StrokeNCT07698522
Digital Technology-Informed Stroke Rehabilitation
A study testing Lab-based movement guidance and Home-based movement guidance in people with Stroke, run by University of Utah at 1 site in United States.
Trial summary
The goal of this study is to determine the effects of lab and home-based technology guidance during movement training post-stroke. The study will compare movement training informed by lab-based technology to training delivered with technology at home. Read more about this study
- Who is it for?
- Ages 30 to 85 years
- Conditions the study is for
- Stroke
- What is being tested?
- Lab-based movement guidance and Home-based movement guidance
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteUnited States
- Study dates
- 27 Jul 2026to Dec 2033
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age between 30-85 years.
- Diagnosis of stroke.
- Stroke onset of at least six months prior to the time of participation.
- Fugl Meyer Upper Extremity between 30-50 (mild-moderate)
- Cognitive skills to consent and actively participate, as indicated by scores of ≥ 24 on the Mini- Mental Status Examination
- Able to visit lab up to 5x per week for 3 weeks
Who cannot join
- Presence of severe aphasia preventing the ability to follow 1-step directions at least 80% of the time.
- Excessive spasticity of the wrist, elbow, and shoulder, defined as a Modified Ashworth Score >2.
- Diagnosis of neurological disorders other than stroke.
- Orthopedic/musculoskeletal conditions (e.g., severe arthritis) affecting the upper extremity.
- Currently or planning to become pregnant.
- Participation in concurrent occupational therapy.
- Unilateral neglect, defined as failure of the Line Bisection Task
- Upper extremity pain >= 7/10 on Numeric Rating Scale
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Kennecott Mechanical Engineering Building
Salt Lake City, Utah, 84112
Scott Uhlrich, PhD
About this study
The goal of this study is to determine the effects of lab and home-based technology guidance during movement training post-stroke. The study will compare movement training informed by lab-based technology to training delivered with technology at home. The main questions it aims to answer are:
- How well do lab and home-based technologies help individuals post-stroke improve their movement patterns?
- Is there a difference in improvement between the in-lab and at-home training groups?
- Which technologies lead to the most improvement?
Read the detailed description
The study is a randomized, controlled feasibility trial investigating rehabilitation to improve movement patterns after stroke. The study will recruit participants who have had a stroke that led to upper-extremity impairment. Individuals will be assigned to one of two digital technology-guided groups. One group will be guided through exercises in a home-based setting, the other will be lab-based.
Participants will engage in training sessions multiple days a week for up to 6 weeks, either in-lab or at home. Both groups will visit the lab weekly for movement assessments.
- Conditions
- Stroke
- Being tested
- Lab-based movement guidance, Home-based movement guidance
- Keywords
- movement training, rehabilitation, occupational therapy
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Lab-based movement guidanceOther
Participants will receive computer-generated guidance on how to perform different activities of daily living efficiently. The guidance will be delivered using lab-based sensing and feedback technology.
Home-based movement guidanceOther
Participants will receive computer-generated guidance on how to perform different activities of daily living efficiently. This guidance will be delivered using home-based technologies, such as a computer or tablet.
| Study group | Role | What they receive |
|---|---|---|
| At-Home Training | Experimental | Participants will train at-home. Receives: Other: Home-based movement guidance |
| In-Lab Training | Experimental | Participants will train in the lab. Receives: Other: Lab-based movement guidance |
What is being measured
The primary outcome is the main question the study is designed to answer.
Kinematic movement quality score
A score based on subject kinematics during a daily task (like reaching), comparing the subject's reaching kinematics to normative kinematics.
Measured: From enrollment to the end of treatment at 3 weeks.
Secondary outcomes (1)
FMA-UE Score
Upper Extremity Fugl-Meyer Score
Measured: From enrollment to the end of treatment at 3 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Jul 2026
- Study start27 Jul 2026
- Primary completionDec 2033 (estimated)
- Study completionDec 2033 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Utah
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Scott Uhlrich, University of Utah
- Investigators
- Scott Uhlrich, PhD, Principal investigator, University of Utah
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07698522
- Sponsor's protocol ID
- IRB_00203244
- Status last verified
- Jul 2026
- First submitted
- 6 Jul 2026
- Last updated
- 24 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: We will share participant demographics and outcomes data. We will also share kinematics data. These data will be shared on SimTK.org.
