Osteoarthritis (OA) of the KneeNCT07773324
Kinesio Taping After Platelet-Rich Plasma Treatment in Individuals With Knee Osteoarthritis
A study testing Kinesio Taping in people with Osteoarthritis (OA) of the Knee, run by Agri Ibrahim Cecen University at 1 site in Turkey (Türkiye).
Trial summary
This randomized controlled study evaluated whether kinesio taping provided additional benefits compared with sham taping in women with knee osteoarthritis who had received platelet-rich plasma (PRP) treatment as part of routine clinical care. Read more about this study
- Who is it for?
- Ages 50 to 65 years, women only
- Conditions the study is for
- Osteoarthritis (OA) of the Knee
- What is being tested?
- Kinesio Taping
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 16 May 2025to 16 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 65 years
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Female participants aged 50 to 65 years
- Diagnosis of unilateral or bilateral knee osteoarthritis according to the American College of Rheumatology criteria
- Kellgren-Lawrence radiographic grade 1 to 3 knee osteoarthritis
- Received three platelet-rich plasma injections at 3-week intervals as part of routine clinical care
- Ability to walk without an assistive device
- Body mass index below 35 kg/m²
- Willingness to participate and provision of written informed consent
Who cannot join
- Knee surgery within the previous 6 months
- Intra-articular injection other than platelet-rich plasma within the previous 3 months
- Systemic inflammatory joint disease, including rheumatoid arthritis, ankylosing spondylitis, or gout
- Known allergy or adverse skin reaction to kinesio tape
- Skin condition preventing tape application, including skin sensitivity or an open wound
- Neuromuscular disease causing lower-extremity muscle weakness
- Perceptual or coordination impairment
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Kafkas University Health Research and Application Hospital
Kars, 36100
About this study
Official title: The Efficacy of the Combined Use of Platelet-Rich Plasma and Kinesio Taping in Individuals With Knee Osteoarthritis: A Randomized Controlled Trial
This randomized controlled study evaluated whether kinesio taping provided additional benefits compared with sham taping in women with knee osteoarthritis who had received platelet-rich plasma (PRP) treatment as part of routine clinical care. Sixty women aged 50 to 65 years with Kellgren-Lawrence grade 1 to 3 knee osteoarthritis were randomly assigned in a 1:1 ratio to either kinesio taping or sham taping. Taping was applied once weekly for 6 weeks. Participants were assessed before taping and at weeks 3, 6, and 12. Outcomes included pain, function, physical performance, knee extensor strength, knee range of motion, and quality of life. The study aimed to determine whether kinesio taping after PRP treatment was more effective than sham taping in improving pain, function, physical performance, knee extensor strength, knee range of motion and quality of life.
- Conditions
- Osteoarthritis (OA) of the Knee
- Being tested
- Kinesio Taping, Sham Taping
- Keywords
- Kinesio Taping, Platelet-Rich Plasma, Sham Taping, Knee Pain, Physical Function
- Medical subject headings
- Osteoarthritis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Kinesio TapingOther
Therapeutic kinesio taping was applied once weekly for 6 weeks. A Y-cut tape was applied over the quadriceps muscle with 20% to 25% tension. Two web-cut tapes were applied around the knee with 10% to 15% tension. Each application remained in place for 5 days.
Sham TapingOther
Sham taping was applied once weekly for 6 weeks. Two strips of tape were placed transversely 10 cm and 20 cm above the superior border of the patella without tape tension or a specific kinesio taping technique. Each application remained in place for 5 days.
| Study group | Role | What they receive |
|---|---|---|
| Kinesio Taping | Experimental | Not described Receives: Other: Kinesio Taping |
| Sham Taping | Sham comparator | Not described Receives: Other: Sham Taping |
What is being measured
The primary outcome is the main question the study is designed to answer.
Knee Pain Intensity
Knee pain was assessed using an 11-point Numerical Rating Scale ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores indicate greater pain intensity.
Measured: Baseline and Weeks 3, 6, and 12
Function ((Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC))
Knee pain, stiffness, and physical function were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The pain, stiffness, and physical function subscale scores range from 0 to 20, 0 to 8, and 0 to 68, respectively. The total score ranges from 0 to 96. Higher scores indicate worse pain, stiffness, and functional limitation.
Measured: Baseline and Weeks 3, 6, and 12
Secondary outcomes (7)
30-Second Chair Stand Test
Functional performance was assessed using the 30-Second Chair Stand Test. The number of complete stands performed from a 44-cm-high chair within 30 seconds was recorded. A higher number of completed stands indicates better functional performance.
Measured: Baseline and Weeks 3, 6, and 12
40-Meter Fast-Paced Walk Test
Functional walking performance was assessed using the 40-Meter Fast-Paced Walk Test. The time required to complete a total distance of 40 meters was recorded in seconds. A shorter completion time indicates better walking performance.
Measured: Baseline and Weeks 3, 6, and 12
9-Step Stair Test
Stair performance was assessed by recording the time required to ascend and descend 9 steps as quickly and safely as possible without assistance. The completion time was recorded in seconds. A shorter time indicates better functional performance.
Measured: Baseline and Weeks 3, 6, and 12
Knee Extensor Strength
Maximal isometric knee extensor muscle strength was measured using a hand-held dynamometer with the hip and knee positioned at 90 degrees of flexion. Three measurements were performed, and the mean value was recorded in kilograms. Higher values indicate greater muscle strength.
Measured: Baseline and Weeks 3, 6, and 12
Knee Flexion Range of Motion
Active knee flexion range of motion was measured using a universal goniometer. Three measurements were performed, and the mean value was recorded in degrees.
