Postoperative Pain After Arthroscopic Knee SurgeryNCT07790393
Adductor Canal Block Versus Parasartorial Compartment Block for Pain Relief and Recovery After Arthroscopic Knee Surgery
A study testing Meperidine in people with Postoperative Pain After Arthroscopic Knee Surgery, run by Istanbul Medipol University Hospital at 1 site in Turkey (Türkiye).
Trial summary
The goal of this clinical trial is to compare adductor canal block and parasartorial compartment block for pain relief and functional recovery in adults undergoing elective arthroscopic knee surgery. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Postoperative Pain After Arthroscopic Knee Surgery
- What is being tested?
- Meperidine
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- Sep 2026to Jun 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Scheduled for elective unilateral primary arthroscopic knee surgery
Who cannot join
- Revision or bilateral arthroscopic knee surgery
- Surgery performed for trauma or an emergency indication
- Contraindications to regional nerve block, including infection at the injection site, coagulopathy, or inappropriate anticoagulant use
- Allergy to amide-type local anesthetics
- Pre-existing peripheral neuropathy or motor deficit in the limb to be operated on
- Dysfunction of the contralateral limb severe enough to interfere with functional assessments
Show all 9Show fewer
- Chronic opioid use
- Severe cognitive impairment
- Pregnancy or lactation
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Medipol Mega Hastaneler Kompleksi
Istanbul, Bagcilar, 34214
Fatma P Ucar, MD, +905377697281, fpinarucar@gmail.com
About this study
Official title: Comparison of the Effects of Adductor Canal Block and Parasartorial Compartment Block on Postoperative Analgesia and Functional Recovery After Arthroscopic Knee Surgery: A Prospective, Randomized, Double-Blind Study
The goal of this clinical trial is to compare adductor canal block and parasartorial compartment block for pain relief and functional recovery in adults undergoing elective arthroscopic knee surgery. The main questions it aims to answer are:
Which block provides better pain relief at rest and during movement 24 hours after surgery? How do the two blocks compare in opioid use, muscle strength, knee movement, early walking, side effects, and patient satisfaction?
Read more
Researchers will compare participants who receive an adductor canal block with those who receive a parasartorial compartment block to determine whether one technique provides better pain relief and functional recovery while preserving muscle strength.
Participants will:
Be randomly assigned to receive either an ultrasound-guided adductor canal block or an ultrasound-guided parasartorial compartment block Have their pain at rest and during knee movement assessed for 48 hours after surgery Have their opioid use, quadriceps muscle strength, knee movement, walking ability, side effects, and satisfaction evaluated after surgery
- Being tested
- Meperidine
- Keywords
- Adductor Canal Block, Postoperative Pain, Parasartorial Compartment Block
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
MeperidineDrug
If the patient's NRS is 4 or more, 0.5 mg/kg meperidine will be given
| Study group | Role | What they receive |
|---|---|---|
| Adductor Canal Block | Active comparator | Not described Receives: Drug: Meperidine |
| Parasartorial Compartment Block | Active comparator | Not described Receives: Drug: Meperidine |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain at Rest 24 Hours After Surgery
Pain intensity at rest will be assessed using the Numeric Rating Scale, ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Lower scores indicate less pain.
Measured: 24 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Aug 2026
- Study startSep 2026 (estimated)
- Primary completionJun 2027 (estimated)
- Study completionJun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Postoperative Pain After Arthroscopic Knee SurgeryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Care provider, Investigator
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Istanbul Medipol University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fatma Pınar Uçar, Istanbul Medipol University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07790393
- Sponsor's protocol ID
- CemreTez
- Status last verified
- Aug 2026
- First submitted
- 25 Aug 2026
- Last updated
- 27 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be publicly shared because the informed consent process does not include consent for public data sharing and to protect participant confidentiality. Aggregated study results will be reported in scientific publications.
Publications
Gungor H, Atalay YO. Para-sartorial compartments (Pasc) block for knee surgeries: a report of five cases. Minerva Anestesiol. 2023 Jun;89(6):606-608. doi: 10.23736/S0375-9393.23.17124-0. Epub 2023 Feb 8. No abstract available.
PubMed 36752608Pascarella G, Costa F, Del Buono R, Strumia A, Cataldo R, Agro F, Carassiti M. The para-sartorial compartments (PASC) block: a new approach to the femoral triangle block for complete analgesia of the anterior knee. Anaesth Rep. 2022 May 5;10(1):e12165. doi: 10.1002/anr3.12165. eCollection 2022 Jan-Jun. No abstract available.
PubMed 35547556Espelund M, Grevstad U, Jaeger P, Holmich P, Kjeldsen L, Mathiesen O, Dahl JB. Adductor canal blockade for moderate to severe pain after arthroscopic knee surgery: a randomized controlled trial. Acta Anaesthesiol Scand. 2014 Nov;58(10):1220-7. doi: 10.1111/aas.12407.
