Healthy VolunteersNCT07786233
Multi-Field-Strength MRI Brain Atlas Construction in Healthy Chinese Population
A study testing Multi-Field-Strength Brain MRI in people with Healthy Volunteers, run by Tang-Du Hospital at 1 site in China.
Trial summary
This prospective imaging study aims to construct a multi-field-strength magnetic resonance imaging (MRI) brain atlas for healthy Chinese adults. Healthy volunteers will undergo standardized brain MRI examinations at multiple magnetic field strengths, including 0.55T, 1.5T, 3T, 5T, and 7T. Read more about this study
- Who is it for?
- Ages 16 to 66 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy Volunteers
- What is being tested?
- Multi-Field-Strength Brain MRI
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 500 participants
- Where
- 1 siteChina
- Study dates
- 1 Jul 2026to 1 Feb 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 to 66 years
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Aged 16 to 66 years.
- Voluntarily participates in the study and provides written informed consent.
- No contraindications to MRI examination and able to cooperate with and complete the MRI examinations.
- Female participants must not be pregnant.
- No current or previous clinical diagnosis of severe neurological or psychiatric disorders, such as schizophrenia, dementia, epilepsy, or severe sequelae of traumatic brain injury.
- No obvious intracranial lesions or structural abnormalities identified on routine MRI examination.
Who cannot join
- Presence of contraindications to MRI examination, including MRI-incompatible implanted metallic or electronic devices, cochlear implants, cardiac pacemakers, intracranial metallic clips, or similar devices.
- Severe claustrophobia preventing completion of the MRI examination.
- Pregnancy.
- Current or previous clinical diagnosis of severe neurological or psychiatric disorders.
- History of severe head trauma, brain tumor, stroke, brain surgery, or other conditions that may substantially affect brain structure or function.
- MRI data of insufficient quality for analysis due to marked discomfort, excessive head motion, or other causes during the examination.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
Tangdu Hospital, Fourth Military Medical University
Xi'an, Shaanxi
Shicao Li, 029-84717761, tangduec@126.com
About this study
This prospective imaging study aims to construct a multi-field-strength magnetic resonance imaging (MRI) brain atlas for healthy Chinese adults. Healthy volunteers will undergo standardized brain MRI examinations at multiple magnetic field strengths, including 0.55T, 1.5T, 3T, 5T, and 7T. Structural, diffusion, functional, and other quantitative MRI data will be acquired and analyzed. The study will characterize the consistency and differences in brain morphology and imaging measurements across field strengths and establish standardized multi-field-strength brain templates and reference data for healthy Chinese adults.
Read the detailed description
This is a prospective multi-field-strength neuroimaging study involving healthy Chinese adults. Eligible participants will undergo standardized brain MRI examinations at 0.55T, 1.5T, 3T, 5T, and 7T according to the study protocol.
MRI acquisitions include structural imaging, diffusion imaging, functional imaging, and quantitative imaging sequences where applicable. Images will undergo standardized preprocessing, registration, segmentation, and quantitative analysis. Multi-field-strength brain templates will be constructed, and anatomical and functional imaging characteristics will be compared across magnetic field strengths.
The study aims to establish normative multi-field-strength MRI reference data and brain atlases for healthy Chinese adults and to evaluate the consistency and field-strength-related differences in brain morphometry, cortical measurements, diffusion characteristics, functional connectivity, and other quantitative MRI parameters.
- Conditions
- Healthy Volunteers
- Being tested
- Multi-Field-Strength Brain MRI
- Keywords
- Healthy Chinese Adults, Brain Atlas, Magnetic Resonance Imaging, Multi-Field-Strength MRI
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Multi-Field-Strength Brain MRIDiagnostic test
Participants will undergo standardized brain MRI examinations at 0.55T, 1.5T, 3T, 5T, and 7T. MRI acquisitions include structural, diffusion, functional, and quantitative imaging sequences according to the study protocol. No therapeutic intervention will be administered
| Study group | Role | What they receive |
|---|---|---|
| Healthy Chinese Adults | Experimental | Healthy Chinese adult volunteers will undergo standardized brain MRI examinations at multiple magnetic field strengths according to the study protocol. Receives: Diagnostic Test: Multi-Field-Strength Brain MRI |
What is being measured
The primary outcome is the main question the study is designed to answer.
Regional Gray Matter Volume Across MRI Field Strengths
Regional gray matter volumes will be quantified from standardized structural MRI data and compared across 0.55T, 1.5T, 3T, 5T, and 7T MRI acquisitions.
