PsoriasisNCT07693595
Nailfold Capillaroscopic Changes in Psoriasis
An observational study of Psoriasis, run by Al-Azhar University at 1 site in Egypt.
Trial summary
The goal of this observational study is to evaluate nailfold capillaroscopic changes in patients with psoriasis and to assess their correlation with disease severity. The study will also explore differences in capillaroscopic findings across different clinical types of psoriasis and skin phototypes (Fitzpatrick… Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Psoriasis
- What is being tested?
- Nailfold Capillaroscopy
- How many people
- 100 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Aug 2026to 1 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: The study will include patients clinically diagnosed with psoriasis attending the dermatology outpatient clinics at Al-Hussein and Sayed Galal University Hospitals in Cairo, Egypt during the study period.
Who may be able to join
- Patients clinically diagnosed with psoriasis.
Who cannot join
- Patients with connective tissue diseases (e.g., systemic sclerosis, SLE)
- Diabetes mellitus or peripheral vascular disease
- Current smokers
- Pregnant or lactating women
- Recent use of vasodilators or beta-blockers
- Manual workers exposed to vibrating tools
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Al-Hussein University Hospital & Sayed Galal University Hospital
Cairo, Cairo Governorate
Ahmed H Nouh, Asst Prof Derm & Venereolog, +201062034079, Dr.ahmednouh@azhar.edu.eg
About this study
Official title: Nailfold Capillaroscopic Changes in Psoriasis and Its Correlation With Disease Severity
The goal of this observational study is to evaluate nailfold capillaroscopic changes in patients with psoriasis and to assess their correlation with disease severity. The study will also explore differences in capillaroscopic findings across different clinical types of psoriasis and skin phototypes (Fitzpatrick classification). The study will include patients diagnosed with psoriasis attending dermatology outpatient clinics. Participants will undergo clinical assessment and nailfold capillaroscopy to detect microvascular changes.
- Conditions
- Psoriasis
- Being tested
- Nailfold Capillaroscopy
- Medical subject headings
- Psoriasis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nailfold CapillaroscopyOther
Also called Dermoscopy (if used for nails)
Participants will undergo nailfold capillaroscopy using a USB digital capillaroscope to assess microvascular changes in psoriatic patients. Clinical assessment including PASI score and evaluation of nail involvement will also be performed.
What is being measured
The primary outcome is the main question the study is designed to answer.
Nailfold capillaroscopic abnormalities in psoriasis patients
Detection and description of nailfold capillaroscopic (NFC) abnormalities in patients with psoriasis.
Measured: Baseline
Secondary outcomes (1)
Variation of nailfold capillaroscopic findings among different clinical types of psoriasis and correlation with disease severity (PASI score).
Correlation between PASI score and presence of NFC changes.
- Comparison of nailfold capillaroscopic findings in different types of psoriasis
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jul 2026
- Study start1 Aug 2026 (estimated)
- Primary completion1 Nov 2026 (estimated)
- Study completion1 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PsoriasisStudies of the same condition, open and under way.
- More trials run by Al-Azhar UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Al-Azhar University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Hassan Nouh MD, Al-Azhar University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07693595
- Sponsor's protocol ID
- PSO-NFC-PASI-2026
- Status last verified
- Jul 2026
- First submitted
- 4 Jul 2026
- Last updated
- 31 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Nailfold Capillaroscopic Changes in Psoriasis and Its Correlation With Disease Severity
- ClinicalTrials.gov ID
- NCT07693595
- Acronym / sponsor ID
- PSO-NFC-PASI-2026
- Conditions
- Psoriasis
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Al-Azhar UniversityUniversity, hospital or other
- Study start
- 1 Aug 2026 (estimated)
- Primary completion
- 1 Nov 2026 (estimated)
- Study completion
- 1 Dec 2026 (estimated)
- First posted
- 9 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to evaluate nailfold capillaroscopic changes in patients with psoriasis and to assess their correlation with disease severity. The study will also explore differences in capillaroscopic findings across different clinical types of psoriasis and skin phototypes (Fitzpatrick classification). The study will include patients diagnosed with psoriasis attending dermatology outpatient clinics. Participants will undergo clinical assessment and nailfold capillaroscopy to detect microvascular changes.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- The study will include patients clinically diagnosed with psoriasis attending the dermatology outpatient clinics at Al-Hussein and Sayed Galal University Hospitals in Cairo, Egypt during the study period.
Key inclusion criteria (1 listed)
- Patients clinically diagnosed with psoriasis.
Key exclusion criteria (6 listed)
- Patients with connective tissue diseases (e.g., systemic sclerosis, SLE)
- Diabetes mellitus or peripheral vascular disease
- Current smokers
- Pregnant or lactating women
- Recent use of vasodilators or beta-blockers
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nailfold CapillaroscopyAlso: Dermoscopy (if used for nails)Participants will undergo nailfold capillaroscopy using a USB digital capillaroscope to assess microvascular changes in psoriatic patients. Clinical assessment including PASI score and evaluation of nail involvement will also be performed. | Other | – |
Primary outcome
Nailfold capillaroscopic abnormalities in psoriasis patients
Time frame: Baseline
Detection and description of nailfold capillaroscopic (NFC) abnormalities in patients with psoriasis.
1 secondary outcome
Variation of nailfold capillaroscopic findings among different clinical types of psoriasis and correlation with disease severity (PASI score).
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Jul 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Psoriasis, run by Al-Azhar University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 31 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ahmed H Nouh, Asst Prof Derm & Venereol (+201062034079, Dr.ahmednouh@azhar.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Nailfold capillaroscopic abnormalities in psoriasis patients (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Jul 2026.