Postoperative PainNCT07775053
Efficacy of Tramadol With Ropivacaine for Modified Pectoral Nerve Block in Breast Cancer Surgery
A study testing Pectoral Nerve Block in people with Postoperative Pain, run by Sargodha Medical College at 1 site in Pakistan.
Trial summary
In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy. The patients will be divided into two groups one group will receive modified pectoral nerve block with local anesthetic ropivacaine combined with tramadol and other group will receive… Read more about this study
- Who is it for?
- Ages 20 to 70 yearsHealthy volunteers can take part
- Conditions the study is for
- Postoperative Pain
- What is being tested?
- Pectoral Nerve Block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 62 participants
- Where
- 1 sitePakistan
- Study dates
- 22 Jan 2026to Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 70 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Female Patients aged 20-70 years
- Patients scheduled for elective unilateral modified radical mastectomy
- Patients with ASAI andII physical status.
Who cannot join
- Patients on anticoagulant therapy.
- Patients with a BMI≥35 kg/m3.
- Patients with a history of allergy to local anesthetics.
- Patients with significant neurological or psychiatric disorders.
- Pregnant patients.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site
Dr Faisal Masood teaching Hospital Sargodha
Sargodha, Punjab Province, 40100
About this study
Official title: Comparison of Post Operative Analgesia Between 0.25% Ropivacaine and 0.25% Ropivacaine Combined With Tramadol in Ultrasound Guided Modified Pectoral Nerve Block for Patient Undergoing Modified Radical Mastectomy.
In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy. The patients will be divided into two groups one group will receive modified pectoral nerve block with local anesthetic ropivacaine combined with tramadol and other group will receive pectoral nerve block with ropivacaine only
- Conditions
- Postoperative Pain
- Being tested
- Pectoral Nerve Block
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pectoral Nerve BlockProcedure or surgery
One group will receive ropivacaine with tramadol in modified pectoral nerve block
Pectoral Nerve BlockProcedure or surgery
This group will receive ropivacaine only.
| Study group | Role | What they receive |
|---|---|---|
| Ropivacaine with tramadol | Other | Not described Receives: Procedure: Pectoral Nerve Block |
| Ropivacaine Alone | Other | Not described Receives: Procedure: Pectoral Nerve Block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Pain with visual analogue scale
Post operatively pain will be accessed by visual analogue scale . Visual analogue scale (VAS) scale has score from 0 to 10 where 0 score indicate no or minimal pain and score of 10 indicate worst possible pain.
Measured: 24 hours postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Aug 2026
- Study start22 Jan 2026
- Primary completionAug 2027 (estimated)
- Study completionAug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 62 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sargodha Medical College
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07775053
- Sponsor's protocol ID
- SMC-ANS-2025-002
- Status last verified
- Aug 2026
- First submitted
- 15 Aug 2026
- Last updated
- 24 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Post Operative Analgesia Between 0.25% Ropivacaine and 0.25% Ropivacaine Combined With Tramadol in Ultrasound Guided Modified Pectoral Nerve Block for Patient Undergoing Modified Radical Mastectomy.
- ClinicalTrials.gov ID
- NCT07775053
- Acronym / sponsor ID
- SMC-ANS-2025-002
- Conditions
- Postoperative Pain
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 62 participants (estimated)
- Lead sponsor
- Sargodha Medical CollegeUniversity, hospital or other
- Study start
- 22 Jan 2026 (actual)
- Primary completion
- Aug 2027 (estimated)
- Study completion
- Aug 2027 (estimated)
- First posted
- 20 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy. The patients will be divided into two groups one group will receive modified pectoral nerve block with local anesthetic ropivacaine combined with tramadol and other group will receive pectoral nerve block with ropivacaine only
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Ropivacaine with tramadol | Other | Procedure: Pectoral Nerve Block |
| Ropivacaine Alone | Other | Procedure: Pectoral Nerve Block |
Who may qualify
- Ages
- 20 to 70 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Female Patients aged 20-70 years
- Patients scheduled for elective unilateral modified radical mastectomy
- Patients with ASAI andII physical status.
Key exclusion criteria (5 listed)
- Patients on anticoagulant therapy.
- Patients with a BMI≥35 kg/m3.
- Patients with a history of allergy to local anesthetics.
- Patients with significant neurological or psychiatric disorders.
- Pregnant patients.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pectoral Nerve BlockOne group will receive ropivacaine with tramadol in modified pectoral nerve block | Procedure or surgery | Ropivacaine with tramadol |
| Pectoral Nerve BlockThis group will receive ropivacaine only. | Procedure or surgery | Ropivacaine Alone |
Primary outcome
Postoperative Pain with visual analogue scale
Time frame: 24 hours postoperatively
Post operatively pain will be accessed by visual analogue scale . Visual analogue scale (VAS) scale has score from 0 to 10 where 0 score indicate no or minimal pain and score of 10 indicate worst possible pain.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Pectoral Nerve Block in people with Postoperative Pain, run by Sargodha Medical College at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 24 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Pain with visual analogue scale (time frame: 24 hours postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Aug 2026.