Glenohumeral ArthritisGOATNCT07744542
Glenohumeral OsteoArthritis Therapy Trial
A study testing Physical therapy and Home physical therapy in people with Glenohumeral Arthritis and Shoulder Arthritis Osteoarthritis, run by State University of New York at Buffalo at 1 site in United States.
Trial summary
Arthritis of the shoulder glenohumeral joint is a growing problem in an aging population. Treatment options for glenohumeral arthritis can be grouped into three main categories: 1) shoulder replacement surgery, 2) injections (corticosteroid, hyaluronic acid and PRP) and physical therapy (PT). Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Glenohumeral Arthritis, Shoulder Arthritis Osteoarthritis
- What is being tested?
- Physical therapy and Home physical therapy
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 125 participants
- Where
- 1 siteUnited States
- Study dates
- 17 Jun 2026to 30 Jun 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patient diagnosed with glenohumeral arthritis
- Patient > 18 years of age (adults)
- Patient provided written informed consent for study participation with IRB approved consent form
- Patient is willing and able to comply with scheduled clinical and radiographic evaluations and physical therapy regimen
Who cannot join
- -Have had corticosteroid injections in the affected shoulder(s) within 6 weeks of starting physical therapy.
- Those that have glenohumeral arthritis that is inflammatory, post traumatic or related to rotator cuff tear arthropathy in nature
- Have avascular necrosis of the glenohumeral joint
- Have failed a course of 6 weeks of physical therapy within the last year
- Have had surgery on the symptomatic shoulder in the past year
- Daily use of opioid (excluding tramadol or codeine).
Show all 11Show fewer
- Have dementia
- Currently in a physical therapy program for more than 2 weeks
- Have planned total shoulder arthroplasty in the next 6 months.
- Live in a nursing home
- Additionally special populations listed below such as pregnant women, and prisoners will be excluded.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
UBMD Orthopaedics & Sports Medicine
Buffalo, New York, 14221-2108
About this study
Official title: A Prospective Randomized Trial Comparing Physical Therapy or Home Exercise With No Treatment for Patients With Glenohumeral Osteoarthritis
Arthritis of the shoulder glenohumeral joint is a growing problem in an aging population. Treatment options for glenohumeral arthritis can be grouped into three main categories: 1) shoulder replacement surgery, 2) injections (corticosteroid, hyaluronic acid and PRP) and physical therapy (PT). Surgery comes with risks and the potential for implant failure or revision over time. Therefore, it is typical for doctors to prescribe injections and/or PT before discussing surgery. Sometimes, insurance companies will require PT before considering a shoulder operation. It is unknown if PT is effective for improving function or pain with patients with glenohumeral arthritis. The aim of this study is to compare pain and functional outcomes after undergoing a 12 week PT program, at home PT exercises or delaying conservative treatment.
- Being tested
- Physical therapy, Home physical therapy
- Keywords
- Shoulder arthritis, Physical therapy, Home Therapy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Physical therapyBehavioural
12 weeks of designated physical therapy focused on improving shoulder strength and range of motion
Home physical therapyBehavioural
12 weeks of home therapy program focused on improving shoulder strength and range of motion
| Study group | Role | What they receive |
|---|---|---|
| Physical Therapy | Experimental | 12 weeks of designated physical therapy focused on improving shoulder strength and range of motion Receives: Behavioral: Physical therapy |
| Home Therapy | Experimental | 12 weeks of home therapy program focused on improving shoulder strength and range of motion Receives: Behavioral: Home physical therapy |
| Control Group | No intervention | Subjects continue with coping mechanisms for 12 week period, no intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual analog scale (VAS)
measures pain from 0 being none and 10 as the worst pain ever felt.
Measured: Time 0, 6 weeks, 12 weeks, 1 year
American Shoulder and Elbow Surgeons (ASES)
This score is a 100-point shoulder evaluation tool divided evenly into a pain subscore (50 points) and an activities of daily living (ADL) function subscore (50 points). Higher scores indicate less pain and better shoulder function.
Measured: Time 0, 6 weeks, 12 weeks, 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Aug 2026
- Study start17 Jun 2026
- Primary completion30 Jun 2028 (estimated)
- Study completion30 Jun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Glenohumeral ArthritisStudies of the same condition, open and under way.
