Facial ParalysisNCT07780370
Video-Based Facial Movement Analysis in Facial Paralysis
An observational study of Facial Paralysis, run by Biruni University at 1 site in Turkey (Türkiye).
Trial summary
This study aims to evaluate facial movements in patients with facial paralysis using video-based objective analysis and to examine the relationship between these video-based measurements and standard clinical assessment scales. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Facial Paralysis
- What is being tested?
- Video-Based Objective Facial Motion Analysis
- How many people
- 49 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Sep 2026to 20 Jun 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult patients diagnosed with facial paralysis presenting for clinical evaluation.
Who may be able to join
- Diagnosis of facial paralysis (e.g., Bell's palsy)
- Age 18 years and older
- Willing and able to provide informed consent
Who cannot join
- Presence of other neurological or craniofacial conditions affecting facial movement
- Prior facial surgery affecting facial musculature
- Inability to cooperate with video recording or clinical assessment procedures
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Zeynep Hoşbay, Proff. contact
Turkey (Türkiye)1 site
Biruni University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation
Istanbul, Istanbul, 34015
Belen Battal, PT, +90 538 864 00 94, 241119002@st.biruni.edu.tr
About this study
Official title: Investigation of the Relationship Between Video-Based Objective Facial Movement Analysis and Clinical Assessment Scales in Patients With Facial Paralysis
This study aims to evaluate facial movements in patients with facial paralysis using video-based objective analysis and to examine the relationship between these video-based measurements and standard clinical assessment scales. Participants will be asked to perform simple facial movements, such as raising the eyebrows, closing the eyes tightly, smiling, showing the teeth, pursing the lips, and puffing the cheeks, while a video recording is taken. Researchers will also evaluate participants' facial function using established clinical rating scales and questionnaires. No medication will be given, no invasive procedures will be performed, and no changes will be made to participants' current treatment. The goal is to contribute to the development of more detailed, objective, and standardized methods for evaluating facial function in patients with facial paralysis.
- Conditions
- Facial Paralysis
- Being tested
- Video-Based Objective Facial Motion Analysis
- Keywords
- Facial Paralysis, Video-Based Analysis, Facial Movement Analysis, Objective Facial Assessment, Clinical Assessment Scales
- Medical subject headings
- Facial Paralysis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Video-Based Objective Facial Motion AnalysisDiagnostic test
Video recording of standardized facial movements (eyebrow raise, eye closure, smile, teeth showing, lip pursing, cheek puffing) followed by objective, video-based analysis and comparison with clinical facial assessment scales. This is a non-therapeutic, non-invasive assessment procedure and does not constitute a treatment intervention.
| Study group | Role | What they receive |
|---|---|---|
| Facial Paralysis Patients | Patients diagnosed with facial paralysis who underwent a single evaluation session including video-based objective facial motion analysis and clinical facial function assessment scales. Receives: Diagnostic Test: Video-Based Objective Facial Motion Analysis |
What is being measured
The primary outcome is the main question the study is designed to answer.
Agreement Between Video-Based Objective Facial Motion Analysis and Clinical Facial Assessment Scale Scores
The degree of agreement/correlation between facial movement parameters obtained from video-based objective analysis and scores obtained from standardized clinical facial assessment scales, evaluated during the same session.
Measured: Single assessment session (Day 1)
Sunnybrook Facial Grading System
The Sunnybrook Facial Grading System (SFGS) is a clinician-rated outcome measure used to assess facial nerve function in individuals with facial paralysis. The scale evaluates three components: resting facial symmetry, voluntary facial movement, and synkinesis. Resting symmetry is assessed in the eye, cheek (nasolabial fold), and mouth regions, while voluntary movement is evaluated during five standardized facial expressions. Synkinesis is scored based on the presence and severity of involuntary associated movements during voluntary facial tasks. The composite score is calculated using the standard Sunnybrook scoring formula and ranges from 0 to 100, where 0 indicates complete facial paralysis with severe asymmetry and synkinesis, and 100 indicates normal facial function without asymmetry or synkinesis. Higher scores represent better facial nerve function.
