Overweight or ObesityMomentumNCT07708064
Testing Just-in-Time Adaptive Interventions (JITAIs) to Prevent Goal Disengagement in Response to Weight Regain
A study testing JITAI Combined with psychological intervention in people with Overweight or Obesity, run by ORI Community and Evaluation Services at 1 site in United States.
Trial summary
This trial will test the effectiveness of a weight loss maintenance intervention designed to help participants respond more adaptively to weight regain. Participants will be randomly assigned to one of two conditions. Read more about this study
- Who is it for?
- Ages 18 to 70 years
- Conditions the study is for
- Overweight or Obesity
- What is being tested?
- JITAI Combined with psychological intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 120 participants
- Where
- 1 siteUnited States
- Study dates
- 14 Jul 2026to 31 Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Ages 18-70 years
- BMI of 25-50 kg/m2
- Current weight is 3% lower than their highest weight in the past 3 years
- Desire to maintain their weight or lose more
- Ability to engage in PA, as defined as being able to walk two full city blocks without stopping
- Smartphone and Internet access
- Successful completion of all enrollment procedures
- Ability to attend a workshop(s) on a Monday or Tuesday evening
Who cannot join
- History of bariatric surgery
- History of being diagnosed with an eating disorder
- Currently pregnant, breastfeeding, or planning to become pregnant in the next 24 months
- Enrolled in another formal weight loss/weight maintenance program
- Currently taking a GLP-1 medication.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Oregon Research Institute Community and Evaluation Services
Springfield, Oregon, 97477
Charlotte Hagerman, PhD, 4109372035, chagerman@ori.org
About this study
This trial will test the effectiveness of a weight loss maintenance intervention designed to help participants respond more adaptively to weight regain. Participants will be randomly assigned to one of two conditions. In one condition, participants will receive brief exercises (e.g., written reflections, videos) sent to through a smartphone app immediately after they regain weight or miss a weigh-in. These exercises will use mindfulness, acceptance, and self-compassion strategies to help participants stay motivated for their long term goals, even when weight regain feels demoralizing. In the comparison condition, participants will receive weekly reminders of standard weight control strategies strategies.
- Conditions
- Overweight or Obesity
- Being tested
- JITAI Combined with psychological intervention, Active Control
- Keywords
- just-in-time adaptive interventions, weight regain, self-weighing, self-compassion, acceptance-based behavioral treatments, mindfulness, behavioral weight loss
- Medical subject headings
- Overweight, Obesity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
JITAI Combined with psychological interventionBehavioural
For six months, participants will receive a just-in-time adaptive interventions via a smartphone app immediately after they gain weight or they skip a weigh-in (according to a specific algorithm). Interventions will engage participants in mindfulness, acceptance, and self-compassion-based (MASC) strategies through different modalities (e.g., writing exercises, videos, audio reflections). They will take approximately 1-10 minutes. Participants will also attend an introductory workshop, during which they will receive the instructions weigh daily, learn the importance of quickly responding to weight regain, and be introduced to MASC strategies. They will also attend two booster workshops during the 6-month period.
Active ControlBehavioural
For six months, participants will receive weekly, automated messages via a smartphone app with reminders of standard behavioral weight control principles. Participants will attend an introductory workshop, during which they will receive instructions to weigh daily and learn the importance of responding to weight regain.
| Study group | Role | What they receive |
|---|---|---|
| JITAI Condition | Experimental | Participants in this condition will receive a 6-month weight loss maintenance intervention that uses mindfulness, acceptance, and self-compassion strategies to respond to weight regain. Receives: Behavioral: JITAI Combined with psychological intervention |
| Active Control Condition | Active comparator | Participants in this condition will receive minimal intervention designed to reflect "usual care" for weight loss maintenance. Receives: Behavioral: Active Control |
What is being measured
The primary outcome is the main question the study is designed to answer.
State negative affect
Through ecological assessment surveys, participants will respond to a single item measuring their current negative affect.
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
State shame
Through ecological assessment surveys, participants will respond to a single item measuring their current shame.
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
State Motivation
Through ecological assessment surveys, participants will respond to a single item measuring their current feelings of motivation.
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
State Self-Efficacy
Through ecological assessment surveys, participants will respond to a single item measuring their current self-efficacy.
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Current confidence in the effectiveness of weight control behaviors
Through ecological assessment surveys, participants will respond to a single item measuring their current confidence in the effectiveness of weight control behaviors.
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
State self-compassion
Through ecological assessment surveys, participants will respond to a single item measuring their state self-compassion.
