Cardiac SurgeryNCT07755254
Frailty and Dependency in Older Adults Undergoing Cardiac Surgery
An observational study of Cardiac Surgery and Nursing Care, run by Aydin Adnan Menderes University at 1 site in Turkey (Türkiye).
Trial summary
Frailty and dependency are common conditions among older adults undergoing cardiac surgery and may adversely affect postoperative recovery and readiness for hospital discharge. Early identification of these conditions before surgery may facilitate individualized perioperative care and improve postoperative outcomes. Read more about this study
- Who is it for?
- Ages 65 to 85 years
- Conditions the study is for
- Cardiac Surgery, Nursing Care, Perioperative Care
- How many people
- 187 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Jun 2025to 15 Dec 2026
- How long will I take part?
- 6 Days
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 85 years
- All sexes
- No healthy volunteers
- Older adult
Study population: Older adults aged 65-85 years who are admitted to the Cardiovascular Surgery Clinic of Aydın Adnan Menderes University Research and Application Hospital for elective cardiac surgery and meet the eligibility criteria will be consecutively enrolled in the study.
Who may be able to join
- Age between 65 and 85 years
- Scheduled to undergo cardiac surgery (coronary artery bypass graft surgery,
- Bentall procedure, heart valve surgery, or aneurysm surgery)
- No surgical history within the previous two months
- Able to read and write Turkish
- No hearing impairment
- Willing to participate and provide written informed consent
Who cannot join
- Surgery within the previous eight weeks
- Diagnosis of a psychiatric disorder
- Withdrawal of consent during the study
- Incomplete study questionnaires
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Aydın Adnan Menderes University
Aydin, Zafer Mahallesi, 09010
About this study
Official title: Effects of Preoperative Frailty and Dependency on Postoperative Recovery and Readiness for Hospital Discharge in Older Adults Undergoing Cardiac Surgery
Frailty and dependency are common conditions among older adults undergoing cardiac surgery and may adversely affect postoperative recovery and readiness for hospital discharge. Early identification of these conditions before surgery may facilitate individualized perioperative care and improve postoperative outcomes. This observational study aims to investigate the effects of preoperative frailty and dependency on postoperative recovery and readiness for hospital discharge in older patients undergoing cardiac surgery. Data will be collected before surgery and at hospital discharge using validated assessment instruments. The findings are expected to support preoperative risk assessment and contribute to individualized nursing care planning for older cardiac surgery patients.
Read the detailed description
The growing elderly population has resulted in an increasing number of older adults undergoing cardiac surgery. Age-related physiological decline, multiple comorbidities, polypharmacy, and reduced physiological reserve increase vulnerability to adverse postoperative outcomes. Frailty and dependency are common geriatric conditions that may influence postoperative recovery, functional status, and readiness for discharge.
Frailty is characterized by increased vulnerability to stressors because of diminished physiological reserve, whereas dependency reflects limitations in performing activities of daily living independently. Identifying these conditions before surgery may facilitate early recognition of patients at risk for delayed recovery and inadequate discharge readiness.
This single-center observational study will be conducted in the Cardiovascular Surgery Clinic of Aydın Adnan Menderes University Research and Application Hospital. Patients aged 65-85 years scheduled to undergo cardiac surgery will be recruited consecutively. Before surgery, participants will complete the Patient Information Form, the FRAIL Scale, and the Katz Activities of Daily Living Scale. At hospital discharge, postoperative recovery will be evaluated using the Postoperative Recovery Index, and readiness for hospital discharge will be assessed using the Readiness for Hospital Discharge Scale-Short Form.
The primary objective is to determine the effects of preoperative frailty and dependency on postoperative recovery and readiness for hospital discharge among older adults undergoing cardiac surgery. The findings are expected to improve perioperative risk assessment and contribute to evidence-based nursing care planning.
