Post-Colonoscopy Nausea and VomitingNCT07761156
Effect of Chewing Exercises and Abdominal Massage
A study testing Abdominal massage and chewing egzersize in people with Post-Colonoscopy Nausea and Vomiting and Abdominal Pain, run by Sakarya University at 2 sites in Turkey (Türkiye).
Trial summary
This study is planned with a randomized controlled experimental design to determine the effects of chewing exercises during the pre-colonoscopy preparation process and abdominal massage applied after the procedure on abdominal pain and nausea symptoms. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Post-Colonoscopy Nausea and Vomiting, Abdominal Pain
- What is being tested?
- Abdominal massage and chewing egzersize
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 2 sitesTurkey (Türkiye)
- Study dates
- 1 Jun 2025to 30 Sep 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Aged 18 years and older
- Conscious oriented cooperative and open to communication
- Literate in Turkish
Who cannot join
- Under 18 years old -Malignancy
- Inadequate bowel cleaning
- Pregnancy or suspected pregnancy
- Mental disability or history of mental disorders
- Receiving psychiatric treatment or using anxiolytic medications
- History of prior bowel surgery
- Nausea and vomiting complaints due to other diseases such as migraine
Trial locations and contacts
2 sites in 1 country.
Turkey (Türkiye)2 sites
Sakarya University Education and Research Hospital
Sakarya, Serdivan, 54100
Sakarya University
Sakarya, Serdivan, 54100
About this study
Official title: The Effect of Chewing Exercises and Abdominal Massage on Abdominal Pain and Nausea Following Colonoscopy
This study is planned with a randomized controlled experimental design to determine the effects of chewing exercises during the pre-colonoscopy preparation process and abdominal massage applied after the procedure on abdominal pain and nausea symptoms.
Read the detailed description
The research population consists of patients applying to the Surgical Endoscopy Unit of a Training and Research Hospital for a colonoscopy. The sample will consist of individuals who agree to participate and meet the inclusion criteria. The study will be composed of two different groups: an experimental group and a control group. Group assignment will be determined by a randomized lottery method conducted by an independent observer.
Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. The educational information provided to the chewing exercise group will be based on the "Oral-Motor Exercises Brochure" published by the Ministry of Health. Participants will be asked to perform the specified exercises at least 2-3 times for a duration of 25-30 minutes the day before. Chewing is a recommended practice for generating saliva, relaxing gastric juice, and stimulating intestinal movements; thus, it is planned to alleviate the individual's post-colonoscopy gastrointestinal problems.
- Being tested
- Abdominal massage and chewing egzersize
- Keywords
- vomiting, colonoscopy, nausea, abdominal massage, gum chewing, abdominal pain
- Medical subject headings
- Vomiting, Abdominal Pain, Nausea
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Abdominal massage and chewing egzersizeOther
Arm Description: Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. Abdominal massage is a non-invasive, easy-to-apply method with no side effects, performed by nurses to reduce abdominal distension after colonoscopy. The researcher will apply it for 3-5 minutes when the patient is taken to the post-op recovery room after the procedure.
| Study group | Role | What they receive |
|---|---|---|
| Control | No intervention | No additional interventions were performed on the participants in this group following the colonoscopy. They received routine care. |
| Abdominal massage and chewing egzersize | Experimental | Arm Description: Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. Abdominal massage is a non-invasive, easy-to-apply method with no side effects, performed by nurses to reduce abdominal distension after colonoscopy. The researcher will apply it for 3-5 minutes when the patient is taken to the post-op recovery room after the procedure. Receives: Other: Abdominal massage and chewing egzersize |
What is being measured
The primary outcome is the main question the study is designed to answer.
Blood pressure measument
To measure blood pressure, the systolic and diastolic values are combined and expressed in mm/Hg.
Measured: 4 months
Oxygen saturation
Oxygen saturation will be expressed as a percentage.
Measured: 4 months
Pulse
The pulse rate will be measured and recorded as the number of heartbeats per minute.
Measured: 4 months
Pain assessment
Pain levels will be assessed on a scale from 0 to 10, where "0" indicates no pain and "10" indicates very severe pain.
Measured: 4 months
Presence of Nausea Before and After Colonoscopy (yes/no)
Nausea will be assessed based on participant self-report and recorded as a dichotomous outcome (present/absent) using the study data collection form. The presence or absence of nausea will be evaluated at three time points: before colonoscopy, after colonoscopy, and before discharge.
