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Groin PainNCT07750327

An Exercise-based Rehabilitation Program for a Recreational Long-distance Runner With Long-standing Groin Pain

A study testing A pain-guided rehabilitation program in people with Groin Pain, run by University of West Attica at 1 site in Greece.

Enrolling by invitation

Enrolling by invitation. The study team selects and invites participants, usually from an existing group of patients.

Sites and contacts
Official record
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Trial summary

Groin injuries are among the most common injuries in sports that require changes of directions, shooting, passing etc, and are presented both as acute and long-standing. Although there are many exercise-based rehabilitation programs for long-standing groin pain in athletes, there is still the need for a more flexible… Read more about this study

Who is it for?
Ages 18 years and older, men only
Conditions the study is for
Groin Pain
What is being tested?
A pain-guided rehabilitation program
Could I receive a placebo?
No, everyone receives an active treatment
How many people
1 participants
Where
1 siteGreece
Study dates
22 Jul 2026to 10 Oct 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • Men only
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Male or female long-distance runner
  • Long-standing groin pain (≥ 6 weeks)
  • ≥ 18 years

Who cannot join

  • Neurological or musculoskeletal condition which do not allow the athlete to perform the strength testing and the program intervention.

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Greece1 site
  • University of West Attica

    Athens, Athens, 12243

Other trials in Greece

About this study

Official title: A Pain-guided Rehabilitation Program in a Recreational Long-distance Runner With Long-standing Groin Pain: A Single-case Experimental Study

Groin injuries are among the most common injuries in sports that require changes of directions, shooting, passing etc, and are presented both as acute and long-standing. Although there are many exercise-based rehabilitation programs for long-standing groin pain in athletes, there is still the need for a more flexible pain-guided program based on specific progression and return to sport criteria. In addition, there is no much focus on less demanding sports such as track and field. The current study introduces a pain-guided rehabilitation program for a long-distance runner with long-standing groin pain.

Read the detailed description

A 38-year-old male recreational runner reported pain in his right groin (adductor and lower abdomen area). The mean pain level reported was 2 in a numeric pain rating scale (NPRS) of 0-10, which occasionally increased to 3. Aggravating exercises included straight abdominal sit-ups, sliding hip exercise, and hip adductor squeeze at 45 degrees. In addition, symptoms were provoked by laughing and sexual intercourse. The initial onset of pain was nine years before the athlete contacted the research team seeking assistance (2017). Pain was resolved after two years (2019) of systematic resistance training, but reappeared five years later. The athlete did not report any specific mechanism of the initial injury, but described an insidious pain presented during an intense running period. Although the athlete had a number of physiotherapy sessions within the last year, including electrotherapeutic modalities (TENS, radiofrequency therapy) and massage, there was no improvement of the pain in the groin area. His weekly training schedule during the month before the clinical examination included one running session (10 km), one upper limb resistance training session, and one groin-specific resistance training session. The athlete reported no previous musculoskeletal injuries, while no radiological examination had been performed.

The program will comprise two distinct phases. Phase A will consist of a baseline monitoring period, during which the athlete will exclusively perform adductor strength testing without any exercise intervention. This phase will serve to establish a stable baseline strength level before the athlete starts the rehabilitation program. Transition to Phase B will be determined by the strength variance between sessions; if there is a difference of ≤ 10% across the first three sessions for each leg, the athlete will move to Phase B at the fourth week. Otherwise, further testing sessions will be needed before the athlete starts the program, provided that a difference of ≤ 10% is achieved across three consecutive testing sessions.

