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Chronic Low Back Pain (CLBP)NCT07730463

Effectiveness of ELDOA Stretching Combined With Standard Physiotherapy in Adults With Chronic Low Back Pain and Dural Hypomobility; A Randomized Controlled Trial.

A study testing ELDOA Stretching and Standard Physiotherapy in people with Chronic Low Back Pain (CLBP), run by Ibadat International University, Islamabad at 1 site in Pakistan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Adults with chronic low back pain (CLBP) frequently experience persistent pain, functional disability, and reduced quality of life despite receiving conventional physiotherapy. Dural hypomobility has been proposed as a contributing factor in some individuals with CLBP by limiting normal neural tissue mobility and… Read more about this study

Who is it for?
Ages 20 to 45 years
Conditions the study is for
Chronic Low Back Pain (CLBP)
What is being tested?
ELDOA Stretching and Standard Physiotherapy
Type of treatment
Surgery or procedure
Could I receive a placebo?
No, everyone receives an active treatment
How many people
48 participants
Where
1 sitePakistan
Study dates
10 Jan 2026to 7 Jun 2026
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 45 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • Adults aged 20 to 45 years. Male or female participants. Chronic low back pain persisting for at least 3 months. Positive Slump Test indicating dural hypomobility. Localized mechanical low back pain. Able and willing to participate in the intervention program. Willing to provide written informed consent.

Who cannot join

  • History of spinal surgery within the previous 12 months. Vertebral fracture, spinal tumor, spinal infection, or other serious spinal pathology.
  • Spondylolisthesis, ankylosing spondylitis, scoliosis, or kyphosis confirmed clinically or radiographically.
  • Pregnancy. Neurological deficits or progressive neurological disorders. Skin infection or open wounds in the lumbar region that contraindicate treatment.
  • Severe systemic disease that may interfere with participation. Current participation in another clinical trial or structured physiotherapy program for low back pain.

Trial locations and contacts

1 site in 1 country.

Pakistan1 site
  • Ibadat International hospital Liaqat Rd, opposite Gordon college, Liaquat Bagh, Rawalpindi.

    Islamabad, Federal, 44000

Other trials in Pakistan

About this study

Official title: Effectiveness of ELDOA Stretching Combined With Standard Physiotherapy in Adults With Chronic Low Back Pain and Dural Hypomobility:

Adults with chronic low back pain (CLBP) frequently experience persistent pain, functional disability, and reduced quality of life despite receiving conventional physiotherapy. Dural hypomobility has been proposed as a contributing factor in some individuals with CLBP by limiting normal neural tissue mobility and increasing mechanosensitivity. ELDOA (Étirements Longitudinaux avec Décoaptation Ostéo-Articulaire) is a targeted stretching technique designed to improve spinal decompression, fascial mobility, and neural tissue mobility. However, evidence regarding its effectiveness in patients with CLBP and dural hypomobility remains limited.

This randomized controlled trial aims to evaluate the effectiveness of ELDOA stretching combined with standard physiotherapy compared with standard physiotherapy alone in adults with chronic low back pain and dural hypomobility. Participants will receive treatment three times per week for six weeks. Pain intensity, disability, and dural mobility will be assessed using the Numeric Pain Rating Scale (NPRS), Oswestry Disability Index (ODI), and Slump Test before and after the intervention. The findings may provide evidence regarding the additional benefit of ELDOA as an adjunct to conventional physiotherapy in the management of chronic low back pain associated with dural hypomobility.

Read the detailed description

Chronic low back pain (CLBP) is one of the leading causes of disability worldwide and is associated with persistent pain, reduced functional capacity, impaired quality of life, and substantial socioeconomic burden. Current clinical practice guidelines recommend non-pharmacological management, particularly exercise therapy and physiotherapy, as first-line treatment. Nevertheless, many individuals continue to experience pain and disability despite conventional rehabilitation.

Dural hypomobility has been suggested as a potential contributor to persistent low back pain. Restricted movement of the spinal dura mater may increase neural mechanosensitivity, alter neurodynamics, and contribute to pain during movement. The Slump Test is commonly used clinically to identify signs consistent with altered neural mobility or dural tension.

