Knee Osteoarthritis (OA)SMART-TKANCT07722559
Manual Traction and Rehabilitation After Knee Replacement Surgery
A study testing Manual Tibiofemoral Traction in people with Knee Osteoarthritis (OA) and Total Knee Arthroplasty (TKA), run by Alma Mater Europaea - Slovenia at 1 site in Kosovo.
Trial summary
The goal of this clinical trial is to determine whether the addition of manual traction to a standard rehabilitation protocol improves early recovery after primary total knee arthroplasty (TKA) in women aged 50-75 years with knee osteoarthritis. Read more about this study
- Who is it for?
- Ages 50 to 75 years, women only
- Conditions the study is for
- Knee Osteoarthritis (OA), Total Knee Arthroplasty (TKA)
- What is being tested?
- Manual Tibiofemoral Traction
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 48 participants
- Where
- 1 siteKosovo
- Study dates
- 22 Jul 2026to 12 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 75 years
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Female patients aged between 50 and 75 years.
- Patients who will undergo primary total knee arthroplasty due to osteoarthritis, classified as Kellgren-Lawrence grades 3 to 4.
- Patients willing to participate in the study and able to provide informed consent.
Who cannot join
- Morbid obesity, defined as a body mass index (BMI) greater than 40 kg/m².
- Revision arthroplasty procedures.
- Presence of severe cardiac, vascular, renal, neurological, psychiatric, or other orthopedic conditions affecting the lower limb and limiting functional abilities.
- Active infections or contraindications to physical therapy.
- Inability to comply with the prescribed rehabilitation protocol.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Kosovo1 site
University Clinical Center of Kosovo (UCCK) - Clinic of Physical Medicine and Rehabilitation
Pristina, Pristina District, 10000
MIMOZE ZOGAJ, MSc, +38344795907, mimoze.zogaj1@almamater.si
MIMOZE ZOGAJ, MSc
About this study
Official title: The Short-Term Impact of Manual Traction Combined With Standard Rehabilitation Protocol on Pain, Function, and Quality of Life After Total Knee Arthroplasty
The goal of this clinical trial is to determine whether the addition of manual traction to a standard rehabilitation protocol improves early recovery after primary total knee arthroplasty (TKA) in women aged 50-75 years with knee osteoarthritis.
The main questions it aims to answer are:
Read more
- Does the addition of manual traction reduce postoperative pain during the first four weeks after TKA?
- Does manual traction improve physical function, knee range of motion, patient-reported knee function, and health-related quality of life compared with standard rehabilitation alone?
- Does manual traction reduce the need for analgesic medication during the early postoperative rehabilitation period?
Researchers will compare participants receiving manual traction plus standard rehabilitation with participants receiving sham traction plus the same standard rehabilitation protocol to determine whether manual traction provides additional clinical benefits during early rehabilitation after TKA.
Participants will:
- Be randomly assigned to either the manual traction group or the sham traction (control) group.
- Receive a standardized rehabilitation program for four weeks after surgery, with the intervention group receiving manual traction and the control group receiving sham traction.
- Attend supervised rehabilitation sessions five times per week throughout the four-week intervention period.
- Complete validated questionnaires assessing pain, knee function, joint awareness, and health-related quality of life at predefined assessment time points.
- Undergo standardized clinical assessments of knee range of motion and physical function before surgery, before rehabilitation, during follow-up, and one month after surgery.
- Have their analgesic medication use recorded throughout the rehabilitation period.
Read the detailed description
Total knee arthroplasty (TKA) is one of the most effective surgical procedures for managing end-stage knee osteoarthritis. Despite advances in surgical techniques and postoperative care, many patients continue to experience pain, reduced range of motion, impaired physical function, and delayed recovery during the early postoperative period. Early rehabilitation is therefore essential to optimize functional outcomes, promote independence, and improve health-related quality of life.
