Postoperative PainNCT07796828
Analgesic Outcomes of Ultrasound-Guided QLB vs TAP Block in Midline Laparotomy
A study testing Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Ultrasound-Guided Transversus Abdominis Plane Block and Bupivacaine 0.25% in people with Postoperative Pain and Midline Laparotomy, run by Sheikh Zayed Medical College at 1 site in Pakistan.
Trial summary
This randomized controlled trial compares the analgesic efficacy of ultrasound-guided bilateral lateral quadratus lumborum block (QLB, QL1) versus ultrasound-guided bilateral transversus abdominis plane (TAP) block in adults undergoing elective midline laparotomy under general anesthesia. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Postoperative Pain, Midline Laparotomy, Abdominal Surgery
- What is being tested?
- Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Ultrasound-Guided Transversus Abdominis Plane Block and Bupivacaine 0.25%
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 sitePakistan
- Study dates
- Sep 2026to Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age 18-65 years
- Either sex
- Scheduled for elective midline laparotomy (upper, lower, or full midline incision) under general anesthesia
- ASA physical status I-III
Who cannot join
- Body mass index >40 kg/m²
- Existing chronic pain disorder, established opioid dependence, or history of substance abuse
- Previous or current neurological or psychiatric illness likely to compromise comprehension, decision-making capacity, or reliable reporting of pain scores
- Conditions in which an abdominal wall block would not be appropriate or safe (bleeding tendency, ongoing anticoagulation outside acceptable limits, local skin or soft-tissue infection at the planned puncture site, or major distortion of abdominal wall anatomy)
- Urgent laparotomy performed for peritonitis or unstable physiology (including patients requiring continuous vasopressor support)
- Previous abdominal wall surgery, large incisional hernia, or distorted flank/anterior abdominal wall anatomy likely to impair standardized block placement
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site
Sheikh Zayed Medical College/Hospital
Rahim Yar Khan, Punjab Province
Kiran Azhar, 03216220839, azharkiran136@gmail.com
Kiran Azhar, MBBS, FCPS-II (Anesthesia) PGR
About this study
Official title: Analgesic Outcomes of Ultrasound Guided Quadratus Lumborum Block Compared With Transversus Abdominis Plane Block in Patients Undergoing Midline Laparotomy
This randomized controlled trial compares the analgesic efficacy of ultrasound-guided bilateral lateral quadratus lumborum block (QLB, QL1) versus ultrasound-guided bilateral transversus abdominis plane (TAP) block in adults undergoing elective midline laparotomy under general anesthesia. The primary focus is postoperative pain intensity, time to first rescue analgesia, proportion requiring rescue analgesia, and total opioid consumption in the first 24 hours.
Read the detailed description
Midline laparotomy is associated with significant postoperative pain that can limit mobilization, impair respiratory function, and increase opioid-related side effects. Abdominal wall blocks such as the transversus abdominis plane (TAP) block and quadratus lumborum block (QLB) are used as part of multimodal analgesia. TAP primarily targets somatic afferents of the anterior abdominal wall, while QLB may provide broader coverage including potential paravertebral spread via the thoracolumbar fascia, potentially offering longer-lasting analgesia.
This single-center, prospective, randomized controlled trial will enroll 100 adults (50 per group) aged 18-65 years, ASA physical status I-III, scheduled for elective midline laparotomy under general anesthesia. Participants will be randomized 1:1 using sequentially numbered, opaque, sealed envelopes prepared by an independent research assistant. Both blocks will be performed after induction of general anesthesia and before surgical incision by an experienced anesthesiologist under ultrasound guidance and strict aseptic precautions.
Group A (QLB): Bilateral lateral quadratus lumborum (QL1) block with 20 mL of 0.25% bupivacaine per side (total 40 mL / 100 mg, not exceeding 2 mg/kg).
Group B (TAP): Bilateral TAP block with 20 mL of 0.25% bupivacaine per side (total 40 mL / 100 mg, not exceeding 2 mg/kg).
