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Motor Control RetrainingMCR VS CKCNCT07766083

Motor Control Retraining vs Close Kinetic Chain Exercises for Pain, Function and Vastus Medialis Oblique Strength in Patients With Patellofemoral Pain Syndrome

A study testing Close Kinetic Chain Exercises in people with Motor Control Retraining and Close Kinetic Chain Exercises, run by University of Faisalabad at 1 site in Pakistan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This study compares two treatments - motor control retraining and close kinetic chain exercises - to improves the pain, VMO strength, knee function. Fifty participants out of which 4 dropped out; will be randomly assigned to receive either motor control retraining or close kinetic chain exercises training for 45… Read more about this study

Who is it for?
Ages 18 to 40 years
What is being tested?
Close Kinetic Chain Exercises
Could I receive a placebo?
No, everyone receives an active treatment
How many people
50 participants
Where
1 sitePakistan
Study dates
24 Apr 2026to 9 Aug 2026
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 40 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • Age between 18 and 40 years old.
  • Both genders male \& female.
  • Clinically diagnosed PFPS patients.
  • Anterior knee pain >3 on VAS for > 2 weeks.
  • Retropatellar pain during at least 3 of the following activities, i.e., jumping, kneeling, ascending \& descending stairs, squatting, running, prolonged sitting.
  • BMI range from 18.5 - 24.9 kg/m² .
Show all 11Show fewer
  • Not receiving previously knee physiotherapy.
  • Insidious onset of symptoms unrelated to trauma.
  • Patellar compression test positive.
  • Clarke's test positive.
  • Snapps questionnaire score 6 or greater.

Who cannot join

  • Age > 40 years old.
  • Knee joint effusion .
  • BMI < 18 \& > 29 kg/m².
  • Any other significant injury that affect lower limb .
  • Any history of previous knee surgery.
  • Having referred pain from the lumbar, hip, ankle, feet, and SIJ .
Show all 15Show fewer
  • Any history of knee pathology, including OA, meniscus injury, ligament injury, tendon injury, cartilage injury, iliotibial band involvement, intra articular pathology, patellar instability, osgood-schlatter syndrome, pes anserine pain, RA of knee .
  • Any history of neurological condition .
  • Pregnant females .
  • Any condition affected muscle strength, i.e., gout, DM, RA .
  • History of head injury, vestibular disorder within 6 months.
  • Any history of patellar dislocation or subluxation .
  • Signs and symptoms < 1 month.
  • Use of corticosteroids, anti-inflammatory \& intra-articular injections.
  • Heart condition that precluded performing exercises.

Trial locations and contacts

1 site in 1 country.

Pakistan1 site

  • Department of Rehabilitation Sciences, The University of Faisalabad

    Faisalabad, Punjab Province, 38000

Other trials in Pakistan

About this study

Official title: Comparative Effects of Motor Control Retraining and Close Kinetic Chain Exercises on Pain, Function and Vastus Medialis Oblique Strength in Patients With Patellofemoral Pain Syndrome

This study compares two treatments - motor control retraining and close kinetic chain exercises - to improves the pain, VMO strength, knee function. Fifty participants out of which 4 dropped out; will be randomly assigned to receive either motor control retraining or close kinetic chain exercises training for 45 minutes per session, three times per week, for six weeks. Pain intensity will be measured using the visual analogue scale. Knee function will be measured using Kujala anterior knee pain scale. Vastus medialis oblique strength will be measured using digital dynamometer. Dynamic knee valgus will be measured using Kinovea-2D video analysis. Q-angle will be measured using manual goniometer. Patellar maltracking will be measured using combined assessment of dynamic knee valgus and q-angle. This study aims to determine which treatment produces greater improvements, which may help physiotherapists choose more effective treatments for patient with patellofemoral pain syndrome in Pakistan.

Read the detailed description

Background: Patellofemoral pain syndrome, another name for anterior knee discomfort, is brought on by a combination of abnormal patellar tracking, changed biomechanics, and muscle imbalances that put more strain on the patellofemoral joint during activities including jogging, squatting, and stair climbing. In general practice, patellofemoral pain contributes to 11-17% of all knee pain syndromes. Motor control retraining is a rehabilitation treatment that focus on activation and timing of VMO, controlled functional movements, dynamic integration while close kinetic chain exercises is also a rehabilitation treatment that focus on low and moderate load close kinetic chain exercises with advanced functional exercises that focuses on VMO activation.

