Mucus ClearanceNCT07740746
A Study to Evaluate the Effects of a Supplement on Mucus Clearance and Respiratory Symptoms
A study testing BetterLungs in people with Mucus Clearance and Respiratory Symptoms, run by The Better Brand Inc. at 1 site in United States.
Trial summary
This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of the BetterLungs Mullein + Chlorophyll supplement on mucus clearance and respiratory symptoms over 60 days. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Mucus Clearance, Respiratory Symptoms, Breathlessness
- What is being tested?
- BetterLungs
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 100 participants
- Where
- 1 siteUnited States
- Study dates
- 22 Apr 2025to 30 Aug 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Be male or female
- Be aged 18+
- Anyone experiencing issues regarding all of the following over the past three months: a build-up of chest mucus, difficulty clearing chest mucus, breathlessness, and low energy levels
- Anyone who is generally healthy - does not live with any uncontrolled chronic disease
- Willing to refrain from taking any products, prescription medications, or supplements that target lung health, mucus, and energy levels during the test period
- Willing to maintain your current diet, sleep schedule, and activity level for the duration of the study
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- Resides in the United States
- Not currently partaking in another research study and will not be partaking in any other research study for the next 60 days and at any point during this study's duration
- If currently taking prescription medication are willing to discuss it with their physician before participating in this study
Who cannot join
- Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including kidney disease, diabetes, cancer, mental health disorders, history of serious illness in the last three months, history of substance abuse, or planned surgery during the study period
- Anyone who drinks heavily (i.e. 8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men)
- Anyone with a copper sensitivity disorder (such as Wilson's disease or copper metabolism disorders)
- Anyone with kidney disease
- Anyone with diabetes
- Anyone with any known allergies or hypersensitivities to any supplement product ingredients
- Anyone who is currently pregnant, trying to conceive, or breastfeeding
Trial locations and contacts
1 site in 1 country.
About this study
This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of the BetterLungs Mullein + Chlorophyll supplement on mucus clearance and respiratory symptoms over 60 days. One hundred adult participants experiencing chest mucus build-up, difficulty clearing mucus, breathlessness, and low energy levels will be enrolled and randomized to either the active supplement or a matched placebo.
Participants will take their assigned product once daily in the morning mixed with water and will complete self-reported questionnaires at Baseline, Day 20, Day 40, and Day 60.
- Conditions
- Mucus Clearance, Respiratory Symptoms, Breathlessness, Chest Mucus Accumulation, Low Energy Levels
- Being tested
- BetterLungs, Placebo
- Medical subject headings
- Signs and Symptoms, Respiratory, Dyspnea
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
BetterLungsDietary supplement
50 participants receive the BetterLungs Mullein + Chlorophyll supplement (ingredients: mullein leaf, chlorophyll, vegetable glycerin, purified water) taken once daily in the morning with the first meal of the day; 2 mL (two full droppers) mixed with 8 ounces of water for 60 days
PlaceboDietary supplement
50 participants receive a matched placebo product (ingredients: moss coloring jungle green color, violet color, spirulina, vegetable glycerin, purified water) taken once daily in the morning with the first meal of the day; 2 mL (two full droppers) mixed with 8 ounces of water for 60 days; the taste and appearance of the placebo are matched to the active product
| Study group | Role | What they receive |
|---|---|---|
| BetterLungs Mullein | Experimental | Not described Receives: Dietary Supplement: BetterLungs |
| Placebo | Placebo comparator | Not described Receives: Dietary Supplement: Placebo |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in mucus clearance
Self-reported change in mucus clearance assessed via questionnaire
Measured: Baseline, Day 20, Day 40, and Day 60
Change in respiratory symptoms
Self-reported change in respiratory symptoms assessed via questionnaire
Measured: Baseline, Day 20, Day 40, and Day 60
Secondary outcomes (6)
Change in perceived mucus clearance
Participant-perceived change in mucus clearance assessed via self-reported questionnaire
Measured: Baseline, Day 20, Day 40, and Day 60
Change in energy levels
Participant-perceived change in energy levels assessed via self-reported questionnaire
Measured: Baseline, Day 20, Day 40, and Day 60
Change in shortness of breath
Participant-perceived change in shortness of breath associated with physical activity assessed via self-reported questionnaire
Measured: Baseline, Day 20, Day 40, and Day 60
Change in breathing-related anxiety
Participant-perceived change in breathing-related anxiety assessed via self-reported questionnaire
Measured: Baseline, Day 20, Day 40, and Day 60
Change in ease of breathing
Participant-perceived change in ease of breathing assessed via self-reported questionnaire
Measured: Baseline, Day 20, Day 40, and Day 60
Change in general well-being
Participant-perceived change in general well-being assessed via self-reported questionnaire
Measured: Baseline, Day 20, Day 40, and Day 60
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Aug 2026
- Study start22 Apr 2025
- Primary completion30 Aug 2025
- Study completion30 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Mucus ClearanceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 100 participants (actual)
Sponsor and investigators
- Lead sponsor
- The Better Brand Inc.