Measured: Baseline and Weeks 3, 6, and 12
Knee Extension Range of Motion
Active knee extension range of motion was measured using a universal goniometer. Three measurements were performed, and the mean value was recorded in degrees.
Measured: Baseline and Weeks 3, 6, and 12
Change in 36-Item Short Form Health Survey (SF-36) Domain Scores
Quality of life was assessed using the 36-Item Short Form Health Survey (SF-36). The instrument evaluates eight domains: physical functioning, physical role limitations, emotional role limitations, emotional well-being, social functioning, energy/fatigue, bodily pain, and general health. Each domain is scored from 0 to 100, with higher scores indicating better health-related quality of life.
Measured: Baseline and Weeks 3, 6, and 12
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Aug 2026
- Study start16 May 2025
- Primary completion16 May 2026
- Study completion16 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Osteoarthritis (OA) of the KneeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Agri Ibrahim Cecen University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Kübra Ayşe Daşdemir, Agri Ibrahim Cecen University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07773324
- Sponsor's protocol ID
- 2024-1296
- Other IDs
- 125S162
- Status last verified
- Aug 2026
- First submitted
- 14 Aug 2026
- Last updated
- 19 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Efficacy of the Combined Use of Platelet-Rich Plasma and Kinesio Taping in Individuals With Knee Osteoarthritis: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07773324
- Acronym / sponsor ID
- 2024-1296
- Conditions
- Osteoarthritis (OA) of the Knee
- Keywords
- Kinesio Taping, Platelet-Rich Plasma, Sham Taping, Knee Pain, Physical Function
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Agri Ibrahim Cecen UniversityUniversity, hospital or other
- Study start
- 16 May 2025 (actual)
- Primary completion
- 16 May 2026 (actual)
- Study completion
- 16 May 2026 (actual)
- First posted
- 19 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled study evaluated whether kinesio taping provided additional benefits compared with sham taping in women with knee osteoarthritis who had received platelet-rich plasma (PRP) treatment as part of routine clinical care. Sixty women aged 50 to 65 years with Kellgren-Lawrence grade 1 to 3 knee osteoarthritis were randomly assigned in a 1:1 ratio to either kinesio taping or sham taping. Taping was applied once weekly for 6 weeks. Participants were assessed before taping and at weeks 3, 6, and 12. Outcomes included pain, function, physical performance, knee extensor strength, knee range of motion, and quality of life. The study aimed to determine whether kinesio taping after PRP treatment was more effective than sham taping in improving pain, function, physical performance, knee extensor strength, knee range of motion and quality of life.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Kinesio Taping | Experimental | Other: Kinesio Taping |
| Sham Taping | Sham comparator | Other: Sham Taping |
Who may qualify
- Ages
- 50 to 65 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (7 listed)
- Female participants aged 50 to 65 years
- Diagnosis of unilateral or bilateral knee osteoarthritis according to the American College of Rheumatology criteria
- Kellgren-Lawrence radiographic grade 1 to 3 knee osteoarthritis
- Received three platelet-rich plasma injections at 3-week intervals as part of routine clinical care
- Ability to walk without an assistive device
Key exclusion criteria (7 listed)
- Knee surgery within the previous 6 months
- Intra-articular injection other than platelet-rich plasma within the previous 3 months
- Systemic inflammatory joint disease, including rheumatoid arthritis, ankylosing spondylitis, or gout
- Known allergy or adverse skin reaction to kinesio tape
- Skin condition preventing tape application, including skin sensitivity or an open wound
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Kinesio TapingTherapeutic kinesio taping was applied once weekly for 6 weeks. A Y-cut tape was applied over the quadriceps muscle with 20% to 25% tension. Two web-cut tapes were applied around the knee with 10% to 15% tension. Each application remained in place for 5 days. | Other | Kinesio Taping |
| Sham TapingSham taping was applied once weekly for 6 weeks. Two strips of tape were placed transversely 10 cm and 20 cm above the superior border of the patella without tape tension or a specific kinesio taping technique. Each application remained in place for 5 days. | Other | Sham Taping |
Primary outcome
Knee Pain Intensity
Time frame: Baseline and Weeks 3, 6, and 12
Knee pain was assessed using an 11-point Numerical Rating Scale ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores indicate greater pain intensity.
Function ((Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC))
Time frame: Baseline and Weeks 3, 6, and 12
Knee pain, stiffness, and physical function were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The pain, stiffness, and physical function subscale scores range from 0 to 20, 0 to 8, and 0 to 68, respectively. The total score ranges from 0 to 96. Higher scores indicate worse pain, stiffness, and functional limitation.
7 secondary outcomes
30-Second Chair Stand Test
Time frame: Baseline and Weeks 3, 6, and 12
40-Meter Fast-Paced Walk Test
Time frame: Baseline and Weeks 3, 6, and 12
9-Step Stair Test
Time frame: Baseline and Weeks 3, 6, and 12
Knee Extensor Strength
Time frame: Baseline and Weeks 3, 6, and 12
Knee Flexion Range of Motion
Time frame: Baseline and Weeks 3, 6, and 12
Knee Extension Range of Motion
Time frame: Baseline and Weeks 3, 6, and 12
Change in 36-Item Short Form Health Survey (SF-36) Domain Scores
Time frame: Baseline and Weeks 3, 6, and 12
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Kinesio Taping in people with Osteoarthritis (OA) of the Knee, run by Agri Ibrahim Cecen University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Knee Pain Intensity (time frame: Baseline and Weeks 3, 6, and 12). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Aug 2026.