Being tested
Motor Control Retraining, Close Kinetic Chain Exercises
Keywords
Patellofemoral pain syndrome, Motor control retraining, Close kinetic chain exercises, Vastus medialis oblique, knee function, dynamic knee valgus
Medical subject headings
Patellofemoral Pain Syndrome

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Motor Control RetrainingOther

    Also called Motor control retraining exercise

    What: A supervised exercise program consisting of motor control retraining exercises designed to improve neuromuscular control, movement coordination, muscle activation, and postural stability. The exercises are performed under supervision three times per week for 6 weeks.

    When: 45 minutes per session, 3 sessions per week, for 6 consecutive weeks (total 18 sessions). How much: Each exercise performed for 10-15 seconds, with 3×5 reps, with rest periods as needed. By whom: Licensed physiotherapist trained in motor control retraining exercises. Where: Outpatient rehabilitation department of MTH (Madinah Teaching Hospital), Faisalabad; Pro Health Rehab \& Medical Centre, Faisalabad; United Hospital, Faisalabad.

  • Close Kinetic Chain ExercisesOther

    What: A supervised exercise program consisting of closed kinetic chain exercises designed to improve muscle strength, joint stability, neuromuscular control, and functional movement. The exercises are performed under supervision three times per week for 6 weeks.

    When: 45 minutes per session, 3 sessions per week, for 6 consecutive weeks (total 18 sessions). How much: Each exercise performed for 10-15 seconds, with 3×5 reps, with rest periods as needed. By whom: Licensed physiotherapist trained in close kinetic chain exercises. Where: Outpatient rehabilitation department of MTH (Madinah Teaching Hospital), Faisalabad; Pro Health Rehab \& Medical Centre, Faisalabad; United Hospital, Faisalabad.

Study groups in NCT07766083
Study groupRoleWhat they receive
Motor control retraining GroupExperimentalMotor control retraining will receive baseline treatment including static stretching of the hamstrings, iliotibial band, and calf muscle of the affected limb with 2 sets of 5 repetitions with a 5-second hold, followed by a Motor Control Retraining program focused on vastus medialis oblique isometric activation with visual feedback, quadriceps setting with VMO emphasis; seated short arc quads (0-30°) with manual cueing will performed at low intensity by participant for 1st and 2nd week. In phase 2 (controlled functional recruitment), mini-squats with verbal and tactile cueing to optimize VMO activation and lateral step-downs focusing on medial quadriceps control will performed withlow to moderate intensity by participant for 3rd and 4th week. In phase 3 (dynamic integration), single leg squat to 45° with feedback and functional tasks (stair scent/descent drills,controlled landing from 20 cm) will performed with moderate intensity by participant for 5th and 6th week.
Receives: Other: Motor Control Retraining
Close kinetic chain exercises GroupActive comparatorClose kinetic chain exercises will receive baseline treatment including static stretching of the hamstrings, iliotibial band, and calf muscle of the affected limb with 2 sets of 5 repetitions with a 5-second hold, followed by a Closed Kinetic Chain Exercise program including wall squats / mini-squats (0-30°) and terminal knee extension in mini-CKC (band resistance) will performed with low intensity by participant for 1st and 2nd week. In phase 2 (moderate load CKC), step-ups / step-downs (20 cm) and forward lunges (partial range) will performed with low to moderate intensity by participant for 3rd and 4th week. In phase 3 (advanced functional), single-leg squat (to 45°) and lateral lunges will performed with moderate intensity by participant for 5th and 6th week. The dosage of these exercises will 3 sets × 10 reps with 5 sec hold for 3 days /week for 6 weeks. The mode of administration was one-on-one.
Receives: Other: Close Kinetic Chain Exercises

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Pain Intensity

    The visual analogue scale (VAS), a robust and trustworthy self-reported measure of pain, was used to gauge pain severity. The VAS is a 10-cm straight line, with "no pain" at one end and "worst pain" at the other. The participants were asked to mark the location that most accurately reflected the level of pain they were experiencing at the time. Greater pain severity was reflected by higher scores. With reported validity coefficients ranging from r = 0.71 to 0.78 and great reliability (ICC = 0.97), the visual analogue scale is a reliable and valid tool for measuring pain intensity.

