Recurrent Patellar DislocationNCT07785570
Hamstring Versus Quadriceps Tendon Graft for MPFL Reconstruction
An observational study of Recurrent Patellar Dislocation, run by Cairo University at 1 site in Egypt.
Trial summary
This prospective comparative study compared the clinical and radiological outcomes of medial patellofemoral ligament (MPFL) reconstruction using a hamstring tendon graft versus a quadriceps tendon graft in patients with recurrent patellar dislocation. Read more about this study
- Who is it for?
- Ages 18 to 40 years
- Conditions the study is for
- Recurrent Patellar Dislocation
- What is being tested?
- MPFL Reconstruction Using Hamstring Tendon Graft and MPFL Reconstruction Using Quadriceps Tendon Graft
- Type of treatment
- Surgery or procedure
- How many people
- 38 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jun 2018to 1 Jun 2022
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- No healthy volunteers
- Adult
Study population: Patients with recurrent patellar instability who underwent medial patellofemoral ligament reconstruction using either a hamstring tendon graft or a quadriceps tendon graft.
Who may be able to join
- Patients with recurrent patellar dislocation.
- Age from 18 to 40 years.
- Patients indicated for isolated medial patellofemoral ligament (MPFL) reconstruction.
Who cannot join
- Patients with trochlear dysplasia (Dejour B-C-D).
- Patients with clinical evidence of mal-alignment (varus, valgus, flat foot and femoral anteversion).
- Patients with congenital pateller dislocation.
- Patella alta and patella baja.
- Previous quadriceps muscles operation.
- Patients with patellofemoral OA.
- Patients with hypermobility syndrome.
- Patients with associated pathology.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison Between Hamstring Versus Quadriceps Tendon Graft in MPFL Reconstruction for Recurrent Patellar Dislocation
This prospective comparative study compared the clinical and radiological outcomes of medial patellofemoral ligament (MPFL) reconstruction using a hamstring tendon graft versus a quadriceps tendon graft in patients with recurrent patellar dislocation. The study included 38 patients with 40 affected knees who underwent MPFL reconstruction using either a hamstring tendon graft or a quadriceps tendon graft, according to the treating surgeon's preference. Patients were prospectively followed in two groups according to the graft used. Clinical outcomes were assessed using the Kujala, International Knee Documentation Committee (IKDC), and Tegner-Lysholm scores. Radiological assessment included patellar tilt angle and congruence angle. Postoperative complications and recurrent patellar instability were also evaluated.
- Conditions
- Recurrent Patellar Dislocation
- Being tested
- MPFL Reconstruction Using Hamstring Tendon Graft, MPFL Reconstruction Using Quadriceps Tendon Graft
- Keywords
- Patellar Instability, Medial Patellofemoral Ligament, MPFL Reconstruction, Hamstring Tendon Graft, Quadriceps Tendon Graft
- Medical subject headings
- Patellar Dislocation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
MPFL Reconstruction Using Hamstring Tendon GraftProcedure or surgery
Medial patellofemoral ligament reconstruction was performed using an autologous semitendinosus tendon graft. The graft was fixed to the medial aspect of the patella and passed between layers 2 and 3 of the medial knee structures, followed by femoral fixation at the anatomical MPFL insertion.
MPFL Reconstruction Using Quadriceps Tendon GraftProcedure or surgery
Medial patellofemoral ligament reconstruction was performed using a distally based superficial quadriceps tendon graft. The graft remained attached to the superior pole of the patella, was passed between layers 2 and 3 of the medial knee structures, and was fixed at the anatomical femoral insertion of the MPFL.
| Study group | Role | What they receive |
|---|---|---|
| Hamstring Tendon Graft Group | Patients who underwent MPFL reconstruction using a hamstring tendon graft. Receives: Procedure: MPFL Reconstruction Using Hamstring Tendon Graft | |
| Quadriceps Tendon Graft Group | Patients who underwent MPFL reconstruction using a quadriceps tendon graft. Receives: Procedure: MPFL Reconstruction Using Quadriceps Tendon Graft |
What is being measured
The primary outcome is the main question the study is designed to answer.
Kujala score
Functional outcome assessed using the Kujala anterior knee pain scale. The score ranges from 0 to 100, with higher scores indicating better knee function and fewer patellofemoral symptoms.
Measured: 12 months postoperatively
Secondary outcomes (5)
International Knee Documentation Committee (IKDC) Score
Knee function was assessed using the International Knee Documentation Committee (IKDC) score. Scores range from 0 to 100, with higher scores indicating better knee function.
Measured: 12 months postoperatively
Tegner-Lysholm Knee Score
Knee function was assessed using the Tegner-Lysholm knee score. Scores range from 0 to 100, with higher scores indicating better knee function.
Measured: 12 months postoperatively
Patellar Tilt Angle
Patellar tilt angle was measured radiologically to assess patellofemoral alignment before and after MPFL reconstruction.
Measured: 12 months postoperatively
Congruence Angle
Congruence angle was measured radiologically to assess patellofemoral alignment before and after MPFL reconstruction.
