Epiploic AppendagitisNCT07794865
Differentiating Right-sided Epiploic Appendagitis From Diverticulitis
An observational study of Epiploic Appendagitis, run by National Taiwan University Hospital.
Trial summary
This study will perform a retrospective analysis of adult patients who presented to the emergency department of National Taiwan University Hospital, Hsin-Chu and Yun-Lin Branches between January 2022 and December 2025 and were diagnosed with either right-sided epiploic appendagitis or right-sided colonic… Read more about this study
- Who is it for?
- Ages 20 years and older
- Conditions the study is for
- Epiploic Appendagitis
- How many people
- 50 participants
- Where
- No sites listed yet
- Study dates
- 1 Sep 2026to 31 Dec 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: patients more than 20 years with CT-confirmed right-sided epiploic appendagitis
Who may be able to join
- patients more than 20 years, with CT-confirmed right-sided epiploic appendagitis
Who cannot join
- patients less than 20 years with other abdominal pathologies
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Differentiating Right-sided Epiploic Appendagitis From Diverticulitis: A Retrospective Analysis of Clinical Presentation, Imaging Characteristics, and Outcomes
This study will perform a retrospective analysis of adult patients who presented to the emergency department of National Taiwan University Hospital, Hsin-Chu and Yun-Lin Branches between January 2022 and December 2025 and were diagnosed with either right-sided epiploic appendagitis or right-sided colonic diverticulitis based on CT findings. Clinical presentations, laboratory data, ultrasound and CT imaging characteristics, treatment strategies, and clinical outcomes will be compared between the two groups. The study aims to identify imaging and clinical features that may facilitate the rapid differentiation of these two conditions in the emergency department.
Read the detailed description
Right-sided epiploic appendagitis and right-sided colonic diverticulitis are common differential diagnoses in patients presenting with right lower quadrant abdominal pain in the emergency department. Because the two conditions share many similar clinical manifestations, misdiagnosis is common. Epiploic appendagitis is a benign and self-limiting disease; however, when misdiagnosed as diverticulitis, it may lead to unnecessary hospitalization, antibiotic treatment, or even surgical intervention, resulting in increased healthcare utilization and patient burden. Although computed tomography (CT) is currently considered the gold standard for diagnosing both conditions, identifying distinguishing clinical features may facilitate accurate diagnosis and appropriate management.
This study will perform a retrospective analysis of adult patients who presented to the emergency department of National Taiwan University Hospital, Hsin-Chu and Yun-Lin Branches between January 2022 and December 2025 and were diagnosed with either right-sided epiploic appendagitis or right-sided colonic diverticulitis based on CT findings. Clinical presentations, laboratory data, ultrasound and CT imaging characteristics, treatment strategies, and clinical outcomes will be compared between the two groups. The study aims to identify imaging and clinical features that may facilitate the rapid differentiation of these two conditions in the emergency department.
- Conditions
- Epiploic Appendagitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| EA case | patients with right-sided epiploic appendagitis | |
| diverticulitis control | patients with right-sided diverticulitis |
What is being measured
The primary outcome is the main question the study is designed to answer.
clinical parameters
physiological parameters
Measured: one year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Aug 2026
- Study start1 Sep 2026 (estimated)
- Primary completion31 Dec 2028 (estimated)
- Study completion31 Dec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Epiploic AppendagitisStudies of the same condition, open and under way.
- More trials run by National Taiwan University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Taiwan University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Wan-Ching Lien, Principal investigator, Wan-Ching Lien, attending physician, National Taiwan University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07794865
- Sponsor's protocol ID
- 202607108RINE
- Status last verified
- Aug 2026
- First submitted
- 23 Aug 2026
- Last updated
- 31 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Differentiating Right-sided Epiploic Appendagitis From Diverticulitis: A Retrospective Analysis of Clinical Presentation, Imaging Characteristics, and Outcomes
- ClinicalTrials.gov ID
- NCT07794865
- Acronym / sponsor ID
- 202607108RINE
- Conditions
- Epiploic Appendagitis
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- National Taiwan University HospitalUniversity, hospital or other
- Study start
- 1 Sep 2026 (estimated)
- Primary completion
- 31 Dec 2028 (estimated)
- Study completion
- 31 Dec 2028 (estimated)
- First posted
- 31 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will perform a retrospective analysis of adult patients who presented to the emergency department of National Taiwan University Hospital, Hsin-Chu and Yun-Lin Branches between January 2022 and December 2025 and were diagnosed with either right-sided epiploic appendagitis or right-sided colonic diverticulitis based on CT findings. Clinical presentations, laboratory data, ultrasound and CT imaging characteristics, treatment strategies, and clinical outcomes will be compared between the two groups. The study aims to identify imaging and clinical features that may facilitate the rapid differentiation of these two conditions in the emergency department.
Detailed description
Right-sided epiploic appendagitis and right-sided colonic diverticulitis are common differential diagnoses in patients presenting with right lower quadrant abdominal pain in the emergency department. Because the two conditions share many similar clinical manifestations, misdiagnosis is common. Epiploic appendagitis is a benign and self-limiting disease; however, when misdiagnosed as diverticulitis, it may lead to unnecessary hospitalization, antibiotic treatment, or even surgical intervention, resulting in increased healthcare utilization and patient burden. Although computed tomography (CT) is currently considered the gold standard for diagnosing both conditions, identifying distinguishing clinical features may facilitate accurate diagnosis and appropriate management.
This study will perform a retrospective analysis of adult patients who presented to the emergency department of National Taiwan University Hospital, Hsin-Chu and Yun-Lin Branches between January 2022 and December 2025 and were diagnosed with either right-sided epiploic appendagitis or right-sided colonic diverticulitis based on CT findings. Clinical presentations, laboratory data, ultrasound and CT imaging characteristics, treatment strategies, and clinical outcomes will be compared between the two groups. The study aims to identify imaging and clinical features that may facilitate the rapid differentiation of these two conditions in the emergency department.
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| EA case | – | –patients with right-sided epiploic appendagitis |
| diverticulitis control | – | –patients with right-sided diverticulitis |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- patients more than 20 years with CT-confirmed right-sided epiploic appendagitis
Key inclusion criteria (1 listed)
- patients more than 20 years, with CT-confirmed right-sided epiploic appendagitis
Key exclusion criteria (1 listed)
- patients less than 20 years with other abdominal pathologies
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
clinical parameters
Time frame: one year
physiological parameters
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Aug 2026.
- Individual participant dataSharing planned: No
Related trials for Epiploic Appendagitis
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Wan-Ching Lien principal investigator
Wan-Ching Lien, attending physician, National Taiwan University Hospital
Questions about this trial
What is this clinical trial studying?
An observational study of Epiploic Appendagitis, run by National Taiwan University Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 31 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Wan-Ching Lien, Professor (+886-2-23123456, wanchinglien@ntu.edu.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
clinical parameters (time frame: one year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Aug 2026.