AzTrials
AzTrials

HealthyNCT07739238

THE EFFECTS OF DIFFERENT BREATHING EXERCISES ON RESPIRATORY PARAMETERS AND HEART RATE VARIABILITY

A study testing breathing exercises in people with Healthy, run by Bandırma Onyedi Eylül University at 1 site in Turkey (Türkiye).

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
Search all trials

Trial summary

Breathing is a vital process that occurs automatically, but it can also be voluntarily controlled to achieve specific goals, especially preventive and therapeutic ones. Slow breathing has been reported to have many physical and mental health benefits. Read more about this study

Who is it for?
Ages 18 to 30 yearsHealthy volunteers can take part
Conditions the study is for
Healthy
What is being tested?
breathing exercises
Could I receive a placebo?
No, everyone receives an active treatment
How many people
44 participants
Where
1 siteTurkey (Türkiye)
Study dates
1 Feb 2024to Sep 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 30 years
  • All sexes
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • Individuals willing to participate in the study
  • Individuals aged between 18 and 30 years
  • Individuals without a history of regular sports or physical activity habits

Who cannot join

  • Immobilized individuals
  • Athletes
  • Individuals with respiratory, cardiovascular, or renal system diseases
  • Individuals using medication for respiratory, cardiovascular, or renal system problems
  • Individuals who have undergone any surgery in the last 6 months
  • Individuals with neurological, systemic, or musculoskeletal disorders

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Turkey (Türkiye)1 site, 1 recruiting
  • Bandirma Onyedi Eylül University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

    Balıkesir, In the USA Or Canada, Please Select..., 10250

    ESRA KESKİN, DR, +902667170117 ext. 4550, ekeskin@bandirma.edu.tr

    Recruiting

Other trials in Turkey (Türkiye)

About this study

Breathing is a vital process that occurs automatically, but it can also be voluntarily controlled to achieve specific goals, especially preventive and therapeutic ones. Slow breathing has been reported to have many physical and mental health benefits. The activation of the sympathetic system during inhalation and the increase in heart rate, as well as the activation of the parasympathetic system during exhalation and the resulting decrease in heart rate variability, can be affected by breathing exercises. The physiological effects associated with breathing exercises vary depending on the type of exercise performed. Therefore, investigating and comparing the clinical effects and contributions of different breathing exercises will shed light on which breathing exercises should be preferred in different situations.

This study aims to examine the effects of diaphragmatic breathing, square breathing technique, alternative nostril breathing exercises, and diaphragmatic breathing exercises on respiratory function parameters and heart rate variability, and to compare these different breathing exercises. Healthy individuals aged 18-30 years from the Department of Physiotherapy and Rehabilitation at Bandırma Onyedi Eylül University will be invited to participate in the study. For the study, a sample size of 40 was determined in the "G*Power" analysis system with a moderate effect size according to Cohen, a statistical significance threshold of 5% (alpha level = 0.05), and 80% power (Cohen, J.; 2013), allowing for evaluation of the four groups before the training program, immediately after the first session (acute effect), and after the training program (6 weeks). To account for potential dropouts, the target is to reach 44 participants, which is 10% more than the calculated sample size. Power calculations will be performed during the study process, and revisions regarding sample size will be made if necessary. Participants will be randomized using a sealed envelope randomization method. Respiratory function tests (FVC-FEV1- FEV1/FVC- FEF- PEF) will be performed using a COSMED Pony FX portable spirometer to evaluate participants' respiratory functions. Heart rate variability will be assessed by taking a 5-minute measurement using a Polar H10 device. Four different breathing exercise groups will be created, and participants will undergo diaphragmatic breathing exercises, square breathing technique exercises, alternative nostril breathing exercises, and dynamic neuromuscular stabilization-based breathing exercises for 6 weeks, with sessions lasting 20 minutes, four times a week. The initial session will be conducted face-to-face, while subsequent sessions will be conducted online (via zoom/video calls/Google Meet, etc.). Assessments will be conducted three times: at baseline, immediately after the first session (acute effect), and after the 6-week training program, and will be performed face-to-face.

Conditions
Healthy
Being tested
breathing exercises

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • breathing exercisesOther

    diaphragmatic breathing exercises, square breathing technique exercises, alternative nostril breathing exercises, and dynamic neuromuscular stabilization-based breathing exercises

Study groups in NCT07739238
Study groupRoleWhat they receive
diaphragmatic breathing exercisesExperimentaldiaphragmatic breathing exercises
Receives: Other: breathing exercises
square breathing technique exercisesExperimentalNot described
Receives: Other: breathing exercises
alternative nostril breathing exercisesExperimentalNot described
Receives: Other: breathing exercises
dynamic neuromuscular stabilization-based breathing exercisesExperimentalNot described
Receives: Other: breathing exercises

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Heart Rate Variability

    Heart Rate Variability

    Measured: day 1/ acute (after the first session-in an hour)/six week

  2. respiratory parameters

    FEV

    Measured: day 1/ acute (after the first session-in an hour)/six week

  3. respiratory parameters

    FEV1

    Measured: day 1/ acute (after the first session-in an hour)/six week

  4. respiratory parameters

    FVC

    Measured: day 1/ acute (after the first session-in an hour)/six week

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted31 Jul 2026
  2. Study start1 Feb 2024
  3. Primary completionAug 2026 (estimated)
  4. Study completionSep 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Prevention
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Participant
Enrolment
44 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07739238
Sponsor's protocol ID
2023-270
Status last verified
Oct 2025
First submitted
31 Mar 2024
Last updated
31 Jul 2026
Results posted
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided

Questions about this trial

What is this clinical trial studying?

A study testing breathing exercises in people with Healthy, run by Bandırma Onyedi Eylül University at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 31 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Heart Rate Variability (time frame: day 1/ acute (after the first session-in an hour)/six week). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Jul 2026.

Free account

Log in to keep searching

You’ve used your 3 free searches. AzTrials is free: log in or create a free account to keep searching clinical trials and save the ones you want to follow.

Create a free accountLog in