Knee Arthritis OsteoarthritisNCT07767812
Effects of Motivational Interviewing on Pain Self-Efficacy and Exercise Behavior in Individuals With Knee Osteoarthritis
A study testing Motivational Interviewing, Neuromuscular Exercise Program and Home Exercise Program in people with Knee Arthritis Osteoarthritis, run by Kutahya Health Sciences University at 1 site in Turkey (Türkiye).
Trial summary
This randomized controlled trial aims to investigate the effects of motivational interviewing added to a neuromuscular exercise and home exercise program on pain self-efficacy, exercise behavior, pain intensity, physical performance, and functional status in individuals with knee osteoarthritis. Read more about this study
- Who is it for?
- Ages 40 years and older
- Conditions the study is for
- Knee Arthritis Osteoarthritis
- What is being tested?
- Motivational Interviewing, Neuromuscular Exercise Program and Home Exercise Program
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 56 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Feb 2026to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosis of knee osteoarthritis according to American College of Rheumatology (ACR) criteria
- Kellgren-Lawrence radiographic grade ≥2
- Knee pain lasting longer than 3 months
Who cannot join
- History of joint arthroplasty
- Body mass index >40 kg/m²
- Neuromuscular or neurological diseases such as stroke, Parkinson's disease, or multiple sclerosis
- History of lower-extremity joint fracture
- Hip osteoarthritis
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
AFSÜ Health Application and Research Center, Department of Physical Therapy and Rehabilitation
Afyonkarahisar, Türkiye, 03100
Aynur EYVAZ, MD, 00902742651100, aynureyvaz@afsu.edu.tr
İbrahim YUKSEL, Msc.
About this study
Official title: Investigation of the Effects of Motivational Interviewing on Pain Self-Efficacy and Exercise Behavior in Individuals With Knee Osteoarthritis
This randomized controlled trial aims to investigate the effects of motivational interviewing added to a neuromuscular exercise and home exercise program on pain self-efficacy, exercise behavior, pain intensity, physical performance, and functional status in individuals with knee osteoarthritis. Sixty individuals diagnosed with knee osteoarthritis will be randomly allocated to either an intervention group or a control group. The intervention group will receive motivational interviewing in addition to neuromuscular exercise and a home exercise program, whereas the control group will receive neuromuscular exercise and the same home exercise program. Outcomes will be assessed at baseline, immediately after the intervention, and six weeks after the intervention.
- Conditions
- Knee Arthritis Osteoarthritis
- Being tested
- Motivational Interviewing, Neuromuscular Exercise Program, Home Exercise Program
- Keywords
- KNEE OSTEOARTHRITIS, MOTIVATIONAL INTERVIEWING, EXERCISE
- Medical subject headings
- Osteoarthritis, Knee, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Motivational InterviewingBehavioural
Motivational interviewing will be delivered individually in face-to-face sessions by a researcher trained and certified in motivational interviewing. Sessions will focus on identifying individual barriers and goals, strengthening motivation and commitment to exercise, supporting self-efficacy, and preventing relapse. The intervention will incorporate three stages: increasing exercise motivation, strengthening commitment to exercise, and relapse prevention.
Neuromuscular Exercise ProgramOther
Participants will perform neuromuscular exercise sessions five times per week for four weeks. Each 60-minute session will consist of approximately 10 minutes of warm-up, 40 minutes of exercise, and 10 minutes of cool-down. Exercises will include core stabilization and postural control, postural orientation, lower-extremity strengthening, functional exercises, and balance and proprioception exercises. Exercises will be progressed according to participant tolerance and functional performance.
Home Exercise ProgramOther
The home exercise program will include isometric strengthening exercises for the quadriceps and hip adductor muscles, straight leg raising, assisted hip and knee flexion, and active knee flexion exercises. Participants will perform the program five days per week, twice daily, for three weeks, with 10 repetitions of each exercise. The program will be explained and demonstrated by a physiotherapist during the first session, and adherence will be followed by telephone contact.
| Study group | Role | What they receive |
|---|---|---|
| Motivational Interviewing + Neuromuscular Exercise + Home Exercise | Experimental | Participants in this group will receive motivational interviewing in addition to a supervised neuromuscular exercise program and a home exercise program. Receives: Behavioral: Motivational Interviewing; Other: Neuromuscular Exercise Program; Other: Home Exercise Program |
| Neuromuscular Exercise Program | Active comparator | Participants will perform neuromuscular exercise sessions five times per week for four weeks. Each 60-minute session will consist of approximately 10 minutes of warm-up, 40 minutes of exercise, and 10 minutes of cool-down. Exercises will include core stabilization and postural control, postural orientation, lower-extremity strengthening, functional exercises, and balance and proprioception exercises. Exercises will be progressed according to participant tolerance and functional performance. Receives: Other: Neuromuscular Exercise Program; Other: Home Exercise Program |
What is being measured
The primary outcome is the main question the study is designed to answer.