Postoperative analgesia will be standardized with intravenous paracetamol 1 g every 6 hours. Pain will be assessed using the Numerical Rating Scale (NRS 0-10) at 6, 12, and 24 hours by an independent, blinded outcome assessor. Rescue analgesia (intravenous morphine or tramadol) will be given for NRS ≥4. Primary and secondary analgesic outcomes include NRS scores, time to first rescue analgesia, proportion requiring rescue analgesia within 24 hours, and total opioid consumption in the first 24 hours. Block-related complications will also be recorded.
Statistical analysis will use SPSS version 26. Normality will be assessed by Shapiro-Wilk test. Continuous variables will be compared with independent-samples t-test or Mann-Whitney U test; categorical variables with Chi-square or Fisher's exact test. Potential confounders will be addressed by stratification. A two-sided p-value ≤0.05 will be considered statistically significant.
- Conditions
- Postoperative Pain, Midline Laparotomy, Abdominal Surgery
- Being tested
- Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Ultrasound-Guided Transversus Abdominis Plane Block, Bupivacaine 0.25%
- Keywords
- Quadratus Lumborum Block, Transversus Abdominis Plane Block, Ultrasound-Guided Regional Anesthesia, Postoperative Analgesia, Midline Laparotomy, Multimodal Analgesia
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1)Procedure or surgery
Also called QLB, QL1 Block
After induction of general anesthesia and before surgical incision, under strict aseptic precautions, a low-frequency curvilinear ultrasound transducer is placed between the costal margin and iliac crest. An echogenic 22-gauge 80-100 mm block needle is advanced in-plane toward the anterolateral border of the quadratus lumborum muscle near the junction of the transversus abdominis aponeurosis and transversalis fascia. After hydrodissection and negative aspiration, 20 mL of 0.25% bupivacaine is injected on each side under continuous ultrasound visualization of local anesthetic spread. Total planned volume 40 mL (100 mg bupivacaine), not exceeding 2 mg/kg.
Ultrasound-Guided Transversus Abdominis Plane BlockProcedure or surgery
Also called TAP Block, TAPB
After induction of general anesthesia and before surgical incision, under strict aseptic precautions, a high-frequency linear ultrasound transducer is placed transversely on the anterolateral abdominal wall between the costal margin and iliac crest. The external oblique, internal oblique, and transversus abdominis muscles are identified. An echogenic 22-gauge block needle is advanced in-plane until the tip lies in the fascial plane between the internal oblique and transversus abdominis muscles. After hydrodissection and negative aspiration, 20 mL of 0.25% bupivacaine is injected on each side under continuous ultrasound visualization of local anesthetic spread. Total planned volume 40 mL (100 mg bupivacaine), not exceeding 2 mg/kg.
Bupivacaine 0.25%Drug
Local anesthetic used for both QLB and TAP blocks: 20 mL of 0.25% bupivacaine per side (total 40 mL / 100 mg), dose adjusted not to exceed 2 mg/kg body weight.
| Study group | Role | What they receive |
|---|---|---|
| Group A: Quadratus Lumborum Block (QLB) | Experimental | Participants receive bilateral ultrasound-guided lateral quadratus lumborum (QL1) block after induction of general anesthesia and before surgical incision. 20 mL of 0.25% bupivacaine is injected on each side (total 40 mL / 100 mg, dose not exceeding 2 mg/kg). Receives: Procedure: Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1); Drug: Bupivacaine 0.25% |
| Group B: Transversus Abdominis Plane Block (TAPB) | Active comparator | Participants receive bilateral ultrasound-guided transversus abdominis plane block after induction of general anesthesia and before surgical incision. 20 mL of 0.25% bupivacaine is injected on each side (total 40 mL / 100 mg, dose not exceeding 2 mg/kg). Receives: Procedure: Ultrasound-Guided Transversus Abdominis Plane Block; Drug: Bupivacaine 0.25% |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative pain intensity at 12 hours
Pain intensity measured using the Numerical Rating Scale (NRS; 0 = no pain, 10 = worst imaginable pain) assessed by an independent blinded outcome assessor.
Measured: 12 hours after completion of surgery
Secondary outcomes (6)
Postoperative pain intensity at 6 hours
Pain intensity measured using the Numerical Rating Scale (NRS 0-10) by an independent blinded outcome assessor.
