Memory DisordersNCT07773493
A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social Engagement
A study testing Social Reminder System in people with Memory Disorders and Mild Cognitive Impairment, run by University of Minnesota at 1 site in United States.
Trial summary
This study will evaluate the Social Reminder System, a mobile informatics system designed to support persons with memory concerns and their care partners. The system is intended to aid social integration for persons with memory concerns and improve care coordination and reduce caregiver burden among caregivers. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Memory Disorders, Mild Cognitive Impairment, Dementia
- What is being tested?
- Social Reminder System
- Type of treatment
- Pill or oral medicine, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 200 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Nov 2026to Jun 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Persons with memory concerns must be English speaking.
- Persons with memory concerns must self-report a healthcare provider visit due to memory concerns or memory related diagnosis by a physician or other qualified health care provider consistent with having mild-to-moderate memory impairment.
- Persons with memory concerns must be over the age of 65.
- Persons with memory concerns must be able to formally consent or assent to participate in the study.
- Persons with memory concerns must have internet access.
- Care partners of persons with memory concerns must speak English.
Show all 10Show fewer
- Care partners must be 18 years of age and over.
- Care partners must self-identify as the primary caregiver for the person with memory concerns.
- Care partners must indicate a willingness to use the Social Reminder System as well as to being randomized to a control group.
- Care partners must have a mobile phone with internet access in order to install and use the care partner app.
Who cannot join
- Those who do not meet the criteria above will be excluded.
- Persons with memory concerns with severe or no dementia are not eligible.
- Individuals who score below 6 and above 24 on the TICS-40 will not be eligible.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
University Of Minnesota
Minneapolis, Minnesota, 55455
Hannah Wheeler, 612-624-2642, hwheeler@umn.edu
Jude Mikal, PhD
About this study
This study will evaluate the Social Reminder System, a mobile informatics system designed to support persons with memory concerns and their care partners. The system is intended to aid social integration for persons with memory concerns and improve care coordination and reduce caregiver burden among caregivers.
Researchers will enroll 100 persons with memory concerns and their care partners. Half of the dyads will be randomly assigned to receive the Social Reminder System technology for a 6-month period, and the other half will be randomly assigned to the usual care control group. Participants will complete baseline, 3-month, and 6-month surveys. A subset of participants who receive the technology will also be asked to complete a semi-structured interview after the 6-month survey.
Read the detailed description
The Social Reminder System has two goals. The first is to aid in the social integration of persons with memory concerns. The second is to improve care coordination and reduce caregiver burden among caregivers. Following a randomized control trial design, the study will assess the impact of the Social Reminder System on both persons with memory concerns and their care partners.
The Social Reminder System app is designed to provide memory prompts to persons with memory concerns on an in-home tablet before and during social visits. Individuals who are part of a person with memory concerns' trusted circle may download a free smartphone app and save a photo of themselves, their names, and familial relationship description that are shared with the person with memory concerns' display. When trusted circle members are within a 10-meter range of the tablet, the person with memory concerns receives a notification that a visitor is in range. The notification includes a photo of the visitor, the visitor's name, and information about their relationship to the person with memory concerns. Reminders continue to appear on the tablet throughout the visit and cease once the visitor is out of range.
The phase 2b technology also allows the person with memory concerns to designate a primary caregiver. For security reasons and to promote care coordination, the care partner will receive a log of visitors who opted in as trusted circle members. The log will include names, dates, and beginning and ending times of each visit.
A total of 100 dyads, consisting of persons with memory concerns and their care partners, will be enrolled. Half of the dyads will be randomly assigned to the Social Reminder System intervention group and half to an attention control group. Participants will complete baseline, 3-month, and 6-month surveys. The baseline survey will be administered before exposure to the intervention or attention control. Follow-up surveys will be administered 3 months and 6 months after enrollment.
The study will also include semi-structured interviews with a subset of dyads randomly assigned to receive the Social Reminder System. Interviews will take place after completion of the final 6-month follow-up survey and will focus on overall reactions to the technology, perceived barriers to engagement with the technology, and short- and long-term outcomes of engagement with the technology that may have been missed in the survey instruments.
