Kefir Usual Consumers and New Kefir ConsumersKefirSelfNCT07790666
Activia Kefir Consumption in Real-world Setting
An observational study of Kefir Usual Consumers and New Kefir Consumers, run by Danone Global Research & Innovation Center at 3 sites in Spain.
Trial summary
The study aims at generating first real-world insights into how consumers perceive the benefits of consuming Activia Kefir on their digestive wellbeing, overall wellbeing, and to explore its potential effects on the gut microbiome. Read more about this study
- Who is it for?
- Ages 18 to 90 yearsHealthy volunteers can take part
- Conditions the study is for
- Kefir Usual Consumers and New Kefir Consumers
- What is being tested?
- Commercialized dairy product consumption and stool samples collection
- How many people
- 550 participants
- Where
- 3 sitesSpain
- Study dates
- 25 Aug 2026to Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 90 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The study will include male and female participants aged 18 years and older at the time of screening. Both current (Activia) kefir consumers and individuals who are new to (Activia) kefir consumption will be eligible for participation.
Who may be able to join
- Males and females aged 18 years and older at the time of screening;
- Willingness to consume Activia Kefir and complete the requested questionnaires;
- Living in the designated locations in Spain, able to read and write in Spanish;
- Have a personal electronic device compatible and connectable to internet (i.e., computer, laptop, smartphone) to fill the questionnaires;
- Signed informed consent.
Who cannot join
- People that currently participate in another study with (dairy) investigational or marketed products;
- Severely immunocompromised individuals (e.g., post-transplant, advanced HIV/AIDS, undergoing chemotherapy);
- Individuals with known allergies or intolerances to product ingredients. For lactose maldigestion, kefir may improve tolerance, so individuals who are aware of their condition and still wish to participate can be included.
Trial locations and contacts
3 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Danone Global Research & Innovation Center contact
Spain3 sites, 3 recruiting
- Recruiting
Mmr Research Worlwide B.V
Barcelona
- Recruiting
Mmr Research Worlwide B.V
Madrid
- Recruiting
Mmr Research Worlwide B.V
Valencia
About this study
Official title: A Post-launch Study in Spain Assessing Self-perceived Health Benefits and Gut Microbiota Following 2 Weeks Activia Kefir Consumption in Real-world Setting
The study aims at generating first real-world insights into how consumers perceive the benefits of consuming Activia Kefir on their digestive wellbeing, overall wellbeing, and to explore its potential effects on the gut microbiome.
- Being tested
- Commercialized dairy product consumption and stool samples collection
- Keywords
- Digestive wellbeing, Quality of life, Gut Microbiome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Commercialized dairy product consumption and stool samples collectionOther
Consumption of 280 mL (1 bottle) Activia Kefir drinkable per day during the two-weeks study period and collection of 2 stools samples using a collection kit at participant's home (before and after product consumption)
| Study group | Role | What they receive |
|---|---|---|
| Consumers of Activia Kefir | Not described Receives: Other: Commercialized dairy product consumption and stool samples collection |
What is being measured
The primary outcome is the main question the study is designed to answer.
