Control Condition(LYFE-III)NCT07761052
The Latino Youth and Family Empowerment Study - III (LYFE-III): Bringing to Scale a Culturally-Adapted and Evidence-Based Intervention for Latino Families
A study testing Parenting Intervention in people with Control Condition and Parent, run by Texas A&M University.
Trial summary
The objective of this study is to harness digital technology to bring to scale a culturally adapted and evidence-based parenting intervention for Latinos (Nuestras Familias: Andando Entre Culturas). Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Control Condition, Parent
- What is being tested?
- Parenting Intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 200 participants
- Where
- No sites listed yet
- Study dates
- Sep 2026to 31 Jul 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- The family identifies as Latino or Hispanic.
- The family includes a child in the sixth or seventh grade.
- The child is newly enrolled in or has recently begun receiving services through Breakthrough Central Texas.
- At least one parent or primary caregiver speaks Spanish.
- A parent or primary caregiver and the participating child are willing to complete study assessments.
- The parent or primary caregiver agrees that the family may be randomly assigned to either the LYFE-III intervention group or the services-as-usual group.
- The parent or primary caregiver is willing to complete the online parenting program if assigned to the LYFE-III intervention group.
- The parent or legal guardian is willing to provide informed consent, and the child is willing to provide assent.
Who cannot join
- The parent or primary caregiver is currently participating in another parenting education or parent-training program.
- A participating parent or child has an active, severe mental health condition, such as schizophrenia or another psychotic disorder, that would make participation in a preventive parenting program inappropriate.
- A participating parent or child has mental health or substance-use needs that, after review by a study psychologist, require a higher level of care than the LYFE-III prevention program provides.
- The parent or child is unable or unwilling to complete the study procedures or participate in the assigned study condition.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
The objective of this study is to harness digital technology to bring to scale a culturally adapted and evidence-based parenting intervention for Latinos (Nuestras Familias: Andando Entre Culturas). The Latino Youth and Family Empowerment - III study (LYFE-III) proposed here will adapt, scale, and evaluate the efficacy of an online version of Nuestras Familias with Latino parents and youth in a randomized controlled trial (RCT). The specific aims are as follows:
Aim 1. To adapt the Nuestras Familias intervention to an online format that can be widely accessed by underserved Latino families. This process includes intervention refinement, enhancing efficiency, and manualization of intervention content
Aim 2. Conduct a small randomized controlled pilot trial to (a) test the online program's promise while evaluating changes in target mechanisms of action (i.e., parenting practices) and their subsequent effects on youth mental health outcomes; and (b) to evaluate the feasibility, appropriateness, and acceptability of the online version of the Nuestras Familias intervention.
Read the detailed description
The Latino Youth and Family Empowerment Study-III (LYFE-III) is designed to adapt and pilot test Nuestras Familias: Andando Entre Culturas, a culturally adapted, evidence-based parenting intervention for Latino families. Nuestras Familias integrates principles from parent management training, social learning theory, and ecodevelopmental theory. The program is intended to strengthen parenting practices that may protect against mental and behavioral health problems among Latino youth.
The study consists of two stages. During the first stage, the existing intervention will be adapted from a group-based, in-person format to a self-guided online format. The digital program will preserve the intervention's core parenting components while making the content more accessible and reducing the time and logistical demands associated with attending in-person sessions. Latino parents and community stakeholders will participate in an iterative user-centered refinement process to evaluate the program's cultural relevance, usability, clarity, and technological accessibility. Feedback from successive focus groups will be used to revise and finalize the digital intervention and its accompanying online manual.
The digital intervention will address parental involvement, monitoring, positive reinforcement and skill encouragement, appropriate and consistent discipline, family communication, and family problem solving. It will also address experiences relevant to Latino families, including familismo, respeto, parent-youth differences in acculturation, family and gender roles, language barriers, discrimination, and structural barriers affecting families. Program content will include brief presentations, demonstrations and video-based role plays, interactive activities, summaries of key concepts, and opportunities for parents to practice parenting strategies at home. Parents will proceed through the program sequentially and will receive access to new content on a weekly basis. An online discussion forum, periodic program-related messages, progress tracking, and contact with the research team will be used to support engagement.