- More trials run by State University of New York at BuffaloThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomized Controlled Trial
- Masking
- None (open label)
- Enrolment
- 125 participants (estimated)
Sponsor and investigators
- Lead sponsor
- State University of New York at Buffalo
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Matthew DiPaola, MD, State University of New York at Buffalo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07744542
- Sponsor's protocol ID
- IRB ID: STUDY00009760
- Acronym
- GOAT
- Status last verified
- Jun 2026
- First submitted
- 17 Jul 2026
- Last updated
- 4 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Prospective Randomized Trial Comparing Physical Therapy or Home Exercise With No Treatment for Patients With Glenohumeral Osteoarthritis
- ClinicalTrials.gov ID
- NCT07744542
- Acronym / sponsor ID
- GOAT / IRB ID: STUDY00009760
- Keywords
- Shoulder arthritis, Physical therapy, Home Therapy
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 125 participants (estimated)
- Lead sponsor
- State University of New York at BuffaloUniversity, hospital or other
- Study start
- 17 Jun 2026 (actual)
- Primary completion
- 30 Jun 2028 (estimated)
- Study completion
- 30 Jun 2028 (estimated)
- First posted
- 4 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Arthritis of the shoulder glenohumeral joint is a growing problem in an aging population. Treatment options for glenohumeral arthritis can be grouped into three main categories: 1) shoulder replacement surgery, 2) injections (corticosteroid, hyaluronic acid and PRP) and physical therapy (PT). Surgery comes with risks and the potential for implant failure or revision over time. Therefore, it is typical for doctors to prescribe injections and/or PT before discussing surgery. Sometimes, insurance companies will require PT before considering a shoulder operation. It is unknown if PT is effective for improving function or pain with patients with glenohumeral arthritis. The aim of this study is to compare pain and functional outcomes after undergoing a 12 week PT program, at home PT exercises or delaying conservative treatment.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- Randomized Controlled Trial
| Arm | Type | Receives |
|---|---|---|
| Physical Therapy | Experimental | Behavioral: Physical therapy12 weeks of designated physical therapy focused on improving shoulder strength and range of motion |
| Home Therapy | Experimental | Behavioral: Home physical therapy12 weeks of home therapy program focused on improving shoulder strength and range of motion |
| Control Group | No intervention | –Subjects continue with coping mechanisms for 12 week period, no intervention |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Patient diagnosed with glenohumeral arthritis
- Patient > 18 years of age (adults)
- Patient provided written informed consent for study participation with IRB approved consent form
- Patient is willing and able to comply with scheduled clinical and radiographic evaluations and physical therapy regimen
Key exclusion criteria (11 listed)
- -Have had corticosteroid injections in the affected shoulder(s) within 6 weeks of starting physical therapy.
- Those that have glenohumeral arthritis that is inflammatory, post traumatic or related to rotator cuff tear arthropathy in nature
- Have avascular necrosis of the glenohumeral joint
- Have failed a course of 6 weeks of physical therapy within the last year
- Have had surgery on the symptomatic shoulder in the past year
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Physical therapy12 weeks of designated physical therapy focused on improving shoulder strength and range of motion | Behavioural | Physical Therapy |
| Home physical therapy12 weeks of home therapy program focused on improving shoulder strength and range of motion | Behavioural | Home Therapy |
Primary outcome
Visual analog scale (VAS)
Time frame: Time 0, 6 weeks, 12 weeks, 1 year
measures pain from 0 being none and 10 as the worst pain ever felt.
American Shoulder and Elbow Surgeons (ASES)
Time frame: Time 0, 6 weeks, 12 weeks, 1 year
This score is a 100-point shoulder evaluation tool divided evenly into a pain subscore (50 points) and an activities of daily living (ADL) function subscore (50 points). Higher scores indicate less pain and better shoulder function.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Physical therapy and Home physical therapy in people with Glenohumeral Arthritis and Shoulder Arthritis Osteoarthritis, run by State University of New York at Buffalo at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 4 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual analog scale (VAS) (time frame: Time 0, 6 weeks, 12 weeks, 1 year). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Aug 2026.