- Conditions
- Cardiac Surgery, Nursing Care, Perioperative Care
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Recovery
Postoperative recovery will be assessed using the Postoperative Recovery Index. The scale consists of 5 subdimensions and 25 items. The subdimensions are: psychological symptoms, physical activities, general symptoms, bowel symptoms, and desire symptoms. When determining subdimension scores, the scores of the relevant items are summed and their arithmetic mean is calculated. For the total score, all items are summed and their arithmetic mean is calculated. High scores on the index reflect greater difficulties in postoperative recovery, while low scores indicate easier postoperative recovery.
Measured: At hospital discharge (approximately postoperative day 6)
Readiness for Hospital Discharge
Readiness for hospital discharge will be assessed using the Readiness for Hospital Discharge Scale-Short Form. The scale consists of 8 questions and 4 sub-dimensions: personal situation, knowledge, coping, and expected support. The questions are evaluated on a scale of '0=not ready' to '10=completely ready'. A total score of 0-80 can be obtained from the scale based on the answers given to the questions; a higher score indicates a higher level of readiness for discharge. On the scale dimensions, a score of 7 and above indicates readiness for discharge, while a score below 7 indicates readiness for discharge.
Measured: At hospital discharge (approximately postoperative day 6)
Secondary outcomes (2)
Frailty
Frailty will be assessed using the FRAIL Scale. The scale consists of five items evaluating fatigue, resistance, ambulation, illnesses, and weight loss. Higher scores indicate greater frailty. The minimum score obtainable from the scale is between "0" (zero) and "5" (five). There is no cutoff score for the scale; it is interpreted that an increase in the score indicates an increase in the level of vulnerability.
Measured: One day before surgery (Baseline)
Dependency in Activities of Daily Living
Dependency will be assessed using the Katz Activities of Daily Living Scale. The instrument evaluates independence in six basic daily living activities. As the scores obtained from the scale increase, it is interpreted as an increase in difficulty in performing daily living activities and an increase in dependence. Based on the scores obtained from the scale, 0-2 is classified as dependent, 3-4 as semi-dependent, and 5-6 as independent.
Measured: One day before surgery (Baseline)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Aug 2026
- Study start15 Jun 2025
- Primary completion15 Aug 2026 (estimated)
- Study completion15 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cardiac SurgeryStudies of the same condition, open and under way.
- More trials run by Aydin Adnan Menderes UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 187 participants (estimated)
- Target duration
- 6 Days
Sponsor and investigators
- Lead sponsor
- Aydin Adnan Menderes University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ezgi Arslan, Aydin Adnan Menderes University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07755254
- Sponsor's protocol ID
- Cardiac Surgery and Frailty
- Status last verified
- Aug 2026
- First submitted
- 5 Aug 2026
- Last updated
- 12 Aug 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The data sets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.
Study at a glance
From the registry record, last updated by the sponsor on 12 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Preoperative Frailty and Dependency on Postoperative Recovery and Readiness for Hospital Discharge in Older Adults Undergoing Cardiac Surgery
- ClinicalTrials.gov ID
- NCT07755254
- Acronym / sponsor ID
- Cardiac Surgery and Frailty
- Conditions
- Cardiac Surgery, Nursing Care, Perioperative Care
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 187 participants (estimated)
- Lead sponsor
- Aydin Adnan Menderes UniversityUniversity, hospital or other
- Study start
- 15 Jun 2025 (actual)
- Primary completion
- 15 Aug 2026 (estimated)
- Study completion
- 15 Dec 2026 (estimated)
- First posted
- 10 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Frailty and dependency are common conditions among older adults undergoing cardiac surgery and may adversely affect postoperative recovery and readiness for hospital discharge. Early identification of these conditions before surgery may facilitate individualized perioperative care and improve postoperative outcomes. This observational study aims to investigate the effects of preoperative frailty and dependency on postoperative recovery and readiness for hospital discharge in older patients undergoing cardiac surgery. Data will be collected before surgery and at hospital discharge using validated assessment instruments. The findings are expected to support preoperative risk assessment and contribute to individualized nursing care planning for older cardiac surgery patients.
