Flexor Tendon InjuryNCT07708298
Myofascial Release Versus Hand Mobilization After Flexor Tendon Repair
A study testing Myofascial Release and Hand Mobilization in people with Flexor Tendon Injury, run by Cairo University at 1 site in Egypt.
Trial summary
Flexor tendon repair is commonly performed to restore hand function after tendon injuries. Different rehabilitation techniques are used to improve range of motion, grip strength, and functional outcomes. Read more about this study
- Who is it for?
- Ages 20 to 45 years
- Conditions the study is for
- Flexor Tendon Injury
- What is being tested?
- Myofascial Release and Hand Mobilization
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Apr 2026to 2 Jul 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- The subject selection will be based on the following criteria:
- 20-45years of age
- Post-flexor tendon repair surgery in zone 2 within 2-4 weeks
- Ability to understand and follow study instructions
- Willingness to participate in the rehabilitation program
Who cannot join
- Potential participants will be excluded if they meet one of the following criteria:
- Severe joint deformities or arthritis in the wrist or hand
- Infections or other complications related to the tendon repair
- History of neurological disorders or conditions affecting hand function
- Non-compliance or contraindications to manual therapy
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Faculty of Physical Therapy, Cairo University
Giza, Giza Governorate
About this study
Official title: Hand Mobilization Versus Myofascial Release Following Flexor Tendon Repair
Flexor tendon repair is commonly performed to restore hand function after tendon injuries. Different rehabilitation techniques are used to improve range of motion, grip strength, and functional outcomes. This randomized controlled trial compares the effects of myofascial release and hand mobilization following flexor tendon repair. Thirty participants are randomly allocated into two groups. Outcomes include wrist range of motion, grip strength, and the QuickDASH questionnaire. The findings may help determine the effectiveness of these rehabilitation techniques following flexor tendon repair.
Read the detailed description
This randomized controlled trial aims to compare the effectiveness of myofascial release and hand mobilization following flexor tendon repair.
Thirty participants who underwent flexor tendon repair will be randomly assigned into two equal groups.
Group A will receive a hand mobilization program in addition to the conventional rehabilitation program.
Group B will receive myofascial release in addition to the conventional rehabilitation program.
Treatment will be provided according to the study protocol.
Outcome measures include wrist range of motion (flexion, extension, radial deviation, and ulnar deviation), grip strength measured using a hand dynamometer, and upper limb function assessed using the QuickDASH questionnaire.
Assessments will be performed before treatment and after completion of the rehabilitation program. The study aims to determine whether one intervention provides superior clinical outcomes compared with the other.
- Conditions
- Flexor Tendon Injury
- Being tested
- Myofascial Release, Hand Mobilization
- Keywords
- Flexor tendon repair, Myofascial release, Hand mobilization, Physical therapy, Range of motion, Grip strength, QuickDASH, Hand rehabilitation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Myofascial ReleaseOther
Myofascial release is a manual therapy technique applied after flexor tendon repair as part of the rehabilitation program. The technique aims to improve soft tissue mobility, reduce myofascial restrictions, enhance wrist and hand range of motion, and improve functional outcomes.
Hand MobilizationOther
Hand mobilization is a rehabilitation technique applied after flexor tendon repair to improve tendon gliding, wrist and hand range of motion, and functional recovery.
| Study group | Role | What they receive |
|---|---|---|
| Myofascial Release | Experimental | Participants received myofascial release techniques combined with conventional rehabilitation following flexor tendon repair. Receives: Other: Myofascial Release |
| Hand Mobilization | Experimental | Participants received hand mobilization techniques combined with conventional rehabilitation following flexor tendon repair. Receives: Other: Hand Mobilization |
What is being measured
The primary outcome is the main question the study is designed to answer.
Wrist Range of Motion
Wrist flexion, extension, radial deviation, and ulnar deviation measured using a universal goniometer.
Measured: Baseline (pre-intervention) and 4 weeks
Grip Strength
Grip strength measured using a hand dynamometer.
Measured: Baseline (pre-intervention) and 4 weeks
QuickDASH Score
Upper limb function assessed using the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) questionnaire.
Measured: Baseline (pre-intervention) and 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jul 2026
- Study start1 Apr 2026
- Primary completion1 Jul 2026
- Study completion2 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Flexor Tendon InjuryStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to one of two parallel intervention groups. One group will receive hand mobilization with conventional rehabilitation, while the other group will receive myofascial release with conventional rehabilitation.
