BPH With Urinary ObstructionHOLEP vs TURPNCT07741214
Low Power HOLEP Versus TURP
A study testing low power HOLEP and TURP in people with BPH With Urinary Obstruction and Prostatic Hyperplasia, run by Al-Azhar University at 1 site in Egypt.
Trial summary
Patients with obstructed flow due to BPH will be enrolled into 2 groups, group will undergo TURP and the other group will undergo Low power HOLEP Read more about this study
- Who is it for?
- Ages 50 years and older, men only
- Conditions the study is for
- BPH With Urinary Obstruction, Prostatic Hyperplasia
- What is being tested?
- low power HOLEP and TURP
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Aug 2026to 1 Nov 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 years and older
- Men only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- mens with LUTS due to obstructed prostate
Who cannot join
- stone bladder bladder cancer prostate cancer
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Low Power HOLEP Versus TURP in Management of BPH
Patients with obstructed flow due to BPH will be enrolled into 2 groups, group will undergo TURP and the other group will undergo Low power HOLEP
- Being tested
- low power HOLEP, TURP
- Keywords
- Low power HOLEP, TURP, HOLEP, BPH
- Medical subject headings
- Prostatic Hyperplasia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
low power HOLEPProcedure or surgery
Patients who will undergo transurethral resection of the prostate
TURPProcedure or surgery
Patients who will undergo transurethral resection of the prostate
| Study group | Role | What they receive |
|---|---|---|
| TURP | Active comparator | Not described Receives: Procedure: low power HOLEP; Procedure: TURP |
| LOW POWER HOLEP | Active comparator | patients who will undergo low power HOLEP Receives: Procedure: low power HOLEP; Procedure: TURP |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in The International Prostate Symptom Score (IPSS)
The International Prostate Symptom Score (IPSS) can be utilized to measure the severity of lower urinary tract symptoms.
It is a validated, reproducible scoring system to assess disease severity and response to therapy.
The IPSS is made up of 7 questions related to voiding symptoms. A score of 0 to 7 indicates mild symptoms, 8 to 19 indicates moderate symptoms and 20 to 35 indicates severe symptoms.
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Aug 2026
- Study start1 Aug 2026 (estimated)
- Primary completion1 Aug 2027 (estimated)
- Study completion1 Nov 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for BPH With Urinary ObstructionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Al-Azhar University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohamed Fawzy Abd Elfattah Salman, Al-Azhar University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07741214
- Sponsor's protocol ID
- Low power HOLEP versus TURP
- Acronym
- HOLEP vs TURP
- Status last verified
- Jul 2026
- First submitted
- 26 Jun 2026
- Last updated
- 3 Aug 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Low Power HOLEP Versus TURP in Management of BPH
- ClinicalTrials.gov ID
- NCT07741214
- Acronym / sponsor ID
- HOLEP vs TURP / Low power HOLEP versus TURP
- Keywords
- Low power HOLEP, TURP, HOLEP, BPH
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Al-Azhar UniversityUniversity, hospital or other
- Study start
- 1 Aug 2026 (estimated)
- Primary completion
- 1 Aug 2027 (estimated)
- Study completion
- 1 Nov 2027 (estimated)
- First posted
- 3 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Patients with obstructed flow due to BPH will be enrolled into 2 groups, group will undergo TURP and the other group will undergo Low power HOLEP
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| TURP | Active comparator | Procedure: low power HOLEP, Procedure: TURP |
| LOW POWER HOLEP | Active comparator | Procedure: low power HOLEP, Procedure: TURPpatients who will undergo low power HOLEP |
Who may qualify
- Ages
- 50 years and older
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- mens with LUTS due to obstructed prostate
Key exclusion criteria (1 listed)
- stone bladder bladder cancer prostate cancer
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| low power HOLEPPatients who will undergo transurethral resection of the prostate | Procedure or surgery | LOW POWER HOLEP, TURP |
| TURPPatients who will undergo transurethral resection of the prostate | Procedure or surgery | LOW POWER HOLEP, TURP |
Primary outcome
Change in The International Prostate Symptom Score (IPSS)
Time frame: 6 months
The International Prostate Symptom Score (IPSS) can be utilized to measure the severity of lower urinary tract symptoms. It is a validated, reproducible scoring system to assess disease severity and response to therapy. The IPSS is made up of 7 questions related to voiding symptoms. A score of 0 to 7 indicates mild symptoms, 8 to 19 indicates moderate symptoms and 20 to 35 indicates severe symptoms.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing low power HOLEP and TURP in people with BPH With Urinary Obstruction and Prostatic Hyperplasia, run by Al-Azhar University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 3 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in The International Prostate Symptom Score (IPSS) (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Aug 2026.