During the second stage, the refined intervention will be evaluated in a randomized pilot trial. Participating families will be randomly assigned to receive either the LYFE-III online parenting intervention or services as usual through the collaborating community organization. Families assigned to services as usual will retain access to the organization's customary resources but will not receive LYFE-III during the trial. They will be offered access to the intervention after completion of study activities.
Parents and youth will complete online assessments before the intervention, at the end of the approximately four-month intervention period, and three months after the intervention ends. The pilot is intended to evaluate the feasibility, acceptability, appropriateness, engagement, and initial promise of delivering the culturally adapted intervention online. It will also estimate intervention-related changes in parenting practices and youth mental and behavioral health and examine whether changes in parenting practices are associated with subsequent changes in youth outcomes. Findings will be used to refine the intervention and its implementation procedures and to inform a future, larger-scale effectiveness trial.
- Conditions
- Control Condition, Parent
- Being tested
- Parenting Intervention
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Parenting InterventionBehavioural
LYFE-III is a culturally adapted, self-guided online parenting intervention delivered to parents of Latino youth over approximately four months. Parents receive sequential access to one digital module per week. Modules address parental involvement, monitoring, positive reinforcement and skill encouragement, consistent discipline, family communication, problem solving, and culturally relevant experiences such as familismo, respeto, parent-youth differences in acculturation, discrimination, and structural barriers. Modules include brief presentations, video demonstrations and role plays, interactive activities, summaries, and home-practice exercises. Engagement supports include weekly program-related messages, progress tracking, periodic contact from the research team, and an online discussion forum where parents can discuss their practice experiences and receive feedback.
| Study group | Role | What they receive |
|---|---|---|
| Parenting | Experimental | Families assigned to this arm will receive the LYFE-III digital version of Nuestras Familias: Andando Entre Culturas. Parents will complete sequential, self-guided online modules addressing parental involvement, monitoring, positive reinforcement and skill encouragement, consistent discipline, family communication, problem solving, and culturally relevant experiences affecting Latino families. The program includes presentations, video demonstrations, interactive activities, home-practice exercises, weekly messages, progress tracking, and an online discussion forum. Families may also receive services ordinarily available through the collaborating community organization. Receives: Behavioral: Parenting Intervention |
| Control | No intervention | Families assigned to this arm will not receive the LYFE-III intervention during the trial. They may continue to access services ordinarily available through the collaborating community organization. Use of these services will be monitored during the study. Families in this arm will be offered access to the LYFE-III online parenting intervention after completing study activities. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Parent-Reported and Youth-Reported General Parenting Scale Mean Score From Baseline to Immediately Post-Intervention
The 9-item General Parenting Scale assesses parents' perceived ability to use effective parenting practices, including communication, problem solving, encouragement, limit setting, monitoring, positive involvement, consistent discipline, and implementation of consequences. Each item is scored from 1 to 5. The mean score ranges from 1 to 5, with higher scores indicating more effective parenting practices.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Mean Acceptability of Intervention Measure Score Immediately Post-Intervention
The 4-item Acceptability of Intervention Measure assesses the extent to which participants perceive LYFE-III as agreeable, appealing, and satisfactory. Items are scored from 1 (completely disagree) to 5 (completely agree), and responses are averaged. Mean scores range from 1 to 5, with higher scores indicating greater intervention acceptability. This outcome is assessed among participants assigned to the LYFE-III intervention.
Measured: Immediately after completion of the approximately 3-week intervention
Mean Intervention Appropriateness Measure Score Immediately Post-Intervention
The 4-item Intervention Appropriateness Measure assesses the perceived fit, relevance, suitability, and applicability of LYFE-III. Items are scored from 1 (completely disagree) to 5 (completely agree), and responses are averaged. Mean scores range from 1 to 5, with higher scores indicating greater perceived appropriateness. This outcome is assessed among participants assigned to the LYFE-III intervention.
Measured: Immediately after completion of the approximately 3-week intervention
Mean Feasibility of Intervention Measure Score Immediately Post-Intervention
The 4-item Feasibility of Intervention Measure assesses the extent to which participants perceive LYFE-III as implementable, possible, doable, and easy to use. Items are scored from 1 (completely disagree) to 5 (completely agree), and responses are averaged. Mean scores range from 1 to 5, with higher scores indicating greater perceived feasibility. This outcome is assessed among participants assigned to the LYFE-III intervention.