Measured: 12 months postoperatively
Incidence of Re-dislocation
Number of cases who experienced re-dislocation after MPFL reconstruction
Measured: 12 months postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Aug 2026
- Study start1 Jun 2018
- Primary completion1 Jun 2022
- Study completion1 Jun 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Recurrent Patellar DislocationStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 38 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mahmoud Ahmed El-Desouky, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07785570
- Sponsor's protocol ID
- N-356-2018
- Status last verified
- Aug 2026
- First submitted
- 21 Aug 2026
- Last updated
- 25 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison Between Hamstring Versus Quadriceps Tendon Graft in MPFL Reconstruction for Recurrent Patellar Dislocation
- ClinicalTrials.gov ID
- NCT07785570
- Acronym / sponsor ID
- N-356-2018
- Conditions
- Recurrent Patellar Dislocation
- Keywords
- Patellar Instability, Medial Patellofemoral Ligament, MPFL Reconstruction, Hamstring Tendon Graft, Quadriceps Tendon Graft
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 38 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jun 2018 (actual)
- Primary completion
- 1 Jun 2022 (actual)
- Study completion
- 1 Jun 2022 (actual)
- First posted
- 25 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective comparative study compared the clinical and radiological outcomes of medial patellofemoral ligament (MPFL) reconstruction using a hamstring tendon graft versus a quadriceps tendon graft in patients with recurrent patellar dislocation. The study included 38 patients with 40 affected knees who underwent MPFL reconstruction using either a hamstring tendon graft or a quadriceps tendon graft, according to the treating surgeon's preference. Patients were prospectively followed in two groups according to the graft used. Clinical outcomes were assessed using the Kujala, International Knee Documentation Committee (IKDC), and Tegner-Lysholm scores. Radiological assessment included patellar tilt angle and congruence angle. Postoperative complications and recurrent patellar instability were also evaluated.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Hamstring Tendon Graft Group | – | Procedure: MPFL Reconstruction Using Hamstring Tendon GraftPatients who underwent MPFL reconstruction using a hamstring tendon graft. |
| Quadriceps Tendon Graft Group | – | Procedure: MPFL Reconstruction Using Quadriceps Tendon GraftPatients who underwent MPFL reconstruction using a quadriceps tendon graft. |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Patients with recurrent patellar instability who underwent medial patellofemoral ligament reconstruction using either a hamstring tendon graft or a quadriceps tendon graft.
Key inclusion criteria (3 listed)
- Patients with recurrent patellar dislocation.
- Age from 18 to 40 years.
- Patients indicated for isolated medial patellofemoral ligament (MPFL) reconstruction.
Key exclusion criteria (8 listed)
- Patients with trochlear dysplasia (Dejour B-C-D).
- Patients with clinical evidence of mal-alignment (varus, valgus, flat foot and femoral anteversion).
- Patients with congenital pateller dislocation.
- Patella alta and patella baja.
- Previous quadriceps muscles operation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| MPFL Reconstruction Using Hamstring Tendon GraftMedial patellofemoral ligament reconstruction was performed using an autologous semitendinosus tendon graft. The graft was fixed to the medial aspect of the patella and passed between layers 2 and 3 of the medial knee structures, followed by femoral fixation at the anatomical MPFL insertion. | Procedure or surgery | Hamstring Tendon Graft Group |
| MPFL Reconstruction Using Quadriceps Tendon GraftMedial patellofemoral ligament reconstruction was performed using a distally based superficial quadriceps tendon graft. The graft remained attached to the superior pole of the patella, was passed between layers 2 and 3 of the medial knee structures, and was fixed at the anatomical femoral insertion of the MPFL. | Procedure or surgery | Quadriceps Tendon Graft Group |
Primary outcome
Kujala score
Time frame: 12 months postoperatively
Functional outcome assessed using the Kujala anterior knee pain scale. The score ranges from 0 to 100, with higher scores indicating better knee function and fewer patellofemoral symptoms.
5 secondary outcomes
International Knee Documentation Committee (IKDC) Score
Time frame: 12 months postoperatively
Tegner-Lysholm Knee Score
Time frame: 12 months postoperatively
Patellar Tilt Angle
Time frame: 12 months postoperatively
Congruence Angle
Time frame: 12 months postoperatively
Incidence of Re-dislocation
Time frame: 12 months postoperatively
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Aug 2026.
- Individual participant dataSharing planned: No
Related trials for Recurrent Patellar Dislocation
Not yet recruiting
Comparison Between Medial Patellofemoral Ligament Reconstruction Alone Versus Combined MPFL & Medial Patellotibial Ligament Reconstruction in the Management of Recurrent Lateral Patellar Dislocation in Children
Recurrent Patellar Displacement, MPFL
RecruitingObservational study
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction
Patellar Dislocation, Recurrent, Patellar Dislocation
Recruiting
Comparison of Dynamic and Static Medial Patellofemoral Ligament Operation Technique for Recurrent Patellar Dislocation
Patellar Instability
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Recurrent Patellar Dislocation, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Kujala score (time frame: 12 months postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Aug 2026.