- Being tested
- Social Reminder System
- Keywords
- Social Reminder System, SRS, Persons with memory concerns, Social engagement, Mobile health, Care coordination, Alzheimer's disease and related dementias, Mild-to-moderate memory impairment, Caregiver stress
- Medical subject headings
- Memory Disorders, Cognitive Dysfunction, Dementia, Social Isolation, Caregiver Burden, Alzheimer Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Social Reminder SystemBehavioural
The Social Reminder System app is designed to provide memory prompts to persons with memory concerns on an in-home tablet before and during social visits. Individuals who are part of a person with memory concerns' trusted circle may download a free smartphone app and save a photo of themselves, their names, and familial relationship description that are shared with the person with memory concerns' display. When trusted circle members are within a 10 meter range of the tablet, the person with memory concerns receives a notification that a visitor is in range. Reminders continue to appear on the tablet throughout the visit and cease once the visitor is out of range. The care partner will also receive a log of visitors, including names, dates, and beginning and ending times of each visit.
| Study group | Role | What they receive |
|---|---|---|
| Social Reminder System | Experimental | Dyads randomly assigned to this arm will receive the Social Reminder System technology for a 6-month period. The Social Reminder System app is designed to provide memory prompts to persons with memory concerns on an in-home tablet before and during social visits. Care partners will also receive a log of visitors to promote care coordination. Receives: Behavioral: Social Reminder System |
| Usual Care Control | No intervention | Dyads randomly assigned to this arm will receive usual care control. The attention control group will receive a 3-month contact call and a 6-month contact call from the research coordinator. Free information resources, such as brochures or websites of the Alzheimer's Association, may be provided. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Social Interaction Frequency and Quality
Change in frequency and quality of social interactions reported by persons with memory concerns and care partners, including in-person visits, phone calls, mail and letters, and computer-mediated communication.
Measured: Baseline to 6 months
Change in Pleasant Events and Social Engagement as Assessed by the Pleasant Events Schedule-Alzheimer's Disease
Change in pleasant events and social engagement for persons with memory concerns, assessed using the Pleasant Events Schedule-AD.
Measured: Baseline to 6 months
Change in Social Support Score
Change in social support among persons with memory concerns and care partners, assessed using a five-item social support scale.
Measured: Baseline to 6 months
Change in Loneliness
Change in loneliness among persons with memory concerns and care partners, assessed using the UCLA Loneliness Scale.
Measured: Baseline to 6 months
Change in Caregiver Burden
Change in caregiver burden among care partners, assessed using the Zarit Burden Interview.
Measured: Baseline to 6 months
Change in Role Captivity Score
Change in role captivity among care partners, assessed using a 4-item role captivity scale.
Measured: Baseline to 6 months
Change in Role Overload Score
Change in role overload among care partners, assessed using a 3-item role overload scale.
Measured: Baseline to 6 months
Change in Anxiety as Assessed by the Hospital Anxiety and Depression Scale
Change in anxiety among persons with memory concerns and care partners, assessed using the Hospital Anxiety and Depression Scale.
Measured: Baseline to 6 months
Change in Depression as Assessed by the Hospital Anxiety and Depression Scale
Change in depression among persons with memory concerns and care partners, assessed using the Hospital Anxiety and Depression Scale.
Measured: Baseline to 6 months
Secondary outcomes (5)
Perceived Function, Utility, and Barriers to Engagement With the Social Reminder System
Semi-structured interviews will assess overall reactions to the Social Reminder System, perceived barriers to engagement with the technology, and short- and long-term outcomes of engagement with the technology that may have been missed in the survey instruments.
Measured: Up to 1 month after completion of the 6-month follow-up survey
Change in Service Utilization Among Persons With Memory Concerns
Change in service utilization among persons with memory concerns, including nursing home, assisted living, other residential care, hospital stays, and emergency department visits.
Measured: Baseline to 6 months
Change in Negative Health Transitions Among Persons With Memory Concerns
Change in negative health transitions among persons with memory concerns, including falls and wandering events, assessed by care partner report.
Measured: Baseline to 6 months
Change in Quality of Life as Assessed by the Adapted Quality of Life-Alzheimer's Disease Measure
Change in quality of life for persons with memory concerns and care partners, assessed using the adapted Quality of Life-Alzheimer's Disease measure.
Measured: Baseline to 6 months
Change in Community Engagement as Assessed by the 15-Item Community Engagement Scale
Change in community engagement among persons with memory concerns and care partners, assessed using a 15-item scale evaluating frequency, duration, and location of trips outside the home.
