Distal Radius FractureWBV-DRFNCT07723456

Effect of Whole Body Vibration on Rehabilitation in Distal Radius Fractures

A study testing Whole-Body Vibration Therapy and Conventional Rehabilitation Exercise Program in people with Distal Radius Fracture, run by Istanbul University.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Official record

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Trial summary

Who is it for?: Ages 18 to 65 years
Conditions the study is for: Distal Radius Fracture
What is being tested?: Whole-Body Vibration Therapy and Conventional Rehabilitation Exercise Program
Type of treatment: Medical device
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 66 participants
Where: No sites listed yet
Study dates: 25 Jul 2026to 25 May 2027
Phase: Interventional

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 65 years
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Adults aged 18 to 65 years.
Unilateral distal radius fracture treated conservatively with cast or splint.
Completion of the immobilization period with radiologically confirmed stable callus formation.
Referred for physiotherapy after conservative treatment.
Able to understand study procedures and provide written informed consent.
Initiation of rehabilitation within 72 hours after cast removal.

Who cannot join

Previous surgery or severe trauma to the affected upper extremity.
Open wound or active infection at the fracture site.
Peripheral neuropathy or severe neurological disorders.
Vestibular disorders or conditions contraindicating whole-body vibration therapy.
Pregnancy.
Severe osteoporosis.

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Active inflammatory or vascular disease affecting the upper extremity.
Cognitive impairment preventing participation in the study.
Inability to attend the rehabilitation program regularly.

About this study

Official title: Effect Of Whole Body Vibration On Functional And Sensorimotor Recovery In Conservatively Treated Distal Radius Fractures: A Randomized Controlled Trial

This study is a randomized controlled clinical trial designed to evaluate the effects of whole body vibration (WBV) added to conventional rehabilitation on functional and sensorimotor recovery in patients with conservatively treated distal radius fractures. Following immobilization, patients often experience pain, reduced range of motion, decreased muscle strength, and impaired proprioception, which negatively affect functional recovery. WBV is thought to enhance neuromuscular activation and improve proprioceptive input, thereby contributing to functional performance.

Participants will be randomly assigned into two groups; the experimental group will receive WBV in addition to conventional rehabilitation three times per week for eight weeks, while the control group will receive only conventional rehabilitation. Assessments will be conducted at baseline, week 4, and week 8. The primary outcome measure is the Patient-Rated Wrist Evaluation (PRWE), while secondary outcomes include QuickDASH, Numeric Pain Rating Scale (NPRS), joint position sense, grip strength, range of motion, and fine motor skills.

Read the detailed description

This study is designed as a single-center, randomized controlled clinical trial to evaluate the effects of whole body vibration (WBV) added to conventional rehabilitation on functional and sensorimotor recovery in patients with conservatively treated distal radius fractures. Distal radius fractures are among the most common upper extremity injuries and may lead to pain, reduced range of motion, decreased muscle strength, and impaired proprioception following immobilization. These impairments can delay functional recovery and negatively affect the return to daily activities.

Whole body vibration is considered a complementary rehabilitation approach that can enhance neuromuscular activation through mechanical stimulation and may improve proprioceptive input via muscle spindle activation and afferent pathways. Therefore, WBV is thought to contribute to improvements in coordination, muscle performance, and overall functional outcomes.

A total of 66 participants who meet the inclusion criteria will be randomly assigned into two groups. The experimental group will receive WBV in addition to a conventional rehabilitation program, while the control group will receive only the conventional rehabilitation program. Both groups will undergo treatment three times per week for eight weeks, with each session lasting approximately 45-60 minutes.

The WBV intervention will be applied using a vibration platform at a frequency of 30-35 Hz and a low amplitude (2 mm). The intervention protocol will be progressively increased over time, and exercises will be performed in two positions: an upper extremity weight-bearing position and a semi-squat position.

All assessments will be conducted at baseline, week 4, and week 8 by a blinded assessor. The primary outcome measure will be the Patient-Rated Wrist Evaluation (PRWE). Secondary outcome measures will include the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH), Numeric Pain Rating Scale (NPRS), joint position sense (JPS), grip strength, range of motion, and fine motor skills assessed by the Nine-Hole Peg Test.

The findings of this study are expected to provide evidence regarding the clinical effectiveness of WBV in distal radius fracture rehabilitation and contribute to the development of sensorimotor-oriented rehabilitation strategies.