Measured: From enrollment through completion of all scheduled multi-field-strength MRI examinations, up to 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Aug 2026
- Study start1 Jul 2026
- Primary completion1 Jul 2027 (estimated)
- Study completion1 Feb 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Healthy VolunteersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 500 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Tang-Du Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Xi'an Jiaotong University
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07786233
- Sponsor's protocol ID
- K202607-43
- Status last verified
- Oct 2026
- First submitted
- 21 Aug 2026
- Last updated
- 15 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Multi-Field-Strength MRI Brain Atlas Construction in Healthy Chinese Population
- ClinicalTrials.gov ID
- NCT07786233
- Acronym / sponsor ID
- K202607-43
- Conditions
- Healthy Volunteers
- Keywords
- Healthy Chinese Adults, Brain Atlas, Magnetic Resonance Imaging, Multi-Field-Strength MRI
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 500 participants (estimated)
- Lead sponsor
- Tang-Du HospitalUniversity, hospital or other
- Collaborators
- Xi'an Jiaotong University
- Study start
- 1 Jul 2026 (actual)
- Primary completion
- 1 Jul 2027 (estimated)
- Study completion
- 1 Feb 2028 (estimated)
- First posted
- 25 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective imaging study aims to construct a multi-field-strength magnetic resonance imaging (MRI) brain atlas for healthy Chinese adults. Healthy volunteers will undergo standardized brain MRI examinations at multiple magnetic field strengths, including 0.55T, 1.5T, 3T, 5T, and 7T. Structural, diffusion, functional, and other quantitative MRI data will be acquired and analyzed. The study will characterize the consistency and differences in brain morphology and imaging measurements across field strengths and establish standardized multi-field-strength brain templates and reference data for healthy Chinese adults.
Detailed description
This is a prospective multi-field-strength neuroimaging study involving healthy Chinese adults. Eligible participants will undergo standardized brain MRI examinations at 0.55T, 1.5T, 3T, 5T, and 7T according to the study protocol.
MRI acquisitions include structural imaging, diffusion imaging, functional imaging, and quantitative imaging sequences where applicable. Images will undergo standardized preprocessing, registration, segmentation, and quantitative analysis. Multi-field-strength brain templates will be constructed, and anatomical and functional imaging characteristics will be compared across magnetic field strengths.
The study aims to establish normative multi-field-strength MRI reference data and brain atlases for healthy Chinese adults and to evaluate the consistency and field-strength-related differences in brain morphometry, cortical measurements, diffusion characteristics, functional connectivity, and other quantitative MRI parameters.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Healthy Chinese Adults | Experimental | Diagnostic Test: Multi-Field-Strength Brain MRIHealthy Chinese adult volunteers will undergo standardized brain MRI examinations at multiple magnetic field strengths according to the study protocol. |
Who may qualify
- Ages
- 16 to 66 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (6 listed)
- Aged 16 to 66 years.
- Voluntarily participates in the study and provides written informed consent.
- No contraindications to MRI examination and able to cooperate with and complete the MRI examinations.
- Female participants must not be pregnant.
- No current or previous clinical diagnosis of severe neurological or psychiatric disorders, such as schizophrenia, dementia, epilepsy, or severe sequelae of traumatic brain injury.
Key exclusion criteria (6 listed)
- Presence of contraindications to MRI examination, including MRI-incompatible implanted metallic or electronic devices, cochlear implants, cardiac pacemakers, intracranial metallic clips, or similar devices.
- Severe claustrophobia preventing completion of the MRI examination.
- Pregnancy.
- Current or previous clinical diagnosis of severe neurological or psychiatric disorders.
- History of severe head trauma, brain tumor, stroke, brain surgery, or other conditions that may substantially affect brain structure or function.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Multi-Field-Strength Brain MRIParticipants will undergo standardized brain MRI examinations at 0.55T, 1.5T, 3T, 5T, and 7T. MRI acquisitions include structural, diffusion, functional, and quantitative imaging sequences according to the study protocol. No therapeutic intervention will be administered | Diagnostic test | Healthy Chinese Adults |
Primary outcome
Regional Gray Matter Volume Across MRI Field Strengths
Time frame: From enrollment through completion of all scheduled multi-field-strength MRI examinations, up to 12 months
Regional gray matter volumes will be quantified from standardized structural MRI data and compared across 0.55T, 1.5T, 3T, 5T, and 7T MRI acquisitions.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Oct 2026.
- Individual participant dataSharing planned: No
Related trials for Healthy Volunteers
Enrolling by invitationObservational study
Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members
Neoplasms, Hematologic Neoplasms
RecruitingObservational study
Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)
Immunosuppression, Periodontal Disease
RecruitingObservational study
Adaptive Optics Retinal Imaging
Eye Diseases, Healthy Volunteers
RecruitingObservational study
Characterization of Diseases With Salivary Gland Involvement
Healthy Volunteer, Sjogren's Syndrome
RecruitingObservational study
Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)
Healthy Volunteers, Non-Healthy/Non-Frail
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Multi-Field-Strength Brain MRI in people with Healthy Volunteers, run by Tang-Du Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 15 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ziheng Zhou (+86 18710574531, 173416171@qq.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Regional Gray Matter Volume Across MRI Field Strengths (time frame: From enrollment through completion of all scheduled multi-field-strength MRI examinations, up to 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Oct 2026; AzTrials last refreshed its copy on 26 Oct 2026.