    Measured: Baseline (week 0, before first intervention session), mid-intervention; week 3, after 9th session, and post-intervention (week 6, within 48 hours after the final intervention session)

  2. Knee Function

    The kujala anterior knee pain scale (AKPS), a disease-specific questionnaire intended to assess symptoms and functional limitations associated with patellofemoral diseases, was used to measure knee function. Thirteen elements make up the scale, which evaluates pain, limping, swelling, stair climbing, squatting, jogging, jumping, extended sitting, and other functional tasks. Better knee function and less complaints are indicated by higher scores, which range from 0 to 100. A highly valid and reliable tool for assessing symptoms and functional limitations related to patellofemoral diseases is the Kujala Anterior Knee Pain Scale (AKPS). It exhibits great test-retest reliability, greater internal consistency (Cronbach's α = 0.83-0.91), and strong validity (r = 0.90-0.92).

    Measured: Baseline (week 0, before first intervention session), mid-intervention; week 3, after 9th session, and post-intervention (week 6, within 48 hours after the final intervention session)

  3. Vastus Medialis Oblique Strength

    A hand-held dynamometer (Lafayette Instrument Model 01160) was used to evaluate the strength of the vastus medialis oblique (VMO) muscle. In standardized testing positions, participants executed maximal voluntary isometric contractions, and the force produced was measured. Stronger quadriceps and VMO muscles were indicated by higher values. A Hand-Held Dynamometer (HHD; Lafayette 01160) was used to measure the strength of the Vastus Medialis Oblique (VMO) muscle at 60° knee flexion. The HHD's application for assessing lower-extremity muscle strength is supported by its moderate to strong validity (r = 0.62-0.91) and acceptable to excellent reliability (ICC ≥ 0.70).

    Measured: Baseline (week 0, before first intervention session), mid-intervention; week 3, after 9th session, and post-intervention (week 6, within 48 hours after the final intervention session)

Secondary outcomes (3)

  1. Dynamic Knee Valgus

    Kinovea 2D motion analysis software was used to measure dynamic knee valgus. Functional exercises like squatting, step-down chores, and single-leg movements were captured on video. Frontal-plane knee motion was measured and lower-limb alignment was examined using Kinovea software. Greater dynamic knee valgus was indicated by increased medial displacement of the knee during movement.

    For evaluating lower-extremity kinematics and dynamic movement patterns, such as Dynamic Knee Valgus, Kinovea 2D Motion Analysis Software has shown great concurrent validity and excellent reliability (ICC = 0.916)

    Measured: Baseline (week 0, before first intervention session) and post-intervention (week 6, within 48 hours after the final intervention session)

  2. Q-Angle

    The q-angle was measured using a universal manual goniometer. An imagined line was drawn from the ASIS to the patella center, and another line was drawn from the patella center to the tibial tuberosity in order to calculate the angle. Increased lateral patellar tracking and modified patellofemoral biomechanics are linked to higher Q-angle values. A viable and trustworthy tool for determining the Q-angle is the manual goniometer. Good validity, greater intra-rater reliability (ICC = 0.88), and moderate to high inter-rater reliability (ICC = 0.77-0.85) have all been shown.

    Measured: Baseline (week 0, before first intervention session) and post-intervention (week 6, within 48 hours after the final intervention session)

  3. Patellar Maltracking

    Dynamic knee valgus analysis and q-angle measurements were coupled to evaluate functional patellar maltracking. Instead of static anatomical malalignment, a normal Q-angle in the presence of severe dynamic knee valgus may suggest functional patellar maltracking because of changed lower-extremity movement patterns. This evaluation helped detect aberrant movement patterns causing anterior knee pain and shed light on the mechanics of the patellofemoral joint during functional activities A useful measure of lower-limb alignment during practical activities, functional patellar maltracking assessment using the combination of Normal Q-angle and High Frontal Plane Projection Angle (FPPA) has demonstrated acceptable to strong validity (r ≈ 0.64-0.78) and excellent reliability (ICC ≈ 0.88-0.89).

