Bronchiectasis AdultNCT07725991
Combined Effects of Resonant Breathing and Qigong Exercises in Bronchiectasis
A study testing Resonant breathing and Qigong Exercise. and Resonant breathing exercise in people with Bronchiectasis Adult, run by Riphah International University at 1 site in Pakistan.
Trial summary
Bronchiectasis is a chronic lung disease characterized by permanent dilation of the bronchi, leading to persistent cough, mucus overproduction, dyspnea and frequent respiratory infections. Read more about this study
- Who is it for?
- Ages 40 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Bronchiectasis Adult
- What is being tested?
- Resonant breathing and Qigong Exercise. and Resonant breathing exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 46 participants
- Where
- 1 sitePakistan
- Study dates
- 20 Dec 2025to 20 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adults aged 40 to 65 years
- Both male and female participants
- Diagnosed with bronchiectasis confirmed by clinical and radiological findings
- Clinically stable for at least 4 weeks (no acute exacerbation)
- Willing and able to participate in breathing and/or Qigong exercise sessions regularly for 3 weeks
Who cannot join
- Individuals who have experienced a recent flare-up of bronchiectasis in the last month.
- Patients with serious heart, muscle, or nerve disorders that restrict movement
- Participants already enrolled in other respiratory therapy programs.
- Those with mental or communication difficulties preventing proper participation.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Combined Effects of Resonant Breathing and Qigong Exercises on Pulmonary Functions, Dyspnea and Quality of Life in Patients With Bronchiectasis
Bronchiectasis is a chronic lung disease characterized by permanent dilation of the bronchi, leading to persistent cough, mucus overproduction, dyspnea and frequent respiratory infections. It is persistent respiratory symptoms and irreversible airway dilation due to chronic inflammation and impaired mucociliary clearance, often resulting from repeated infections or underlying conditions. This conditions leads to chronic cough, sputum production and breathlessness. Pilmonary rehabilitation is recommended as a reliable strategy for respiratory management, leading to improved lung function, reduced dyspnea and enhanced quality of life. Resonant breathing and Qigong exercise are effective in enhancing respiratory function by improving oxygen intake, relaxation and respiratory muscle strength.
A randomized controlled trial will be conducted at DHQ Hospital Sheikhupura. Sample size is 46 calculated by epitool sample size calculator Convenient Sampling Technique will be used age 40 to 65 years consent will be obtained from all patients. Patients will be randomly assigned to group A and group B using simple random sampling. Group A will receive resonant breathing training with standard medical treatment. Group B will received combination of resonant breathing and Qigong exercises. Outcome measures include spirometer, MMRC dysnea scale and a quality of life questionnaire BHQ. Study will be completed within 10 months of duration treatment evaluation will be done after 3 weeks of exercise training program data will be processed using SPSS version 25. normality of data will be assessed through the Shapiro-Wilk test to determine the application of either
Read the detailed description
Interventions:
Resonant Breathing (Group A):
Resonant breathing is a calm, steady breathing technique that improves lung function and relaxes the body. Patients will sit comfortably with their feet on the ground. They will breathe in through the nose for 5 seconds, expanding their belly.Then breathe out slowly through the mouth for 5 seconds, relaxing completely.This pattern creates a steady rhythm of 5 to 6 breaths per minute.A timer or app may help guide the timing.Each breathing session will be 15 minutes long, done twice daily 5 days per week for 3 weeks.Patients will be randomly assigned to group A and group B using simple random sampling. Group A will receive resonant breathing training with standard medical treatment. The exercise protocol will include 15-minute sessions, twice daily, five days a week for 3 weeks.
Group B : Combination of Resonant and Qigong exercise They will receive a combination of resonant breathing and Qigong exercises Qigong is a gentle, ancient Chinese practice that integrates slow body movements, controlled breathing, and focused awareness. It is designed to balance the body's internal energy (Qi) and support overall wellness. The exercises are easy to perform and adaptable to various fitness levels.
