Catheter MalpositionNCT07701720
Ultrasound Guidance vs. Landmark Technique for Catheter Malposition in IJV Catheterization
An observational study of Catheter Malposition and Central Venous Catheterization, run by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
Central venous catheterization (CVC) via the internal jugular vein (IJV) is a fundamental procedure in anesthesia and intensive care for hemodynamic monitoring, fluid resuscitation, and vasoactive drug administration. Read more about this study
- Who is it for?
- Ages 18 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Catheter Malposition, Central Venous Catheterization
- What is being tested?
- Ultrasound-Guided Technique and Landmark Technique
- Type of treatment
- Surgery or procedure
- How many people
- 204 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Jul 2026to 15 Oct 2026
- How long will I take part?
- 2 Days
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Adult and elderly patients (18-75 years) undergoing elective or scheduled surgery in the general operating room unit of Dicle University Faculty of Medicine Hospital who require central venous catheterization via the internal jugular vein as part of routine perioperative care. The catheterization technique (ultrasound-guided or landmark) reflects the routine practice of the performing physician; no technique is assigned by the study for research purposes.
Who may be able to join
- Patients aged 18-75 undergoing surgery requiring central venous (internal jugular) catheterization
Who cannot join
- Refusal to participate
- age <18 or >75
- emergency surgery
- coagulopathy
- infection, prior surgery, or prior cannulation at the insertion site
- allergy to ultrasound gel
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Dicle University
Diyarbakır, Eyalet/Yerleşke, 21070
About this study
Official title: The Effect of Ultrasound Guidance Versus Landmark Technique on Catheter Malposition in Internal Jugular Vein Catheterization
Central venous catheterization (CVC) via the internal jugular vein (IJV) is a fundamental procedure in anesthesia and intensive care for hemodynamic monitoring, fluid resuscitation, and vasoactive drug administration. While modern clinical guidelines strongly advocate for ultrasound (USG) guidance, the traditional anatomical landmark technique remains widely utilized due to equipment availability or clinician habits. Proper positioning of the catheter tip is critical to prevent severe long-term complications; however, comparative data regarding catheter tip malposition between these two routine techniques-especially when confirmed by postprocedural bedside chest X-ray-require further prospective evaluation. Objective:
The primary objective of this prospective observational study is to compare ultrasound-guided versus landmark techniques for internal jugular vein catheterization with respect to catheter tip malposition, as determined by postprocedural bedside chest X-ray. Secondary objectives include the evaluation of the number of needle redirections, first-attempt success rate, total procedure time, and the incidence of mechanical complications (such as accidental arterial puncture or hematoma formation)
- Being tested
- Ultrasound-Guided Technique, Landmark Technique
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound-Guided TechniqueProcedure or surgery
Internal jugular vein catheterization performed with real-time ultrasound visualization of the vein to guide needle insertion.
Landmark TechniqueProcedure or surgery
Internal jugular vein catheterization performed using external anatomical landmarks without real-time ultrasound guidance.
| Study group | Role | What they receive |
|---|---|---|
| Ultrasound-guided group | IJV catheterization performed under real-time ultrasound guidance Receives: Procedure: Ultrasound-Guided Technique | |
| Landmark technique group | IJV catheterization performed via anatomical landmark technique Receives: Procedure: Landmark Technique |
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence of catheter tip malposition
Measured: Assessed on postoperative bedside chest X-ray, immediately following the procedure
Secondary outcomes (1)
Incidence of Procedural Mechanical Complications
The occurrence and rate of immediate mechanical complications directly related to the intervention, specifically tracking accidental carotid arterial punctures and hematoma formations.
