ExophthalmometryHERTEL-MXNCT07705061
Hertel Exophthalmometry Values in Mexican Adults
An observational study of Exophthalmometry and Normal Exophthalmometric Values, run by Instituto de Oftalmología Fundación Conde de Valenciana at 1 site in Mexico.
Trial summary
Proptosis assessment using Hertel exophthalmometry is an essential part of the ophthalmic examination, but normal reference values vary among different populations. This observational study aims to establish normative Hertel exophthalmometry values in Mexican adults and to evaluate their association with demographic… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Exophthalmometry, Normal Exophthalmometric Values
- What is being tested?
- Hertel Exophthalmometry
- How many people
- 300 participants
- Where
- 1 siteMexico
- Study dates
- 21 Apr 2026to 28 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Adult Mexican participants (≥18 years) recruited from the Ophthalmology Department who meet the eligibility criteria. Participants with and without systemic diseases will be included to establish normative Hertel exophthalmometry values and evaluate their association with demographic characteristics and systemic conditions.
Who may be able to join
- Adults aged 18 years or older.
- Mexican participants or individuals who self-identify as Mexican.
- Ability to understand the study procedures and provide written informed consent.
- Ability to undergo bilateral Hertel exophthalmometry.
- Participants with or without previously diagnosed systemic diseases.
Who cannot join
- Active thyroid eye disease
- History of orbital trauma or orbital fracture.
- Previous orbital surgery, orbital decompression, or surgery that may alter globe position.
- Presence or history of an orbital tumor, orbital inflammation, or orbital infection.
- Craniofacial abnormalities or facial asymmetry that may interfere with Hertel exophthalmometry.
- Ocular or eyelid conditions that prevent accurate positioning or measurement with the Hertel exophthalmometer.
- Inability to cooperate with the examination or obtain a reliable exophthalmometry measurement.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Mexico1 site, 1 recruiting
- Recruiting
✔ Instituto de Oftalmología Fundación Conde de Valenciana IAP
Mexico City, Mexico City, 94806
Roberto Ramirez Hernandez, 5525137712, robert.rami.rr@gmail.com
About this study
Official title: Hertel Exophthalmometry Values in Mexican Adults and Their Association With Demographic Factors and Systemic Diseases
Proptosis assessment using Hertel exophthalmometry is an essential part of the ophthalmic examination, but normal reference values vary among different populations. This observational study aims to establish normative Hertel exophthalmometry values in Mexican adults and to evaluate their association with demographic characteristics (such as age and sex) and systemic diseases. Healthy adult participants and adults with selected systemic conditions will undergo standardized Hertel exophthalmometry measurements. The findings are expected to provide population-specific reference values that may improve the clinical assessment of orbital diseases in the Mexican population.
Read the detailed description
Background: Hertel exophthalmometry is the most commonly used method for measuring globe protrusion in clinical practice. Normal exophthalmometric values vary according to ethnicity, sex, age, and craniofacial anatomy; therefore, population-specific reference values are necessary for accurate clinical interpretation. Currently, normative data for Mexican adults are limited.
Objective: To establish normative Hertel exophthalmometry values in Mexican adults and to evaluate their association with demographic characteristics and systemic diseases.
Methods: This is a prospective observational study. Adult participants attending the Ophthalmology Department will be consecutively recruited after providing written informed consent. Hertel exophthalmometry measurements will be obtained using a standardized technique by trained examiners. Demographic information, including age and sex, as well as relevant medical history and systemic diseases, will be recorded. The primary outcome is the distribution of Hertel exophthalmometry values in the study population. Secondary analyses will assess associations between exophthalmometric measurements and demographic or systemic variables.
Expected Significance: The study will provide normative Hertel exophthalmometry values for the Mexican adult population and identify factors associated with physiological variations in globe protrusion. These findings may improve the clinical evaluation of patients with suspected orbital disease and facilitate interpretation of Hertel exophthalmometry measurements in routine ophthalmic practice.
- Conditions
- Exophthalmometry, Normal Exophthalmometric Values
- Being tested
- Hertel Exophthalmometry
- Keywords
- Hertel Exophthalmometry, Exophthalmometry, Mexican Adults, Orbital Anatomy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Hertel ExophthalmometryDiagnostic test
Standardized bilateral Hertel exophthalmometry performed using a Hertel exophthalmometer to measure globe protrusion.
| Study group | Role | What they receive |
|---|---|---|
| Mexican Adult Participants | Adult Mexican participants undergoing standardized Hertel exophthalmometry and collection of demographic and medical history information for the establishment of normative exophthalmometric values and evaluation of associated factors. Receives: Diagnostic Test: Hertel Exophthalmometry |
What is being measured
The primary outcome is the main question the study is designed to answer.
Hertel Exophthalmometry Value
Bilateral Hertel exophthalmometry measurements (millimeters) obtained using a standardized Hertel exophthalmometer. Normative values will be estimated and summarized for the study population.