Qigong helps improve respiratory efficiency, reduce anxiety, and boost immunity. It's especially beneficial for individuals managing chronic health conditions. Qigong promotes relaxation by calming the nervous system and enhancing mindfulness. It also improves posture, flexibility, and coordination. As a low-impact exercise, it carries minimal risk of injury, making it ideal for therapeutic use. along Breathing will be receive at six breaths per minute, with equal duration's of inhalation and exhalation (5 seconds each). The exercise protocol will include 15-minute sessions, twice daily, five days a week for 3 weeks. This combined technique is designed to enhance breathing efficiency, promote relaxation, improve pulmonary function, and support autonomic nervous system regulation through the c effects of both resonant breathing and Qigong movements. Exercises will involve smooth, coordinated. Preparation will be the first step of the qigong exercise for 1 to 2 minutes. Instructions will be given to the client that stand comfortably with your feet, relax your shoulders and arms, breath slowly and deeply through your nose and clear your mind and focus on calm breathing. Second step will be touch the sky foe 2 minutes. Instructions will be given to the patients that raise both arms gently above your head while inhaling, stretch lightly toward the sky, exhale and slowly lower your arms helps open lungs and stretch the spine.third step is energy punch for 2 minutes. Make soft fists and bring them to your waist, inhale deeply, exhale as you extend one fist forward like a light punch and alternate both hand s slowly.Forth step is look back for two minutes. Gently turn your head and upper body to the left , then to the right. Keep the rest of your body ready, move slowly with deep breathing.
Fifth step will be the opening the chest for 2 minutes. Inhale and slowly spread your arm outward to the sides. Exhale as you bring the back to the front. Sixth step is let go. Inhale as you lift your arms up. Exhale and wing them down and behind gently, like releasing tension.
Seventh step will be holding the ball for 3-5 minutes. Imagine your holding a big ball in front of your chest. Keep shoulders relaxed and feel warmth in your hands. Eighth steps is closing within one minutes. Rub your palms to warmth them, gently massage your face or chest and bow slightly with thanks your practice. Both groups will continue their respective interventions for 4 weeks
- Conditions
- Bronchiectasis Adult
- Being tested
- Resonant breathing and Qigong Exercise., Resonant breathing exercise
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Resonant breathing and Qigong Exercise.Other
Also called Resonant breathing training, Resonant breathing and Qigong exercise
Arm A: Resonant Breathing Only Participants in this arm received resonant breathing training alone. The intervention involved slow, paced breathing at an optimal rhythm aimed at improving respiratory efficiency, reducing dyspnea, and enhancing pulmonary function according to the study protocol.
Arm B: Resonant Breathing + Qigong Participants in this arm received a combination of resonant breathing training and Qigong exercises. Along with the same resonant breathing protocol as Arm A, additional Qigong exercises were performed to further improve respiratory function, dyspnea, physical relaxation, and quality of life in patients with bronchiectasis according to the study protocol.
Resonant breathing exerciseOther
Also called Resonant breathing training, Resonant breathing training and Qigong exercise, Resonant breathing and Qigong exercise
Arm A: Resonant Breathing Training Participants received resonant breathing training alone, involving slow and paced breathing at an individualized optimal respiratory rate to improve pulmonary function, reduce dyspnea, and enhance breathing control in patients with bronchiectasis according to the study protocol.
Arm B: Qigong with Resonant Breathing Participants received a combined intervention of resonant breathing training along with structured Qigong exercises. This group performed the same resonant breathing protocol as Arm A, with the addition of Qigong movements designed to further improve respiratory efficiency, physical relaxation, and quality of life in patients with bronchiectasis according to the study protocol.
| Study group | Role | What they receive |
|---|---|---|
| Resonant breathing exercise | Experimental | Resonant breathing training involving slow, paced breathing at an optimal breathing rate to enhance respiratory efficiency, reduce dyspnea, and improve pulmonary function according to the study protocol. Receives: Other: Resonant breathing exercise |
| Resonant breathing and Qigong exercise | Experimental | A combined intervention involving resonant breathing training performed at a slow, paced respiratory rhythm along with structured Qigong exercises aimed at improving pulmonary function, reducing dyspnea, enhancing physical relaxation, and improving quality of life in patients with bronchiectasis according to the study protocol. Receives: Other: Resonant breathing and Qigong Exercise. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in St. George's Respiratory Questionnaire (SGRQ)
_The primary outcome is the change in quality of life measured using the St. George's Respiratory Questionnaire (SGRQ). Lower scores indicate better quality of life.
Measured: Baseline of 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jul 2026
- Study start20 Dec 2025
- Primary completion25 Jan 2026
- Study completion20 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Bronchiectasis AdultStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- A parallel-group randomized trial comparing combined resonant breathing + Qigong exercises vs. standard care in bronchiectasis patients.