The Exercise Self-Efficacy Scale (ESE)
The Exercise Self-Efficacy Scale (ESE) measures a person's confidence in their ability to maintain regular physical activity or exercise when facing various internal and external barriers. Different validated versions exist, including Albert Bandura's 18-item scale, an older adult 9-item scale, and a 10-item spinal cord injury adaptation.
Measured: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
Pain Self-Efficacy Questionnaire (PSEQ)
The Pain Self-Efficacy Questionnaire (PSEQ) is a 10-item self-report tool designed to measure a person's confidence in performing daily activities and functioning normally despite ongoing chronic pain. It uses a 7-point scale from 0 to 6, yielding total scores between 0 and 60, where higher scores reflect stronger coping confidence.
Measured: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
Secondary outcomes (5)
Numerical Pain Rating Scale
The Numeric Pain Rating Scale (NPRs) is a fast, 11-point tool used to measure pain intensity. Patients select a whole number from 0 (no pain) to 10 (worst pain imaginable) to rate their discomfort verbally or in writing.
Measured: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
The WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index)
The WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) is a widely used, self-administered 24-item questionnaire that evaluates pain (5 items), stiffness (2 items), and physical function (17 items) in patients with knee or hip osteoarthritis.
Measured: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention.
Physical Performance 30-Second Sit-to-Stand Test (30s STS)
The 30s STS measures lower-extremity functional strength by recording the total number of complete sit-to-stand repetitions performed within 30 seconds, with a higher number of repetitions indicating better performance.
Measured: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
Physical performance timed up and go test (TUG)
The TUG measures functional mobility as the time, in seconds, required to stand up from a chair, walk 3 meters, turn, walk back, and sit down, with a shorter completion time indicating better performance.
Measured: Baseline, immediately after 4 week intervention and 6 weeks after competition of the intervention
Physical performance 40-meter Walking Test
The 40mWT assesses walking speed by recording the time required to complete a 40-meter walking course, with a shorter completion time indicating better walking performance. The results of the three tests will be reported separately and will not be combined into a composite score.
Measured: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Aug 2026
- Study start1 Feb 2026
- Primary completion15 Nov 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee Arthritis OsteoarthritisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 56 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Kutahya Health Sciences University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ismail Saracoglu, Kutahya Health Sciences University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07767812
- Sponsor's protocol ID
- IbrahimPHDtez
- Status last verified
- Aug 2026
- First submitted
- 11 Aug 2026
- Last updated
- 17 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Effects of Motivational Interviewing on Pain Self-Efficacy and Exercise Behavior in Individuals With Knee Osteoarthritis
- ClinicalTrials.gov ID
- NCT07767812
- Acronym / sponsor ID
- IbrahimPHDtez
- Conditions
- Knee Arthritis Osteoarthritis
- Keywords
- KNEE OSTEOARTHRITIS, MOTIVATIONAL INTERVIEWING, EXERCISE
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 56 participants (estimated)
- Lead sponsor
- Kutahya Health Sciences UniversityUniversity, hospital or other
- Study start
- 1 Feb 2026 (actual)
- Primary completion
- 15 Nov 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 17 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial aims to investigate the effects of motivational interviewing added to a neuromuscular exercise and home exercise program on pain self-efficacy, exercise behavior, pain intensity, physical performance, and functional status in individuals with knee osteoarthritis. Sixty individuals diagnosed with knee osteoarthritis will be randomly allocated to either an intervention group or a control group. The intervention group will receive motivational interviewing in addition to neuromuscular exercise and a home exercise program, whereas the control group will receive neuromuscular exercise and the same home exercise program. Outcomes will be assessed at baseline, immediately after the intervention, and six weeks after the intervention.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Motivational Interviewing + Neuromuscular Exercise + Home Exercise | Experimental | Behavioral: Motivational Interviewing, Other: Neuromuscular Exercise Program, Other: Home Exercise ProgramParticipants in this group will receive motivational interviewing in addition to a supervised neuromuscular exercise program and a home exercise program. |