Measured: 6 hours after completion of surgery
Postoperative pain intensity at 24 hours
Pain intensity measured using the Numerical Rating Scale (NRS 0-10) by an independent blinded outcome assessor.
Measured: 24 hours after completion of surgery
Time to first rescue analgesia
Time (in minutes or hours) from completion of surgery to the first administration of rescue analgesia for NRS score ≥4.
Measured: From completion of surgery up to 24 hours postoperatively
Proportion of participants requiring rescue analgesia within 24 hours
Percentage of participants who receive at least one dose of rescue analgesia (for NRS ≥4) within the first 24 postoperative hours.
Measured: First 24 hours after surgery
Total opioid/rescue analgesic consumption within 24 hours
Cumulative dose of opioid or rescue analgesic administered within the first 24 postoperative hours, recorded from the medication administration record.
Measured: First 24 hours after surgery
Incidence of block-related complications
Any complication considered related to QLB or TAP block (e.g., local anesthetic systemic toxicity, hematoma, infection, nerve injury, block failure).
Measured: During block performance and within 24 hours after the block
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Sep 2026
- Study startSep 2026 (estimated)
- Primary completionMar 2027 (estimated)
- Study completionMar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sheikh Zayed Medical College
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Kiran Azhar, Sheikh Zayed Medical College
- Investigators
- Kiran Azhar, MBBS, FCPS-II (Anesthesia) PGR, Principal investigator, Department of Anesthesiology & ICU, Sheikh Zayed Medical College/Hospital, Rahim Yar KhanSairah Sadaf, FCPS, Study chair, Department of Anesthesiology & ICU, Sheikh Zayed Medical College/Hospital, Rahim Yar Khan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07796828
- Sponsor's protocol ID
- 148/IRB/S.ZMC/SZH
- Other IDs
- 148/IRB/SZMC/SZH
- Status last verified
- Aug 2026
- First submitted
- 27 Aug 2026
- Last updated
- 1 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared.
Publications
Gnanasekar N, Kumar GD, Kurhekar P, Raghuraman MS, Prasad TK. Comparative Evaluation of Ropivacaine and Ropivacaine with Dexamethasone in Transverse Abdominis Plane Block for Lower Abdominal Surgeries: A Prospective, Randomized, Double-Blinded Study. Anesth Essays Res. 2018 Oct-Dec;12(4):937-942. doi: 10.4103/aer.AER_162_18.
PubMed 30662134Dai J, Lin S, Cui X, Xu Z, Zheng R, Wu D. The effects of ultrasound-guided QLB and TAPB combined with opioid-free anesthesia (OFA) on clinical efficacy of the patients undergoing abdominal surgery. Heliyon. 2023 Oct 11;9(10):e20878. doi: 10.1016/j.heliyon.2023.e20878. eCollection 2023 Oct.
PubMed 37867884
Study at a glance
From the registry record, last updated by the sponsor on 1 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Analgesic Outcomes of Ultrasound Guided Quadratus Lumborum Block Compared With Transversus Abdominis Plane Block in Patients Undergoing Midline Laparotomy
- ClinicalTrials.gov ID
- NCT07796828
- Acronym / sponsor ID
- 148/IRB/S.ZMC/SZH
- Conditions
- Postoperative Pain, Midline Laparotomy, Abdominal Surgery
- Keywords
- Quadratus Lumborum Block, Transversus Abdominis Plane Block, Ultrasound-Guided Regional Anesthesia, Postoperative Analgesia, Midline Laparotomy, Multimodal Analgesia
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Sheikh Zayed Medical CollegeOther government
- Study start
- Sep 2026 (estimated)
- Primary completion
- Mar 2027 (estimated)
- Study completion
- Mar 2027 (estimated)
- First posted
- 1 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial compares the analgesic efficacy of ultrasound-guided bilateral lateral quadratus lumborum block (QLB, QL1) versus ultrasound-guided bilateral transversus abdominis plane (TAP) block in adults undergoing elective midline laparotomy under general anesthesia. The primary focus is postoperative pain intensity, time to first rescue analgesia, proportion requiring rescue analgesia, and total opioid consumption in the first 24 hours.