- Masking
- None (open label)
- Enrolment
- 46 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Tasneem Shahzadi, MS, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07725991
- Sponsor's protocol ID
- F24C14G36030
- Status last verified
- Jul 2026
- First submitted
- 21 Jul 2026
- Last updated
- 24 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Combined Effects of Resonant Breathing and Qigong Exercises on Pulmonary Functions, Dyspnea and Quality of Life in Patients With Bronchiectasis
- ClinicalTrials.gov ID
- NCT07725991
- Acronym / sponsor ID
- F24C14G36030
- Conditions
- Bronchiectasis Adult
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 46 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 20 Dec 2025 (actual)
- Primary completion
- 25 Jan 2026 (actual)
- Study completion
- 20 Jul 2026 (estimated)
- First posted
- 24 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Bronchiectasis is a chronic lung disease characterized by permanent dilation of the bronchi, leading to persistent cough, mucus overproduction, dyspnea and frequent respiratory infections. It is persistent respiratory symptoms and irreversible airway dilation due to chronic inflammation and impaired mucociliary clearance, often resulting from repeated infections or underlying conditions. This conditions leads to chronic cough, sputum production and breathlessness. Pilmonary rehabilitation is recommended as a reliable strategy for respiratory management, leading to improved lung function, reduced dyspnea and enhanced quality of life. Resonant breathing and Qigong exercise are effective in enhancing respiratory function by improving oxygen intake, relaxation and respiratory muscle strength.
A randomized controlled trial will be conducted at DHQ Hospital Sheikhupura. Sample size is 46 calculated by epitool sample size calculator Convenient Sampling Technique will be used age 40 to 65 years consent will be obtained from all patients. Patients will be randomly assigned to group A and group B using simple random sampling. Group A will receive resonant breathing training with standard medical treatment. Group B will received combination of resonant breathing and Qigong exercises. Outcome measures include spirometer, MMRC dysnea scale and a quality of life questionnaire BHQ. Study will be completed within 10 months of duration treatment evaluation will be done after 3 weeks of exercise training program data will be processed using SPSS version 25. normality of data will be assessed through the Shapiro-Wilk test to determine the application of either
Detailed description
Interventions:
Resonant Breathing (Group A):
Resonant breathing is a calm, steady breathing technique that improves lung function and relaxes the body. Patients will sit comfortably with their feet on the ground. They will breathe in through the nose for 5 seconds, expanding their belly.Then breathe out slowly through the mouth for 5 seconds, relaxing completely.This pattern creates a steady rhythm of 5 to 6 breaths per minute.A timer or app may help guide the timing.Each breathing session will be 15 minutes long, done twice daily 5 days per week for 3 weeks.Patients will be randomly assigned to group A and group B using simple random sampling. Group A will receive resonant breathing training with standard medical treatment. The exercise protocol will include 15-minute sessions, twice daily, five days a week for 3 weeks.
Group B : Combination of Resonant and Qigong exercise They will receive a combination of resonant breathing and Qigong exercises Qigong is a gentle, ancient Chinese practice that integrates slow body movements, controlled breathing, and focused awareness. It is designed to balance the body's internal energy (Qi) and support overall wellness. The exercises are easy to perform and adaptable to various fitness levels.
Qigong helps improve respiratory efficiency, reduce anxiety, and boost immunity. It's especially beneficial for individuals managing chronic health conditions. Qigong promotes relaxation by calming the nervous system and enhancing mindfulness. It also improves posture, flexibility, and coordination. As a low-impact exercise, it carries minimal risk of injury, making it ideal for therapeutic use. along Breathing will be receive at six breaths per minute, with equal duration's of inhalation and exhalation (5 seconds each). The exercise protocol will include 15-minute sessions, twice daily, five days a week for 3 weeks. This combined technique is designed to enhance breathing efficiency, promote relaxation, improve pulmonary function, and support autonomic nervous system regulation through the c effects of both resonant breathing and Qigong movements. Exercises will involve smooth, coordinated. Preparation will be the first step of the qigong exercise for 1 to 2 minutes. Instructions will be given to the client that stand comfortably with your feet, relax your shoulders and arms, breath slowly and deeply through your nose and clear your mind and focus on calm breathing. Second step will be touch the sky foe 2 minutes. Instructions will be given to the patients that raise both arms gently above your head while inhaling, stretch lightly toward the sky, exhale and slowly lower your arms helps open lungs and stretch the spine.third step is energy punch for 2 minutes. Make soft fists and bring them to your waist, inhale deeply, exhale as you extend one fist forward like a light punch and alternate both hand s slowly.Forth step is look back for two minutes. Gently turn your head and upper body to the left , then to the right. Keep the rest of your body ready, move slowly with deep breathing.