Measured: Baseline to 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Aug 2026
- Study start1 Nov 2026 (estimated)
- Primary completionMar 2028 (estimated)
- Study completionJun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Memory DisordersStudies of the same condition, open and under way.
- More trials run by University of MinnesotaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Half of the dyads will be randomly assigned to receive the Social Reminder System technology for a 6-month period and the other half will be randomly assigned to the usual care control group.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Minnesota
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Aging (NIA)
- Responsible party
- Sponsor
- Investigators
- Jude Mikal, PhD, Principal investigator, University of Minnesota
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07773493
- Sponsor's protocol ID
- Study00027433
- Other IDs
- 2R44AG063683-04
- Status last verified
- Aug 2026
- First submitted
- 13 Aug 2026
- Last updated
- 19 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social Engagement
- ClinicalTrials.gov ID
- NCT07773493
- Acronym / sponsor ID
- Study00027433
- Keywords
- Social Reminder System, SRS, Persons with memory concerns, Social engagement, Mobile health, Care coordination, Alzheimer's disease and related dementias, Mild-to-moderate memory impairment
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- University of MinnesotaUniversity, hospital or other
- Collaborators
- National Institute on Aging (NIA)
- Study start
- 1 Nov 2026 (estimated)
- Primary completion
- Mar 2028 (estimated)
- Study completion
- Jun 2028 (estimated)
- First posted
- 19 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will evaluate the Social Reminder System, a mobile informatics system designed to support persons with memory concerns and their care partners. The system is intended to aid social integration for persons with memory concerns and improve care coordination and reduce caregiver burden among caregivers.
Researchers will enroll 100 persons with memory concerns and their care partners. Half of the dyads will be randomly assigned to receive the Social Reminder System technology for a 6-month period, and the other half will be randomly assigned to the usual care control group. Participants will complete baseline, 3-month, and 6-month surveys. A subset of participants who receive the technology will also be asked to complete a semi-structured interview after the 6-month survey.
Detailed description
The Social Reminder System has two goals. The first is to aid in the social integration of persons with memory concerns. The second is to improve care coordination and reduce caregiver burden among caregivers. Following a randomized control trial design, the study will assess the impact of the Social Reminder System on both persons with memory concerns and their care partners.
The Social Reminder System app is designed to provide memory prompts to persons with memory concerns on an in-home tablet before and during social visits. Individuals who are part of a person with memory concerns' trusted circle may download a free smartphone app and save a photo of themselves, their names, and familial relationship description that are shared with the person with memory concerns' display. When trusted circle members are within a 10-meter range of the tablet, the person with memory concerns receives a notification that a visitor is in range. The notification includes a photo of the visitor, the visitor's name, and information about their relationship to the person with memory concerns. Reminders continue to appear on the tablet throughout the visit and cease once the visitor is out of range.
The phase 2b technology also allows the person with memory concerns to designate a primary caregiver. For security reasons and to promote care coordination, the care partner will receive a log of visitors who opted in as trusted circle members. The log will include names, dates, and beginning and ending times of each visit.
A total of 100 dyads, consisting of persons with memory concerns and their care partners, will be enrolled. Half of the dyads will be randomly assigned to the Social Reminder System intervention group and half to an attention control group. Participants will complete baseline, 3-month, and 6-month surveys. The baseline survey will be administered before exposure to the intervention or attention control. Follow-up surveys will be administered 3 months and 6 months after enrollment.
The study will also include semi-structured interviews with a subset of dyads randomly assigned to receive the Social Reminder System. Interviews will take place after completion of the final 6-month follow-up survey and will focus on overall reactions to the technology, perceived barriers to engagement with the technology, and short- and long-term outcomes of engagement with the technology that may have been missed in the survey instruments.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Half of the dyads will be randomly assigned to receive the Social Reminder System technology for a 6-month period and the other half will be randomly assigned to the usual care control group.
| Arm | Type | Receives |
|---|---|---|
| Social Reminder System | Experimental | Behavioral: Social Reminder SystemDyads randomly assigned to this arm will receive the Social Reminder System technology for a 6-month period. The Social Reminder System app is designed to provide memory prompts to persons with memory concerns on an in-home tablet before and during social visits. Care partners will also receive a log of visitors to promote care coordination. |
| Usual Care Control | No intervention | –Dyads randomly assigned to this arm will receive usual care control. The attention control group will receive a 3-month contact call and a 6-month contact call from the research coordinator. Free information resources, such as brochures or websites of the Alzheimer's Association, may be provided. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (10 listed)
- Persons with memory concerns must be English speaking.
