HealthyMEDWELLNCT07707414

Impact of a Short-Term Mediterranean-Style Diet on Health Indices

A study testing A mediterranean style diet and Habitual Diet in people with Healthy, run by University of Roehampton at 1 site in United Kingdom.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

Emerging evidence suggests protective properties of a Mediterranean diet (MD) in relation to prevention and management of mood disorders. However, there is paucity of dietary interventions investigating adherence to MD and effects on mood and wellbeing in individuals without a clinical diagnosis. Read more about this study

Who is it for?: Ages 35 to 64 yearsHealthy volunteers can take part
Conditions the study is for: Healthy
What is being tested?: A mediterranean style diet and Habitual Diet
Could I receive a placebo?: Yes, some participants may receive a placebo
How many people: 22 participants
Where: 1 siteUnited Kingdom
Study dates: 1 Mar 2019to 20 Aug 2019
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 35 to 64 years
All sexes
Healthy volunteers accepted
Adult

Who may be able to join

Habitual diet of low Mediterranean Diet (MD)adherence i.e. individuals with MD scoring ≤7 (low adherence) were included.
Living in UK

Who cannot join

pregnant or breastfeeding following a weight loss diet
diagnosed medical condition (diabetes, cardiovascular disease, cancer, food allergies)
have any further health conditions which may cause you to react adversely whilst changing your diet.
diagnosed with a neurological impairment or psychiatric disorder
Current smoker (last 12 months)
history of substance abuse
taking dietary supplements
already following a Mediterranean style diet

Trial locations and contacts

1 site in 1 country.

United Kingdom1 site

University of Roehampton, School of Life and Health Sciences
London, UK, SW15 4JD

Other trials in United Kingdom

About this study

Official title: Exploring the Effects of a Short-term Mediterranean-style Dietary Intervention on Indices of Mood and Wellbeing in UK Adults

Read the detailed description

This is a 1-week, cross-over, randomised, controlled study investigating the effects of Mediterranean style diet on perceived mood and overall wellbeing in healthy adults. The intervention consists following daily for 1 week a Mediterranean style eating pattern. Participants are following their habitual diet during the control week. This is an investigator-initiated, randomised, cross-over, controlled study.

Conditions: Healthy
Being tested: A mediterranean style diet, Habitual Diet

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

A mediterranean style dietOther
Also called MD
At baseline, an Educational Group Session (EGS) introduced participants to the Mediterranean Diet (MD) principles to support adherence. The interactive EGS covered MD typical foods to consume and avoid, cooking methods, and practical shopping guidance. Following the EGS, participants adopted a Mediterranean-style diet for a period of 7 days. Participants were encouraged to follow the MD guidelines (replacing typical western foods with MD foods) without restricting energy intake; examples were provided during the EGS and with take-home resource materials which detailed 'simple swaps' or alternative MD food items to replace western food items.
Habitual DietOther
participants were instructed to follow their habitual diet (control) and eating practices for 7 days. without restricting energy intake.

Study groups in NCT07707414
Study group	Role	What they receive
A Mediterranean style diet	Active comparator	At baseline, participants attended an Educational Group Session (EGS) introducing the principles of the Mediterranean Diet (MD), including recommended foods, foods to limit, cooking methods, and shopping tips. Participants then followed a Mediterranean-style diet for 7 days, replacing typical Western foods with MD alternatives without restricting energy intake. Practical examples and take-home materials with simple food swaps were provided to support adherence. Receives: Other: A mediterranean style diet
Habitual diet	Placebo comparator	Participants were instructed to follow their habitual diet (control) and eating practices for 7 days. without restricting energy intake. Receives: Other: Habitual Diet

What is being measured

The primary outcome is the main question the study is designed to answer.

Mood
Change in mood measured using the Bond-Lader Visual Analogue Scale (VAS). The scale ranges from 0 to 100, with higher scores indicating a more positive mood state (better outcome).
Measured: Baseline and 7 days (final day of each condition) espressed in questionnaire scores

Secondary outcomes (1)

Wellbeing
Change in wellbeing measured using the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS). The WEMWBS total score ranges from 14 to 70, with higher scores indicating greater mental wellbeing (better outcome).
Measured: Baseline and 7 days (final day of each condition) espressed in questionnaire scores

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1 Mar 201920 Aug 2019

First posted16 Jul 2026
Study start1 Mar 2019
Primary completion12 May 2019
Study completion20 Aug 2019

