2024 Dec 20.
- Results publication: PubMed 38541534Balestra D, Lowther M, Goracci C, Mandurino M, Cortili S, Paolone G, Louca C, Vichi A. 3D Printed Materials for Permanent Restorations in Indirect Restorative and Prosthetic Dentistry: A Critical Review of the Literature. Materials (Basel). 2024 Mar 18;17(6):1380. doi: 10.3390/ma17061380.
- Results publication: PubMed 38551205Alghauli MA, Alqutaibi AY. 3D-printed intracoronal restorations, occlusal and laminate veneers: Clinical relevance, properties, and behavior compared to milled restorations; a systematic review and meta-analysis. J Esthet Restor Dent. 2024 Aug;36(8):1153-1170. doi: 10.1111/jerd.13228. Epub 2024 Mar 29.
- Results publication: PubMed 37888157Daghrery A. Color Stability, Gloss Retention, and Surface Roughness of 3D-Printed versus Indirect Prefabricated Veneers. J Funct Biomater. 2023 Sep 28;14(10):492. doi: 10.3390/jfb14100492.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Prefabricated Composite Resin Veneers and 3D-Printed Composite Resin Veneers in people with Veneer and Composite Restorations, run by Tanta University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 9 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Color match and stability (time frame: 24 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07691658, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Jul 2026.