Standard rehabilitation following TKA typically includes pain management, therapeutic exercises, gait training, progressive weight-bearing, and functional mobility training. Although these interventions are effective, additional manual therapy techniques may further enhance postoperative recovery by reducing pain, improving joint mobility, and facilitating functional performance.
Manual traction is a passive joint distraction technique designed to decrease compressive forces across the tibiofemoral joint, improve joint mobility, and reduce pain. While manual traction has demonstrated beneficial effects in patients with knee osteoarthritis and other musculoskeletal disorders, evidence regarding its effectiveness during the early rehabilitation period after TKA remains limited. High-quality randomized controlled trials investigating this intervention in the postoperative setting are scarce.
This randomized, double-blind, sham-controlled clinical trial aims to evaluate the effectiveness of adding manual traction to a standardized rehabilitation protocol during the first four postoperative weeks following primary TKA. Participants will be randomly allocated to receive either manual traction combined with standard rehabilitation or sham traction combined with the same rehabilitation program. Participant and outcome assessor blinding will be implemented to minimize performance and assessment bias, while the treating physiotherapist will not participate in outcome assessment because blinding of the therapist is not feasible.
Detailed Description - The study is designed to determine whether the addition of manual traction provides clinically meaningful improvements during early postoperative recovery. The findings are expected to provide evidence regarding the effectiveness of manual traction as an adjunct to standard rehabilitation and may contribute to the optimization of postoperative physiotherapy protocols following primary total knee arthroplasty.
- Being tested
- Manual Tibiofemoral Traction, Sham Tibiofemoral Traction
- Keywords
- Manual Traction, Quality of life, Early rehabilitation, Standard Rehabilitation protocol, Total Knee Arthroplasty, Pain, Function
- Medical subject headings
- Osteoarthritis, Knee, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Manual Tibiofemoral TractionProcedure or surgery
Participants will receive manual tibiofemoral traction combined with a standardized rehabilitation program following total knee arthroplasty. During the first postoperative week, all participants will receive standard rehabilitation without traction. Manual traction will begin in the second postoperative week and will be applied by a physiotherapist using the Kaltenborn technique. The distal femur will be stabilized with a fixation belt, while a separate traction belt around the distal tibia and fibula will apply tibiofemoral traction with the knee in extension. Traction will progress over three weeks: Grade I in week 2 (10-15% body weight), Grade II in week 3 (15-20%), and Grade III in week 4 (20-25%). The traction grade and force will be adjusted according to patient tolerance and postoperative safety. Each session will include 30-60 seconds of traction followed by a 15-second rest interval, repeated for eight cycles. After each session, ROM (20 active,20 assisted) will be performed.
Sham Tibiofemoral TractionProcedure or surgery
Participants assigned to the control group will receive sham tibiofemoral traction combined with the standardized rehabilitation program following total knee arthroplasty. Sham traction will simulate the manual traction procedure without the application of therapeutic traction force. The procedure will be performed to maintain participant blinding while providing the same rehabilitation protocol as the intervention group.
| Study group | Role | What they receive |
|---|---|---|
| Traction Group (TG) | Experimental | Participants assigned to this arm will receive manual tibiofemoral traction combined with a standardized rehabilitation program following total knee arthroplasty. Manual traction will be applied by a licensed physiotherapist using the Kaltenborn mobilization technique for three weeks, with progressive traction grades and force adjusted according to the study protocol and patient tolerance. The standardized rehabilitation program will include supervised therapeutic exercises targeting pain reduction, improvement of knee range of motion, muscle strength, functional mobility, gait, and overall postoperative recovery. Receives: Procedure: Manual Tibiofemoral Traction |
| Control Group (CG) | Sham comparator | Participants assigned to this arm will receive sham tibiofemoral traction combined with the same standardized rehabilitation program following total knee arthroplasty. Sham traction will replicate the positioning and therapist contact of the manual traction procedure without the application of therapeutic traction force, in order to maintain participant blinding. The standardized rehabilitation program will include supervised therapeutic exercises identical to those provided to the intervention group, targeting pain management, knee range of motion, muscle strength, functional mobility, gait, and postoperative recovery. Receives: Procedure: Sham Tibiofemoral Traction |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Intensity Measured by the Numeric Pain Rating Scale (NPRS)
Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable. Higher scores indicate worse pain.