Measured: Baseline
FDI (Facial Disability Index):
The Facial Disability Index (FDI) is a patient-reported outcome measure used to assess the impact of facial paralysis on physical function and social well-being. The questionnaire consists of 10 items divided into two subscales: Physical Function (5 items) and Social/Well-being Function (5 items). Each subscale is transformed to a score ranging from 0 to 100, with higher scores indicating better function, less disability, and better health-related quality of life. Participants complete the questionnaire independently according to their perceived level of facial disability.
Measured: Baseline
House-Brackmann Facial Grading System (HBGS)
The House-Brackmann Facial Grading System (HBGS), the Sunnybrook Facial Grading System (SFGS), and the Facial Disability Index (FDI) will be used to evaluate facial nerve function and patient-reported disability. HBGS is a clinician-rated six-grade scale assessing the overall severity of facial nerve dysfunction. The Sunnybrook Facial Grading System provides a composite score (0-100) based on resting symmetry, voluntary facial movements, and synkinesis, with higher scores indicating better facial function. The Facial Disability Index is a patient-reported outcome measure consisting of Physical Function and Social/Well-being subscales (0-100), where higher scores indicate less disability and better quality of life.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Aug 2026
- Study start1 Sep 2026 (estimated)
- Primary completion20 Feb 2027 (estimated)
- Study completion20 Jun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Facial ParalysisStudies of the same condition, open and under way.
- More trials run by Biruni UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 49 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Biruni University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Refika Belen Battal, Biruni University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07780370
- Sponsor's protocol ID
- 2024-BİAEK/20-33
- Status last verified
- Aug 2026
- First submitted
- 19 Aug 2026
- Last updated
- 28 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Relationship Between Video-Based Objective Facial Movement Analysis and Clinical Assessment Scales in Patients With Facial Paralysis
- ClinicalTrials.gov ID
- NCT07780370
- Acronym / sponsor ID
- 2024-BİAEK/20-33
- Conditions
- Facial Paralysis
- Keywords
- Facial Paralysis, Video-Based Analysis, Facial Movement Analysis, Objective Facial Assessment, Clinical Assessment Scales
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 49 participants (estimated)
- Lead sponsor
- Biruni UniversityUniversity, hospital or other
- Study start
- 1 Sep 2026 (estimated)
- Primary completion
- 20 Feb 2027 (estimated)
- Study completion
- 20 Jun 2027 (estimated)
- First posted
- 21 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate facial movements in patients with facial paralysis using video-based objective analysis and to examine the relationship between these video-based measurements and standard clinical assessment scales. Participants will be asked to perform simple facial movements, such as raising the eyebrows, closing the eyes tightly, smiling, showing the teeth, pursing the lips, and puffing the cheeks, while a video recording is taken. Researchers will also evaluate participants' facial function using established clinical rating scales and questionnaires. No medication will be given, no invasive procedures will be performed, and no changes will be made to participants' current treatment. The goal is to contribute to the development of more detailed, objective, and standardized methods for evaluating facial function in patients with facial paralysis.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Facial Paralysis Patients | – | Diagnostic Test: Video-Based Objective Facial Motion AnalysisPatients diagnosed with facial paralysis who underwent a single evaluation session including video-based objective facial motion analysis and clinical facial function assessment scales. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adult patients diagnosed with facial paralysis presenting for clinical evaluation.