Conditions: Distal Radius Fracture
Being tested: Whole-Body Vibration Therapy, Conventional Rehabilitation Exercise Program
Keywords: Distal Radius Fracture, Whole Body Vibration, Proprioception, Sensorimotor Function, Wrist Rehabilitation, Randomized Controlled Trial, Conservative Treatment
Medical subject headings: Wrist Fractures

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Whole-Body Vibration TherapyDevice
Whole-body vibration therapy will be administered using a Power Plate device at a frequency of 35 Hz and an amplitude of 2 mm, three sessions per week for 8 weeks, in addition to a standardized conventional rehabilitation program.
Conventional Rehabilitation Exercise ProgramOther
Participants will receive a standardized conventional rehabilitation program including range of motion exercises, strengthening exercises, proprioceptive training, functional activities, and patient education three times per week for 8 weeks.

Study groups in NCT07723456
Study group	Role	What they receive
Whole-Body Vibration + Conventional Rehabilitation	Experimental	Participants assigned to this arm will receive conventional rehabilitation combined with whole-body vibration therapy three times per week for 8 weeks. Receives: Device: Whole-Body Vibration Therapy; Other: Conventional Rehabilitation Exercise Program
Conventional Rehabilitation	Active comparator	Participants assigned to this arm will receive the same conventional rehabilitation program without whole-body vibration therapy for 8 weeks. Receives: Other: Conventional Rehabilitation Exercise Program

What is being measured

The primary outcome is the main question the study is designed to answer.

Patient-Rated Wrist Evaluation (PRWE) Score
The Patient-Rated Wrist Evaluation (PRWE) questionnaire will be used to assess wrist pain and function. Scores range from 0 to 100, with lower scores indicating better wrist function and less pain.
Measured: From baseline to Week 8 (assessed at baseline, Week 4, and Week 8)

Secondary outcomes (6)

Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) Score
Upper extremity disability and functional status will be assessed using the QuickDASH questionnaire. Scores range from 0 to 100, with lower scores indicating better upper extremity function.
Measured: Baseline, Week 4, and Week 8
Numeric Pain Rating Scale (NPRS)
Pain intensity will be evaluated using the Numeric Pain Rating Scale (NPRS), with scores ranging from 0 (no pain) to 10 (worst imaginable pain). Lower scores indicate less pain.
Measured: Baseline, Week 4, and Week 8
Wrist Joint Position Sense (JPS)
Wrist proprioception will be assessed using a joint position sense (JPS) test by measuring the absolute angular error between the target position and the reproduced position. Lower values indicate better proprioceptive accuracy.
Measured: Baseline, Week 4, and Week 8
Grip Strength
Grip strength will be measured using a calibrated hand dynamometer. The average of three trials will be recorded, with higher values indicating greater grip strength.
Measured: Baseline, Week 4, and Week 8
Wrist Range of Motion
Wrist and forearm range of motion will be measured using a goniometer. Higher angular values indicate greater joint mobility.
Measured: Baseline, Week 4, and Week 8
Nine-Hole Peg Test
Fine motor dexterity will be evaluated using the Nine-Hole Peg Test. The time required to complete the test will be recorded in seconds, with shorter completion times indicating better hand dexterity.
Measured: Baseline, Week 4, and Week 8

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

25 Jul 202625 May 2027

First posted23 Jul 2026
Study start25 Jul 2026 (estimated)
Primary completion25 Aug 2026 (estimated)
Study completion25 May 2027 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Distal Radius FractureStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Model description: Participants will be randomly assigned in a 1:1 ratio to either the experimental group (whole body vibration plus conventional rehabilitation) or the control group (conventional rehabilitation alone). Both groups will be followed in parallel throughout the 8-week intervention period and assessed at baseline, week 4, and week 8.
Masking: Single blind
Who is masked: Outcomes assessor
Enrolment: 66 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07723456
Sponsor's protocol ID: 4801240324
Acronym: WBV-DRF
Status last verified: Jul 2026
First submitted: 15 Jul 2026
Last updated: 23 Jul 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No

Interested in taking part?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

Official record

RecruitingPhase 1
Impact of Early ADL Education on Outcomes Post DRF ORIF
Distal Radius Fractures
Recruiting
Optimal Duration of Longitudinal Mechanical Traction in Displaced Radius Fractures: a Prospective Non-inferiority Study
Distal Radius Fracture
Recruiting
Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures
Distal Radius Fracture
Active, not recruitingPhase 4
Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial.
Distal Radius Fractures, Fracture Dislocation
Recruiting
ESWT for CRPS-I After Distal Radius Fracture
Complex Regional Pain Syndrome Type I (CRPS-I), Distal Radius Fracture

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