    Measured: Baseline (week 0, before first intervention session) and post-intervention (week 6, within 48 hours after the final intervention session)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted14 Aug 2026
  2. Study start24 Apr 2026
  3. Primary completion10 Jul 2026
  4. Study completion9 Aug 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
50 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07766083
Sponsor's protocol ID
2024-MS-PT-017
Acronym
MCR VS CKC
Status last verified
Aug 2026
First submitted
10 Aug 2026
Last updated
14 Aug 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided

Publications

  • Alba-Martín P, Gallego-Izquierdo T, Plaza-Manzano G et al. (2015) Effectiveness of therapeutic physical exercise in the treatment of patellofemoral pain syndrome: A systematic review. Journal of Physical Therapy Science 27(7): 2387-2390. Almeida G, Silva A, França F et al. (2016) Q-angle in patellofemoral pain: Relationship with dynamic knee valgus, hip abductor torque, pain and function. Revista Brasileira De Ortopedia 51(2): 181-186. Alrshood A, El Alwani A, Amein NE et al. (2017) A systematic review of the effect of open and closed kinetic chain exercises on the vastus medialis oblique and vastus lateralis muscles of patients with patellofemoral pain syndrome. International Journal of Orthopaedics 3(1): 152-161. Arhos E, Lang C, Steger-May K et al. (2021) Task-specific movement training improves kinematics and pain during the Y-balance test and hip muscle strength in females with patellofemoral pain. Journal of International Society Arthroscopy Knee Surgery and Orthopaedic Sports Medicine 6(5): 277-282. Ayık B, Armağan O and Bakılan F (2025) Comparison of open and closed kinetic chain exercises on vastus medialis and vastus medialis oblique in patellofemoral pain syndrome: A randomized single-blinded, prospective study. Turkish Journal of Physical Medicine & Rehabilitation (2587-1250) 71(2): 216-225. Balci P, Tunay V, Baltaci G et al. (2009) The effects of two different closed kinetic chain exercises on muscle strength and proprioception in patients with patellofemoral pain syndrome. Acta Orthopaedica Et Traumatologica Turcica 43(5): 419-425. Baldon RDM, Serrão FV, Scattone SR et al. (2014) Effects of functional stabilization training on pain, function, and lower extremity biomechanics in women with patellofemoral pain: A randomized clinical trial. Journal of Orthopaedic & Sports Physical Therapy 44(4): 240-251. Begum MR and Hossain MA (2019) Validity and reliability of visual analogue scale (VAS) for pain measurement. Journal of Medical Case Reports and Review

  • Petersen W, Ellermann A, Gösele-Koppenburg A et al. (2014) Patellofemoral pain syndrome. Knee Surgery, Sports Traumatology, Arthroscopy 22(10): 2264-2274. Powers CM (2003) The influence of altered lower-extremity kinematics on patellofemoral joint dysfunction: A theoretical perspective. Journal of Orthopaedic & Sports Physical Therapy 33(11): 639-646. Scholtes SA and Salsich GB (2017) A dynamic valgus index that combines hip and knee angles: Assessment of utility in females with patellofemoral pain. International Journal of Sports Physical Therapy 12(3): 333. Scholtes SA and Salsich GB (2020) Consistency of dynamic knee valgus kinematics and pain across functional tasks in females with patellofemoral pain: A cross-sectional study. International Journal of Sports Physical Therapy 15(6): 985. Sheehan FT, Derasari A, Fine KM et al. (2010) Q-angle and j-sign: Indicative of maltracking subgroups in patellofemoral pain. Clinical Orthopaedics and Related Research® 468(1): 266-275. Skouras AZ, Kanellopoulos AK, Stasi S et al. (2022) Clinical significance of the static and dynamic q-angle. Cureus 14(5): e24911. Smith B, Selfe J, Thacker D et al. (2018) Incidence and prevalence of patellofemoral pain: A systematic review and meta-analysis. Plos One 13(1): e0190892.