Study at a glance
From the registry record, last updated by the sponsor on 24 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Digital Technology-Informed Stroke Rehabilitation
- ClinicalTrials.gov ID
- NCT07698522
- Acronym / sponsor ID
- IRB_00203244
- Conditions
- Stroke
- Keywords
- movement training, rehabilitation, occupational therapy
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- University of UtahUniversity, hospital or other
- Study start
- 27 Jul 2026 (actual)
- Primary completion
- Dec 2033 (estimated)
- Study completion
- Dec 2033 (estimated)
- First posted
- 13 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to determine the effects of lab and home-based technology guidance during movement training post-stroke. The study will compare movement training informed by lab-based technology to training delivered with technology at home. The main questions it aims to answer are:
- How well do lab and home-based technologies help individuals post-stroke improve their movement patterns?
- Is there a difference in improvement between the in-lab and at-home training groups?
- Which technologies lead to the most improvement?
Detailed description
The study is a randomized, controlled feasibility trial investigating rehabilitation to improve movement patterns after stroke. The study will recruit participants who have had a stroke that led to upper-extremity impairment. Individuals will be assigned to one of two digital technology-guided groups. One group will be guided through exercises in a home-based setting, the other will be lab-based.
Participants will engage in training sessions multiple days a week for up to 6 weeks, either in-lab or at home. Both groups will visit the lab weekly for movement assessments.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| At-Home Training | Experimental | Other: Home-based movement guidanceParticipants will train at-home. |
| In-Lab Training | Experimental | Other: Lab-based movement guidanceParticipants will train in the lab. |
Who may qualify
- Ages
- 30 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Age between 30-85 years.
- Diagnosis of stroke.
- Stroke onset of at least six months prior to the time of participation.
- Fugl Meyer Upper Extremity between 30-50 (mild-moderate)
- Cognitive skills to consent and actively participate, as indicated by scores of ≥ 24 on the Mini- Mental Status Examination
Key exclusion criteria (8 listed)
- Presence of severe aphasia preventing the ability to follow 1-step directions at least 80% of the time.
- Excessive spasticity of the wrist, elbow, and shoulder, defined as a Modified Ashworth Score >2.
- Diagnosis of neurological disorders other than stroke.
- Orthopedic/musculoskeletal conditions (e.g., severe arthritis) affecting the upper extremity.
- Currently or planning to become pregnant.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Lab-based movement guidanceParticipants will receive computer-generated guidance on how to perform different activities of daily living efficiently. The guidance will be delivered using lab-based sensing and feedback technology. | Other | In-Lab Training |
| Home-based movement guidanceParticipants will receive computer-generated guidance on how to perform different activities of daily living efficiently. This guidance will be delivered using home-based technologies, such as a computer or tablet. | Other | At-Home Training |
Primary outcome
Kinematic movement quality score
Time frame: From enrollment to the end of treatment at 3 weeks.
A score based on subject kinematics during a daily task (like reaching), comparing the subject's reaching kinematics to normative kinematics.
1 secondary outcome
FMA-UE Score
Time frame: From enrollment to the end of treatment at 3 weeks.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Sep 2026.
- Individual participant dataSharing planned: Yes. We will share participant demographics and outcomes data. We will also share kinematics data. These data will be shared on SimTK.org.
Related trials for Stroke
Not yet recruiting
Cardiac CT Angiography in Acute Stroke Imaging (SCOPE-CT)
Acute Ischemic Stroke and Transient Ischemic Attacks
Recruiting
OPTION-EMEA Clinical Trial
Atrial Fibrillation (AF), Stroke Prevention in Patients With Atrial Fibrillation
Not yet recruitingPhase 3
Metformin in Acute Ischemic Stroke
Acute Ischemic Stroke
Recruiting
Music Therapy in Post-Stroke Patients: A Clinical Trial
CVA (Cerebrovascular Accident), Ictus
Not yet recruitingObservational study
Detecting and Predicting Post-stroke Cognitive Impairment Using the Oxford Cognitive Screen
Stroke, Ischemic Stroke
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Scott Uhlrich, PhD principal investigator
University of Utah
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Lab-based movement guidance and Home-based movement guidance in people with Stroke, run by University of Utah at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 24 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Samantha McNeill ((385) 215-9146, samantha.mcneill@utah.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Kinematic movement quality score (time frame: From enrollment to the end of treatment at 3 weeks.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Sep 2026.