- Persons with memory concerns must self-report a healthcare provider visit due to memory concerns or memory related diagnosis by a physician or other qualified health care provider consistent with having mild-to-moderate memory impairment.
- Persons with memory concerns must be over the age of 65.
- Persons with memory concerns must be able to formally consent or assent to participate in the study.
- Persons with memory concerns must have internet access.
Key exclusion criteria (3 listed)
- Those who do not meet the criteria above will be excluded.
- Persons with memory concerns with severe or no dementia are not eligible.
- Individuals who score below 6 and above 24 on the TICS-40 will not be eligible.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Social Reminder SystemThe Social Reminder System app is designed to provide memory prompts to persons with memory concerns on an in-home tablet before and during social visits. Individuals who are part of a person with memory concerns' trusted circle may download a free smartphone app and save a photo of themselves, their names, and familial relationship description that are shared with the person with memory concerns' display. When trusted circle members are within a 10 meter range of the tablet, the person with memory concerns receives a notification that a visitor is in range. Reminders continue to appear on the tablet throughout the visit and cease once the visitor is out of range. The care partner will also receive a log of visitors, including names, dates, and beginning and ending times of each visit. | Behavioural | Social Reminder System |
Primary outcome
Change in Social Interaction Frequency and Quality
Time frame: Baseline to 6 months
Change in frequency and quality of social interactions reported by persons with memory concerns and care partners, including in-person visits, phone calls, mail and letters, and computer-mediated communication.
Change in Pleasant Events and Social Engagement as Assessed by the Pleasant Events Schedule-Alzheimer's Disease
Time frame: Baseline to 6 months
Change in pleasant events and social engagement for persons with memory concerns, assessed using the Pleasant Events Schedule-AD.
Change in Social Support Score
Time frame: Baseline to 6 months
Change in social support among persons with memory concerns and care partners, assessed using a five-item social support scale.
Change in Loneliness
Time frame: Baseline to 6 months
Change in loneliness among persons with memory concerns and care partners, assessed using the UCLA Loneliness Scale.
Change in Caregiver Burden
Time frame: Baseline to 6 months
Change in caregiver burden among care partners, assessed using the Zarit Burden Interview.
Change in Role Captivity Score
Time frame: Baseline to 6 months
Change in role captivity among care partners, assessed using a 4-item role captivity scale.
Change in Role Overload Score
Time frame: Baseline to 6 months
Change in role overload among care partners, assessed using a 3-item role overload scale.
Change in Anxiety as Assessed by the Hospital Anxiety and Depression Scale
Time frame: Baseline to 6 months
Change in anxiety among persons with memory concerns and care partners, assessed using the Hospital Anxiety and Depression Scale.
Change in Depression as Assessed by the Hospital Anxiety and Depression Scale
Time frame: Baseline to 6 months
Change in depression among persons with memory concerns and care partners, assessed using the Hospital Anxiety and Depression Scale.
5 secondary outcomes
Perceived Function, Utility, and Barriers to Engagement With the Social Reminder System
Time frame: Up to 1 month after completion of the 6-month follow-up survey
Change in Service Utilization Among Persons With Memory Concerns
Time frame: Baseline to 6 months
Change in Negative Health Transitions Among Persons With Memory Concerns
Time frame: Baseline to 6 months
Change in Quality of Life as Assessed by the Adapted Quality of Life-Alzheimer's Disease Measure
Time frame: Baseline to 6 months
Change in Community Engagement as Assessed by the 15-Item Community Engagement Scale
Time frame: Baseline to 6 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Jude Mikal, PhD principal investigator
University of Minnesota
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Social Reminder System in people with Memory Disorders and Mild Cognitive Impairment, run by University of Minnesota at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 10 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 19 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Hannah Wheeler (612-624-2642, hwheeler@umn.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Social Interaction Frequency and Quality (time frame: Baseline to 6 months). The study lists 9 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Aug 2026.