  • Ismail M, Gamaleldein M, Hassa K et al. (2013) Closed kinetic chain exercises with or without additional hip strengthening exercises in management of patellofemoral pain syndrome: A randomized controlled trial. The European Journal of Physical and Rehabilitation Medicine 49(5): 687-698. Ittenbach RF, Huang G, Barber Foss KD et al. (2016) Reliability and validity of the anterior knee pain scale: Applications for use as an epidemiologic screener. Plos One 11(7): e0159204. Jamaludin NI, Sahabuddin FNA, Rasudin NS et al. (2022) The concurrent validity and reliability of single leg squat among physically active females with and without dynamic knee valgus. International Journal of Sports Physical Therapy 17(4): 574. Kim H (2025) Effects of selective training on the vastus medialis oblique in patients with patellofemoral pain syndrome. Physical Therapy Rehabilitation Science 14(1): 91-101. Llurda-Almuzara L, Pérez-Bellmunt A, Lopez-De-Celis C et al. (2020) Normative data and correlation between dynamic knee valgus and neuromuscular response among healthy active males: A cross-sectional study. Scientific Reports 10(1): 17206. Mentiplay BF, Perraton LG, Bower KJ et al. (2015) Assessment of lower limb muscle strength and power using hand-held and fixed dynamometry: A reliability and validity study. Plos One 10(10): e0140822. Minoonejad H, Rajabi R, Ebrahimi-Takamjani et al. (2012) Combined open and closed kinetic chain exercises for patellofemoral pain syndrome: A randomized controlled trial. World J Sport Sci 6(3): 278-85. Mozafaripour E, Seidi F, Minoonejad H et al. (2022) The effectiveness of the comprehensive corrective exercise program on kinematics and strength of lower extremities in males with dynamic knee valgus: A parallel-group randomized wait-list controlled trial. BioMed Central Musculoskeletal Disorders 23(1): 700.

  • Fehr GL, Cliquet Junior A, Cacho ÊWA et al. (2006) Effectiveness of the open and closed kinetic chain exercises in the treatment of the patellofemoral pain syndrome. Revista Brasileira De Medicina Do Esporte 12(2): 66-70. Fernández-González P, Koutsou A, Cuesta-Gomez A et al. (2020) Reliability of kinovea software and agreement with a three-dimensional motion system for gait analysis in healthy subjects. Sensors 20(11): 3154. Frings J, Dust T, Frosch K et al. (2020) Objective assessment of patellar maltracking with 3 T dynamic magnetic resonance imaging: Feasibility of a robust and reliable measuring technique. Scientific Reports 10(1): 16770. Fukuda TY, Rossetto FM, Magalhães E et al. (2010) Short-term effects of hip abductors and lateral rotators strengthening in females with patellofemoral pain syndrome: A randomized controlled clinical trial. Journal Of Orthopaedic & Sports Physical Therapy 40(11): 736-742. Harvie D, O'leary T, Kumar S et al. (2011) A systematic review of randomized controlled trials on exercise parameters in the treatment of patellofemoral pain: What works? Journal of Multidisciplinary Healthcare 4(2011): 383-392. Holden S, Boreham C, Doherty C et al. (2017) Two-dimensional knee valgus displacement as a predictor of patellofemoral pain in adolescent females. Scandinavian Journal of Medicine & Science in Sports 27(2): 188-194.

