Facial Skin Aging and Wrinkle SeverityNCT07792447
Antioxidant Nutrition and Facial Exercise for Skin Aging
A study testing Combined Antioxidant Nutrition and Facial Exercise Program in people with Facial Skin Aging and Wrinkle Severity, run by University of Zakho.
Trial summary
This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women. Participants will be randomly assigned to an intervention group or a control group. Read more about this study
- Who is it for?
- Ages 45 to 50 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Facial Skin Aging and Wrinkle Severity
- What is being tested?
- Combined Antioxidant Nutrition and Facial Exercise Program
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 120 participants
- Where
- No sites listed yet
- Study dates
- 25 Aug 2026to 25 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 50 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- -
- Female participants aged 45-50 years. Willing and able to participate in the 12-week intervention program. Willing to follow the assigned dietary and facial exercise program. Willing to maintain their usual skincare routine unless otherwise instructed by the study protocol. Able to provide informed consent.
Who cannot join
- Current smoking. Facial aesthetic procedures such as botulinum toxin injections, dermal fillers, laser treatment, chemical peels, or similar procedures within the predefined period before enrollment. Current dermatological disease or skin condition that may affect facial skin measurements. Uncontrolled chronic medical conditions that may influence skin health or participation in the intervention. Planned initiation of new skincare treatments, cosmetic products, or aesthetic procedures during the 12-week study period. Inability to perform the facial exercise program safely or comply with the dietary intervention and study procedures
- -
About this study
Official title: Effects of a Combined Antioxidant Nutrition and Facial Exercise Program on Skin Quality and Wrinkle Severity in Middle-Aged Women
This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women. Participants will be randomly assigned to an intervention group or a control group. The intervention group will follow a structured antioxidant-rich dietary program combined with facial exercises, while the control group will maintain their usual lifestyle. Skin quality and wrinkle-related outcomes will be assessed at baseline and after the 12-week intervention using standardized objective measurements
- Conditions
- Facial Skin Aging and Wrinkle Severity
- Being tested
- Combined Antioxidant Nutrition and Facial Exercise Program
- Keywords
- Facial Exercise, Skin Aging, Facial Wrinkles, Middle-Aged Women
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Combined Antioxidant Nutrition and Facial Exercise ProgramBehavioural
Participants in the intervention group will complete a 12-week combined program consisting of an antioxidant-rich dietary intervention and structured facial exercises. The dietary component will emphasize regular consumption of antioxidant-rich foods, while the facial exercise component will target major facial muscle groups according to a standardized exercise protocol. Participants will be instructed to follow the program throughout the 12-week intervention period
| Study group | Role | What they receive |
|---|---|---|
| intervention group | Experimental | Participants in the intervention group will follow a 12-week combined antioxidant-rich nutrition and facial exercise program Receives: Behavioral: Combined Antioxidant Nutrition and Facial Exercise Program |
| control group | No intervention | Participants in the control group will maintain their usual diet, skincare routine, and daily lifestyle without receiving the study intervention during the 12-week period |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Mean Crow's Feet Wrinkle Depth
Change in the mean bilateral crow's feet wrinkle depth from baseline to week 12, assessed using standardized three-dimensional skin imaging. Measurements will be obtained from both sides of the face and averaged to provide the participant-level value. Lower post-intervention values indicate improvement in wrinkle depth
Measured: Baseline to 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Aug 2026
- Study start25 Aug 2026 (estimated)
- Primary completion25 Aug 2026 (estimated)
- Study completion25 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Facial Skin Aging and Wrinkle SeverityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Zakho
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dalshad Mohamed Abdulrehman, University of Zakho
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07792447
- Sponsor's protocol ID
- UOZ-FACE-2026-02
- Status last verified
- Aug 2026
- First submitted
- 25 Aug 2026
- Last updated
- 28 Aug 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) will not be shared because the data contain confidential participant information and were collected under ethical approval with provisions for maintaining participant privacy and confidentiality.