Detailed description
Midline laparotomy is associated with significant postoperative pain that can limit mobilization, impair respiratory function, and increase opioid-related side effects. Abdominal wall blocks such as the transversus abdominis plane (TAP) block and quadratus lumborum block (QLB) are used as part of multimodal analgesia. TAP primarily targets somatic afferents of the anterior abdominal wall, while QLB may provide broader coverage including potential paravertebral spread via the thoracolumbar fascia, potentially offering longer-lasting analgesia.
This single-center, prospective, randomized controlled trial will enroll 100 adults (50 per group) aged 18-65 years, ASA physical status I-III, scheduled for elective midline laparotomy under general anesthesia. Participants will be randomized 1:1 using sequentially numbered, opaque, sealed envelopes prepared by an independent research assistant. Both blocks will be performed after induction of general anesthesia and before surgical incision by an experienced anesthesiologist under ultrasound guidance and strict aseptic precautions.
Group A (QLB): Bilateral lateral quadratus lumborum (QL1) block with 20 mL of 0.25% bupivacaine per side (total 40 mL / 100 mg, not exceeding 2 mg/kg).
Group B (TAP): Bilateral TAP block with 20 mL of 0.25% bupivacaine per side (total 40 mL / 100 mg, not exceeding 2 mg/kg).
Postoperative analgesia will be standardized with intravenous paracetamol 1 g every 6 hours. Pain will be assessed using the Numerical Rating Scale (NRS 0-10) at 6, 12, and 24 hours by an independent, blinded outcome assessor. Rescue analgesia (intravenous morphine or tramadol) will be given for NRS ≥4. Primary and secondary analgesic outcomes include NRS scores, time to first rescue analgesia, proportion requiring rescue analgesia within 24 hours, and total opioid consumption in the first 24 hours. Block-related complications will also be recorded.
Statistical analysis will use SPSS version 26. Normality will be assessed by Shapiro-Wilk test. Continuous variables will be compared with independent-samples t-test or Mann-Whitney U test; categorical variables with Chi-square or Fisher's exact test. Potential confounders will be addressed by stratification. A two-sided p-value ≤0.05 will be considered statistically significant.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A: Quadratus Lumborum Block (QLB) | Experimental | Procedure: Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Drug: Bupivacaine 0.25%Participants receive bilateral ultrasound-guided lateral quadratus lumborum (QL1) block after induction of general anesthesia and before surgical incision. 20 mL of 0.25% bupivacaine is injected on each side (total 40 mL / 100 mg, dose not exceeding 2 mg/kg). |
| Group B: Transversus Abdominis Plane Block (TAPB) | Active comparator | Procedure: Ultrasound-Guided Transversus Abdominis Plane Block, Drug: Bupivacaine 0.25%Participants receive bilateral ultrasound-guided transversus abdominis plane block after induction of general anesthesia and before surgical incision. 20 mL of 0.25% bupivacaine is injected on each side (total 40 mL / 100 mg, dose not exceeding 2 mg/kg). |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Age 18-65 years
- Either sex
- Scheduled for elective midline laparotomy (upper, lower, or full midline incision) under general anesthesia
- ASA physical status I-III
Key exclusion criteria (6 listed)
- Body mass index >40 kg/m²
- Existing chronic pain disorder, established opioid dependence, or history of substance abuse
- Previous or current neurological or psychiatric illness likely to compromise comprehension, decision-making capacity, or reliable reporting of pain scores
- Conditions in which an abdominal wall block would not be appropriate or safe (bleeding tendency, ongoing anticoagulation outside acceptable limits, local skin or soft-tissue infection at the planned puncture site, or major distortion of abdominal wall anatomy)