Key inclusion criteria (3 listed)
- Diagnosis of facial paralysis (e.g., Bell's palsy)
- Age 18 years and older
- Willing and able to provide informed consent
Key exclusion criteria (3 listed)
- Presence of other neurological or craniofacial conditions affecting facial movement
- Prior facial surgery affecting facial musculature
- Inability to cooperate with video recording or clinical assessment procedures
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Video-Based Objective Facial Motion AnalysisVideo recording of standardized facial movements (eyebrow raise, eye closure, smile, teeth showing, lip pursing, cheek puffing) followed by objective, video-based analysis and comparison with clinical facial assessment scales. This is a non-therapeutic, non-invasive assessment procedure and does not constitute a treatment intervention. | Diagnostic test | Facial Paralysis Patients |
Primary outcome
Agreement Between Video-Based Objective Facial Motion Analysis and Clinical Facial Assessment Scale Scores
Time frame: Single assessment session (Day 1)
The degree of agreement/correlation between facial movement parameters obtained from video-based objective analysis and scores obtained from standardized clinical facial assessment scales, evaluated during the same session.
Sunnybrook Facial Grading System
Time frame: Baseline
The Sunnybrook Facial Grading System (SFGS) is a clinician-rated outcome measure used to assess facial nerve function in individuals with facial paralysis. The scale evaluates three components: resting facial symmetry, voluntary facial movement, and synkinesis. Resting symmetry is assessed in the eye, cheek (nasolabial fold), and mouth regions, while voluntary movement is evaluated during five standardized facial expressions. Synkinesis is scored based on the presence and severity of involuntary associated movements during voluntary facial tasks. The composite score is calculated using the standard Sunnybrook scoring formula and ranges from 0 to 100, where 0 indicates complete facial paralysis with severe asymmetry and synkinesis, and 100 indicates normal facial function without asymmetry or synkinesis. Higher scores represent better facial nerve function.
FDI (Facial Disability Index):
Time frame: Baseline
The Facial Disability Index (FDI) is a patient-reported outcome measure used to assess the impact of facial paralysis on physical function and social well-being. The questionnaire consists of 10 items divided into two subscales: Physical Function (5 items) and Social/Well-being Function (5 items). Each subscale is transformed to a score ranging from 0 to 100, with higher scores indicating better function, less disability, and better health-related quality of life. Participants complete the questionnaire independently according to their perceived level of facial disability.
House-Brackmann Facial Grading System (HBGS)
Time frame: Baseline
The House-Brackmann Facial Grading System (HBGS), the Sunnybrook Facial Grading System (SFGS), and the Facial Disability Index (FDI) will be used to evaluate facial nerve function and patient-reported disability. HBGS is a clinician-rated six-grade scale assessing the overall severity of facial nerve dysfunction. The Sunnybrook Facial Grading System provides a composite score (0-100) based on resting symmetry, voluntary facial movements, and synkinesis, with higher scores indicating better facial function. The Facial Disability Index is a patient-reported outcome measure consisting of Physical Function and Social/Well-being subscales (0-100), where higher scores indicate less disability and better quality of life.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Aug 2026.
- Individual participant dataSharing planned: No
Related trials for Facial Paralysis
Not yet recruiting
Deep-plane Facelift As A Staged Adjunct To Facial Reanimation : Functional And Aesthetic Outcomes in Comparison to Facial Reanimation Alone
Facial Palsy
RecruitingPhase 3
Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients
Vestibular Schwannoma, Facial Nerve Paralysis
Recruiting
Eye-Tracking FP "A Pilot Study of the Quantitative Evaluation of the Attention Paid to Faces With Facial Palsy by the Eye-tracking Technology.
Eye-tracking, Facial Palsy
Not yet recruiting
Mindfulness in Nonflaccid Facial Paralysis
Facial Paralysis
Recruiting
Treatment for "Asymmetric Crying Facies"
Hemifacial Microsomia, Facial Nerve Paralysis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Zeynep Hoşbay, Proff. contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Facial Paralysis, run by Biruni University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 28 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Belen Battal, PT (+90 538 864 00 94, 241119002@st.biruni.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Agreement Between Video-Based Objective Facial Motion Analysis and Clinical Facial Assessment Scale Scores (time frame: Single assessment session (Day 1)). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Aug 2026.