Fifth step will be the opening the chest for 2 minutes. Inhale and slowly spread your arm outward to the sides. Exhale as you bring the back to the front. Sixth step is let go. Inhale as you lift your arms up. Exhale and wing them down and behind gently, like releasing tension.
Seventh step will be holding the ball for 3-5 minutes. Imagine your holding a big ball in front of your chest. Keep shoulders relaxed and feel warmth in your hands. Eighth steps is closing within one minutes. Rub your palms to warmth them, gently massage your face or chest and bow slightly with thanks your practice. Both groups will continue their respective interventions for 4 weeks
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- A parallel-group randomized trial comparing combined resonant breathing + Qigong exercises vs. standard care in bronchiectasis patients.
| Arm | Type | Receives |
|---|---|---|
| Resonant breathing exercise | Experimental | Other: Resonant breathing exerciseResonant breathing training involving slow, paced breathing at an optimal breathing rate to enhance respiratory efficiency, reduce dyspnea, and improve pulmonary function according to the study protocol. |
| Resonant breathing and Qigong exercise | Experimental | Other: Resonant breathing and Qigong Exercise.A combined intervention involving resonant breathing training performed at a slow, paced respiratory rhythm along with structured Qigong exercises aimed at improving pulmonary function, reducing dyspnea, enhancing physical relaxation, and improving quality of life in patients with bronchiectasis according to the study protocol. |
Who may qualify
- Ages
- 40 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Adults aged 40 to 65 years
- Both male and female participants
- Diagnosed with bronchiectasis confirmed by clinical and radiological findings
- Clinically stable for at least 4 weeks (no acute exacerbation)
- Willing and able to participate in breathing and/or Qigong exercise sessions regularly for 3 weeks
Key exclusion criteria (4 listed)
- Individuals who have experienced a recent flare-up of bronchiectasis in the last month.
- Patients with serious heart, muscle, or nerve disorders that restrict movement
- Participants already enrolled in other respiratory therapy programs.
- Those with mental or communication difficulties preventing proper participation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Resonant breathing and Qigong Exercise.Also: Resonant breathing training, Resonant breathing and Qigong exerciseArm A: Resonant Breathing Only Participants in this arm received resonant breathing training alone. The intervention involved slow, paced breathing at an optimal rhythm aimed at improving respiratory efficiency, reducing dyspnea, and enhancing pulmonary function according to the study protocol. Arm B: Resonant Breathing + Qigong Participants in this arm received a combination of resonant breathing training and Qigong exercises. Along with the same resonant breathing protocol as Arm A, additional Qigong exercises were performed to further improve respiratory function, dyspnea, physical relaxation, and quality of life in patients with bronchiectasis according to the study protocol. | Other | Resonant breathing and Qigong exercise |
| Resonant breathing exerciseAlso: Resonant breathing training, Resonant breathing training and Qigong exercise, Resonant breathing and Qigong exerciseArm A: Resonant Breathing Training Participants received resonant breathing training alone, involving slow and paced breathing at an individualized optimal respiratory rate to improve pulmonary function, reduce dyspnea, and enhance breathing control in patients with bronchiectasis according to the study protocol. Arm B: Qigong with Resonant Breathing Participants received a combined intervention of resonant breathing training along with structured Qigong exercises. This group performed the same resonant breathing protocol as Arm A, with the addition of Qigong movements designed to further improve respiratory efficiency, physical relaxation, and quality of life in patients with bronchiectasis according to the study protocol. | Other | Resonant breathing exercise |
Primary outcome
Change in St. George's Respiratory Questionnaire (SGRQ)
Time frame: Baseline of 4 weeks
_The primary outcome is the change in quality of life measured using the St. George's Respiratory Questionnaire (SGRQ). Lower scores indicate better quality of life.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jul 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Tasneem Shahzadi, MS principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Resonant breathing and Qigong Exercise. and Resonant breathing exercise in people with Bronchiectasis Adult, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 24 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in St. George's Respiratory Questionnaire (SGRQ) (time frame: Baseline of 4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jul 2026.