Tooth LossNCT07737197
Single _ Drill Vs Full Sequence Guided Implant Placement
A study testing Full-sequence computer-guided dental implant placement. and Single-drill computer-guided dental implant placement in people with Tooth Loss and Partial Edentulism, run by Cairo University at 1 site in Egypt.
Trial summary
This randomized clinical trial aims to compare the accuracy of single-drill (pilot-guided) computer-guided implant surgery versus full-sequence computer-guided dental implant placement. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Tooth Loss, Partial Edentulism
- What is being tested?
- Full-sequence computer-guided dental implant placement. and Single-drill computer-guided dental implant placement
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 16 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Sep 2025to 10 Jul 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age >= 18 years, both sexes
- Patients requiring dental implant placement in the posterior region (molar area)
- Patients systemically healthy with no medical history contraindicating implant surgery
- Sufficient inter-arch space for future prosthesis (minimum 7 mm)
Who cannot join
- Bone height < 6 mm at the proposed implant site
- Inadequate oral hygiene
- Heavy smoking (>10 cigarettes/day)
- Alcohol or drug abuse
- Pregnancy
- Local or systemic infection
Show all 13Show fewer
- Uncontrolled metabolic disease (e.g., diabetes mellitus)
- Severe hepatic or renal dysfunction
- Chemotherapy or radiotherapy within the last 5 years
- Immunosuppression therapy or autoimmune disorders
- Complete edentulism
- Pathological conditions such as periapical or periodontal abscesses
- Untreated gingivitis or periodontitis
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Accuracy of Single Drill Versus Full Sequence Computer Guidance in Dental Implant Placement
This randomized clinical trial aims to compare the accuracy of single-drill (pilot-guided) computer-guided implant surgery versus full-sequence computer-guided dental implant placement. The study evaluates clinical and radiographic outcomes, focusing on apical, angular, coronal, and depth linear deviations using post-operative cone-beam computed tomography (CBCT) superimposition.
- Conditions
- Tooth Loss, Partial Edentulism
- Being tested
- Full-sequence computer-guided dental implant placement., Single-drill computer-guided dental implant placement
- Keywords
- implant, Dental Implants, Computer-Guided Surgery, Pilot-Guided Surgery
- Medical subject headings
- Tooth Loss
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Full-sequence computer-guided dental implant placement.Procedure or surgery
Dental implant placement using full sequence computer guidance with all sequential drills and metal reducers
Single-drill computer-guided dental implant placementProcedure or surgery
Dental implant placement using first-drill (pilot-guided) computer guidance, followed by freehand sequential drilling and placement
| Study group | Role | What they receive |
|---|---|---|
| Full Sequence Computer Guidance | Experimental | Patients undergo dental implant placement using full-sequence computer guidance, where implant site preparation and insertion are accomplished using all sequential drills and metal reducers with the surgical guide. Receives: Procedure: Full-sequence computer-guided dental implant placement. |
| Single Drill / Pilot-Guided Computer Guidance | Active comparator | Patients undergo dental implant placement using first-drill (pilot-guided) computer guidance, where the initial pilot osteotomy is performed through the surgical guide, followed by removal of the guide and completion of the remaining sequential drilling and implant placement freehand. Receives: Procedure: Single-drill computer-guided dental implant placement |
What is being measured
The primary outcome is the main question the study is designed to answer.
Apical deviation
The linear deviation between the planned and actual implant apex position measured on post-operative CBCT superimposition.
Measured: Immediately after surgery (Post-operative CBCT).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Jul 2026
- Study start10 Sep 2025
- Primary completion10 Jul 2026
- Study completion10 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tooth LossStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 16 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Alnoor Ahmed Mohammed, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07737197
- Sponsor's protocol ID
- Guided-Implant-RCT-2026
- Status last verified
- Jul 2026
- First submitted
- 27 Jul 2026
- Last updated
- 31 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Accuracy of Single Drill Versus Full Sequence Computer Guidance in Dental Implant Placement
- ClinicalTrials.gov ID
- NCT07737197
- Acronym / sponsor ID
- Guided-Implant-RCT-2026
- Conditions
- Tooth Loss, Partial Edentulism
- Keywords
- implant, Dental Implants, Computer-Guided Surgery, Pilot-Guided Surgery
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 16 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 10 Sep 2025 (actual)
- Primary completion
- 10 Jul 2026 (actual)
- Study completion
- 10 Jul 2026 (actual)
- First posted
- 30 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized clinical trial aims to compare the accuracy of single-drill (pilot-guided) computer-guided implant surgery versus full-sequence computer-guided dental implant placement. The study evaluates clinical and radiographic outcomes, focusing on apical, angular, coronal, and depth linear deviations using post-operative cone-beam computed tomography (CBCT) superimposition.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Full Sequence Computer Guidance | Experimental | Procedure: Full-sequence computer-guided dental implant placement.Patients undergo dental implant placement using full-sequence computer guidance, where implant site preparation and insertion are accomplished using all sequential drills and metal reducers with the surgical guide. |
| Single Drill / Pilot-Guided Computer Guidance | Active comparator | Procedure: Single-drill computer-guided dental implant placementPatients undergo dental implant placement using first-drill (pilot-guided) computer guidance, where the initial pilot osteotomy is performed through the surgical guide, followed by removal of the guide and completion of the remaining sequential drilling and implant placement freehand. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Age >= 18 years, both sexes
- Patients requiring dental implant placement in the posterior region (molar area)
- Patients systemically healthy with no medical history contraindicating implant surgery
- Sufficient inter-arch space for future prosthesis (minimum 7 mm)
Key exclusion criteria (13 listed)
- Bone height < 6 mm at the proposed implant site
- Inadequate oral hygiene
- Heavy smoking (>10 cigarettes/day)
- Alcohol or drug abuse
- Pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Full-sequence computer-guided dental implant placement.Dental implant placement using full sequence computer guidance with all sequential drills and metal reducers | Procedure or surgery | Full Sequence Computer Guidance |
| Single-drill computer-guided dental implant placementDental implant placement using first-drill (pilot-guided) computer guidance, followed by freehand sequential drilling and placement | Procedure or surgery | Single Drill / Pilot-Guided Computer Guidance |
Primary outcome
Apical deviation
Time frame: Immediately after surgery (Post-operative CBCT).
The linear deviation between the planned and actual implant apex position measured on post-operative CBCT superimposition.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Jul 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Full-sequence computer-guided dental implant placement. and Single-drill computer-guided dental implant placement in people with Tooth Loss and Partial Edentulism, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 31 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Apical deviation (time frame: Immediately after surgery (Post-operative CBCT).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Jul 2026.