StrokeR3NCT07769281
Safety and Efficacy of NeuroTechR3 System for Upper Extremity Recovery After Stroke
A study testing NeuroTechR3 Computer Rehabilitation System in people with Stroke, run by Brooks Rehabilitation at 1 site in United States.
Trial summary
This research aims to understand the feasibility and effectiveness of using the NeuroTechR3 System to improve upper extremity function after stroke. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Stroke
- What is being tested?
- NeuroTechR3 Computer Rehabilitation System
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 10 participants
- Where
- 1 siteUnited States
- Study dates
- 21 Aug 2025to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age ≥18 years at the time of enrollment
- Diagnosed with stroke
- No other peripheral or central neurological condition limiting target upper extremity function (previous stroke is ok)
- Indicated for upper extremity training procedures by participant's treating physician, occupational therapist, or physical therapist
- Capable of providing informed consent
- Participant demonstrates active extension of wrist and activation of at least two other digits plus thumb activation
Who cannot join
- In the opinion of the investigators, the study is not safe or appropriate for the participant, and/or the participant is unlikely to return for the follow-up visits per the protocol to return the device at 4 weeks post discharge
- Visual impairment that would severely limit ability to see a computer screen for participation in sessions, including severe spatial neglect making the person unable to interact with an entire computer screen
- Inability to follow a 3-step motor command
- Severe upper extremity tone that will limit participation in study
- No internet access at home
- Severe receptive aphasia
- Severe arthritis that limits hand and arm movements
- Not independent in functional activities/mobility prior to stroke
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Brooks Rehabilitation Hospital - Bartram Campus
Jacksonville, Florida, 32258
Hannah Grimes, 904-528-3159, hannah.grimes@brooksrehab.org
About this study
This research aims to understand the feasibility and effectiveness of using the NeuroTechR3 System to improve upper extremity function after stroke.
- Conditions
- Stroke
- Being tested
- NeuroTechR3 Computer Rehabilitation System
- Keywords
- stroke, upper extremity rehab
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
NeuroTechR3 Computer Rehabilitation SystemDevice
Participants will complete three sessions a week, each lasting for 30 minutes. The sessions consist of upper extremity rehabilitation games on the computer.
| Study group | Role | What they receive |
|---|---|---|
| NeuroTechR3 System | Experimental | Participants will be engaging in six weeks of intervention sessions using the NeuroTechR3 System while in the Brooks Rehabilitation Hospital under the direct supervision of a study staff member. Participants will then take the NeuroTechR3 System and a laptop home to complete intervention sessions in their home after discharge without the supervision of study staff. Each session is 30 minutes and 3 times a week. Receives: Device: NeuroTechR3 Computer Rehabilitation System |
What is being measured
The primary outcome is the main question the study is designed to answer.
Upper Extremity Strength and Function
The Fugle-Meyer test is a simple, standardized test used to assess a person's exercise capacity and functional mobility. An increase in score reflects an improvement in mobility and upper extremity function.
Measured: Pre-intervention, mid-intervention within 3 days of discharging from the inpatient rehabilitation facility, and post-intervention at 6 weeks.
Questionnaires
The System Usability Scale measures the perceived usability, ease of use, and learnability of the system. An increase in score indicates better usability.
Measured: Mid-intervention within 3 days of discharging from the inpatient rehabilitation facility and post-intervention at 6 weeks.
Secondary outcomes (1)
Care Transition
The NeuroTechR3 System evaluates range of motion, speed, and accuracy for the hand and arm. An increase in kinematic data indicates improved functioning.
Measured: Pre-intervention, mid-intervention within 3 days of discharging from the inpatient rehabilitation facility, and post-intervention at 6 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Aug 2026
- Study start21 Aug 2025
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 10 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Brooks Rehabilitation
- Sponsor type
- University, hospital or other
- Collaborators
- NeuroTechR3
- Responsible party
- Principal investigator, mark.bowden, Brooks Rehabilitation
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07769281
- Sponsor's protocol ID
- 00090019
- Acronym
- R3
- Status last verified
- Aug 2026
- First submitted
- 12 Aug 2026
- Last updated
- 17 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Safety and Efficacy of NeuroTechR3 System for Upper Extremity Recovery After Stroke
- ClinicalTrials.gov ID
- NCT07769281
- Acronym / sponsor ID
- R3 / 00090019
- Conditions
- Stroke
- Keywords
- stroke, upper extremity rehab
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 10 participants (estimated)
- Lead sponsor
- Brooks RehabilitationUniversity, hospital or other
- Collaborators
- NeuroTechR3
- Study start
- 21 Aug 2025 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 17 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This research aims to understand the feasibility and effectiveness of using the NeuroTechR3 System to improve upper extremity function after stroke.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| NeuroTechR3 System | Experimental | Device: NeuroTechR3 Computer Rehabilitation SystemParticipants will be engaging in six weeks of intervention sessions using the NeuroTechR3 System while in the Brooks Rehabilitation Hospital under the direct supervision of a study staff member. Participants will then take the NeuroTechR3 System and a laptop home to complete intervention sessions in their home after discharge without the supervision of study staff. Each session is 30 minutes and 3 times a week. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Age ≥18 years at the time of enrollment
- Diagnosed with stroke
- No other peripheral or central neurological condition limiting target upper extremity function (previous stroke is ok)
- Indicated for upper extremity training procedures by participant's treating physician, occupational therapist, or physical therapist
- Capable of providing informed consent
Key exclusion criteria (8 listed)
- In the opinion of the investigators, the study is not safe or appropriate for the participant, and/or the participant is unlikely to return for the follow-up visits per the protocol to return the device at 4 weeks post discharge
- Visual impairment that would severely limit ability to see a computer screen for participation in sessions, including severe spatial neglect making the person unable to interact with an entire computer screen
- Inability to follow a 3-step motor command
- Severe upper extremity tone that will limit participation in study
- No internet access at home
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| NeuroTechR3 Computer Rehabilitation SystemParticipants will complete three sessions a week, each lasting for 30 minutes. The sessions consist of upper extremity rehabilitation games on the computer. | Device | NeuroTechR3 System |
Primary outcome
Upper Extremity Strength and Function
Time frame: Pre-intervention, mid-intervention within 3 days of discharging from the inpatient rehabilitation facility, and post-intervention at 6 weeks.
The Fugle-Meyer test is a simple, standardized test used to assess a person's exercise capacity and functional mobility. An increase in score reflects an improvement in mobility and upper extremity function.
Questionnaires
Time frame: Mid-intervention within 3 days of discharging from the inpatient rehabilitation facility and post-intervention at 6 weeks.
The System Usability Scale measures the perceived usability, ease of use, and learnability of the system. An increase in score indicates better usability.
1 secondary outcome
Care Transition
Time frame: Pre-intervention, mid-intervention within 3 days of discharging from the inpatient rehabilitation facility, and post-intervention at 6 weeks.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing NeuroTechR3 Computer Rehabilitation System in people with Stroke, run by Brooks Rehabilitation at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Hannah Grimes (904-528-3159, hannah.grimes@brooksrehab.org), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Upper Extremity Strength and Function (time frame: Pre-intervention, mid-intervention within 3 days of discharging from the inpatient rehabilitation facility, and post-intervention at 6 weeks.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2026.