PubMed 25307707Chen B, Tan M, Li Q, Wang S, Chen D, Zhao M, Cao J. Application of ultrasound-guided single femoral triangle and adductor canal block in arthroscopic knee surgery: a prospective, double-blind, randomized clinical study. BMC Anesthesiol. 2024 May 23;24(1):182. doi: 10.1186/s12871-024-02555-0.
PubMed 38783177
Study at a glance
From the registry record, last updated by the sponsor on 27 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effects of Adductor Canal Block and Parasartorial Compartment Block on Postoperative Analgesia and Functional Recovery After Arthroscopic Knee Surgery: A Prospective, Randomized, Double-Blind Study
- ClinicalTrials.gov ID
- NCT07790393
- Acronym / sponsor ID
- CemreTez
- Keywords
- Adductor Canal Block, Postoperative Pain, Parasartorial Compartment Block
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Istanbul Medipol University HospitalUniversity, hospital or other
- Study start
- Sep 2026 (estimated)
- Primary completion
- Jun 2027 (estimated)
- Study completion
- Jun 2027 (estimated)
- First posted
- 27 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to compare adductor canal block and parasartorial compartment block for pain relief and functional recovery in adults undergoing elective arthroscopic knee surgery. The main questions it aims to answer are:
Which block provides better pain relief at rest and during movement 24 hours after surgery? How do the two blocks compare in opioid use, muscle strength, knee movement, early walking, side effects, and patient satisfaction?
Researchers will compare participants who receive an adductor canal block with those who receive a parasartorial compartment block to determine whether one technique provides better pain relief and functional recovery while preserving muscle strength.
Participants will:
Be randomly assigned to receive either an ultrasound-guided adductor canal block or an ultrasound-guided parasartorial compartment block Have their pain at rest and during knee movement assessed for 48 hours after surgery Have their opioid use, quadriceps muscle strength, knee movement, walking ability, side effects, and satisfaction evaluated after surgery
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, care provider, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Adductor Canal Block | Active comparator | Drug: Meperidine |
| Parasartorial Compartment Block | Active comparator | Drug: Meperidine |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Scheduled for elective unilateral primary arthroscopic knee surgery
Key exclusion criteria (9 listed)
- Revision or bilateral arthroscopic knee surgery
- Surgery performed for trauma or an emergency indication
- Contraindications to regional nerve block, including infection at the injection site, coagulopathy, or inappropriate anticoagulant use
- Allergy to amide-type local anesthetics
- Pre-existing peripheral neuropathy or motor deficit in the limb to be operated on
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| MeperidineIf the patient's NRS is 4 or more, 0.5 mg/kg meperidine will be given | Drug | Adductor Canal Block, Parasartorial Compartment Block |
Primary outcome
Pain at Rest 24 Hours After Surgery
Time frame: 24 hours
Pain intensity at rest will be assessed using the Numeric Rating Scale, ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Lower scores indicate less pain.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Aug 2026.
- Results publication: PubMed 36752608Gungor H, Atalay YO. Para-sartorial compartments (Pasc) block for knee surgeries: a report of five cases. Minerva Anestesiol. 2023 Jun;89(6):606-608. doi: 10.23736/S0375-9393.23.17124-0. Epub 2023 Feb 8. No abstract available.
- Results publication: PubMed 35547556Pascarella G, Costa F, Del Buono R, Strumia A, Cataldo R, Agro F, Carassiti M. The para-sartorial compartments (PASC) block: a new approach to the femoral triangle block for complete analgesia of the anterior knee. Anaesth Rep. 2022 May 5;10(1):e12165. doi: 10.1002/anr3.12165. eCollection 2022 Jan-Jun. No abstract available.
- Results publication: PubMed 25307707Espelund M, Grevstad U, Jaeger P, Holmich P, Kjeldsen L, Mathiesen O, Dahl JB. Adductor canal blockade for moderate to severe pain after arthroscopic knee surgery: a randomized controlled trial. Acta Anaesthesiol Scand. 2014 Nov;58(10):1220-7. doi: 10.1111/aas.12407.
- Results publication: PubMed 38783177Chen B, Tan M, Li Q, Wang S, Chen D, Zhao M, Cao J. Application of ultrasound-guided single femoral triangle and adductor canal block in arthroscopic knee surgery: a prospective, double-blind, randomized clinical study. BMC Anesthesiol. 2024 May 23;24(1):182. doi: 10.1186/s12871-024-02555-0.
- Individual participant dataSharing planned: No. Individual participant data will not be publicly shared because the informed consent process does not include consent for public data sharing and to protect participant confidentiality. Aggregated study results will be reported in scientific publications.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Meperidine in people with Postoperative Pain After Arthroscopic Knee Surgery, run by Istanbul Medipol University Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 27 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Fatma P Ucar, MD (+905377697281, fpinarucar@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain at Rest 24 Hours After Surgery (time frame: 24 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07790393, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Aug 2026.