  • Bolgla L, Gibson H, Hannah D et al. (2023) Comparison of the frontal plane projection angle and the dynamic valgus index to identify movement dysfunction in females with patellofemoral pain. International Journal of Sports Physical Therapy 18(3): 619. Chamorro C, Armijo-Olivo S, De La Fuente C et al. (2017) Absolute reliability and concurrent validity of hand held dynamometry and isokinetic dynamometry in the hip, knee and ankle joint: A systematic review and meta-analysis. Open Medicine 12(1): 359-375. Chang W, Huang W and Lai P (2015) Muscle activation of vastus medialis oblique and vastus lateralis in sling-based exercises in patients with patellofemoral pain syndrome: A cross-over study. Evidence-Based Complementary and Alternative Medicine 2015(1): 740315. Crossley K, Callaghan M and Van Linschoten R (2016a) Patellofemoral pain. British Journal of Sports Medicine 50(4): 247-250. Crossley K, Van Middelkoop M, Callaghan M et al. (2016b) Patellofemoral pain consensus statement from the 4th international patellofemoral pain research retreat, manchester. Part 2: Recommended physical interventions (exercise, taping, bracing, foot orthoses and combined interventions). British Journal of Sports Medicine 50(14); 844-852. Darabseh M, Aburub A, Altaim T et al. (2024) Validity and reliability of an arabic version of the survey instrument for natural history, aetiology and prevalence of patellofemoral pain studies: A cross-sectional study. International Journal of Environmental Research and Public Health 21(6): 732. De Souza Júnior J, Rabelo P, Lemos T et al. (2024) Effects of two gait retraining programs on pain, function, and lower limb kinematics in runners with patellofemoral pain: A randomized controlled trial. Plos One 19(1): e0295645. Dolak KL, Silkman C, Mckeon JM et al. (2011) Hip strengthening prior to functional exercises reduces pain sooner than quadriceps strengthening in females with patellofemoral pain syndrome: A randomized clinical trial. Journal Of Orthop

  • Ayık B, Armağan O and Bakılan F (2025) Comparison of open and closed kinetic chain exercises on vastus medialis and vastus medialis oblique in patellofemoral pain syndrome: A randomized single-blinded, prospective study. Turkish Journal of Physical Medicine & Rehabilitation (2587-1250) 71(2): 216-225. Balci P, Tunay V, Baltaci G et al. (2009) The effects of two different closed kinetic chain exercises on muscle strength and proprioception in patients with patellofemoral pain syndrome. Acta Orthopaedica Et Traumatologica Turcica 43(5): 419-425. Baldon RDM, Serrão FV, Scattone SR et al. (2014) Effects of functional stabilization training on pain, function, and lower extremity biomechanics in women with patellofemoral pain: A randomized clinical trial. Journal of Orthopaedic & Sports Physical Therapy 44(4): 240-251. Begum MR and Hossain MA (2019) Validity and reliability of visual analogue scale (VAS) for pain measurement. Journal of Medical Case Reports and Reviews 2(11): 2589-8647.

  • Arhos EK, Lang CE, Steger-May K, Van Dillen LR, Yemm B, Salsich GB. Task-specific movement training improves kinematics and pain during the Y-balance test and hip muscle strength in females with patellofemoral pain. J ISAKOS. 2021 Sep;6(5):277-282. doi: 10.1136/jisakos-2020-000551. Epub 2021 May 17.

    PubMed 34001505

  • Alrshood A, El Alwani A, Amein NE et al. (2017) A systematic review of the effect of open and closed kinetic chain exercises on the vastus medialis oblique and vastus lateralis muscles of patients with patellofemoral pain syndrome. International Journal of Orthopaedics 3(1): 152-161.

  • Almeida GP, Silva AP, Franca FJ, Magalhaes MO, Burke TN, Marques AP. Q-angle in patellofemoral pain: relationship with dynamic knee valgus, hip abductor torque, pain and function. Rev Bras Ortop. 2016 Feb 9;51(2):181-6. doi: 10.1016/j.rboe.2016.01.010. eCollection 2016 Mar-Apr.

    PubMed 27069887

  • Alba-Martin P, Gallego-Izquierdo T, Plaza-Manzano G, Romero-Franco N, Nunez-Nagy S, Pecos-Martin D. Effectiveness of therapeutic physical exercise in the treatment of patellofemoral pain syndrome: a systematic review. J Phys Ther Sci. 2015 Jul;27(7):2387-90. doi: 10.1589/jpts.27.2387. Epub 2015 Jul 22.

    PubMed 26311988

Questions about this trial

What is this clinical trial studying?

A study testing Close Kinetic Chain Exercises in people with Motor Control Retraining and Close Kinetic Chain Exercises, run by University of Faisalabad at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 11 inclusion and 15 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 14 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Pain Intensity (time frame: Baseline (week 0, before first intervention session), mid-intervention; week 3, after 9th session, and post-intervention (week 6, within 48 hours after the final intervention session)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07766083, which also lists 10 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Aug 2026.

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