ELDOA (Étirements Longitudinaux avec Décoaptation Ostéo-Articulaire) is a specific therapeutic exercise technique developed to create targeted spinal decompression through fascial tensioning and segmental positioning. The technique aims to improve spinal alignment, fascial mobility, and neural tissue mobility while reducing mechanical stress on spinal structures. Although previous studies have demonstrated beneficial effects of ELDOA on pain and function in several musculoskeletal conditions, evidence regarding its effectiveness in adults with chronic low back pain accompanied by dural hypomobility is limited.

This study is designed as a single-blind randomized controlled trial. Eligible adults aged 20 to 45 years with chronic low back pain lasting at least three months and presenting with a positive Slump Test will be recruited. Participants will be randomly allocated into two groups. The experimental group will receive standard physiotherapy consisting of hot pack application, transcutaneous electrical nerve stimulation (TENS), manual therapy, and ELDOA stretching exercises. The control group will receive the same standard physiotherapy protocol without ELDOA. Both groups will receive treatment three times per week for six weeks.

The primary outcome will be pain intensity measured using the Numeric Pain Rating Scale (NPRS). Secondary outcomes will include disability measured by the Oswestry Disability Index (ODI) and dural mobility assessed using the Slump Test. Outcome measures will be recorded at baseline and after completion of the six-week intervention.

The study aims to determine whether adding ELDOA stretching to standard physiotherapy provides greater improvements in pain, disability, and dural mobility than standard physiotherapy alone. The results may contribute to evidence-based rehabilitation strategies for adults with chronic low back pain associated with dural hypomobility and help guide future physiotherapy practice.

Being tested
ELDOA Stretching, Standard Physiotherapy
Keywords
Low Back Pain, ELDOA, Dural Hypomobility
Medical subject headings
Low Back Pain

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • ELDOA StretchingProcedure or surgery

    Also called Dural Stretching

    Participants will perform standardized ELDOA (Étirements Longitudinaux avec Décoaptation Ostéo-Articulaire) stretching exercises targeting the lumbar spine (L1-L2, L2-L3, L3-L4, L4-L5, and L5-S1). Each exercise will be performed for 2 sets of 5 repetitions with a 45-second hold and 15-second rest between sets. Treatment will be supervised by a physiotherapist and administered three times per week for six weeks in addition to standard physiotherapy.

  • Standard PhysiotherapyProcedure or surgery

    Standard physiotherapy will consist of superficial heat therapy (hot pack for 10-15 minutes), transcutaneous electrical nerve stimulation (TENS, 80-100 Hz for 10-15 minutes), and manual therapy including myofascial release and soft tissue mobilization of the lumbar paraspinal muscles (5-10 minutes). Treatment will be provided three times per week for six weeks.

Study groups in NCT07730463
Study groupRoleWhat they receive
Standard Physiotherapy + ELDOA StretchingExperimentalParticipants assigned to this arm will receive standard physiotherapy consisting of hot pack application, transcutaneous electrical nerve stimulation (TENS), and manual therapy, together with ELDOA stretching exercises. Treatment will be provided three sessions per week for six weeks.
Receives: Procedure: ELDOA Stretching; Procedure: Standard Physiotherapy
Standard PhysiotherapyActive comparatorParticipants assigned to this arm will receive standard physiotherapy consisting of hot pack application, transcutaneous electrical nerve stimulation (TENS), and manual therapy. Treatment will be provided three sessions per week for six weeks.
Receives: Procedure: Standard Physiotherapy

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Disability Measured by the Oswestry Disability Index (ODI)

    Disability related to chronic low back pain will be assessed using the Oswestry Disability Index (ODI). Scores range from 0% to 100%, with higher scores indicating greater disability. The outcome is the change in ODI score from baseline to Week 6.

    Measured: Baseline and Week 6

  2. Pain Intensity Measured by the Numeric Pain Rating Scale (NPRS)

    Pain intensity will be assessed using the 11-point Numeric Pain Rating Scale (NPRS), where 0 indicates no pain and 10 indicates the worst imaginable pain. The primary outcome is the change in NPRS score from baseline to the end of the 6-week intervention.