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for HealthyStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Crossover
Model description: a randomised controlled-crossover design was employed, including a washout period to reduce carryover effects. Random allocation determined participants' diet order; counterbalanced to follow the MedDiet (MD) or their habitual diet (Control) for 7 days (week 1). This was followed by a washout (week 2), before participants completed the alternate condition (week 3). This is an investigator-initiated, randomised,controlled pilot study.
Masking: Double blind
Who is masked: Participant, Investigator
Enrolment: 22 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07707414
Sponsor's protocol ID: MED-MOOD-UK-2026-001
Acronym: MEDWELL
Status last verified: Jul 2026
First submitted: 19 Jun 2026
Last updated: 16 Jul 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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Study at a glance

From the registry record, last updated by the sponsor on 16 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Exploring the Effects of a Short-term Mediterranean-style Dietary Intervention on Indices of Mood and Wellbeing in UK Adults
ClinicalTrials.gov ID: NCT07707414
Acronym / sponsor ID: MEDWELL / MED-MOOD-UK-2026-001
Conditions: Healthy
Study type: Interventional
Recruitment status: Completed
Enrolment: 22 participants (actual)
Lead sponsor: University of RoehamptonUniversity, hospital or other
Study start: 1 Mar 2019 (actual)
Primary completion: 12 May 2019 (actual)
Study completion: 20 Aug 2019 (actual)
First posted: 16 Jul 2026 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Crossover
Masking: Double blind (participant, investigator)
Number of arms: 2
Model description: a randomised controlled-crossover design was employed, including a washout period to reduce carryover effects. Random allocation determined participants' diet order; counterbalanced to follow the MedDiet (MD) or their habitual diet (Control) for 7 days (week 1). This was followed by a washout (week 2), before participants completed the alternate condition (week 3). This is an investigator-initiated, randomised,controlled pilot study.

Arm	Type	Receives
A Mediterranean style diet	Active comparator	Other: A mediterranean style dietAt baseline, participants attended an Educational Group Session (EGS) introducing the principles of the Mediterranean Diet (MD), including recommended foods, foods to limit, cooking methods, and shopping tips. Participants then followed a Mediterranean-style diet for 7 days, replacing typical Western foods with MD alternatives without restricting energy intake. Practical examples and take-home materials with simple food swaps were provided to support adherence.
Habitual diet	Placebo comparator	Other: Habitual DietParticipants were instructed to follow their habitual diet (control) and eating practices for 7 days. without restricting energy intake.

Who may qualify

Ages: 35 to 64 years
Sex: All
Healthy volunteers: Accepted
Age groups: Adult

Key inclusion criteria (2 listed)

Habitual diet of low Mediterranean Diet (MD)adherence i.e. individuals with MD scoring ≤7 (low adherence) were included.
Living in UK

Key exclusion criteria (8 listed)

pregnant or breastfeeding following a weight loss diet
diagnosed medical condition (diabetes, cardiovascular disease, cancer, food allergies)
have any further health conditions which may cause you to react adversely whilst changing your diet.
diagnosed with a neurological impairment or psychiatric disorder
Current smoker (last 12 months)

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
A mediterranean style dietAlso: MDAt baseline, an Educational Group Session (EGS) introduced participants to the Mediterranean Diet (MD) principles to support adherence. The interactive EGS covered MD typical foods to consume and avoid, cooking methods, and practical shopping guidance. Following the EGS, participants adopted a Mediterranean-style diet for a period of 7 days. Participants were encouraged to follow the MD guidelines (replacing typical western foods with MD foods) without restricting energy intake; examples were provided during the EGS and with take-home resource materials which detailed 'simple swaps' or alternative MD food items to replace western food items.	Other	A Mediterranean style diet
Habitual Dietparticipants were instructed to follow their habitual diet (control) and eating practices for 7 days. without restricting energy intake.	Other	Habitual diet

Primary outcome

Mood
Time frame: Baseline and 7 days (final day of each condition) espressed in questionnaire scores
Change in mood measured using the Bond-Lader Visual Analogue Scale (VAS). The scale ranges from 0 to 100, with higher scores indicating a more positive mood state (better outcome).

1 secondary outcome

Wellbeing
Time frame: Baseline and 7 days (final day of each condition) espressed in questionnaire scores

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 16 Jul 2026.

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THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS
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A Phase I Study of GLR2053 Tablets in Chinese Healthy Adult Participants
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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Fotini Tsofliou principal investigator

University of Roehampton

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing A mediterranean style diet and Habitual Diet in people with Healthy, run by University of Roehampton at 1 site in United Kingdom.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 16 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Mood (time frame: Baseline and 7 days (final day of each condition) espressed in questionnaire scores). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07707414.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jul 2026.