- Urgent laparotomy performed for peritonitis or unstable physiology (including patients requiring continuous vasopressor support)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1)Also: QLB, QL1 BlockAfter induction of general anesthesia and before surgical incision, under strict aseptic precautions, a low-frequency curvilinear ultrasound transducer is placed between the costal margin and iliac crest. An echogenic 22-gauge 80-100 mm block needle is advanced in-plane toward the anterolateral border of the quadratus lumborum muscle near the junction of the transversus abdominis aponeurosis and transversalis fascia. After hydrodissection and negative aspiration, 20 mL of 0.25% bupivacaine is injected on each side under continuous ultrasound visualization of local anesthetic spread. Total planned volume 40 mL (100 mg bupivacaine), not exceeding 2 mg/kg. | Procedure or surgery | Group A: Quadratus Lumborum Block (QLB) |
| Ultrasound-Guided Transversus Abdominis Plane BlockAlso: TAP Block, TAPBAfter induction of general anesthesia and before surgical incision, under strict aseptic precautions, a high-frequency linear ultrasound transducer is placed transversely on the anterolateral abdominal wall between the costal margin and iliac crest. The external oblique, internal oblique, and transversus abdominis muscles are identified. An echogenic 22-gauge block needle is advanced in-plane until the tip lies in the fascial plane between the internal oblique and transversus abdominis muscles. After hydrodissection and negative aspiration, 20 mL of 0.25% bupivacaine is injected on each side under continuous ultrasound visualization of local anesthetic spread. Total planned volume 40 mL (100 mg bupivacaine), not exceeding 2 mg/kg. | Procedure or surgery | Group B: Transversus Abdominis Plane Block (TAPB) |
| Bupivacaine 0.25%Local anesthetic used for both QLB and TAP blocks: 20 mL of 0.25% bupivacaine per side (total 40 mL / 100 mg), dose adjusted not to exceed 2 mg/kg body weight. | Drug | Group A: Quadratus Lumborum Block (QLB), Group B: Transversus Abdominis Plane Block (TAPB) |
Primary outcome
Postoperative pain intensity at 12 hours
Time frame: 12 hours after completion of surgery
Pain intensity measured using the Numerical Rating Scale (NRS; 0 = no pain, 10 = worst imaginable pain) assessed by an independent blinded outcome assessor.
6 secondary outcomes
Postoperative pain intensity at 6 hours
Time frame: 6 hours after completion of surgery
Postoperative pain intensity at 24 hours
Time frame: 24 hours after completion of surgery
Time to first rescue analgesia
Time frame: From completion of surgery up to 24 hours postoperatively
Proportion of participants requiring rescue analgesia within 24 hours
Time frame: First 24 hours after surgery
Total opioid/rescue analgesic consumption within 24 hours
Time frame: First 24 hours after surgery
Incidence of block-related complications
Time frame: During block performance and within 24 hours after the block
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Sep 2026.
- Background: PubMed 30662134Gnanasekar N, Kumar GD, Kurhekar P, Raghuraman MS, Prasad TK. Comparative Evaluation of Ropivacaine and Ropivacaine with Dexamethasone in Transverse Abdominis Plane Block for Lower Abdominal Surgeries: A Prospective, Randomized, Double-Blinded Study. Anesth Essays Res. 2018 Oct-Dec;12(4):937-942. doi: 10.4103/aer.AER_162_18.
- Background: PubMed 37867884Dai J, Lin S, Cui X, Xu Z, Zheng R, Wu D. The effects of ultrasound-guided QLB and TAPB combined with opioid-free anesthesia (OFA) on clinical efficacy of the patients undergoing abdominal surgery. Heliyon. 2023 Oct 11;9(10):e20878. doi: 10.1016/j.heliyon.2023.e20878. eCollection 2023 Oct.
- Individual participant dataSharing planned: No. Individual participant data will not be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Kiran Azhar, MBBS, FCPS-II (Anesthesia) PGR principal investigator
Department of Anesthesiology & ICU, Sheikh Zayed Medical College/Hospital, Rahim Yar Khan
Sairah Sadaf, FCPS study chair
Department of Anesthesiology & ICU, Sheikh Zayed Medical College/Hospital, Rahim Yar Khan
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Ultrasound-Guided Transversus Abdominis Plane Block and Bupivacaine 0.25% in people with Postoperative Pain and Midline Laparotomy, run by Sheikh Zayed Medical College at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 1 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Kiran Azhar, MBBS (03216220839, azharkiran136@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative pain intensity at 12 hours (time frame: 12 hours after completion of surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07796828, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Sep 2026.