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hagar Mohamed Mahmoud Ahmed, Cairo University
- Investigators
- Hussin Gamal Megahed, Professor, Principal investigator, Research Ethical Committee Faculty of Physical Therapy Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07708298
- Sponsor's protocol ID
- CU-PT-2026-001
- Status last verified
- Jul 2026
- First submitted
- 8 Jul 2026
- Last updated
- 16 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Hand Mobilization Versus Myofascial Release Following Flexor Tendon Repair
- ClinicalTrials.gov ID
- NCT07708298
- Acronym / sponsor ID
- CU-PT-2026-001
- Conditions
- Flexor Tendon Injury
- Keywords
- Flexor tendon repair, Myofascial release, Hand mobilization, Physical therapy, Range of motion, Grip strength, QuickDASH, Hand rehabilitation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Apr 2026 (actual)
- Primary completion
- 1 Jul 2026 (actual)
- Study completion
- 2 Jul 2026 (actual)
- First posted
- 16 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Flexor tendon repair is commonly performed to restore hand function after tendon injuries. Different rehabilitation techniques are used to improve range of motion, grip strength, and functional outcomes. This randomized controlled trial compares the effects of myofascial release and hand mobilization following flexor tendon repair. Thirty participants are randomly allocated into two groups. Outcomes include wrist range of motion, grip strength, and the QuickDASH questionnaire. The findings may help determine the effectiveness of these rehabilitation techniques following flexor tendon repair.
Detailed description
This randomized controlled trial aims to compare the effectiveness of myofascial release and hand mobilization following flexor tendon repair.
Thirty participants who underwent flexor tendon repair will be randomly assigned into two equal groups.
Group A will receive a hand mobilization program in addition to the conventional rehabilitation program.
Group B will receive myofascial release in addition to the conventional rehabilitation program.
Treatment will be provided according to the study protocol.
Outcome measures include wrist range of motion (flexion, extension, radial deviation, and ulnar deviation), grip strength measured using a hand dynamometer, and upper limb function assessed using the QuickDASH questionnaire.
Assessments will be performed before treatment and after completion of the rehabilitation program. The study aims to determine whether one intervention provides superior clinical outcomes compared with the other.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to one of two parallel intervention groups. One group will receive hand mobilization with conventional rehabilitation, while the other group will receive myofascial release with conventional rehabilitation.
| Arm | Type | Receives |
|---|---|---|
| Myofascial Release | Experimental | Other: Myofascial ReleaseParticipants received myofascial release techniques combined with conventional rehabilitation following flexor tendon repair. |
| Hand Mobilization | Experimental | Other: Hand MobilizationParticipants received hand mobilization techniques combined with conventional rehabilitation following flexor tendon repair. |
Who may qualify
- Ages
- 20 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- The subject selection will be based on the following criteria:
Key exclusion criteria (5 listed)
- Potential participants will be excluded if they meet one of the following criteria:
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Myofascial ReleaseMyofascial release is a manual therapy technique applied after flexor tendon repair as part of the rehabilitation program. The technique aims to improve soft tissue mobility, reduce myofascial restrictions, enhance wrist and hand range of motion, and improve functional outcomes. | Other | Myofascial Release |
| Hand MobilizationHand mobilization is a rehabilitation technique applied after flexor tendon repair to improve tendon gliding, wrist and hand range of motion, and functional recovery. | Other | Hand Mobilization |
Primary outcome
Wrist Range of Motion
Time frame: Baseline (pre-intervention) and 4 weeks
Wrist flexion, extension, radial deviation, and ulnar deviation measured using a universal goniometer.
Grip Strength
Time frame: Baseline (pre-intervention) and 4 weeks
Grip strength measured using a hand dynamometer.
QuickDASH Score
Time frame: Baseline (pre-intervention) and 4 weeks
Upper limb function assessed using the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) questionnaire.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jul 2026.
- Individual participant dataSharing planned: No
Related trials for Flexor Tendon Injury
Not yet recruiting
Study Evaluating the Safety and Efficacy of the TMChM Prosthesis in the Treatment of People With Chronic Flexor Tendon Fingers Injuries
Tendon Injuries
Recruiting
Ultrasound-Guided Repeated Saline Injections to Prevent and Treat Tendon Adhesions After Hand Tendon Repair
Tendon Adhesion, Zone II Flexor Tendon Injury
Recruiting
Virtual Reality Combined With Active Mobilization Post Flexor Tendon Repair
Flexor Tendon Injury
Recruiting
Effects of Different Wrist Positions in Dorsal Blocking Orthoses After Flexor Tendon Repair
Flexor Tendon Injury, Tendon Injury - Hand
Recruiting
Registry-randomized Comparison of Rehabilitation Regimens After Flexor Tendon Injury in the Thumb
Flexor Tendon Injury, Rehabilitation Program
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Hussin Gamal Megahed, Professor principal investigator
Research Ethical Committee Faculty of Physical Therapy Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Myofascial Release and Hand Mobilization in people with Flexor Tendon Injury, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Wrist Range of Motion (time frame: Baseline (pre-intervention) and 4 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jul 2026.