Measured: During the procedure and up to 24 hours post-operatively.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jul 2026
- Study start15 Jul 2026
- Primary completion15 Oct 2026 (estimated)
- Study completion15 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Catheter MalpositionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 204 participants (estimated)
- Target duration
- 2 Days
Sponsor and investigators
- Lead sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fikret Salık, Dicle University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07701720
- Sponsor's protocol ID
- 321/2026
- Status last verified
- Aug 2026
- First submitted
- 8 Jul 2026
- Last updated
- 2 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Riaz A, Shan Khan RA, Salim F. Ultrasound guided internal jugular venous cannulation: comparison with land-mark technique. J Coll Physicians Surg Pak. 2015 May;25(5):315-9.
PubMed 26008653
Study at a glance
From the registry record, last updated by the sponsor on 2 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Ultrasound Guidance Versus Landmark Technique on Catheter Malposition in Internal Jugular Vein Catheterization
- ClinicalTrials.gov ID
- NCT07701720
- Acronym / sponsor ID
- 321/2026
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 204 participants (estimated)
- Lead sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research HospitalUniversity, hospital or other
- Study start
- 15 Jul 2026 (actual)
- Primary completion
- 15 Oct 2026 (estimated)
- Study completion
- 15 Oct 2026 (estimated)
- First posted
- 14 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Central venous catheterization (CVC) via the internal jugular vein (IJV) is a fundamental procedure in anesthesia and intensive care for hemodynamic monitoring, fluid resuscitation, and vasoactive drug administration. While modern clinical guidelines strongly advocate for ultrasound (USG) guidance, the traditional anatomical landmark technique remains widely utilized due to equipment availability or clinician habits. Proper positioning of the catheter tip is critical to prevent severe long-term complications; however, comparative data regarding catheter tip malposition between these two routine techniques-especially when confirmed by postprocedural bedside chest X-ray-require further prospective evaluation. Objective:
The primary objective of this prospective observational study is to compare ultrasound-guided versus landmark techniques for internal jugular vein catheterization with respect to catheter tip malposition, as determined by postprocedural bedside chest X-ray. Secondary objectives include the evaluation of the number of needle redirections, first-attempt success rate, total procedure time, and the incidence of mechanical complications (such as accidental arterial puncture or hematoma formation)
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Target follow-up
- 2 Days
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Ultrasound-guided group | – | Procedure: Ultrasound-Guided TechniqueIJV catheterization performed under real-time ultrasound guidance |
| Landmark technique group | – | Procedure: Landmark TechniqueIJV catheterization performed via anatomical landmark technique |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Adult and elderly patients (18-75 years) undergoing elective or scheduled surgery in the general operating room unit of Dicle University Faculty of Medicine Hospital who require central venous catheterization via the internal jugular vein as part of routine perioperative care. The catheterization technique (ultrasound-guided or landmark) reflects the routine practice of the performing physician; no technique is assigned by the study for research purposes.
Key inclusion criteria (1 listed)
- Patients aged 18-75 undergoing surgery requiring central venous (internal jugular) catheterization
Key exclusion criteria (6 listed)
- Refusal to participate
- age <18 or >75
- emergency surgery
- coagulopathy
- infection, prior surgery, or prior cannulation at the insertion site
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound-Guided TechniqueInternal jugular vein catheterization performed with real-time ultrasound visualization of the vein to guide needle insertion. | Procedure or surgery | Ultrasound-guided group |
| Landmark TechniqueInternal jugular vein catheterization performed using external anatomical landmarks without real-time ultrasound guidance. | Procedure or surgery | Landmark technique group |
Primary outcome
Incidence of catheter tip malposition
Time frame: Assessed on postoperative bedside chest X-ray, immediately following the procedure
1 secondary outcome
Incidence of Procedural Mechanical Complications
Time frame: During the procedure and up to 24 hours post-operatively.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Sep 2026.
- Background: PubMed 26008653Riaz A, Shan Khan RA, Salim F. Ultrasound guided internal jugular venous cannulation: comparison with land-mark technique. J Coll Physicians Surg Pak. 2015 May;25(5):315-9.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Catheter Malposition and Central Venous Catheterization, run by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 2 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incidence of catheter tip malposition (time frame: Assessed on postoperative bedside chest X-ray, immediately following the procedure). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07701720, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Sep 2026.