Study at a glance
From the registry record, last updated by the sponsor on 28 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of a Combined Antioxidant Nutrition and Facial Exercise Program on Skin Quality and Wrinkle Severity in Middle-Aged Women
- ClinicalTrials.gov ID
- NCT07792447
- Acronym / sponsor ID
- UOZ-FACE-2026-02
- Conditions
- Facial Skin Aging and Wrinkle Severity
- Keywords
- Facial Exercise, Skin Aging, Facial Wrinkles, Middle-Aged Women
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- University of ZakhoUniversity, hospital or other
- Study start
- 25 Aug 2026 (estimated)
- Primary completion
- 25 Aug 2026 (estimated)
- Study completion
- 25 Nov 2026 (estimated)
- First posted
- 28 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women. Participants will be randomly assigned to an intervention group or a control group. The intervention group will follow a structured antioxidant-rich dietary program combined with facial exercises, while the control group will maintain their usual lifestyle. Skin quality and wrinkle-related outcomes will be assessed at baseline and after the 12-week intervention using standardized objective measurements
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| intervention group | Experimental | Behavioral: Combined Antioxidant Nutrition and Facial Exercise ProgramParticipants in the intervention group will follow a 12-week combined antioxidant-rich nutrition and facial exercise program |
| control group | No intervention | –Participants in the control group will maintain their usual diet, skincare routine, and daily lifestyle without receiving the study intervention during the 12-week period |
Who may qualify
- Ages
- 45 to 50 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- -
- Female participants aged 45-50 years. Willing and able to participate in the 12-week intervention program. Willing to follow the assigned dietary and facial exercise program. Willing to maintain their usual skincare routine unless otherwise instructed by the study protocol. Able to provide informed consent.
Key exclusion criteria (2 listed)
- Current smoking. Facial aesthetic procedures such as botulinum toxin injections, dermal fillers, laser treatment, chemical peels, or similar procedures within the predefined period before enrollment. Current dermatological disease or skin condition that may affect facial skin measurements. Uncontrolled chronic medical conditions that may influence skin health or participation in the intervention. Planned initiation of new skincare treatments, cosmetic products, or aesthetic procedures during the 12-week study period. Inability to perform the facial exercise program safely or comply with the dietary intervention and study procedures
- -
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Combined Antioxidant Nutrition and Facial Exercise ProgramParticipants in the intervention group will complete a 12-week combined program consisting of an antioxidant-rich dietary intervention and structured facial exercises. The dietary component will emphasize regular consumption of antioxidant-rich foods, while the facial exercise component will target major facial muscle groups according to a standardized exercise protocol. Participants will be instructed to follow the program throughout the 12-week intervention period | Behavioural | intervention group |
Primary outcome
Change in Mean Crow's Feet Wrinkle Depth
Time frame: Baseline to 12 weeks
Change in the mean bilateral crow's feet wrinkle depth from baseline to week 12, assessed using standardized three-dimensional skin imaging. Measurements will be obtained from both sides of the face and averaged to provide the participant-level value. Lower post-intervention values indicate improvement in wrinkle depth
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Aug 2026.
- Individual participant dataSharing planned: No. Individual participant data (IPD) will not be shared because the data contain confidential participant information and were collected under ethical approval with provisions for maintaining participant privacy and confidentiality.
Related trials for Facial Skin Aging and Wrinkle Severity
Not yet recruiting
Evaluation of MD60002 Device for Facial Skin Aging
Facial Wrinkles, Skin Aging
Not yet recruiting
Facial Exercise and Daily Habit Modification Program for Skin Quality and Wrinkle Severity in Middle-Aged Women
Facail Skin Aging
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Combined Antioxidant Nutrition and Facial Exercise Program in people with Facial Skin Aging and Wrinkle Severity, run by University of Zakho.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 28 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Mean Crow's Feet Wrinkle Depth (time frame: Baseline to 12 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Aug 2026.