Ischemic Heart DiseaseNCT07705672
Role Of Fixed Prosthodontic Restorations on Metabolic Control of Ischemic Heart Disease Patients
A study testing Fixed Prosthodontic Rehabilitation in people with Ischemic Heart Disease, run by Dr. Moaz Mohamed at 1 site in Egypt.
Trial summary
This study evaluated the effect of fixed prosthodontic rehabilitation on metabolic parameters and masticatory efficiency in patients with ischemic heart disease. Clinical and laboratory outcomes was assessed before and after treatment. Read more about this study
- Who is it for?
- Ages 45 to 70 years
- Conditions the study is for
- Ischemic Heart Disease
- What is being tested?
- Fixed Prosthodontic Rehabilitation
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2024to 30 Nov 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients aged 45 to 70 years with diagnosed stable ischemic heart disease.
- Patients presenting with partial edentulism and compromised masticatory function due to missing teeth.
- Patients indicated for fixed prosthodontic rehabilitation.
- Patients with complete clinical records and laboratory data available at baseline and 6 months after treatment.
- Patients who provided informed consent for treatment and use of their clinical data.
Who cannot join
- uncontrolled systemic diseases affecting metabolic status (e.g., uncontrolled diabetes mellitus).
- acute cardiovascular events or unstable ischemic heart disease.
- Patients with conditions affecting oral function other than tooth loss (e.g., neuromuscular disorders).
- Patients who received removable prostheses instead of fixed prosthodontic rehabilitation.
- Patients with incomplete clinical records or missing baseline or 6-month laboratory data.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Fixed Prosthodontic Rehabilitation on Nutritional and Metabolic Parameters in Patients With Ischemic Heart Disease
This study evaluated the effect of fixed prosthodontic rehabilitation on metabolic parameters and masticatory efficiency in patients with ischemic heart disease. Clinical and laboratory outcomes was assessed before and after treatment.
- Conditions
- Ischemic Heart Disease
- Being tested
- Fixed Prosthodontic Rehabilitation
- Medical subject headings
- Myocardial Ischemia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Fixed Prosthodontic RehabilitationProcedure or surgery
Placement of fixed prosthodontic restorations to replace missing teeth and improve masticatory function.
| Study group | Role | What they receive |
|---|---|---|
| Fixed Prosthodontic Rehabilitation | Experimental | Placement of fixed prosthodontic restorations to replace missing teeth and improve masticatory function in patients with ischemic heart disease. Receives: Procedure: Fixed Prosthodontic Rehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Hemoglobin A1c (HbA1c)
Hemoglobin A1c (HbA1c) (%) measured using standard laboratory methods. The mean change in HbA1c from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Measured: Baseline and 6 months after fixed prosthodontic rehabilitation
Change in High-Density Lipoprotein Cholesterol (HDL-C)
High-density lipoprotein cholesterol (HDL-C) concentration (mg/dL) measured using standard laboratory blood analysis. The mean change in HDL-C from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Measured: Baseline and 6 months after fixed prosthodontic rehabilitation
Change in Low-Density Lipoprotein Cholesterol (LDL-C)
Low-density lipoprotein cholesterol (LDL-C) concentration (mg/dL) measured using standard laboratory blood analysis. The mean change in LDL-C from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Measured: Baseline and 6 months after fixed prosthodontic rehabilitation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jul 2026
- Study start1 Jan 2024
- Primary completion12 Sep 2025
- Study completion30 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ischemic Heart DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 90 participants (actual)
Sponsor and investigators
- Lead sponsor
- Dr. Moaz Mohamed
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Dr. Moaz Mohamed, Tanta University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07705672
- Sponsor's protocol ID
- Tanta-Dent-Cardio-2026-01
- Status last verified
- Jul 2026
- First submitted
- 6 Jul 2026
- Last updated
- 15 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Fixed Prosthodontic Rehabilitation on Nutritional and Metabolic Parameters in Patients With Ischemic Heart Disease
- ClinicalTrials.gov ID
- NCT07705672
- Acronym / sponsor ID
- Tanta-Dent-Cardio-2026-01
- Conditions
- Ischemic Heart Disease
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 90 participants (actual)
- Lead sponsor
- Dr. Moaz MohamedUniversity, hospital or other
- Study start
- 1 Jan 2024 (actual)
- Primary completion
- 12 Sep 2025 (actual)
- Study completion
- 30 Nov 2025 (actual)
- First posted
- 15 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study evaluated the effect of fixed prosthodontic rehabilitation on metabolic parameters and masticatory efficiency in patients with ischemic heart disease. Clinical and laboratory outcomes was assessed before and after treatment.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Fixed Prosthodontic Rehabilitation | Experimental | Procedure: Fixed Prosthodontic RehabilitationPlacement of fixed prosthodontic restorations to replace missing teeth and improve masticatory function in patients with ischemic heart disease. |
Who may qualify
- Ages
- 45 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Patients aged 45 to 70 years with diagnosed stable ischemic heart disease.
- Patients presenting with partial edentulism and compromised masticatory function due to missing teeth.
- Patients indicated for fixed prosthodontic rehabilitation.
- Patients with complete clinical records and laboratory data available at baseline and 6 months after treatment.
- Patients who provided informed consent for treatment and use of their clinical data.
Key exclusion criteria (5 listed)
- uncontrolled systemic diseases affecting metabolic status (e.g., uncontrolled diabetes mellitus).
- acute cardiovascular events or unstable ischemic heart disease.
- Patients with conditions affecting oral function other than tooth loss (e.g., neuromuscular disorders).
- Patients who received removable prostheses instead of fixed prosthodontic rehabilitation.
- Patients with incomplete clinical records or missing baseline or 6-month laboratory data.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Fixed Prosthodontic RehabilitationPlacement of fixed prosthodontic restorations to replace missing teeth and improve masticatory function. | Procedure or surgery | Fixed Prosthodontic Rehabilitation |
Primary outcome
Change in Hemoglobin A1c (HbA1c)
Time frame: Baseline and 6 months after fixed prosthodontic rehabilitation
Hemoglobin A1c (HbA1c) (%) measured using standard laboratory methods. The mean change in HbA1c from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Change in High-Density Lipoprotein Cholesterol (HDL-C)
Time frame: Baseline and 6 months after fixed prosthodontic rehabilitation
High-density lipoprotein cholesterol (HDL-C) concentration (mg/dL) measured using standard laboratory blood analysis. The mean change in HDL-C from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Change in Low-Density Lipoprotein Cholesterol (LDL-C)
Time frame: Baseline and 6 months after fixed prosthodontic rehabilitation
Low-density lipoprotein cholesterol (LDL-C) concentration (mg/dL) measured using standard laboratory blood analysis. The mean change in LDL-C from baseline to 6 months after fixed prosthodontic rehabilitation will be assessed.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jul 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Fixed Prosthodontic Rehabilitation in people with Ischemic Heart Disease, run by Dr. Moaz Mohamed at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Hemoglobin A1c (HbA1c) (time frame: Baseline and 6 months after fixed prosthodontic rehabilitation). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jul 2026.