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
State mindfulness
Through ecological assessment surveys, participants will respond to a single item measuring their state mindfulness.
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
State acceptance
Through ecological assessment surveys, participants will respond to a single item measuring their state acceptance.
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Self-serving interpretation of weight gain
Through ecological assessment surveys, participants will respond to a single item measuring their self-serving interpretation of the weight regain.
Measured: Whenever participants regain weight during the 6 month study period
Daily Calorie Tracking (Yes/No)
Whether participants log their calories (at least 800 calories) using a dietary tracking app that day (yes/no).
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Daily MVPA
Minutes of moderate-to-vigorous physical activity they engage in that day, as tracked by their Fitbit band.
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Likelihood of weighing in the following day
Likelihood that participants weigh themselves the following day on a wireless smart scale (yes/no).
Measured: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Weight change
Using participants' weights from a wireless scale, their percent weight change from the beginning to the end of the study period will be calculated.
Measured: End of treatment (6 months after baseline)
Intervention acceptability
Intervention acceptability will be operationalized as the percent of participants who indicate that they are "satisfied" or "very satisfied" with the program on an anonymous survey that they complete during their individual interview.
Measured: End of treatment (6 months after baseline)
Calorie Tracking Frequency
The number of days that participants logged their calories (at least 800 calories) using a dietary tracking app during the study period.
Measured: 6 months (duration of study period)
Average Weekly MVPA
Average total minutes of weekly moderate-to-vigorous physical activity, as tracked by their Fitbit band, during the study period.
Measured: 6 months (duration of study period)
Frequency of Weighing In
Total number of days that participants weighed themselves on a wireless smart scale during the study period.
Measured: 6 months (duration of study period)
Secondary outcomes (3)
Mindfulness (Hypothesized intervention mediator)
Participants will self-report their mindfulness using the Awareness subscale of The Philadelphia Mindfulness Scale. The range of scores is 1-5, with higher scores indicating greater mindfulness.
Measured: Mid-Treatment (3 months after baseline)
Acceptance (Hypothesized intervention mediator)
Participants will self-report their mindful acceptance using the Acceptance subscale of The Philadelphia Mindfulness Scale. The range of scores is 1-5, with higher scores indicating greater mindful acceptance.
Measured: Mid-Treatment (3 months after baseline)
Self-compassion (Hypothesized intervention mediator)
Participants will report their self-compassion using the Self-Compassion Scale Short Form. Scores can range from 1 to 5, with higher scores indicating higher self-compassion.
Measured: Mid-Treatment (3 months after baseline)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jul 2026
- Study start14 Jul 2026
- Primary completion31 Dec 2027 (estimated)
- Study completion31 Dec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Overweight or ObesityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- ORI Community and Evaluation Services
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07708064
- Sponsor's protocol ID
- K01HL172254
- Acronym
- Momentum
- Status last verified
- Aug 2026
- First submitted
- 12 Jul 2026
- Last updated
- 11 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Testing Just-in-Time Adaptive Interventions (JITAIs) to Prevent Goal Disengagement in Response to Weight Regain
- ClinicalTrials.gov ID
- NCT07708064
- Acronym / sponsor ID
- Momentum / K01HL172254
- Conditions
- Overweight or Obesity
- Keywords
- just-in-time adaptive interventions, weight regain, self-weighing, self-compassion, acceptance-based behavioral treatments, mindfulness, behavioral weight loss
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- ORI Community and Evaluation ServicesUniversity, hospital or other
- Study start
- 14 Jul 2026 (actual)
- Primary completion
- 31 Dec 2027 (estimated)
- Study completion
- 31 Dec 2027 (estimated)
- First posted
- 16 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This trial will test the effectiveness of a weight loss maintenance intervention designed to help participants respond more adaptively to weight regain. Participants will be randomly assigned to one of two conditions. In one condition, participants will receive brief exercises (e.g., written reflections, videos) sent to through a smartphone app immediately after they regain weight or miss a weigh-in. These exercises will use mindfulness, acceptance, and self-compassion strategies to help participants stay motivated for their long term goals, even when weight regain feels demoralizing. In the comparison condition, participants will receive weekly reminders of standard weight control strategies strategies.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| JITAI Condition | Experimental | Behavioral: JITAI Combined with psychological interventionParticipants in this condition will receive a 6-month weight loss maintenance intervention that uses mindfulness, acceptance, and self-compassion strategies to respond to weight regain. |
| Active Control Condition | Active comparator | Behavioral: Active ControlParticipants in this condition will receive minimal intervention designed to reflect "usual care" for weight loss maintenance. |
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Ages 18-70 years
- BMI of 25-50 kg/m2
- Current weight is 3% lower than their highest weight in the past 3 years
- Desire to maintain their weight or lose more
- Ability to engage in PA, as defined as being able to walk two full city blocks without stopping
