Cognitive ImpairmentNCT07764250
Comparative Evaluation of Immediate vs Progressive Standing Dual Task Training in Elderly With Mild and Moderate Cognitive Impairment
A study testing Immediate standing dual task training and progressive standing dual task training in people with Cognitive Impairment and Cognitive Impairment, Mild, run by Shifa Tameer-e-Millat University at 1 site in Pakistan.
Trial summary
older adults with mild and moderate cognitive impairment. compare immediate vs progressive standing dual-task training. assess balance, cognition, executive function, mobility, and quality of life. Read more about this study
- Who is it for?
- Ages 55 years and older
- Conditions the study is for
- Cognitive Impairment, Cognitive Impairment, Mild, Moderate Cognitive Impairment
- What is being tested?
- Immediate standing dual task training and progressive standing dual task training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 96 participants
- Where
- 1 sitePakistan
- Study dates
- 25 Jun 2026to 30 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 55 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age ≥55 years
- Mild or moderate cognitive impairment
- MoCA 10-25
- MMSE 10-23
- Able to participate
- Provides informed consent
Who cannot join
- Severe cognitive impairment
- Severe sensory or musculoskeletal impairments
- Unstable medical conditions
- Participation in another intervention study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Pakistan institute of medical sciences
Islamabad, Capital
Dr. Mansoor Iqbal, MBBS, FCPS Neurology, +923335547069, drmansooriqbalch@gmail.com
Erica Arthur, DPT
About this study
Official title: Immediate Versus Progressive-Standing Dual-Task Training: A Comparative Evaluation in Elderly With Mild and Moderate Cognitive Impairment
older adults with mild and moderate cognitive impairment. compare immediate vs progressive standing dual-task training. assess balance, cognition, executive function, mobility, and quality of life.
- Being tested
- Immediate standing dual task training, progressive standing dual task training
- Keywords
- CI, MCI, DTT, ISDTT, PSDDT
- Medical subject headings
- Cognitive Dysfunction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Immediate standing dual task trainingOther
Motor-cognitive dual-task training is a rehabilitation intervention delivered by a physiotherapist over 8 weeks, with three sessions per week, each lasting 45 minutes. Every session consists of a 5-minute warm-up, 30-35 minutes of dual-task training, and a 5-minute cool-down.
It simultaneously combines motor and cognitive tasks. Motor components include marching in place, finger tapping, hand transfer activities, side stepping, weight shifting, heel raises, heel-toe stepping, and balance challenges. Cognitive components include naming animals or fruits, counting forward, and months, serial subtraction by threes, backward digit span, alternate naming, and word recall.
Participants allocated to the Immediate Standing intervention perform all dual-task activities in standing from the first treatment session.
progressive standing dual task trainingOther
Motor-cognitive dual-task training is a rehabilitation intervention delivered by a physiotherapist over 8 weeks, with three sessions per week, each lasting 45 minutes. Every session consists of a 5-minute warm-up, 30-35 minutes of dual-task training, and a 5-minute cool-down.
It simultaneously combines motor and cognitive tasks. Motor components include marching in place, finger tapping, hand transfer activities, side stepping, weight shifting, heel raises, heel-toe stepping, and balance challenges. Cognitive components include naming animals or fruits, counting forward, and months, serial subtraction by threes, backward digit span, alternate naming, and word recall.
Participants allocated to the Progressive Standing intervention initially perform dual-task activities sitting and progressively transition to standing during the intervention period.
| Study group | Role | What they receive |
|---|---|---|
| Immediate Standing Dual-Task Training (Mild Cognitive Impairment) | Experimental | Not described Receives: Other: Immediate standing dual task training |
| Progressive Standing Dual-Task Training (Mild Cognitive Impairment) | Experimental | Not described Receives: Other: progressive standing dual task training |
| Immediate Standing Dual-Task Training (Moderate Cognitive Impairment) | Experimental | Not described Receives: Other: Immediate standing dual task training |
| Progressive Standing Dual-Task Training (Moderate Cognitive Impairment) | Experimental | Not described Receives: Other: progressive standing dual task training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mini-Mental State Examination
The Mini-Mental State Examination (MMSE) is a 30-point measure of global cognitive function. Scores range from 0 to 30, with higher scores indicating better cognitive function
Measured: Baseline and Week 8
Berg Balance Scale
The Berg Balance Scale (BBS) is a 14-item clinical measure of static and dynamic balance. Total scores range from 0 to 56, with higher scores indicating better balance performance.
Measured: Baseline and Week 8
Timed Up and Go
The Timed Up and Go Test measures functional mobility. The outcome is the time (seconds) required to stand from a chair, walk 3 meters, turn, return, and sit. Lower completion times indicate better mobility.
Measured: Baseline and Week 8
Trail Making Test
The Trail Making Test Part assesses executive function and cognitive flexibility. The outcome is the time (seconds) required to complete the test. Lower completion times indicate better executive function.
Measured: Baseline and Week 8
Secondary outcomes (1)
Quality of Life in Alzhiemer's Disease Scale
The Quality of Life in Alzheimer's Disease (QoL-AD) questionnaire consists of 13 items, with total scores ranging from 13 to 52. Higher scores indicate better quality of life.