In phase B, the athlete will perform a pain-guided progressive rehabilitation program which comprises three distinct components: anterior chain, posterior chain, and functional training. Anterior chain includes exercises relevant to the groin (adductor muscles, hip flexor muscles, and trunk muscles), posterior chain exercises targeting muscle groups not related to the injured area (hip extensor and abductor muscles, knee extensor and flexor muscles, and ankle plantar flexor muscles), and functional exercises related to the sport (hopping and jumping and linear running). The athlete will be allowed to choose between a number of exercises for each muscle group included in anterior and posterior chain components. Weekly training frequency will vary between 3 to 6 sessions, including 3 anterior chain sessions, 2-3 posterior chain sessions, and 2-3 functional training sessions, depending on the athlete's availability. Once specific return to sport criteria are fulfilled (Appendix II), Phase B will be completed.

During the rehabilitation period, the athlete will not be allowed to participate in any other form of training outside the predefined protocol. Additional upper limb exercises and any therapeutic options will be allowed after discussion with the research team, provided they do not interfere with the rehabilitation protocol implementation.

Exercise progression

Anterior chain exercise progression will be determined by the pain level, while no pain will be allowed during posterior chain exercises. In exercises where pain is present, a "pain-controlled repetition maximum" (PRM) approach will be followed. The athlete will perform each set until failure keeping pain at 2/10. If pain is more than 2, the athlete will have to reduce the load. If pain is less than 2, the athlete will have to increase the load. If the athlete experiences pain > 2/10 longer than 24 hours after training, he will be advised to return to the previous training level until pain returns to normal. In exercises where pain is absent, a repetition maximum (RM) approach will be followed, during which the athlete will perform 8-10 repetitions keeping 3 repetitions in reserve (RIR) in each set.

The rehabilitation protocol will be performed as an unsupervised intervention, reflecting pragmatic clinical scenarios where recreational athletes lack access to clinical supervision due to financial or other constraints. However, adherence, exercise execution, or any difficulties during rehabilitation will be addressed during weekly meetings with the physiotherapist performing strength testing. During these meetings, the physiotherapist will ensure that exercises are executed with proper form and any queries by the athlete are answered. In addition, prior to initiation of the rehabilitation the athlete will be provided with documents including detailed exercise descriptions, ensuring understanding and proper execution.

Conditions
Groin Pain
Being tested
A pain-guided rehabilitation program
Keywords
groin pain, rehabilitation, exercise training, distance running

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • A pain-guided rehabilitation programOther

    A pain-guided unsupervised rehabilitation program

Study groups in NCT07750327
Study groupRoleWhat they receive
A single treatmentExperimentalNot described
Receives: Other: A pain-guided rehabilitation program

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Return to sport time

    The time to return to sport is defined as the total number of weeks recorded from the date of the first rehabilitation session to the day the athlete fulfils the return to sport criteria.

    Measured: Return to sport time is determined as the time (number of days) from the first rehabilitation session to the day the athlete fulfils the return to sport criteria. The estimated time of the rehabilitation completion is up to 12 weeks.

  2. Adductor muscle strength

    Maximum eccentric and isometric adductor muscle strength will be assessed with a mid-range unilateral supine isometric adduction test and an outer-range unilateral supine eccentric adduction test, following standardized procedures which have demonstrated good intra-tester reliability [EHAD ICC 0.91 (0.70-0.98), SEM: 6.3%, IHAD ICC 0.78 (0.30-0.95), SEM: 7.3%]. Strength values will be normalized to the athlete's body weight and recorded as Nm/kg.

    Measured: Eccentric and isometric adductor muscle strength will be tested on weekly basis from baseline to the completion of the treatment. The estimated number of testing sessions throughout the intervention is 12.

  3. Tissue tolerance

    Tissue tolerance is defined as the maximum adductor strength generated when the athlete reaches a pain level of 2/10 of the NPRS, and will be assessed with the use of a bilateral squeeze test at 0° of hip and knee flexion. Strength values will be normalized to the athlete's body weight and recorded as Nm/kg.

    Measured: Tissue tolerance will be evaluated on weekly basis from baseline to the completion of the treatment. The estimated number of testing sessions throughout the intervention is 12.