Measured: Immediately after completion of the approximately 3-week intervention
Secondary outcomes (20)
Change in Parent-Reported General Parenting Scale Mean Score From Baseline to 3-Month Follow-Up
The 9-item General Parenting Scale assesses parents' perceived ability to use effective parenting practices, including communication, problem solving, encouragement, limit setting, monitoring, positive involvement, consistent discipline, and implementation of consequences. Each item is scored from 1 to 5. The mean score ranges from 1 to 5, with higher scores indicating more effective parenting practices.
Measured: Baseline and 3 months after intervention completion
Change in Youth-Reported Depressive Symptoms From Baseline to Immediately Post-Intervention
Youth depressive symptoms are assessed with the 9-item Patient Health Questionnaire Modified for Teens. Each item is scored from 0 (not at all) to 3 (nearly every day) and summed. Total scores range from 0 to 27, with higher scores indicating greater depressive symptom severity.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Anxiety Symptoms From Baseline to Immediately Post-Intervention
Youth anxiety symptoms are assessed with the 7-item Generalized Anxiety Disorder scale. Each item is scored from 0 (not at all) to 3 (nearly every day) and summed. Total scores range from 0 to 21, with higher scores indicating greater anxiety symptom severity.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Anxiety Symptoms From Baseline to 3-Month Follow-Up
Youth anxiety symptoms are assessed with the 7-item Generalized Anxiety Disorder scale. Each item is scored from 0 (not at all) to 3 (nearly every day) and summed. Total scores range from 0 to 21, with higher scores indicating greater anxiety symptom severity.
Measured: Baseline and 3 months after intervention completion
Change in Youth-Reported Externalizing Problems From Baseline to Immediately Post-Intervention
Externalizing problems are assessed with the 10-item Youth Externalizing Problems Screener. Items assess behaviors such as anger, arguing, rule breaking, aggression, impulsivity, inattention, and failure to follow directions. Each item is scored from 1 (almost never) to 4 (almost always) and summed. Total scores range from 10 to 40, with higher scores indicating more frequent externalizing problems.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Externalizing Problems From Baseline to 3-Month Follow-Up
Externalizing problems are assessed with the 10-item Youth Externalizing Problems Screener. Items assess behaviors such as anger, arguing, rule breaking, aggression, impulsivity, inattention, and failure to follow directions. Each item is scored from 1 (almost never) to 4 (almost always) and summed. Total scores range from 10 to 40, with higher scores indicating more frequent externalizing problems.
Measured: Baseline and 3 months after intervention completion
Change in Parent-Reported Youth Anxiety and Depression From Baseline to Immediately Post-Intervention
Parent-reported youth anxiety and depressive symptoms are assessed with the 25-item Revised Child Anxiety and Depression Scale-Parent Version. Each item is scored from 0 (never) to 3 (always). The total raw score ranges from 0 to 75, with higher scores indicating greater combined anxiety and depressive symptom severity. Anxiety and depression subscale scores may also be calculated.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Change in Parent-Reported Youth Anxiety and Depression From Baseline to 3-Month Follow-Up
Parent-reported youth anxiety and depressive symptoms are assessed with the 25-item Revised Child Anxiety and Depression Scale-Parent Version. Each item is scored from 0 (never) to 3 (always). The total raw score ranges from 0 to 75, with higher scores indicating greater combined anxiety and depressive symptom severity. Anxiety and depression subscale scores may also be calculated.
Measured: Baseline and 3 months after intervention completion
Percentage of Participants Completing All Assigned LYFE-III Intervention Modules
Intervention completion is defined as completing all required LYFE-III online modules. The outcome is calculated as the number of participants assigned to LYFE-III who complete all required modules divided by the total number assigned to LYFE-III, multiplied by 100. Percentages range from 0% to 100%, with higher percentages indicating greater intervention completion.
Measured: From intervention initiation through completion of the approximately 3-week intervention
Percentage of Enrolled Families Completing the 3-Month Follow-Up Assessment
Retention is calculated as the number of enrolled families who complete the 3-month post-intervention assessment divided by the total number of enrolled families, multiplied by 100. Percentages range from 0% to 100%, with higher percentages indicating greater study retention.