Measured: Baseline (preoperative) and weekly during the first four postoperative weeks (5 assessments).
Secondary outcomes (8)
Physical Function Measured by the Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS-JR)
Physical function will be assessed using the Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS-JR), a 7-item questionnaire. The raw score (0-28) is converted to a normalized score ranging from 0 to 100, where 0 indicates extreme knee-related problems and 100 indicates optimal knee health. Higher scores indicate better knee function.
Measured: Pre-treatment and at the fourth postoperative week.
Knee range of motion
Knee range of motion will be measured in degrees using a universal goniometer. Higher values indicate greater knee joint mobility and better functional outcome.
Measured: Baseline (preoperative), pre-treatment, and at the fourth postoperative week.
Timed Up and Go Test (TUG)
Functional mobility will be assessed using the Timed Up and Go (TUG) test. The time required to stand up from a chair, walk 3 meters, turn, return, and sit down will be recorded in seconds. Lower times indicate better functional mobility.
Measured: At the fourth postoperative week.
Joint Perception Measured by the Forgotten Joint Score-12 (FJS-12)
Joint perception will be assessed using the Forgotten Joint Score-12 (FJS-12), a 12-item questionnaire. Raw scores are converted to a 0-100 scale, where 0 indicates the greatest joint awareness and 100 indicates complete joint awareness forgetting. Higher scores indicate better joint perception and less awareness of the operated knee during daily activities.
Measured: At 4 weeks after surgery.
Health-Related Quality of Life Measured by the EuroQol 5-Dimension 5-Level Questionnaire (EQ-5D-5L)
Health-related quality of life will be assessed using the EuroQol 5-Dimension 5-Level Questionnaire (EQ-5D-5L). The questionnaire evaluates five dimensions of health: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. The EQ Visual Analogue Scale (EQ-VAS) ranges from 0 to 100, where 0 indicates the worst imaginable health state and 100 indicates the best imaginable health state. Higher scores indicate better health-related quality of life.
Measured: Before surgery (baseline) and at 4 weeks after surgery.
Two-Minute Walk Test (2MWT)
Functional walking capacity will be assessed using the Two-Minute Walk Test (2MWT). The total distance walked in 2 minutes will be recorded in meters. Higher distances indicate better walking capacity.
Measured: At 4 weeks after surgery.
Single-Leg Stance Test (SLST)
Balance will be assessed using the Single-Leg Stance Test (SLST). The duration participants are able to maintain single-leg stance will be recorded in seconds. Longer times indicate better balance.
Measured: At 4 weeks after surgery.
Five Times Sit-to-Stand Test (5xSTS)
Lower limb functional performance will be assessed using the Five Times Sit-to-Stand Test (5xSTS). The time required to complete five consecutive sit-to-stand repetitions will be recorded in seconds. Lower times indicate better lower limb functional performance.
Measured: At 4 weeks after surgery.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jul 2026
- Study start22 Jul 2026 (estimated)
- Primary completion22 Oct 2026 (estimated)
- Study completion12 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee Osteoarthritis (OA)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned in a 1:1 ratio to one of two parallel groups. The intervention group will receive manual tibiofemoral traction combined with a standardized rehabilitation protocol, while the control group will receive sham traction combined with the same standardized rehabilitation protocol. Participants and outcome assessors will be blinded to group allocation; however, the treating physiotherapist cannot be blinded due to the nature of the intervention. The intervention will be administered over a three-week period, and outcomes will be assessed according to the predefined study schedule.
