COPD (Chronic Obstructive Pulmonary Disease)NCT07719192
Effects of Alternate Nostril Breathing and Bellows Breath in COPD Patients
A study testing alternate nostril breathing and bellows breath in people with COPD (Chronic Obstructive Pulmonary Disease), run by Riphah International University at 1 site in Pakistan.
Trial summary
COPD is a common respiratory disease characterized by progressive airflow obstruction, dyspnea, chronic cough, and sputum production. Alternate nostril breathing and bellows breath are pranayama-based breathing techniques that may improve respiratory function and overall well-being. Read more about this study
- Who is it for?
- Ages 10 years and older
- Conditions the study is for
- COPD (Chronic Obstructive Pulmonary Disease)
- What is being tested?
- alternate nostril breathing and bellows breath
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 54 participants
- Where
- 1 sitePakistan
- Study dates
- Jun 2026to 1 Aug 2026
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 years and older
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- diagnosed case of copd patients
- Age group:above 10 years
- Clinically stable
- Able to understand or perform breathing exercise
Who cannot join
- current acute pulmonary infection
- History of pneumothorax or hemoptysis
- Patients who was in stage 4 of functional classification of fatigue,palpation,dyspnea or anginal pain
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site
Nimra Noor
Lahore, Punjab Province, 40100
Nimra Noor Nimra Noor, MS-CPPT, 03030684869, nimranoor358@gmail.com
Nimra Noor, MS-CPPT
About this study
Official title: Effects of Alternate Nostril Breathing and Bellows Breath on Sputum Clearance, Pulmonary Function Test and Quality of Life Among COPD Patients
COPD is a common respiratory disease characterized by progressive airflow obstruction, dyspnea, chronic cough, and sputum production. Alternate nostril breathing and bellows breath are pranayama-based breathing techniques that may improve respiratory function and overall well-being. This randomized clinical trial aims to compare the effects of these techniques on sputum clearance, pulmonary function tests, and quality of life in COPD patients. The study will be conducted at Punjab Institute of Cardiology using convenient sampling. Participants will be divided into two groups: Group A will perform alternate nostril breathing, while Group B will perform bellows breath exercises for 15-20 minutes daily over 3-4 weeks. Outcome measures include sputum clearance, spirometry, and quality of life questionnaires. Data will be analyzed using SPSS with significance set at p < 0.05. The study may support the use of cost-effective, noninvasive breathing techniques for improving pulmonary function and quality of life in COPD patients.
Read the detailed description
The respiratory ailment known as chronic obstructive pulmonary disease (COPD) is becoming more and more common all over the world. It is characterized by a partiallyvolatile airway blockage. It is characterized by growing and ongoing dyspnea, persistent coughing and sputum production. Chronic cough and sputumare separaterisk factors for early death from COPD, and they are often closely associated withexacerbation. Alternate nostril breathing and bellows breath are two commontechnique which is based on pranyama,which is yogic practice of breath control. These techniques is utilize specific breathing pattern to in fluence the nervous system,energy flow and overall well being. The objective of this study is to findtheeffect of alternate nostril breathing and bellows breath on sputumclearance,pulmonary function test and quality of life among COPD patients. The study design will be randomized clinical trial. It will conducted at Punjab instituteof cardiology.sample size will be conducted through non-probability convenient sampling as per inclusion criteria participants will be randomly added intotwogroups. . Group A[alternate nostril breathing] and Group B[bellows breath]. bothintervention will be performed for 15 to 20 min/day for 3 to 4 weeks. Pre andpost intervention data will be collected. Outcome measures include sputumclearance,spiromter and health related quality of life questionnaire. Data will beanalyzed by using SPSS. Paired or Independent t-test will be used to comparevariables between the two groups and within the two groups, with significance set at p< 0.05. This study will provide evidence for the integration of noninvasive, cost effective strategies for the enhancement of PFT's and functional capacity and qualityof life.
- Being tested
- alternate nostril breathing, bellows breath
- Keywords
- Alternate nostril breathing, Bellows breath, COPD, Sputum clearance
- Medical subject headings
- Pulmonary Disease, Chronic Obstructive
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
alternate nostril breathingOther
This technique includingstress reduction,improved respiratory health and enhanced mental clarity. Participants will then be instructed to perform this activity 15 to 20 min/day for 4 days/week for 3to 4 weeks.
bellows breathOther
This technique drain the excess phlegm from brain. It improves awareness, focus concentration and productivity. Participants will then be instructed to performthis activity 10 to 15 min/day for 5 days/week for 3 to 4 weeks.
| Study group | Role | What they receive |
|---|---|---|
| Alternate Nostril Breathing | Experimental | This group receive alternate nostril breathing technique. This technique includingstress reduction,improved respiratory health and enhanced mental clarity. Participants will then be instructed to perform this activity 15 to 20 min/day for 4 days/week for 3to 4 weeks. Receives: Other: alternate nostril breathing |
| bellows breath | Experimental | This technique drain the excess phlegm from brain. It improves awareness, focus concentration and productivity. Participants will then be instructed to performthis activity 10 to 15 min/day for 5 days/week for 3 to 4 weeks. Receives: Other: bellows breath |
What is being measured
The primary outcome is the main question the study is designed to answer.
Forced Vital Capacity
Forced Vital Capacity (FVC) will be measured in liters (L) using spirometry. FVC represents the maximum volume of air that can be forcefully exhaled after a maximal inspiration.
Measured: Baseline and after 4 weeks of intervention
Forced Expiratory Volume in One Second
Forced Expiratory Volume in One Second (FEV₁) will be measured in liters (L) using spirometry. FEV₁ represents the volume of air exhaled during the first second of a forced expiratory maneuver.
Measured: Baseline and after 4 weeks of intervention
FEV₁/FVC ratio
The FEV₁/FVC ratio will be expressed as a percentage (%) and calculated from spirometric measurements to assess the degree of airflow limitation
Measured: Baseline and after 4 weeks of intervention
Health-Related Quality of Life
The HRQOL (Health-Related Quality of Life) questionnaire is a tool usedtoassess an individual's overall well-being, focusing on how their health impacts their daily life. It's a 14-item questionnaire developed by the Centers for DiseaseControl and Prevention (CDC) that explores physical, mental, and social healthdomains
Measured: Baseline and after 4 weeks of intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jul 2026
- Study startJun 2026 (estimated)
- Primary completion1 Aug 2026 (estimated)
- Study completion1 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for COPD (Chronic Obstructive Pulmonary Disease)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- as per inclusion criteria participants will be randomly added intotwogroups. . Group A\[alternate nostril breathing\] and Group B\[bellows breath\]. bothintervention will be performed for 15 to 20 min/day for 3 to 4 weeks. Pre andpost intervention data will be collected. Outcome measures include sputumclearance,spiromter and health related quality of life questionnaire. Data will beanalyzed by using SPSS
- Masking
- None (open label)
- Enrolment
- 54 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Arjumand Bano, MS, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07719192
- Sponsor's protocol ID
- REC/RCR & AHS/25/0310
- Status last verified
- Jul 2026
- First submitted
- 8 Jun 2026
- Last updated
- 22 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No