    Measured: Baseline and Week 6

Secondary outcomes (1)
  1. Dural Mobility Assessed by the Slump Test

    Dural mobility will be evaluated using the Slump Test. Improvement will be determined by changes in symptom reproduction and neural mobility findings between baseline and the end of the intervention.

    Measured: Baseline and Week 6

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted28 Jul 2026
  2. Study start10 Jan 2026
  3. Primary completion30 May 2026
  4. Study completion7 Jun 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Model description
This is a two-arm, parallel-group, randomized controlled trial. Eligible participants with chronic low back pain and dural hypomobility will be randomly allocated in a 1:1 ratio to either the experimental group (standard physiotherapy plus ELDOA stretching) or the control group (standard physiotherapy alone). Both groups will receive treatment three times per week for six weeks. Outcomes will be assessed at baseline and at the end of the intervention period.
Masking
Single blind
Who is masked
Participant
Enrolment
48 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07730463
Sponsor's protocol ID
IIUI/RERC/ADT/2026/02/235
Status last verified
Jul 2026
First submitted
23 Jul 2026
Last updated
28 Jul 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: Individual participant data (IPD) collected during this study will not be made publicly available because participant confidentiality and privacy will be protected in accordance with institutional ethical guidelines and informed consent procedures. Only aggregated study results will be reported in publications and presentations.

Publications

  • 1. Aboagye, E., Karlsson, M., Hagberg, J., & Jensen, I. (2015). Cost-effectiveness of early interventions for non-specific low back pain: A randomized controlled study investigating medical yoga, exercise therapy and self-care advice. Journal of Rehabilitation Medicine, 47(2), 167-173. https://doi.org/10.2340/16501977-1910 2. Adams, M. A., & Hutton, W. C. (1982). The mechanics of prolapsed intervertebral disc. International Orthopaedics, 6(4), 249-253. https://doi.org/10.1007/BF00267146 3. Baldassarre, M. E., Di Mauro, A., Pignatelli, M. C., Fanelli, M., Salvatore, S., Di Nardo, G., Chiaro, A., Pensabene, L., & Laforgia, N. (2019). Magnesium alginate in gastro-esophageal reflux: A randomized multicenter cross-over study in infants. International Journal of Environmental Research and Public Health, 17(1), 83. https://doi.org/10.3390/ijerph17010083 4. Childs, J. D., Piva, S. R., & Fritz, J. M. (2005). Responsiveness of the numeric pain rating scale in patients with low back pain. Spine, 30(11), 1331-1334. https://doi.org/10.1097/01.brs.0000164099.92112.29 5. Chou, R., Deyo, R., Friedly, J., Skelly, A., Hashimoto, R., Weimer, M., Fu, R., Dana, T., Kraegel, P., Griffin, J., Grusing, S., & Brodt, E. D. (2017). Nonpharmacologic therapies for low back pain: A systematic review for an American College of Physicians clinical practice guideline. Annals of Internal Medicine, 166(7), 493-505. https://doi.org/10.7326/m16-2459 6. Coppieters, M. W., & Butler, D. S. (2007). Do 'sliders' slide and 'tensioners' tension? An analysis of neurodynamic techniques and considerations regarding their application. Manual Therapy, 13(3), 213-221. https://doi.org/10.1016/j.math.2006.12.008 7. Fairbank, J. C. T., & Pynsent, P. B. (2000). The Oswestry Disability Index. Spine, 25(22), 2940-2953. https://doi.org/10.1097/00007632-200011150-00017 8. Farooq, M., Bashir, M. S., Arif, A., Kashif, M., Manzoor, N., & Abid, F. (2023). Effects of elongation longitudinaux avec decoaption osteo-articulaire

Questions about this trial

What is this clinical trial studying?

A study testing ELDOA Stretching and Standard Physiotherapy in people with Chronic Low Back Pain (CLBP), run by Ibadat International University, Islamabad at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 28 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Disability Measured by the Oswestry Disability Index (ODI) (time frame: Baseline and Week 6). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07730463, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Jul 2026.

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