Measured: At baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jul 2026
- Study start21 Apr 2026
- Primary completion28 Dec 2026 (estimated)
- Study completion28 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ExophthalmometryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 300 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07705061
- Sponsor's protocol ID
- HERTEL-MX-2026-01
- Acronym
- HERTEL-MX
- Status last verified
- Jul 2026
- First submitted
- 10 Jul 2026
- Last updated
- 15 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 15 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Hertel Exophthalmometry Values in Mexican Adults and Their Association With Demographic Factors and Systemic Diseases
- ClinicalTrials.gov ID
- NCT07705061
- Acronym / sponsor ID
- HERTEL-MX / HERTEL-MX-2026-01
- Conditions
- Exophthalmometry, Normal Exophthalmometric Values
- Keywords
- Hertel Exophthalmometry, Exophthalmometry, Mexican Adults, Orbital Anatomy
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 300 participants (estimated)
- Lead sponsor
- Instituto de Oftalmología Fundación Conde de ValencianaUniversity, hospital or other
- Study start
- 21 Apr 2026 (actual)
- Primary completion
- 28 Dec 2026 (estimated)
- Study completion
- 28 Dec 2026 (estimated)
- First posted
- 15 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Proptosis assessment using Hertel exophthalmometry is an essential part of the ophthalmic examination, but normal reference values vary among different populations. This observational study aims to establish normative Hertel exophthalmometry values in Mexican adults and to evaluate their association with demographic characteristics (such as age and sex) and systemic diseases. Healthy adult participants and adults with selected systemic conditions will undergo standardized Hertel exophthalmometry measurements. The findings are expected to provide population-specific reference values that may improve the clinical assessment of orbital diseases in the Mexican population.
Detailed description
Background: Hertel exophthalmometry is the most commonly used method for measuring globe protrusion in clinical practice. Normal exophthalmometric values vary according to ethnicity, sex, age, and craniofacial anatomy; therefore, population-specific reference values are necessary for accurate clinical interpretation. Currently, normative data for Mexican adults are limited.
Objective: To establish normative Hertel exophthalmometry values in Mexican adults and to evaluate their association with demographic characteristics and systemic diseases.
Methods: This is a prospective observational study. Adult participants attending the Ophthalmology Department will be consecutively recruited after providing written informed consent. Hertel exophthalmometry measurements will be obtained using a standardized technique by trained examiners. Demographic information, including age and sex, as well as relevant medical history and systemic diseases, will be recorded. The primary outcome is the distribution of Hertel exophthalmometry values in the study population. Secondary analyses will assess associations between exophthalmometric measurements and demographic or systemic variables.
Expected Significance: The study will provide normative Hertel exophthalmometry values for the Mexican adult population and identify factors associated with physiological variations in globe protrusion. These findings may improve the clinical evaluation of patients with suspected orbital disease and facilitate interpretation of Hertel exophthalmometry measurements in routine ophthalmic practice.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Mexican Adult Participants | – | Diagnostic Test: Hertel ExophthalmometryAdult Mexican participants undergoing standardized Hertel exophthalmometry and collection of demographic and medical history information for the establishment of normative exophthalmometric values and evaluation of associated factors. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Adult Mexican participants (≥18 years) recruited from the Ophthalmology Department who meet the eligibility criteria. Participants with and without systemic diseases will be included to establish normative Hertel exophthalmometry values and evaluate their association with demographic characteristics and systemic conditions.
Key inclusion criteria (5 listed)
- Adults aged 18 years or older.
- Mexican participants or individuals who self-identify as Mexican.
- Ability to understand the study procedures and provide written informed consent.
- Ability to undergo bilateral Hertel exophthalmometry.
- Participants with or without previously diagnosed systemic diseases.
Key exclusion criteria (7 listed)
- Active thyroid eye disease
- History of orbital trauma or orbital fracture.
- Previous orbital surgery, orbital decompression, or surgery that may alter globe position.
- Presence or history of an orbital tumor, orbital inflammation, or orbital infection.
- Craniofacial abnormalities or facial asymmetry that may interfere with Hertel exophthalmometry.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Hertel ExophthalmometryStandardized bilateral Hertel exophthalmometry performed using a Hertel exophthalmometer to measure globe protrusion. | Diagnostic test | Mexican Adult Participants |
Primary outcome
Hertel Exophthalmometry Value
Time frame: At baseline
Bilateral Hertel exophthalmometry measurements (millimeters) obtained using a standardized Hertel exophthalmometer. Normative values will be estimated and summarized for the study population.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jul 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Exophthalmometry and Normal Exophthalmometric Values, run by Instituto de Oftalmología Fundación Conde de Valenciana at 1 site in Mexico.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 15 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Mexico. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Roberto Ramirez Hernandez, MD, Ophthalmologist (+525525137712, robert.rami.rr@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Hertel Exophthalmometry Value (time frame: At baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jul 2026.