Measured: 4 months
Presence of Vomiting Before and After Colonoscopy (yes/no)
Vomiting will be assessed based on participant self-report and/or direct observation and recorded as a dichotomous outcome (present/absent) using the study data collection form. The presence or absence of vomiting will be evaluated at three time points: before colonoscopy, after colonoscopy, and before discharge.
Measured: 4 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Aug 2026
- Study start1 Jun 2025
- Primary completion1 Jun 2025
- Study completion30 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Post-Colonoscopy Nausea and VomitingStudies of the same condition, open and under way.
- More trials run by Sakarya UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. The educational information provided to the chewing exercise group will be based on the "Oral-Motor Exercises Brochure" published by the Ministry of Health. Participants will be asked to perform the specified exercises at least 2-3 times for a duration of 25-30 minutes the day before. Chewing is a recommended practice for generating saliva, relaxing gastric juice, and stimulating intestinal movements; thus, it is planned to alleviate the individual's post-colonoscopy gastrointestinal problems. Abdominal massage is a non-invasive, easy-to-apply method with no side effects, performed by nurses to reduce abdominal distension after colonoscopy. The researcher will apply it for 3-5 minutes when the patient is taken to the post-op recovery room after the procedure. Vital signs,
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Sakarya University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, özlem doğu, Sakarya University
- Investigators
- Özlem Doğu, PhD, Study director, Sakarya University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07761156
- Sponsor's protocol ID
- E-43012747-050.04-475033
- Status last verified
- Aug 2026
- First submitted
- 7 May 2026
- Last updated
- 12 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Once the study is completed, the data may be shared if requested by researchers.
Publications
Sinclair M. The use of abdominal massage to treat chronic constipation. J Bodyw Mov Ther. 2011 Oct;15(4):436-45. doi: 10.1016/j.jbmt.2010.07.007. Epub 2010 Aug 25.
PubMed 21943617Tanriverdi S, Parlar Kilic S. The Effect of Progressive Muscle Relaxation on Abdominal Pain and Distension in Colonoscopy Patients. J Perianesth Nurs. 2023 Apr;38(2):224-231. doi: 10.1016/j.jopan.2022.04.013. Epub 2022 Oct 31.
PubMed 36328945Mutlu S, Yilmaz E, Sahin ST. The effect of position change and abdominal massage on anxiety, pain and distension after colonoscopy: A randomized clinical trial. Explore (NY). 2024 Jan-Feb;20(1):89-94. doi: 10.1016/j.explore.2023.06.007. Epub 2023 Jun 20.
PubMed 37391282Öztürk, D., & Gürkan, A.; 2021; The effect of post colonoscopy abdominal massage on abdominal pain, distension, discomfort and patient satisfaction: A randomized controlled study protocol. International Journal of Clinical Trials; 8(4); 301-307.
Study at a glance
From the registry record, last updated by the sponsor on 12 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Chewing Exercises and Abdominal Massage on Abdominal Pain and Nausea Following Colonoscopy
- ClinicalTrials.gov ID
- NCT07761156
- Acronym / sponsor ID
- E-43012747-050.04-475033
- Keywords
- vomiting, colonoscopy, nausea, abdominal massage, gum chewing, abdominal pain
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Sakarya UniversityUniversity, hospital or other
- Study start
- 1 Jun 2025 (actual)
- Primary completion
- 1 Jun 2025 (actual)
- Study completion
- 30 Sep 2025 (actual)
- First posted
- 12 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is planned with a randomized controlled experimental design to determine the effects of chewing exercises during the pre-colonoscopy preparation process and abdominal massage applied after the procedure on abdominal pain and nausea symptoms.
Detailed description
The research population consists of patients applying to the Surgical Endoscopy Unit of a Training and Research Hospital for a colonoscopy. The sample will consist of individuals who agree to participate and meet the inclusion criteria. The study will be composed of two different groups: an experimental group and a control group. Group assignment will be determined by a randomized lottery method conducted by an independent observer.
Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. The educational information provided to the chewing exercise group will be based on the "Oral-Motor Exercises Brochure" published by the Ministry of Health. Participants will be asked to perform the specified exercises at least 2-3 times for a duration of 25-30 minutes the day before. Chewing is a recommended practice for generating saliva, relaxing gastric juice, and stimulating intestinal movements; thus, it is planned to alleviate the individual's post-colonoscopy gastrointestinal problems.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. The educational information provided to the chewing exercise group will be based on the "Oral-Motor Exercises Brochure" published by the Ministry of Health. Participants will be asked to perform the specified exercises at least 2-3 times for a duration of 25-30 minutes the day before. Chewing is a recommended practice for generating saliva, relaxing gastric juice, and stimulating intestinal movements; thus, it is planned to alleviate the individual's post-colonoscopy gastrointestinal problems. Abdominal massage is a non-invasive, easy-to-apply method with no side effects, performed by nurses to reduce abdominal distension after colonoscopy. The researcher will apply it for 3-5 minutes when the patient is taken to the post-op recovery room after the procedure. Vital signs,
| Arm | Type | Receives |
|---|---|---|
| Control | No intervention | –No additional interventions were performed on the participants in this group following the colonoscopy. They received routine care. |
| Abdominal massage and chewing egzersize | Experimental | Other: Abdominal massage and chewing egzersizeArm Description: Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. Abdominal massage is a non-invasive, easy-to-apply method with no side effects, performed by nurses to reduce abdominal distension after colonoscopy. The researcher will apply it for 3-5 minutes when the patient is taken to the post-op recovery room after the procedure. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Aged 18 years and older
- Conscious oriented cooperative and open to communication
- Literate in Turkish
Key exclusion criteria (7 listed)
- Under 18 years old -Malignancy
- Inadequate bowel cleaning
- Pregnancy or suspected pregnancy
- Mental disability or history of mental disorders
- Receiving psychiatric treatment or using anxiolytic medications
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Abdominal massage and chewing egzersizeArm Description: Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. Abdominal massage is a non-invasive, easy-to-apply method with no side effects, performed by nurses to reduce abdominal distension after colonoscopy. The researcher will apply it for 3-5 minutes when the patient is taken to the post-op recovery room after the procedure. | Other | Abdominal massage and chewing egzersize |
Primary outcome
Blood pressure measument
Time frame: 4 months
To measure blood pressure, the systolic and diastolic values are combined and expressed in mm/Hg.
Oxygen saturation
Time frame: 4 months
Oxygen saturation will be expressed as a percentage.
Pulse
Time frame: 4 months
The pulse rate will be measured and recorded as the number of heartbeats per minute.
Pain assessment
Time frame: 4 months
Pain levels will be assessed on a scale from 0 to 10, where "0" indicates no pain and "10" indicates very severe pain.
Presence of Nausea Before and After Colonoscopy (yes/no)
Time frame: 4 months
Nausea will be assessed based on participant self-report and recorded as a dichotomous outcome (present/absent) using the study data collection form. The presence or absence of nausea will be evaluated at three time points: before colonoscopy, after colonoscopy, and before discharge.
Presence of Vomiting Before and After Colonoscopy (yes/no)
Time frame: 4 months
Vomiting will be assessed based on participant self-report and/or direct observation and recorded as a dichotomous outcome (present/absent) using the study data collection form. The presence or absence of vomiting will be evaluated at three time points: before colonoscopy, after colonoscopy, and before discharge.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Aug 2026.
- Results publication: PubMed 21943617Sinclair M. The use of abdominal massage to treat chronic constipation. J Bodyw Mov Ther. 2011 Oct;15(4):436-45. doi: 10.1016/j.jbmt.2010.07.007. Epub 2010 Aug 25.
- Results publication: PubMed 36328945Tanriverdi S, Parlar Kilic S. The Effect of Progressive Muscle Relaxation on Abdominal Pain and Distension in Colonoscopy Patients. J Perianesth Nurs. 2023 Apr;38(2):224-231. doi: 10.1016/j.jopan.2022.04.013. Epub 2022 Oct 31.
- Results publication: PubMed 37391282Mutlu S, Yilmaz E, Sahin ST. The effect of position change and abdominal massage on anxiety, pain and distension after colonoscopy: A randomized clinical trial. Explore (NY). 2024 Jan-Feb;20(1):89-94. doi: 10.1016/j.explore.2023.06.007. Epub 2023 Jun 20.
- Results publicationÖztürk, D., & Gürkan, A.; 2021; The effect of post colonoscopy abdominal massage on abdominal pain, distension, discomfort and patient satisfaction: A randomized controlled study protocol. International Journal of Clinical Trials; 8(4); 301-307.
- Individual participant dataSharing planned: No. Once the study is completed, the data may be shared if requested by researchers.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Özlem Doğu, PhD study director
Sakarya University
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Abdominal massage and chewing egzersize in people with Post-Colonoscopy Nausea and Vomiting and Abdominal Pain, run by Sakarya University at 2 sites in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Blood pressure measument (time frame: 4 months). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07761156, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Aug 2026.