Measured: Baseline and Week 8
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Aug 2026
- Study start25 Jun 2026
- Primary completion25 Aug 2026 (estimated)
- Study completion30 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cognitive ImpairmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomized Control Trial (RCT)
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 96 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Shifa Tameer-e-Millat University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fouzia Batool, Shifa Tameer-e-Millat University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07764250
- Sponsor's protocol ID
- 099-26
- Status last verified
- Aug 2026
- First submitted
- 9 Aug 2026
- Last updated
- 1 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 1 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Immediate Versus Progressive-Standing Dual-Task Training: A Comparative Evaluation in Elderly With Mild and Moderate Cognitive Impairment
- ClinicalTrials.gov ID
- NCT07764250
- Acronym / sponsor ID
- 099-26
- Keywords
- CI, MCI, DTT, ISDTT, PSDDT
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 96 participants (estimated)
- Lead sponsor
- Shifa Tameer-e-Millat UniversityUniversity, hospital or other
- Study start
- 25 Jun 2026 (actual)
- Primary completion
- 25 Aug 2026 (estimated)
- Study completion
- 30 Aug 2026 (estimated)
- First posted
- 13 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
older adults with mild and moderate cognitive impairment. compare immediate vs progressive standing dual-task training. assess balance, cognition, executive function, mobility, and quality of life.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 4
- Model description
- Randomized Control Trial (RCT)
| Arm | Type | Receives |
|---|---|---|
| Immediate Standing Dual-Task Training (Mild Cognitive Impairment) | Experimental | Other: Immediate standing dual task training |
| Progressive Standing Dual-Task Training (Mild Cognitive Impairment) | Experimental | Other: progressive standing dual task training |
| Immediate Standing Dual-Task Training (Moderate Cognitive Impairment) | Experimental | Other: Immediate standing dual task training |
| Progressive Standing Dual-Task Training (Moderate Cognitive Impairment) | Experimental | Other: progressive standing dual task training |
Who may qualify
- Ages
- 55 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Age ≥55 years
- Mild or moderate cognitive impairment
- MoCA 10-25
- MMSE 10-23
- Able to participate
Key exclusion criteria (4 listed)
- Severe cognitive impairment
- Severe sensory or musculoskeletal impairments
- Unstable medical conditions
- Participation in another intervention study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Immediate standing dual task trainingMotor-cognitive dual-task training is a rehabilitation intervention delivered by a physiotherapist over 8 weeks, with three sessions per week, each lasting 45 minutes. Every session consists of a 5-minute warm-up, 30-35 minutes of dual-task training, and a 5-minute cool-down. It simultaneously combines motor and cognitive tasks. Motor components include marching in place, finger tapping, hand transfer activities, side stepping, weight shifting, heel raises, heel-toe stepping, and balance challenges. Cognitive components include naming animals or fruits, counting forward, and months, serial subtraction by threes, backward digit span, alternate naming, and word recall. Participants allocated to the Immediate Standing intervention perform all dual-task activities in standing from the first treatment session. | Other | Immediate Standing Dual-Task Training (Mild Cognitive Impairment), Immediate Standing Dual-Task Training (Moderate Cognitive Impairment) |
| progressive standing dual task trainingMotor-cognitive dual-task training is a rehabilitation intervention delivered by a physiotherapist over 8 weeks, with three sessions per week, each lasting 45 minutes. Every session consists of a 5-minute warm-up, 30-35 minutes of dual-task training, and a 5-minute cool-down. It simultaneously combines motor and cognitive tasks. Motor components include marching in place, finger tapping, hand transfer activities, side stepping, weight shifting, heel raises, heel-toe stepping, and balance challenges. Cognitive components include naming animals or fruits, counting forward, and months, serial subtraction by threes, backward digit span, alternate naming, and word recall. Participants allocated to the Progressive Standing intervention initially perform dual-task activities sitting and progressively transition to standing during the intervention period. | Other | Progressive Standing Dual-Task Training (Mild Cognitive Impairment), Progressive Standing Dual-Task Training (Moderate Cognitive Impairment) |
Primary outcome
Mini-Mental State Examination
Time frame: Baseline and Week 8
The Mini-Mental State Examination (MMSE) is a 30-point measure of global cognitive function. Scores range from 0 to 30, with higher scores indicating better cognitive function
Berg Balance Scale
Time frame: Baseline and Week 8
The Berg Balance Scale (BBS) is a 14-item clinical measure of static and dynamic balance. Total scores range from 0 to 56, with higher scores indicating better balance performance.
Timed Up and Go
Time frame: Baseline and Week 8
The Timed Up and Go Test measures functional mobility. The outcome is the time (seconds) required to stand from a chair, walk 3 meters, turn, return, and sit. Lower completion times indicate better mobility.
Trail Making Test
Time frame: Baseline and Week 8
The Trail Making Test Part assesses executive function and cognitive flexibility. The outcome is the time (seconds) required to complete the test. Lower completion times indicate better executive function.
1 secondary outcome
Quality of Life in Alzhiemer's Disease Scale
Time frame: Baseline and Week 8
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Immediate standing dual task training and progressive standing dual task training in people with Cognitive Impairment and Cognitive Impairment, Mild, run by Shifa Tameer-e-Millat University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 1 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mini-Mental State Examination (time frame: Baseline and Week 8). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Sep 2026.