Comparison of Two Drugs Bupivacaine and Ropivacaine for Postoperative Analgesia in Bilateral Superficial Cervical Plexus Block After Thyroidectomy

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

• Ages 20 to 40 years
• All sexes
• Healthy volunteers accepted
• Adult

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

About this study

Official title: Comparison of Postoperative Analgesia Using Bupivacaine vs Ropivacaine With Bilateral Superficial Cervical Plexus Block After Thyroidectomy

Conditions

Postoperative Pain

Being tested

Group 1 will receive 10ml of 0.25% bupivacaine, Group 2 will receive 10ml of 0.25% ropivacaine on each side.

Medical subject headings

Pain, Postoperative

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

• Group 1 will receive 10ml of 0.25% bupivacaineProcedure or surgery

  After placing the patients in a supine position with the neck slightly extended and rotated away from the side to be blocked,the procedure will be performed under sterile aseptic conditions.The sternocleidomastoid muscle will be identified,and a high-frequency (1O MHz) linear probe will be positioned transversely over the muscle,between the mastoid and clavicle. The cutaneous nerves of the cervical plexus,visible as round hypoechoic structures in the fascial plane beneath the muscle,will be targeted using a 22-gauge short block needle (5 cm) inserted in-plane with the transducer. Negative aspiration will be performed during injection to avoid inadvertent intravascular delivery. An emergency crash cart will remain available throughout the procedure.

• Group 2 will receive 10ml of 0.25% ropivacaine on each side.Procedure or surgery

  After placing the patients in a supine position with the neck slightly extended and rotated away from the side to be blocked,the procedure will be performed under sterile aseptic conditions.The sternocleidomastoid muscle will be identified,and a high-frequency (1O MHz) linear probe will be positioned transversely over the muscle,between the mastoid and clavicle. The cutaneous nerves of the cervical plexus,visible as round hypoechoic structures in the fascial plane beneath the muscle,will be targeted using a 22-gauge short block needle (5 cm) inserted in-plane with the transducer. Negative aspiration will be performed during injection to avoid inadvertent intravascular delivery. An emergency crash cart will remain available throughout the procedure

What is being measured

The primary outcome is the main question the study is designed to answer.

1. Postoperative pain

   Measured: 24 hours post surgery

2. time to the first request for analgesia

   Measured: 24 hours postoperatively

3. Block-related complications

   Measured: immediately after the intervention/procedure

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1. First posted21 Aug 2026
2. Study start22 Jan 2026
3. Primary completionDec 2026 (estimated)
4. Study completionDec 2026 (estimated)

Resources

• Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
• Other trials for Postoperative PainStudies of the same condition, open and under way.
• What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.