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07740746
- Sponsor's protocol ID
- 20752
- Status last verified
- Jul 2026
- First submitted
- 28 Jul 2026
- Last updated
- 3 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Study to Evaluate the Effects of a Supplement on Mucus Clearance and Respiratory Symptoms
- ClinicalTrials.gov ID
- NCT07740746
- Acronym / sponsor ID
- 20752
- Conditions
- Mucus Clearance, Respiratory Symptoms, Breathlessness, Chest Mucus Accumulation, Low Energy Levels
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 100 participants (actual)
- Lead sponsor
- The Better Brand Inc.Industry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Study start
- 22 Apr 2025 (actual)
- Primary completion
- 30 Aug 2025 (actual)
- Study completion
- 30 Aug 2025 (actual)
- First posted
- 3 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of the BetterLungs Mullein + Chlorophyll supplement on mucus clearance and respiratory symptoms over 60 days. One hundred adult participants experiencing chest mucus build-up, difficulty clearing mucus, breathlessness, and low energy levels will be enrolled and randomized to either the active supplement or a matched placebo.
Participants will take their assigned product once daily in the morning mixed with water and will complete self-reported questionnaires at Baseline, Day 20, Day 40, and Day 60.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| BetterLungs Mullein | Experimental | Dietary Supplement: BetterLungs |
| Placebo | Placebo comparator | Dietary Supplement: Placebo |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (9 listed)
- Be male or female
- Be aged 18+
- Anyone experiencing issues regarding all of the following over the past three months: a build-up of chest mucus, difficulty clearing chest mucus, breathlessness, and low energy levels
- Anyone who is generally healthy - does not live with any uncontrolled chronic disease
- Willing to refrain from taking any products, prescription medications, or supplements that target lung health, mucus, and energy levels during the test period
Key exclusion criteria (7 listed)
- Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including kidney disease, diabetes, cancer, mental health disorders, history of serious illness in the last three months, history of substance abuse, or planned surgery during the study period
- Anyone who drinks heavily (i.e. 8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men)
- Anyone with a copper sensitivity disorder (such as Wilson's disease or copper metabolism disorders)
- Anyone with kidney disease
- Anyone with diabetes
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| BetterLungs50 participants receive the BetterLungs Mullein + Chlorophyll supplement (ingredients: mullein leaf, chlorophyll, vegetable glycerin, purified water) taken once daily in the morning with the first meal of the day; 2 mL (two full droppers) mixed with 8 ounces of water for 60 days | Dietary supplement | BetterLungs Mullein |
| Placebo50 participants receive a matched placebo product (ingredients: moss coloring jungle green color, violet color, spirulina, vegetable glycerin, purified water) taken once daily in the morning with the first meal of the day; 2 mL (two full droppers) mixed with 8 ounces of water for 60 days; the taste and appearance of the placebo are matched to the active product | Dietary supplement | Placebo |
Primary outcome
Change in mucus clearance
Time frame: Baseline, Day 20, Day 40, and Day 60
Self-reported change in mucus clearance assessed via questionnaire
Change in respiratory symptoms
Time frame: Baseline, Day 20, Day 40, and Day 60
Self-reported change in respiratory symptoms assessed via questionnaire
6 secondary outcomes
Change in perceived mucus clearance
Time frame: Baseline, Day 20, Day 40, and Day 60
Change in energy levels
Time frame: Baseline, Day 20, Day 40, and Day 60
Change in shortness of breath
Time frame: Baseline, Day 20, Day 40, and Day 60
Change in breathing-related anxiety
Time frame: Baseline, Day 20, Day 40, and Day 60
Change in ease of breathing
Time frame: Baseline, Day 20, Day 40, and Day 60
Change in general well-being
Time frame: Baseline, Day 20, Day 40, and Day 60
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing BetterLungs in people with Mucus Clearance and Respiratory Symptoms, run by The Better Brand Inc. at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in mucus clearance (time frame: Baseline, Day 20, Day 40, and Day 60). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Aug 2026.