Secondary outcomes (2)
  1. Hip-related quality of life

    Hip-related quality of life will be evaluated with the use of the Greek version of the 12-item International Hip Outcome Tool (iHOT-12). The iHOT-12 is a validated tool which assesses domains including symptoms and functional limitations, sport and recreational activities, job-related concerns, and social, emotional, and lifestyle concerns. Hip-related quality of life will be evaluated baseline and at the completion of the rehabilitation with the use of the 12-item International Hip Outcome Tool (iHOT-12). Score range: 0-100, with higher scores indicating a better outcome.

    Measured: Hip-related quality of life will be evaluated baseline and at the end of the rehabilitation. The estimated time for the intervention completion is 12 weeks.

  2. Athlete's recovery perception

    Subjective overall recovery perception will be evaluated via the validated Greek version of the Global Perceived Effect (GPE) scale. Athlete's recovery perception will be evaluated on weekly basis until the completion of the rehabilitation with the use of the Global Perceived Effect (GPE) scale. Score range: -3 to 3, with higher scores indicating a better outcome.

    Measured: Subjective overall recovery perception will be evaluated on a weekly basis. Although the overall duration of the intervention cannot be defined due to the criteria-based nature of the progression, the estimated time for completion is 12 weeks.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted6 Aug 2026
  2. Study start22 Jul 2026
  3. Primary completion30 Sep 2026 (estimated)
  4. Study completion10 Oct 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Model description
Single-case experimental study
Masking
None (open label)
Enrolment
1 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07750327
Sponsor's protocol ID
68969/07-07-2026
Status last verified
Sep 2026
First submitted
21 Jul 2026
Last updated
15 Sep 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes: Strength raw data

Publications

  • Kontakiotis, N., Gioftsos, G. Translation into Greek, cross-cultural adaptation and test-retest reliability of the Global Perceived Effect Scale for use with patients with sciatica. Archives of Hellenic Medicine. 2022;39(3):381-7.

  • Griffin DR, Parsons N, Mohtadi NG, Safran MR; Multicenter Arthroscopy of the Hip Outcomes Research Network. A short version of the International Hip Outcome Tool (iHOT-12) for use in routine clinical practice. Arthroscopy. 2012 May;28(5):611-6; quiz 616-8. doi: 10.1016/j.arthro.2012.02.027.

    PubMed 22542434
  • Stasi S, Stamou M, Papathanasiou G, Frantzeskaki P, Kanavas E, Evaggelou-Sossidis G, Gouskos A, Palantzas A, Poursanidis K, Macheras GA. International Hip Outcome Tool (12-items) as health-related quality-of-life measure in osteoarthritis: validation of Greek version. J Patient Rep Outcomes. 2020 May 27;4(1):41. doi: 10.1186/s41687-020-00207-8.

    PubMed 32462334
  • Light N, Thorborg K. The precision and torque production of common hip adductor squeeze tests used in elite football. J Sci Med Sport. 2016 Nov;19(11):888-892. doi: 10.1016/j.jsams.2015.12.009. Epub 2015 Dec 12.

    PubMed 26750142
  • Thorborg K, Petersen J, Magnusson SP, Holmich P. Clinical assessment of hip strength using a hand-held dynamometer is reliable. Scand J Med Sci Sports. 2010 Jun;20(3):493-501. doi: 10.1111/j.1600-0838.2009.00958.x. Epub 2009 Jun 23.

    PubMed 19558384
  • Borg E, Borg G, Larsson K, Letzter M, Sundblad BM. An index for breathlessness and leg fatigue. Scand J Med Sci Sports. 2010 Aug;20(4):644-50. doi: 10.1111/j.1600-0838.2009.00985.x. Epub 2009 Jul 2.