Detailed description
The growing elderly population has resulted in an increasing number of older adults undergoing cardiac surgery. Age-related physiological decline, multiple comorbidities, polypharmacy, and reduced physiological reserve increase vulnerability to adverse postoperative outcomes. Frailty and dependency are common geriatric conditions that may influence postoperative recovery, functional status, and readiness for discharge.
Frailty is characterized by increased vulnerability to stressors because of diminished physiological reserve, whereas dependency reflects limitations in performing activities of daily living independently. Identifying these conditions before surgery may facilitate early recognition of patients at risk for delayed recovery and inadequate discharge readiness.
This single-center observational study will be conducted in the Cardiovascular Surgery Clinic of Aydın Adnan Menderes University Research and Application Hospital. Patients aged 65-85 years scheduled to undergo cardiac surgery will be recruited consecutively. Before surgery, participants will complete the Patient Information Form, the FRAIL Scale, and the Katz Activities of Daily Living Scale. At hospital discharge, postoperative recovery will be evaluated using the Postoperative Recovery Index, and readiness for hospital discharge will be assessed using the Readiness for Hospital Discharge Scale-Short Form.
The primary objective is to determine the effects of preoperative frailty and dependency on postoperative recovery and readiness for hospital discharge among older adults undergoing cardiac surgery. The findings are expected to improve perioperative risk assessment and contribute to evidence-based nursing care planning.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Target follow-up
- 6 Days
Who may qualify
- Ages
- 65 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- Older adults aged 65-85 years who are admitted to the Cardiovascular Surgery Clinic of Aydın Adnan Menderes University Research and Application Hospital for elective cardiac surgery and meet the eligibility criteria will be consecutively enrolled in the study.
Key inclusion criteria (7 listed)
- Age between 65 and 85 years
- Scheduled to undergo cardiac surgery (coronary artery bypass graft surgery,
- Bentall procedure, heart valve surgery, or aneurysm surgery)
- No surgical history within the previous two months
- Able to read and write Turkish
Key exclusion criteria (4 listed)
- Surgery within the previous eight weeks
- Diagnosis of a psychiatric disorder
- Withdrawal of consent during the study
- Incomplete study questionnaires
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Postoperative Recovery
Time frame: At hospital discharge (approximately postoperative day 6)
Postoperative recovery will be assessed using the Postoperative Recovery Index. The scale consists of 5 subdimensions and 25 items. The subdimensions are: psychological symptoms, physical activities, general symptoms, bowel symptoms, and desire symptoms. When determining subdimension scores, the scores of the relevant items are summed and their arithmetic mean is calculated. For the total score, all items are summed and their arithmetic mean is calculated. High scores on the index reflect greater difficulties in postoperative recovery, while low scores indicate easier postoperative recovery.
Readiness for Hospital Discharge
Time frame: At hospital discharge (approximately postoperative day 6)
Readiness for hospital discharge will be assessed using the Readiness for Hospital Discharge Scale-Short Form. The scale consists of 8 questions and 4 sub-dimensions: personal situation, knowledge, coping, and expected support. The questions are evaluated on a scale of '0=not ready' to '10=completely ready'. A total score of 0-80 can be obtained from the scale based on the answers given to the questions; a higher score indicates a higher level of readiness for discharge. On the scale dimensions, a score of 7 and above indicates readiness for discharge, while a score below 7 indicates readiness for discharge.
2 secondary outcomes
Frailty
Time frame: One day before surgery (Baseline)
Dependency in Activities of Daily Living
Time frame: One day before surgery (Baseline)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Aug 2026.
- Individual participant dataSharing planned: Yes. The data sets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cardiac Surgery and Nursing Care, run by Aydin Adnan Menderes University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 12 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Recovery (time frame: At hospital discharge (approximately postoperative day 6)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Aug 2026.