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 48 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Alma Mater Europaea - Slovenia
- Sponsor type
- University, hospital or other
- Collaborators
- University Clinical Centre of Kosova, Royal Medical Hospital LLC.
- Responsible party
- Principal investigator, Mimozë Zogaj, Alma Mater Europaea - Slovenia
- Investigators
- MIMOZE ZOGAJ, MSc, Principal investigator, Alma Mater Europaea - Slovenia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07722559
- Sponsor's protocol ID
- SMART-TKA-281
- Acronym
- SMART-TKA
- Status last verified
- Jul 2026
- First submitted
- 16 Jul 2026
- Last updated
- 23 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) will not be shared because the study involves identifiable clinical data collected from human participants. Data will be protected to ensure participant confidentiality and privacy in accordance with ethical approval requirements and applicable data protection regulations. Only aggregated, de-identified study results will be reported in scientific publications.
Study at a glance
From the registry record, last updated by the sponsor on 23 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Short-Term Impact of Manual Traction Combined With Standard Rehabilitation Protocol on Pain, Function, and Quality of Life After Total Knee Arthroplasty
- ClinicalTrials.gov ID
- NCT07722559
- Acronym / sponsor ID
- SMART-TKA / SMART-TKA-281
- Keywords
- Manual Traction, Quality of life, Early rehabilitation, Standard Rehabilitation protocol, Total Knee Arthroplasty, Pain, Function
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 48 participants (estimated)
- Lead sponsor
- Alma Mater Europaea - SloveniaUniversity, hospital or other
- Collaborators
- University Clinical Centre of Kosova, Royal Medical Hospital LLC.
- Study start
- 22 Jul 2026 (estimated)
- Primary completion
- 22 Oct 2026 (estimated)
- Study completion
- 12 Nov 2026 (estimated)
- First posted
- 23 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to determine whether the addition of manual traction to a standard rehabilitation protocol improves early recovery after primary total knee arthroplasty (TKA) in women aged 50-75 years with knee osteoarthritis.
The main questions it aims to answer are:
- Does the addition of manual traction reduce postoperative pain during the first four weeks after TKA?
- Does manual traction improve physical function, knee range of motion, patient-reported knee function, and health-related quality of life compared with standard rehabilitation alone?
- Does manual traction reduce the need for analgesic medication during the early postoperative rehabilitation period?
Researchers will compare participants receiving manual traction plus standard rehabilitation with participants receiving sham traction plus the same standard rehabilitation protocol to determine whether manual traction provides additional clinical benefits during early rehabilitation after TKA.
Participants will:
- Be randomly assigned to either the manual traction group or the sham traction (control) group.
- Receive a standardized rehabilitation program for four weeks after surgery, with the intervention group receiving manual traction and the control group receiving sham traction.
- Attend supervised rehabilitation sessions five times per week throughout the four-week intervention period.
- Complete validated questionnaires assessing pain, knee function, joint awareness, and health-related quality of life at predefined assessment time points.
- Undergo standardized clinical assessments of knee range of motion and physical function before surgery, before rehabilitation, during follow-up, and one month after surgery.
- Have their analgesic medication use recorded throughout the rehabilitation period.
Detailed description
Total knee arthroplasty (TKA) is one of the most effective surgical procedures for managing end-stage knee osteoarthritis. Despite advances in surgical techniques and postoperative care, many patients continue to experience pain, reduced range of motion, impaired physical function, and delayed recovery during the early postoperative period. Early rehabilitation is therefore essential to optimize functional outcomes, promote independence, and improve health-related quality of life.
Standard rehabilitation following TKA typically includes pain management, therapeutic exercises, gait training, progressive weight-bearing, and functional mobility training. Although these interventions are effective, additional manual therapy techniques may further enhance postoperative recovery by reducing pain, improving joint mobility, and facilitating functional performance.