Measured: From enrollment through 3 months after intervention completion
Change in the Percentage of Youth Reporting Any Substance Use From Baseline to Immediately Post-Intervention
Youth substance use is assessed with the Oregon Social Learning Center Youth Substance Use Questionnaire. Any substance use is defined as self-reported use of one or more assessed substances, including alcohol, tobacco, marijuana, or another drug, during the questionnaire's specified recall period. The outcome is the percentage of youth meeting this criterion. Percentages range from 0% to 100%, with higher percentages indicating more substance use.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Change in the Percentage of Youth Reporting Any Substance Use From Baseline to 3-Month Follow-Up
Youth substance use is assessed with the Oregon Social Learning Center Youth Substance Use Questionnaire. Any substance use is defined as self-reported use of one or more assessed substances, including alcohol, tobacco, marijuana, or another drug, during the questionnaire's specified recall period. The outcome is the percentage of youth meeting this criterion. Percentages range from 0% to 100%, with higher percentages indicating more substance use.
Measured: Baseline and 3 months after intervention completion
Change in Youth-Reported Likelihood of Future Substance Use From Baseline to Immediately Post-Intervention
The Oregon Social Learning Center Youth Substance Use Questionnaire assesses youths' perceived likelihood of using alcohol, tobacco, marijuana, or other drugs in the future. Item responses will be averaged to calculate a mean likelihood-of-use score. Higher scores indicate a greater perceived likelihood of future substance use.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Likelihood of Future Substance Use From Baseline to 3-Month Follow-Up
The Oregon Social Learning Center Youth Substance Use Questionnaire assesses youths' perceived likelihood of using alcohol, tobacco, marijuana, or other drugs in the future. Item responses will be averaged to calculate a mean likelihood-of-use score. Higher scores indicate a greater perceived likelihood of future substance use.
Measured: Baseline and 3 months after intervention completion
Change in Youth-Reported Substance-Use Refusal Intentions From Baseline to Immediately Post-Intervention
The Oregon Social Learning Center Youth Substance Use Questionnaire assesses youths' intentions to refuse opportunities to use alcohol, tobacco, marijuana, or other drugs. Item responses will be averaged to calculate a mean refusal-intention score. Higher scores indicate stronger intentions to refuse substance use.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Substance-Use Refusal Intentions From Baseline to 3-Month Follow-Up
The Oregon Social Learning Center Youth Substance Use Questionnaire assesses youths' intentions to refuse opportunities to use alcohol, tobacco, marijuana, or other drugs. Item responses will be averaged to calculate a mean refusal-intention score. Higher scores indicate stronger intentions to refuse substance use.
Measured: Baseline and 3 months after intervention completion
Change in Parent-Reported Youth CRAFFT Substance-Related Risk Score From Baseline to Immediately Post-Intervention
Substance-related risk is assessed using the parent-report version of the CRAFFT Screening Interview. The six CRAFFT items assess riding in a vehicle with an impaired driver, using substances to relax or fit in, using substances alone, forgetting events while using substances, concerns expressed by family or friends, and substance-related trouble. Each "yes" response receives 1 point. Total scores range from 0 to 6, with higher scores indicating greater substance-related risk.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Change in Parent-Reported Youth CRAFFT Substance-Related Risk Score From Baseline to 3-Month Follow-Up
Substance-related risk is assessed using the parent-report version of the CRAFFT Screening Interview. The six CRAFFT items assess riding in a vehicle with an impaired driver, using substances to relax or fit in, using substances alone, forgetting events while using substances, concerns expressed by family or friends, and substance-related trouble. Each "yes" response receives 1 point. Total scores range from 0 to 6, with higher scores indicating greater substance-related risk.
Measured: Baseline and 3 months after intervention completion
Change in the Percentage of Youth Reported to Currently Use Tobacco From Baseline to Immediately Post-Intervention
Current tobacco use is assessed using the Consumer Self-Report Tobacco Assessment. Current use is defined as reported current use of at least one assessed tobacco product, including cigarettes, electronic cigarettes or vaping products, pipes, cigars, or chewing tobacco. The outcome is the percentage of youth meeting this criterion. Percentages range from 0% to 100%, with higher percentages indicating more current tobacco use.