Gastrointestinal (GI)-wellbeing (single-item question)
Difference between after consumption and baseline
Measured: After 2 weeks of study product consumption
Stool consistency (Bristol stool scale, single-item)
Difference between after consumption and baseline
Measured: After 2 weeks of study product consumption
Stool frequency (number of stools/week, single-item)
Difference between after consumption and baseline
Measured: After 2 weeks of study product consumption
Digestive symptoms frequency questionnaire (DSFQ, frequency of 4 symptoms: abdominal pain/discomfort, bloating, flatulence, borborygmi)
Difference between after consumption and baseline
Measured: After 2 weeks of study product consumption
Secondary outcomes (3)
PROMIS global health questionnaire (10-item, includes questions about emotional state fatigue, pain, general health, quality of life, physical health, mental health, satisfaction social activities, usual activities, and everyday physical activities)
Difference between after consumption and baseline
Measured: After 2 weeks of study product consumption
WHO wellbeing questionnaire (5-items, includes questions about cheerful/good spirits, calm/relaxed, active/vigorous, feeling fresh/rested, daily life with things that interest me)
Difference between after consumption and baseline
Measured: After 2 weeks of study product consumption
Perceived resilience (using the 2-item Connor-Davidson Resilience Scale (CD-RISC)-2)
Difference between after consumption and baseline
Measured: After 2 weeks of study product consumption
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Aug 2026
- Study start25 Aug 2026
- Primary completionDec 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Kefir Usual Consumers and New Kefir ConsumersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 550 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Danone Global Research & Innovation Center
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07790666
- Sponsor's protocol ID
- 25REX0093320
- Acronym
- KefirSelf
- Status last verified
- Aug 2026
- First submitted
- 24 Aug 2026
- Last updated
- 31 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Post-launch Study in Spain Assessing Self-perceived Health Benefits and Gut Microbiota Following 2 Weeks Activia Kefir Consumption in Real-world Setting
- ClinicalTrials.gov ID
- NCT07790666
- Acronym / sponsor ID
- KefirSelf / 25REX0093320
- Keywords
- Digestive wellbeing, Quality of life, Gut Microbiome
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 550 participants (estimated)
- Lead sponsor
- Danone Global Research & Innovation CenterIndustry (pharma, biotech, devices)
- Study start
- 25 Aug 2026 (actual)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 27 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study aims at generating first real-world insights into how consumers perceive the benefits of consuming Activia Kefir on their digestive wellbeing, overall wellbeing, and to explore its potential effects on the gut microbiome.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Consumers of Activia Kefir | – | Other: Commercialized dairy product consumption and stool samples collection |
Who may qualify
- Ages
- 18 to 90 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The study will include male and female participants aged 18 years and older at the time of screening. Both current (Activia) kefir consumers and individuals who are new to (Activia) kefir consumption will be eligible for participation.
Key inclusion criteria (5 listed)
- Males and females aged 18 years and older at the time of screening;
- Willingness to consume Activia Kefir and complete the requested questionnaires;
- Living in the designated locations in Spain, able to read and write in Spanish;
- Have a personal electronic device compatible and connectable to internet (i.e., computer, laptop, smartphone) to fill the questionnaires;
- Signed informed consent.
Key exclusion criteria (3 listed)
- People that currently participate in another study with (dairy) investigational or marketed products;
- Severely immunocompromised individuals (e.g., post-transplant, advanced HIV/AIDS, undergoing chemotherapy);
- Individuals with known allergies or intolerances to product ingredients. For lactose maldigestion, kefir may improve tolerance, so individuals who are aware of their condition and still wish to participate can be included.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Commercialized dairy product consumption and stool samples collectionConsumption of 280 mL (1 bottle) Activia Kefir drinkable per day during the two-weeks study period and collection of 2 stools samples using a collection kit at participant's home (before and after product consumption) | Other | Consumers of Activia Kefir |
Primary outcome
Gastrointestinal (GI)-wellbeing (single-item question)
Time frame: After 2 weeks of study product consumption
Difference between after consumption and baseline
Stool consistency (Bristol stool scale, single-item)
Time frame: After 2 weeks of study product consumption
Difference between after consumption and baseline
Stool frequency (number of stools/week, single-item)
Time frame: After 2 weeks of study product consumption
Difference between after consumption and baseline
Digestive symptoms frequency questionnaire (DSFQ, frequency of 4 symptoms: abdominal pain/discomfort, bloating, flatulence, borborygmi)
Time frame: After 2 weeks of study product consumption
Difference between after consumption and baseline
3 secondary outcomes
PROMIS global health questionnaire (10-item, includes questions about emotional state fatigue, pain, general health, quality of life, physical health, mental health, satisfaction social activities, usual activities, and everyday physical activities)
Time frame: After 2 weeks of study product consumption
WHO wellbeing questionnaire (5-items, includes questions about cheerful/good spirits, calm/relaxed, active/vigorous, feeling fresh/rested, daily life with things that interest me)
Time frame: After 2 weeks of study product consumption
Perceived resilience (using the 2-item Connor-Davidson Resilience Scale (CD-RISC)-2)
Time frame: After 2 weeks of study product consumption
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Aug 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Danone Global Research & Innovation Center contact
3 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Kefir Usual Consumers and New Kefir Consumers, run by Danone Global Research & Innovation Center at 3 sites in Spain.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 31 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 3 sites in Spain. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Danone Global Research & Innovation Center (+33 (0)1 69 35 70 00, register.clinicalresearchnutricia@danone.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Gastrointestinal (GI)-wellbeing (single-item question) (time frame: After 2 weeks of study product consumption). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Aug 2026.