| Neuromuscular Exercise Program | Active comparator | Other: Neuromuscular Exercise Program, Other: Home Exercise ProgramParticipants will perform neuromuscular exercise sessions five times per week for four weeks. Each 60-minute session will consist of approximately 10 minutes of warm-up, 40 minutes of exercise, and 10 minutes of cool-down. Exercises will include core stabilization and postural control, postural orientation, lower-extremity strengthening, functional exercises, and balance and proprioception exercises. Exercises will be progressed according to participant tolerance and functional performance. |
Who may qualify
- Ages
- 40 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Diagnosis of knee osteoarthritis according to American College of Rheumatology (ACR) criteria
- Kellgren-Lawrence radiographic grade ≥2
- Knee pain lasting longer than 3 months
Key exclusion criteria (5 listed)
- History of joint arthroplasty
- Body mass index >40 kg/m²
- Neuromuscular or neurological diseases such as stroke, Parkinson's disease, or multiple sclerosis
- History of lower-extremity joint fracture
- Hip osteoarthritis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Motivational InterviewingMotivational interviewing will be delivered individually in face-to-face sessions by a researcher trained and certified in motivational interviewing. Sessions will focus on identifying individual barriers and goals, strengthening motivation and commitment to exercise, supporting self-efficacy, and preventing relapse. The intervention will incorporate three stages: increasing exercise motivation, strengthening commitment to exercise, and relapse prevention. | Behavioural | Motivational Interviewing + Neuromuscular Exercise + Home Exercise |
| Neuromuscular Exercise ProgramParticipants will perform neuromuscular exercise sessions five times per week for four weeks. Each 60-minute session will consist of approximately 10 minutes of warm-up, 40 minutes of exercise, and 10 minutes of cool-down. Exercises will include core stabilization and postural control, postural orientation, lower-extremity strengthening, functional exercises, and balance and proprioception exercises. Exercises will be progressed according to participant tolerance and functional performance. | Other | Motivational Interviewing + Neuromuscular Exercise + Home Exercise, Neuromuscular Exercise Program |
| Home Exercise ProgramThe home exercise program will include isometric strengthening exercises for the quadriceps and hip adductor muscles, straight leg raising, assisted hip and knee flexion, and active knee flexion exercises. Participants will perform the program five days per week, twice daily, for three weeks, with 10 repetitions of each exercise. The program will be explained and demonstrated by a physiotherapist during the first session, and adherence will be followed by telephone contact. | Other | Motivational Interviewing + Neuromuscular Exercise + Home Exercise, Neuromuscular Exercise Program |
Primary outcome
The Exercise Self-Efficacy Scale (ESE)
Time frame: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
The Exercise Self-Efficacy Scale (ESE) measures a person's confidence in their ability to maintain regular physical activity or exercise when facing various internal and external barriers. Different validated versions exist, including Albert Bandura's 18-item scale, an older adult 9-item scale, and a 10-item spinal cord injury adaptation.
Pain Self-Efficacy Questionnaire (PSEQ)
Time frame: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
The Pain Self-Efficacy Questionnaire (PSEQ) is a 10-item self-report tool designed to measure a person's confidence in performing daily activities and functioning normally despite ongoing chronic pain. It uses a 7-point scale from 0 to 6, yielding total scores between 0 and 60, where higher scores reflect stronger coping confidence.
5 secondary outcomes
Numerical Pain Rating Scale
Time frame: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
The WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index)
Time frame: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention.
Physical Performance 30-Second Sit-to-Stand Test (30s STS)
Time frame: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
Physical performance timed up and go test (TUG)
Time frame: Baseline, immediately after 4 week intervention and 6 weeks after competition of the intervention
Physical performance 40-meter Walking Test
Time frame: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Motivational Interviewing, Neuromuscular Exercise Program and Home Exercise Program in people with Knee Arthritis Osteoarthritis, run by Kutahya Health Sciences University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact İbrahim YUKSEL, Msc. PT (0539 222 88 46, ibrahimyuksel0308@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The Exercise Self-Efficacy Scale (ESE) (time frame: Baseline, immediately after the 4-week intervention, and 6 weeks after completion of the intervention). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2026.