Measured: Baseline and immediately after completion of the approximately 3-week intervention
Change in the Percentage of Youth Reported to Currently Use Tobacco From Baseline to 3-Month Follow-Up
Current tobacco use is assessed using the Consumer Self-Report Tobacco Assessment. Current use is defined as reported current use of at least one assessed tobacco product, including cigarettes, electronic cigarettes or vaping products, pipes, cigars, or chewing tobacco. The outcome is the percentage of youth meeting this criterion. Percentages range from 0% to 100%, with higher percentages indicating more current tobacco use.
Measured: Baseline and 3 months after intervention completion
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Aug 2026
- Study startSep 2026 (estimated)
- Primary completion31 Jul 2027 (estimated)
- Study completion31 Jul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Control ConditionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Texas A&M University
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute of Mental Health (NIMH)
- Responsible party
- Principal investigator, Cory Cobb, Texas A&M University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07761052
- Sponsor's protocol ID
- STUDY2025-1134
- Other IDs
- 5R34MH134935
- Acronym
- (LYFE-III)
- Status last verified
- Aug 2026
- First submitted
- 7 Aug 2026
- Last updated
- 13 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: This NIMH-funded study will generate individual-participant research data, and NIH expects investigators to share scientific data according to their approved plan. "Yes" does not mean posting identifiable or unrestricted data publicly. You can share deidentified data through a controlled-access repository or approved request process, with safeguards for minors and sensitive information such as immigration status.
Study at a glance
From the registry record, last updated by the sponsor on 13 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Latino Youth and Family Empowerment Study - III (LYFE-III): Bringing to Scale a Culturally-Adapted and Evidence-Based Intervention for Latino Families
- ClinicalTrials.gov ID
- NCT07761052
- Acronym / sponsor ID
- (LYFE-III) / STUDY2025-1134
- Conditions
- Control Condition, Parent
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- Texas A&M UniversityUniversity, hospital or other
- Collaborators
- National Institute of Mental Health (NIMH)
- Study start
- Sep 2026 (estimated)
- Primary completion
- 31 Jul 2027 (estimated)
- Study completion
- 31 Jul 2027 (estimated)
- First posted
- 12 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objective of this study is to harness digital technology to bring to scale a culturally adapted and evidence-based parenting intervention for Latinos (Nuestras Familias: Andando Entre Culturas). The Latino Youth and Family Empowerment - III study (LYFE-III) proposed here will adapt, scale, and evaluate the efficacy of an online version of Nuestras Familias with Latino parents and youth in a randomized controlled trial (RCT). The specific aims are as follows:
Aim 1. To adapt the Nuestras Familias intervention to an online format that can be widely accessed by underserved Latino families. This process includes intervention refinement, enhancing efficiency, and manualization of intervention content
Aim 2. Conduct a small randomized controlled pilot trial to (a) test the online program's promise while evaluating changes in target mechanisms of action (i.e., parenting practices) and their subsequent effects on youth mental health outcomes; and (b) to evaluate the feasibility, appropriateness, and acceptability of the online version of the Nuestras Familias intervention.
Detailed description
The Latino Youth and Family Empowerment Study-III (LYFE-III) is designed to adapt and pilot test Nuestras Familias: Andando Entre Culturas, a culturally adapted, evidence-based parenting intervention for Latino families. Nuestras Familias integrates principles from parent management training, social learning theory, and ecodevelopmental theory. The program is intended to strengthen parenting practices that may protect against mental and behavioral health problems among Latino youth.
The study consists of two stages. During the first stage, the existing intervention will be adapted from a group-based, in-person format to a self-guided online format. The digital program will preserve the intervention's core parenting components while making the content more accessible and reducing the time and logistical demands associated with attending in-person sessions. Latino parents and community stakeholders will participate in an iterative user-centered refinement process to evaluate the program's cultural relevance, usability, clarity, and technological accessibility. Feedback from successive focus groups will be used to revise and finalize the digital intervention and its accompanying online manual.