Manual traction is a passive joint distraction technique designed to decrease compressive forces across the tibiofemoral joint, improve joint mobility, and reduce pain. While manual traction has demonstrated beneficial effects in patients with knee osteoarthritis and other musculoskeletal disorders, evidence regarding its effectiveness during the early rehabilitation period after TKA remains limited. High-quality randomized controlled trials investigating this intervention in the postoperative setting are scarce.
This randomized, double-blind, sham-controlled clinical trial aims to evaluate the effectiveness of adding manual traction to a standardized rehabilitation protocol during the first four postoperative weeks following primary TKA. Participants will be randomly allocated to receive either manual traction combined with standard rehabilitation or sham traction combined with the same rehabilitation program. Participant and outcome assessor blinding will be implemented to minimize performance and assessment bias, while the treating physiotherapist will not participate in outcome assessment because blinding of the therapist is not feasible.
Detailed Description - The study is designed to determine whether the addition of manual traction provides clinically meaningful improvements during early postoperative recovery. The findings are expected to provide evidence regarding the effectiveness of manual traction as an adjunct to standard rehabilitation and may contribute to the optimization of postoperative physiotherapy protocols following primary total knee arthroplasty.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned in a 1:1 ratio to one of two parallel groups. The intervention group will receive manual tibiofemoral traction combined with a standardized rehabilitation protocol, while the control group will receive sham traction combined with the same standardized rehabilitation protocol. Participants and outcome assessors will be blinded to group allocation; however, the treating physiotherapist cannot be blinded due to the nature of the intervention. The intervention will be administered over a three-week period, and outcomes will be assessed according to the predefined study schedule.
| Arm | Type | Receives |
|---|---|---|
| Traction Group (TG) | Experimental | Procedure: Manual Tibiofemoral TractionParticipants assigned to this arm will receive manual tibiofemoral traction combined with a standardized rehabilitation program following total knee arthroplasty. Manual traction will be applied by a licensed physiotherapist using the Kaltenborn mobilization technique for three weeks, with progressive traction grades and force adjusted according to the study protocol and patient tolerance. The standardized rehabilitation program will include supervised therapeutic exercises targeting pain reduction, improvement of knee range of motion, muscle strength, functional mobility, gait, and overall postoperative recovery. |
| Control Group (CG) | Sham comparator | Procedure: Sham Tibiofemoral TractionParticipants assigned to this arm will receive sham tibiofemoral traction combined with the same standardized rehabilitation program following total knee arthroplasty. Sham traction will replicate the positioning and therapist contact of the manual traction procedure without the application of therapeutic traction force, in order to maintain participant blinding. The standardized rehabilitation program will include supervised therapeutic exercises identical to those provided to the intervention group, targeting pain management, knee range of motion, muscle strength, functional mobility, gait, and postoperative recovery. |
Who may qualify
- Ages
- 50 to 75 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Female patients aged between 50 and 75 years.
- Patients who will undergo primary total knee arthroplasty due to osteoarthritis, classified as Kellgren-Lawrence grades 3 to 4.
- Patients willing to participate in the study and able to provide informed consent.
Key exclusion criteria (5 listed)
- Morbid obesity, defined as a body mass index (BMI) greater than 40 kg/m².
- Revision arthroplasty procedures.
- Presence of severe cardiac, vascular, renal, neurological, psychiatric, or other orthopedic conditions affecting the lower limb and limiting functional abilities.
- Active infections or contraindications to physical therapy.