Key exclusion criteria (5 listed)
- History of bariatric surgery
- History of being diagnosed with an eating disorder
- Currently pregnant, breastfeeding, or planning to become pregnant in the next 24 months
- Enrolled in another formal weight loss/weight maintenance program
- Currently taking a GLP-1 medication.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| JITAI Combined with psychological interventionFor six months, participants will receive a just-in-time adaptive interventions via a smartphone app immediately after they gain weight or they skip a weigh-in (according to a specific algorithm). Interventions will engage participants in mindfulness, acceptance, and self-compassion-based (MASC) strategies through different modalities (e.g., writing exercises, videos, audio reflections). They will take approximately 1-10 minutes. Participants will also attend an introductory workshop, during which they will receive the instructions weigh daily, learn the importance of quickly responding to weight regain, and be introduced to MASC strategies. They will also attend two booster workshops during the 6-month period. | Behavioural | JITAI Condition |
| Active ControlFor six months, participants will receive weekly, automated messages via a smartphone app with reminders of standard behavioral weight control principles. Participants will attend an introductory workshop, during which they will receive instructions to weigh daily and learn the importance of responding to weight regain. | Behavioural | Active Control Condition |
Primary outcome
State negative affect
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Through ecological assessment surveys, participants will respond to a single item measuring their current negative affect.
State shame
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Through ecological assessment surveys, participants will respond to a single item measuring their current shame.
State Motivation
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Through ecological assessment surveys, participants will respond to a single item measuring their current feelings of motivation.
State Self-Efficacy
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Through ecological assessment surveys, participants will respond to a single item measuring their current self-efficacy.
Current confidence in the effectiveness of weight control behaviors
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Through ecological assessment surveys, participants will respond to a single item measuring their current confidence in the effectiveness of weight control behaviors.
State self-compassion
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Through ecological assessment surveys, participants will respond to a single item measuring their state self-compassion.
State mindfulness
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Through ecological assessment surveys, participants will respond to a single item measuring their state mindfulness.
State acceptance
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Through ecological assessment surveys, participants will respond to a single item measuring their state acceptance.
Self-serving interpretation of weight gain
Time frame: Whenever participants regain weight during the 6 month study period
Through ecological assessment surveys, participants will respond to a single item measuring their self-serving interpretation of the weight regain.
Daily Calorie Tracking (Yes/No)
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Whether participants log their calories (at least 800 calories) using a dietary tracking app that day (yes/no).
Daily MVPA
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Minutes of moderate-to-vigorous physical activity they engage in that day, as tracked by their Fitbit band.
Likelihood of weighing in the following day
Time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period
Likelihood that participants weigh themselves the following day on a wireless smart scale (yes/no).
Weight change
Time frame: End of treatment (6 months after baseline)
Using participants' weights from a wireless scale, their percent weight change from the beginning to the end of the study period will be calculated.
Intervention acceptability
Time frame: End of treatment (6 months after baseline)
Intervention acceptability will be operationalized as the percent of participants who indicate that they are "satisfied" or "very satisfied" with the program on an anonymous survey that they complete during their individual interview.
Calorie Tracking Frequency
Time frame: 6 months (duration of study period)
The number of days that participants logged their calories (at least 800 calories) using a dietary tracking app during the study period.
Average Weekly MVPA
Time frame: 6 months (duration of study period)
Average total minutes of weekly moderate-to-vigorous physical activity, as tracked by their Fitbit band, during the study period.
Frequency of Weighing In
Time frame: 6 months (duration of study period)
Total number of days that participants weighed themselves on a wireless smart scale during the study period.
3 secondary outcomes
Mindfulness (Hypothesized intervention mediator)
Time frame: Mid-Treatment (3 months after baseline)
Acceptance (Hypothesized intervention mediator)
Time frame: Mid-Treatment (3 months after baseline)
Self-compassion (Hypothesized intervention mediator)
Time frame: Mid-Treatment (3 months after baseline)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing JITAI Combined with psychological intervention in people with Overweight or Obesity, run by ORI Community and Evaluation Services at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 11 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Charlotte Hagerman, PhD (14109372035, chagerman@ori.org), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
State negative affect (time frame: Whenever participants skip a weigh-in or regain weight during the 6 month study period). The study lists 17 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Aug 2026.