The digital intervention will address parental involvement, monitoring, positive reinforcement and skill encouragement, appropriate and consistent discipline, family communication, and family problem solving. It will also address experiences relevant to Latino families, including familismo, respeto, parent-youth differences in acculturation, family and gender roles, language barriers, discrimination, and structural barriers affecting families. Program content will include brief presentations, demonstrations and video-based role plays, interactive activities, summaries of key concepts, and opportunities for parents to practice parenting strategies at home. Parents will proceed through the program sequentially and will receive access to new content on a weekly basis. An online discussion forum, periodic program-related messages, progress tracking, and contact with the research team will be used to support engagement.
During the second stage, the refined intervention will be evaluated in a randomized pilot trial. Participating families will be randomly assigned to receive either the LYFE-III online parenting intervention or services as usual through the collaborating community organization. Families assigned to services as usual will retain access to the organization's customary resources but will not receive LYFE-III during the trial. They will be offered access to the intervention after completion of study activities.
Parents and youth will complete online assessments before the intervention, at the end of the approximately four-month intervention period, and three months after the intervention ends. The pilot is intended to evaluate the feasibility, acceptability, appropriateness, engagement, and initial promise of delivering the culturally adapted intervention online. It will also estimate intervention-related changes in parenting practices and youth mental and behavioral health and examine whether changes in parenting practices are associated with subsequent changes in youth outcomes. Findings will be used to refine the intervention and its implementation procedures and to inform a future, larger-scale effectiveness trial.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Parenting | Experimental | Behavioral: Parenting InterventionFamilies assigned to this arm will receive the LYFE-III digital version of Nuestras Familias: Andando Entre Culturas. Parents will complete sequential, self-guided online modules addressing parental involvement, monitoring, positive reinforcement and skill encouragement, consistent discipline, family communication, problem solving, and culturally relevant experiences affecting Latino families. The program includes presentations, video demonstrations, interactive activities, home-practice exercises, weekly messages, progress tracking, and an online discussion forum. Families may also receive services ordinarily available through the collaborating community organization. |
| Control | No intervention | –Families assigned to this arm will not receive the LYFE-III intervention during the trial. They may continue to access services ordinarily available through the collaborating community organization. Use of these services will be monitored during the study. Families in this arm will be offered access to the LYFE-III online parenting intervention after completing study activities. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- The family identifies as Latino or Hispanic.
- The family includes a child in the sixth or seventh grade.
- The child is newly enrolled in or has recently begun receiving services through Breakthrough Central Texas.
- At least one parent or primary caregiver speaks Spanish.
- A parent or primary caregiver and the participating child are willing to complete study assessments.
Key exclusion criteria (4 listed)
- The parent or primary caregiver is currently participating in another parenting education or parent-training program.
- A participating parent or child has an active, severe mental health condition, such as schizophrenia or another psychotic disorder, that would make participation in a preventive parenting program inappropriate.
- A participating parent or child has mental health or substance-use needs that, after review by a study psychologist, require a higher level of care than the LYFE-III prevention program provides.
- The parent or child is unable or unwilling to complete the study procedures or participate in the assigned study condition.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Parenting InterventionLYFE-III is a culturally adapted, self-guided online parenting intervention delivered to parents of Latino youth over approximately four months. Parents receive sequential access to one digital module per week. Modules address parental involvement, monitoring, positive reinforcement and skill encouragement, consistent discipline, family communication, problem solving, and culturally relevant experiences such as familismo, respeto, parent-youth differences in acculturation, discrimination, and structural barriers. Modules include brief presentations, video demonstrations and role plays, interactive activities, summaries, and home-practice exercises. Engagement supports include weekly program-related messages, progress tracking, periodic contact from the research team, and an online discussion forum where parents can discuss their practice experiences and receive feedback. | Behavioural | Parenting |
Primary outcome
Change in Parent-Reported and Youth-Reported General Parenting Scale Mean Score From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
The 9-item General Parenting Scale assesses parents' perceived ability to use effective parenting practices, including communication, problem solving, encouragement, limit setting, monitoring, positive involvement, consistent discipline, and implementation of consequences. Each item is scored from 1 to 5. The mean score ranges from 1 to 5, with higher scores indicating more effective parenting practices.
Mean Acceptability of Intervention Measure Score Immediately Post-Intervention
Time frame: Immediately after completion of the approximately 3-week intervention
The 4-item Acceptability of Intervention Measure assesses the extent to which participants perceive LYFE-III as agreeable, appealing, and satisfactory. Items are scored from 1 (completely disagree) to 5 (completely agree), and responses are averaged. Mean scores range from 1 to 5, with higher scores indicating greater intervention acceptability. This outcome is assessed among participants assigned to the LYFE-III intervention.