- Inability to comply with the prescribed rehabilitation protocol.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Manual Tibiofemoral TractionParticipants will receive manual tibiofemoral traction combined with a standardized rehabilitation program following total knee arthroplasty. During the first postoperative week, all participants will receive standard rehabilitation without traction. Manual traction will begin in the second postoperative week and will be applied by a physiotherapist using the Kaltenborn technique. The distal femur will be stabilized with a fixation belt, while a separate traction belt around the distal tibia and fibula will apply tibiofemoral traction with the knee in extension. Traction will progress over three weeks: Grade I in week 2 (10-15% body weight), Grade II in week 3 (15-20%), and Grade III in week 4 (20-25%). The traction grade and force will be adjusted according to patient tolerance and postoperative safety. Each session will include 30-60 seconds of traction followed by a 15-second rest interval, repeated for eight cycles. After each session, ROM (20 active,20 assisted) will be performed. | Procedure or surgery | Traction Group (TG) |
| Sham Tibiofemoral TractionParticipants assigned to the control group will receive sham tibiofemoral traction combined with the standardized rehabilitation program following total knee arthroplasty. Sham traction will simulate the manual traction procedure without the application of therapeutic traction force. The procedure will be performed to maintain participant blinding while providing the same rehabilitation protocol as the intervention group. | Procedure or surgery | Control Group (CG) |
Primary outcome
Pain Intensity Measured by the Numeric Pain Rating Scale (NPRS)
Time frame: Baseline (preoperative) and weekly during the first four postoperative weeks (5 assessments).
Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable. Higher scores indicate worse pain.
8 secondary outcomes
Physical Function Measured by the Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS-JR)
Time frame: Pre-treatment and at the fourth postoperative week.
Knee range of motion
Time frame: Baseline (preoperative), pre-treatment, and at the fourth postoperative week.
Timed Up and Go Test (TUG)
Time frame: At the fourth postoperative week.
Joint Perception Measured by the Forgotten Joint Score-12 (FJS-12)
Time frame: At 4 weeks after surgery.
Health-Related Quality of Life Measured by the EuroQol 5-Dimension 5-Level Questionnaire (EQ-5D-5L)
Time frame: Before surgery (baseline) and at 4 weeks after surgery.
Two-Minute Walk Test (2MWT)
Time frame: At 4 weeks after surgery.
Single-Leg Stance Test (SLST)
Time frame: At 4 weeks after surgery.
Five Times Sit-to-Stand Test (5xSTS)
Time frame: At 4 weeks after surgery.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jul 2026.
- Individual participant dataSharing planned: No. Individual participant data (IPD) will not be shared because the study involves identifiable clinical data collected from human participants. Data will be protected to ensure participant confidentiality and privacy in accordance with ethical approval requirements and applicable data protection regulations. Only aggregated, de-identified study results will be reported in scientific publications.
Related trials for Knee Osteoarthritis (OA)
Not yet recruiting
Opioid Reduction and Enhanced Recovery in Orthopaedic Surgery (OREOS)-Knee
Knee Arthroplasty, Total, Partial Knee Arthroplasty
RecruitingPhase 4
Personalized Analgesia Through Central Nervous System Engagement to Unlock Performance
Knee Osteoarthritis (Knee OA), Chronic Pain
Enrolling by invitation
Whole-body Vibration Training on the Elderly With Combined Bilateral Knee Osteoarthritis
Knee OA, Sarcopenic Obesity
Recruiting
Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal
Lower-limb Orthoses, Osteoarthritic Knee Pain
Not yet recruiting
Evaluation of the Effects of Pulsed Electromagnetic Field on Inflammatory Knee Osteoarthritis
Knee Osteoarthritis (Knee OA)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
MIMOZE ZOGAJ, MSc principal investigator
Alma Mater Europaea - Slovenia
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Manual Tibiofemoral Traction in people with Knee Osteoarthritis (OA) and Total Knee Arthroplasty (TKA), run by Alma Mater Europaea - Slovenia at 1 site in Kosovo.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 23 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Kosovo. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact MIMOZE ZOGAJ, MSc (+38344795907, mimoze.zogaj1@almamater.si), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Intensity Measured by the Numeric Pain Rating Scale (NPRS) (time frame: Baseline (preoperative) and weekly during the first four postoperative weeks (5 assessments).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jul 2026; AzTrials last refreshed its copy on 26 Oct 2026.