    PubMed 19602182
  • Serner A, Weir A, Tol JL, Thorborg K, Lanzinger S, Otten R, Holmich P. Return to Sport After Criteria-Based Rehabilitation of Acute Adductor Injuries in Male Athletes: A Prospective Cohort Study. Orthop J Sports Med. 2020 Jan 29;8(1):2325967119897247. doi: 10.1177/2325967119897247. eCollection 2020 Jan.

    PubMed 32064292
  • Holmich P, Holmich LR, Bjerg AM. Clinical examination of athletes with groin pain: an intraobserver and interobserver reliability study. Br J Sports Med. 2004 Aug;38(4):446-51. doi: 10.1136/bjsm.2003.004754.

    PubMed 15273182
  • Serner A, Reboul G, Lichau O, Weir A, Heijboer W, Vuckovic Z, Boudreau SA. Digital body mapping of pain quality and distribution in athletes with longstanding groin pain. Sci Rep. 2022 Jun 13;12(1):9789. doi: 10.1038/s41598-022-13847-1.

    PubMed 35697738
  • Weir A, Brukner P, Delahunt E, Ekstrand J, Griffin D, Khan KM, Lovell G, Meyers WC, Muschaweck U, Orchard J, Paajanen H, Philippon M, Reboul G, Robinson P, Schache AG, Schilders E, Serner A, Silvers H, Thorborg K, Tyler T, Verrall G, de Vos RJ, Vuckovic Z, Holmich P. Doha agreement meeting on terminology and definitions in groin pain in athletes. Br J Sports Med. 2015 Jun;49(12):768-74. doi: 10.1136/bjsports-2015-094869.

    PubMed 26031643
  • Yousefzadeh A, Shadmehr A, Olyaei GR, Naseri N, Khazaeipour Z. The Effect of Therapeutic Exercise on Long-Standing Adductor-Related Groin Pain in Athletes: Modified Holmich Protocol. Rehabil Res Pract. 2018 Mar 12;2018:8146819. doi: 10.1155/2018/8146819. eCollection 2018.

    PubMed 29721339
  • Paajanen H, Brinck T, Hermunen H, Airo I. Laparoscopic surgery for chronic groin pain in athletes is more effective than nonoperative treatment: a randomized clinical trial with magnetic resonance imaging of 60 patients with sportsman's hernia (athletic pubalgia). Surgery. 2011 Jul;150(1):99-107. doi: 10.1016/j.surg.2011.02.016. Epub 2011 May 5.

    PubMed 21549403
  • Weir A, Jansen JA, van de Port IG, Van de Sande HB, Tol JL, Backx FJ. Manual or exercise therapy for long-standing adductor-related groin pain: a randomised controlled clinical trial. Man Ther. 2011 Apr;16(2):148-54. doi: 10.1016/j.math.2010.09.001. Epub 2010 Oct 16.

    PubMed 20952244
  • Kachingwe AF, Grech S. Proposed algorithm for the management of athletes with athletic pubalgia (sports hernia): a case series. J Orthop Sports Phys Ther. 2008 Dec;38(12):768-81. doi: 10.2519/jospt.2008.2846.

    PubMed 19047766
  • Holmich P, Uhrskou P, Ulnits L, Kanstrup IL, Nielsen MB, Bjerg AM, Krogsgaard K. Effectiveness of active physical training as treatment for long-standing adductor-related groin pain in athletes: randomised trial. Lancet. 1999 Feb 6;353(9151):439-43. doi: 10.1016/S0140-6736(98)03340-6.

    PubMed 9989713

Questions about this trial

What is this clinical trial studying?

A study testing A pain-guided rehabilitation program in people with Groin Pain, run by University of West Attica at 1 site in Greece.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: enrolling by invitation, as of the sponsor's last update on 15 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Greece. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Return to sport time (time frame: Return to sport time is determined as the time (number of days) from the first rehabilitation session to the day the athlete fulfils the return to sport criteria. The estimated time of the rehabilitation completion is up to 12 weeks.). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07750327, which also lists 20 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Sep 2026.

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