Mean Intervention Appropriateness Measure Score Immediately Post-Intervention
Time frame: Immediately after completion of the approximately 3-week intervention
The 4-item Intervention Appropriateness Measure assesses the perceived fit, relevance, suitability, and applicability of LYFE-III. Items are scored from 1 (completely disagree) to 5 (completely agree), and responses are averaged. Mean scores range from 1 to 5, with higher scores indicating greater perceived appropriateness. This outcome is assessed among participants assigned to the LYFE-III intervention.
Mean Feasibility of Intervention Measure Score Immediately Post-Intervention
Time frame: Immediately after completion of the approximately 3-week intervention
The 4-item Feasibility of Intervention Measure assesses the extent to which participants perceive LYFE-III as implementable, possible, doable, and easy to use. Items are scored from 1 (completely disagree) to 5 (completely agree), and responses are averaged. Mean scores range from 1 to 5, with higher scores indicating greater perceived feasibility. This outcome is assessed among participants assigned to the LYFE-III intervention.
20 secondary outcomes
Change in Parent-Reported General Parenting Scale Mean Score From Baseline to 3-Month Follow-Up
Time frame: Baseline and 3 months after intervention completion
Change in Youth-Reported Depressive Symptoms From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Anxiety Symptoms From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Anxiety Symptoms From Baseline to 3-Month Follow-Up
Time frame: Baseline and 3 months after intervention completion
Change in Youth-Reported Externalizing Problems From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Externalizing Problems From Baseline to 3-Month Follow-Up
Time frame: Baseline and 3 months after intervention completion
Change in Parent-Reported Youth Anxiety and Depression From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
Change in Parent-Reported Youth Anxiety and Depression From Baseline to 3-Month Follow-Up
Time frame: Baseline and 3 months after intervention completion
Percentage of Participants Completing All Assigned LYFE-III Intervention Modules
Time frame: From intervention initiation through completion of the approximately 3-week intervention
Percentage of Enrolled Families Completing the 3-Month Follow-Up Assessment
Time frame: From enrollment through 3 months after intervention completion
Change in the Percentage of Youth Reporting Any Substance Use From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
Change in the Percentage of Youth Reporting Any Substance Use From Baseline to 3-Month Follow-Up
Time frame: Baseline and 3 months after intervention completion
Change in Youth-Reported Likelihood of Future Substance Use From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Likelihood of Future Substance Use From Baseline to 3-Month Follow-Up
Time frame: Baseline and 3 months after intervention completion
Change in Youth-Reported Substance-Use Refusal Intentions From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
Change in Youth-Reported Substance-Use Refusal Intentions From Baseline to 3-Month Follow-Up
Time frame: Baseline and 3 months after intervention completion
Change in Parent-Reported Youth CRAFFT Substance-Related Risk Score From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
Change in Parent-Reported Youth CRAFFT Substance-Related Risk Score From Baseline to 3-Month Follow-Up
Time frame: Baseline and 3 months after intervention completion
Change in the Percentage of Youth Reported to Currently Use Tobacco From Baseline to Immediately Post-Intervention
Time frame: Baseline and immediately after completion of the approximately 3-week intervention
Change in the Percentage of Youth Reported to Currently Use Tobacco From Baseline to 3-Month Follow-Up
Time frame: Baseline and 3 months after intervention completion
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Aug 2026.
- Individual participant dataSharing planned: Yes. This NIMH-funded study will generate individual-participant research data, and NIH expects investigators to share scientific data according to their approved plan. "Yes" does not mean posting identifiable or unrestricted data publicly. You can share deidentified data through a controlled-access repository or approved request process, with safeguards for minors and sensitive information such as immigration status.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Parenting Intervention in people with Control Condition and Parent, run by Texas A&M University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 13 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Cory L Cobb, PhD (501-749-3382, cory.cobb@tamu.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Parent-Reported and Youth-Reported General Parenting Scale Mean Score From Baseline to Immediately Post-Intervention (time frame: Baseline and immediately after completion of the approximately 3-week intervention). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Aug 2026.